Lila Segal's Books

Metropolitan Jews

Politics, Race, and Religion in Postwar Detroit

By: Lila Corwin Berman

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Metropolitan Jews

Politics, Race, and Religion in Postwar Detroit

By: Lila Corwin Berman

In this provocative urban history, Lila Corwin Berman considers the role that Detroit s Jews have played in the city s well-known narratives of migration and decline. Like other Detroiters in the 1960s and 1970s, Jews left the city for the suburbs in large numbers. But Berman makes the case that they nevertheless constituted themselves as urban people, and she shows how complex spatial and political relationships existed within the greater metropolitan region. By insisting on the existence and influence of a metropolitan consciousness, Berman reveals the complexity and contingency of what did and didn t change as regions expanded in the postwar era.

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Page Count

333

Publisher

University of Chicago Press

Published Date

ISBN 10

022624783X

ISBN 13

9780226247830

Genocide

Stand by Or Intervene?

By: Lila Perl

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Genocide

Stand by Or Intervene?

By: Lila Perl

This engaging series examines various controversial topics present in today's society.

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Page Count

132

Publisher

Marshall Cavendish

Published Date

ISBN 10

0761449000

ISBN 13

9780761449003

Therapeutic Antibody Engineering

Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry

By: William R Strohl,Lila M Strohl

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Therapeutic Antibody Engineering

Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry

By: William R Strohl,Lila M Strohl

The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering. - Goes beyond the standard engineering issues covered by most books and delves into structure-function relationships - Integration of knowledge across all areas of antibody engineering, development, and marketing - Discusses how current and future genetic engineering of cell lines will pave the way for much higher productivity

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Page Count

697

Publisher

Elsevier

Published Date

ISBN 10

1908818093

ISBN 13

9781908818096

Structure And Action Of Molecular Chaperones: Machines That Assist Protein Folding In The Cell

By: Lila M Gierasch,Arthur L Horwich,Christine Slingsby,Sue Wickner,David Agard

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Structure And Action Of Molecular Chaperones: Machines That Assist Protein Folding In The Cell

By: Lila M Gierasch,Arthur L Horwich,Christine Slingsby,Sue Wickner,David Agard

This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the cell. Ranging from multisubunit ring-shaped chaperonin and Hsp100 machines that use their central cavities to bind and compartmentalize action on proteins, to machines that use other topologies of recognition — binding cellular proteins in an archway or at the surface of a 'clamp' or at the surface of a globular assembly — the structures show us the ways and means the cell has devised to assist its major effectors, proteins, to reach and maintain their unique active forms, as well as, when required, to disrupt protein structure in order to remodel or degrade. Each type of chaperone is beautifully illustrated by X-ray and EM structure determinations at near- atomic level resolution and described by a leader in the study of the respective family. The beauty of what Mother Nature has devised to accomplish essential assisting actions for proteins in vivo is fully appreciable.

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Page Count

328

Publisher

World Scientific

Published Date

ISBN 10

9814749346

ISBN 13

9789814749343

Say Say Say

A Novel

By: Lila Savage

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Say Say Say

A Novel

By: Lila Savage

This is a Borzoi book"--Copyright page.

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Page Count

178

Publisher

Knopf

Published Date

ISBN 10

0525655921

ISBN 13

9780525655923

Book's by Lila Segal

Metropolitan Jews

Metropolitan Jews

Genocide

Genocide

Therapeutic Antibody Engineering

Therapeutic Antibody Engineering

Structure And Action Of Molecular Chaperones: Machines That Assist Protein Folding In The Cell

Structure And Action Of Molecular Chaperones: Machines That Assist Protein Folding In The Cell

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Say Say Say

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