The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts. Features: Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development Additional chapters for this edition include: o Physiological factors related to drug absorption o Approaches to pharmacokinetics and pharmacodynamics calculations o Novel and complex dosage Forms o Clinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products o Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development Additional information on drug therapy, drug product performance, and other related topics Frequently asked questions, practice problems, clinical examples and learning questions
Generic Drug Product Development: Specialty Dosage Forms explores the issues related to providing evidence of pharmaceutical equivalence and bioequivalence for specialty drug products. It describes various scientific approaches and regulatory requirements for manufacturers who need to demonstrate the therapeutic equivalence of generic specialty dru
The assessment of bioequivalence is an important process whereby the bioavailability of a generic drug product is compared with its brand-name counterpart. Generic pharmaceutical products must be approved as therapeutic equivalents to the brand name alternative in order to be interchangeable. The demonstration of bioequivalence is an important comp
In a small village, there stands a very tall tree, with leaves of many different colors, shapes, and sizes. The Rainbow Trees leaves reflect the sun rays into everyones home and make the villagers happy. But nearby, in small black cottage with a big black fence and black furniture, there lives an old woman, eating black bean soup and dark pumpernickel bread. Everything is dark and gloomy for her, and she is sad and lonely, for no one in the village has visited her for more than one hundred years. One night, when no one is around, the old woman paints the leaves of the Rainbow Tree black, which makes the villagers sad and gloomy. The villagers are afraid of the old woman, but a small boy named Miguel decides to go visit her anyway. Can Miguel find a way to bring back the Rainbow Trees colorsand help the people of the village learn a valuable lesson? In this childrens story, when a lonely old lady paints the leaves of the villages Rainbow Tree black, a little boy pays her a visit and helps the villagers learn the value of kindness.
The Rainbow Tree, sitting in the center of the village, has branches so large and so high that no one could see the top of the Rainbow Tree. The villagers do not know that a family of monkeys lives in the Rainbow Tree. Just like the leaves on the Rainbow Tree, each monkey is different. A very young, boy monkey named Reuben likes to ride on his mothers back, just as many baby monkeys do. His mother tells Reuben to hold on tight so that he will not fall, but Reuben wants to play with the older monkeys, even though he isnt old enough yet to jump from branch to branch. He decides to sneak away from his mother while she is asleep. Reuben jumps from one branch to another branch and then jumps againbut then he misses the tree branch and begins to fall! Can the Rainbow Tree rescue Reuben? In this childrens story, a small monkey named Reuben ignores his mother, jumps from branch to branch in the Rainbow Tree, and fallslearning a valuable lesson in the process.
Miguel is a friendly, energetic, and mischievous seven-year-old who lives in the Village of the Rainbow Tree. He has always wanted a dog. Unfortunately, his mother thinks he is too young to care for a pet. After Miguel seeks advice from an old woman in the village, she tells him it is a lot of work to feed and love a dog. After the old woman talks to his mother and receives her approval, she takes Miguel to the back of her cottage to see something. As he excitedly follows her, Miguel has no idea that just past her beautiful garden is a place where special animals live, and that there is one there just for him. Miguel and Fido: A Rainbow Tree Story shares the fun tale of a boys adventure as he adopts a special pet and learns responsibility.
The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.
The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics—now fully updated. Explains how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Helps you critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Chapters have been revised to reflect the latest clinical perspectives on drug performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field’s leading text for more than three decades, Applied Biopharmaceutics & Pharmacokinetics gets you up to speed on the basics of the discipline like no other resource. Practical problems and clinical examples with discussions are integrated within each chapter to help you apply principles to patient care and drug consultation situations. In addition, outstanding pedagogy, including chapter objectives, chapter summaries, and FAQs, plus additional application questions, identify and focus on key concepts. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics shows you how to use raw data and formulate the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination. The book also helps you work with pharmacokinetic and biopharmaceutic parameters to design and evaluate dosage regimens of drugs. In the seventh edition of this must-have interactive learning tool, most of the chapters are updated to reflect our current understanding of complex issues associated with safe and efficacious drug therapy.
A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.
This thoroughly-updated edition features contributions from more than 24 specialists, and reflects the current progress in pharmacy education and practice. Written for pharmacy students who are preparing for the NAPLEX test, and for pharmacy undergraduates and professionals who need detailed summaries of pharmacy subjects, this study guide covers chemistry, pharmaceutics, pharmacology, pharmacy practice, drug therapy, and other topics. A separate booklet of simulated NAPLEX exams supplements this review, and provides reliable test practice. Chapters are organized to parallel the pharmacy curriculum and appear in outline form for easy use. Appendices include prescription dispensing information, common prescription drugs, and general pharmacy references. It can be used by a diverse group of readers, including the following: Matriculating pharmacy students who often require such a text in their freshman year to help them prepare for course examinations / Instructors and preceptors who can use the chapter outlines to help organize courses and plan specific lectures / Professional pharmacists who can use a convenient handbook of pharmacy facts and up-to-date information
Judge Higginbotham chronicles in unrelenting detail the role of the law in the enslavement and subjugation of black Americans during the colonial period. It is a moving book that should be read by all Americans who believe in justice and dignity for all.
The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts. Features: Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development Additional chapters for this edition include: o Physiological factors related to drug absorption o Approaches to pharmacokinetics and pharmacodynamics calculations o Novel and complex dosage Forms o Clinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products o Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development Additional information on drug therapy, drug product performance, and other related topics Frequently asked questions, practice problems, clinical examples and learning questions
The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
Generic Drug Product Development: Specialty Dosage Forms explores the issues related to providing evidence of pharmaceutical equivalence and bioequivalence for specialty drug products. It describes various scientific approaches and regulatory requirements for manufacturers who need to demonstrate the therapeutic equivalence of generic specialty dru
The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics—now fully updated. Explains how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Helps you critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Chapters have been revised to reflect the latest clinical perspectives on drug performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field’s leading text for more than three decades, Applied Biopharmaceutics & Pharmacokinetics gets you up to speed on the basics of the discipline like no other resource. Practical problems and clinical examples with discussions are integrated within each chapter to help you apply principles to patient care and drug consultation situations. In addition, outstanding pedagogy, including chapter objectives, chapter summaries, and FAQs, plus additional application questions, identify and focus on key concepts. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics shows you how to use raw data and formulate the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination. The book also helps you work with pharmacokinetic and biopharmaceutic parameters to design and evaluate dosage regimens of drugs. In the seventh edition of this must-have interactive learning tool, most of the chapters are updated to reflect our current understanding of complex issues associated with safe and efficacious drug therapy.
The assessment of bioequivalence is an important process whereby the bioavailability of a generic drug product is compared with its brand-name counterpart. Generic pharmaceutical products must be approved as therapeutic equivalents to the brand name alternative in order to be interchangeable. The demonstration of bioequivalence is an important comp
This eighth edition of Comprehensive Pharmacy Review reflects the continuing evolution of pharmacy practice and educational requirements. The main objective of the book is to provide a comprehensive study guide for pharmacy students and other candidateswho are preparing for the North American Pharmacist Licensure Examination (NAPLEX). This volume represents the contributions of more than 50 specialists who provide wide expertise in pharmaceutical science, pharmacy practice, and clinical pharmacy. Theircontributions to Comprehensive Pharmacy Review assure that this review guide is accurate and current as well as written in a comprehensible manner for students, teachers, and practitioners alike. This review publication, along with the separate booklet of simulated NAPLEX exams (Comprehensive Pharmacy Review Practice Exams, 8th edition), provides both guidance and test practice for NAPLEX candidates"--Provided by publisher.
Miguel is a friendly, energetic, and mischievous seven-year-old who lives in the Village of the Rainbow Tree. He has always wanted a dog. Unfortunately, his mother thinks he is too young to care for a pet. After Miguel seeks advice from an old woman in the village, she tells him it is a lot of work to feed and love a dog. After the old woman talks to his mother and receives her approval, she takes Miguel to the back of her cottage to see something. As he excitedly follows her, Miguel has no idea that just past her beautiful garden is a place where special animals live, and that there is one there just for him. Miguel and Fido: A Rainbow Tree Story shares the fun tale of a boys adventure as he adopts a special pet and learns responsibility.
Due to a worldwide need for lower cost drug therapy, use of generic and multi-source drug products have been increasing. To meet international patent and trade agreements, the development and sale of these products must conform to national and international laws, and generic products must prove that they are of the same quality and are therapeutically equivalent to the brand name alternative. However, many countries have limited resources to inspect and verify the quality of all drug products for sale in their country. This title discusses the worldwide legislative and regulatory requirements for the registration of generic and multi-source drug products.
In a small village, there stands a very tall tree, with leaves of many different colors, shapes, and sizes. The Rainbow Trees leaves reflect the sun rays into everyones home and make the villagers happy. But nearby, in small black cottage with a big black fence and black furniture, there lives an old woman, eating black bean soup and dark pumpernickel bread. Everything is dark and gloomy for her, and she is sad and lonely, for no one in the village has visited her for more than one hundred years. One night, when no one is around, the old woman paints the leaves of the Rainbow Tree black, which makes the villagers sad and gloomy. The villagers are afraid of the old woman, but a small boy named Miguel decides to go visit her anyway. Can Miguel find a way to bring back the Rainbow Trees colorsand help the people of the village learn a valuable lesson? In this childrens story, when a lonely old lady paints the leaves of the villages Rainbow Tree black, a little boy pays her a visit and helps the villagers learn the value of kindness.
The Rainbow Tree, sitting in the center of the village, has branches so large and so high that no one could see the top of the Rainbow Tree. The villagers do not know that a family of monkeys lives in the Rainbow Tree. Just like the leaves on the Rainbow Tree, each monkey is different. A very young, boy monkey named Reuben likes to ride on his mothers back, just as many baby monkeys do. His mother tells Reuben to hold on tight so that he will not fall, but Reuben wants to play with the older monkeys, even though he isnt old enough yet to jump from branch to branch. He decides to sneak away from his mother while she is asleep. Reuben jumps from one branch to another branch and then jumps againbut then he misses the tree branch and begins to fall! Can the Rainbow Tree rescue Reuben? In this childrens story, a small monkey named Reuben ignores his mother, jumps from branch to branch in the Rainbow Tree, and fallslearning a valuable lesson in the process.
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