Is personalized medicine—what some scientists call genetic medicine—a pipe dream or a panacea? Francis Collins, current director of the National Institutes of Health and director of the Human Genome Project, considers this new era “the greatest revolution since Leonardo,” while Nobel Laureate Leland Hartwell compares personalized medicine to a train that has not yet left the station—“a very slow train with a very long way to go . . . before we arrive at our destination.” There is no denying that new technology, which has triggered an explosion of scientific information, is ushering in a revolution in medicine—for specialists, general practitioners and the public. Anyone can spit in a cup and, for a small fee, learn about his or her individual genetic make-up. But how useful is this information, really, to us or to our doctors? What’s more, how much do we truly want to know—and have others know—about our possible destiny? There is more than we can imagine at stake. In An Immense New Power to Heal, authors Lee Gutkind and Pagan Kennedy delve into the personal side of personalized medicine and offer the physician’s perspective and the patient’s experience through intimate narratives and case studies. They also offer an intriguing background of the personalized medicine movement including the fascinating personalities of the key scientists involved as well as a glimpse into the in-fighting that accompanies any race for a scientific breakthrough. The result is a highly engaging, lively, and provocative discussion about this revolution in health care, and most importantly, what it really means for patients now and in the future.
Whether examining the globalized consumption of satellite-broadcast pop music or the heroic efforts of little-known poets on the margins of the Chinese diaspora, he finds a questioning and contesting of both the Orientalist construction of a mythic monolithic China invented by the West and the Chinese obsession with ideas of authenticity and purity of nationhood.
Scouting has been called pro baseball’s personalized way of renewing itself from year to year and a pathway to the game’s past. It takes a very special person to be a baseball scout: normal family life is out of the question because travel is a constant companion. Yet for those with the genuine calling for it, there could be no other life. Hearing the special thwack off the bat that indicates a raw prospect may be the real deal is the dream that keeps true scouts going. Scouts have the difficult task of not only discovering and signing new players but envisioning the trajectory of raw talent into the future. But the place of the traditional scout has become increasingly dire. In 2016 Major League Baseball eliminated the MLB Scouting Bureau that had been created in the 1970s to augment the regular scouting staffs of individual teams. On the eve of the 2017 playoffs that saw the Houston Astros crowned as World Series champions, the team dismissed ten professional scouts and by 2019 halved the number of all their scouts to less than twenty. More and more teams are replacing their experienced talent hunters with people versed in digital video and analytics but who have limited field knowledge of the game, driven by the Moneyball-inspired trend to favor analytics, data, and algorithms over instinct and observation. In Baseball’s Endangered Species Lee Lowenfish explores in-depth how scouting has been affected by the surging use of metrics along with other changes in modern baseball business history: expansion of the Major Leagues in 1961 and 1962, the introduction of the amateur free agent draft in 1965, and the coming of Major League free agency after the 1976 season. With an approach that is part historical, biographical, and oral history, Baseball’s Endangered Species is a comprehensive look at the scouting profession and the tradition of hands-on evaluation. At a time when baseball is drenched with statistics, many of them redundant or of questionable value, Lowenfish explores through the eyes and ears of scouts the vital question of “makeup”: how a player copes with failure, baseball’s essential, painful truth.
When eighteen-year-old Charity Michaels left her hometown of Whitstokes, Michigan, twenty years ago, she never intended to return. That changes when her childhood friend, Marissa Tyson, is charged with murdering her husband, the Reverend. James Tyson II. Now an attorney, Charity feels obligated to come to Marissas defense. Charity resolves to prove Marissas innocence, especially since the body has never been found. She believes that Reverend James Tyson II, the eldest offspring of the Tyson dynasty and the heir of millions, simply abandoned his naive wife in pursuit of greener pastures. But without any tangible evidence, her supposition is like the windits stirring but invisible and therefore useless. Never one to back down from a fight, Charity searches relentlessly and eventually stumbles upon some persuasive evidence. Unfortunately, before she can expose her findings to the authorities, she makes a thoughtless decision that leaves both her and her friend vulnerable. With only forty-eight hours remaining before the final hearing, Charity scrambles to recover from her costly mistake and save Marissa.
The Wolf Within, #3 As Stanzie discovers her wolf, she learns being herself is more dangerous than ever. Where is Bethany Dillon? The seventeen year-old girl is missing from the Maplefair pack and Constance Newcastle--Stanzie--and Liam Murphy must find her. Fast. A serial killer still has not been caught. Bethany could have run away, or killed herself. But no one in her pack seems to know the truth. Or, they're just not telling. Constanceís knack for uncovering secrets leads her into peril, and to save Bethany, she must break every rule. She risks losing everything, including Liam. . .and her life. 90,135 Words
In this biography, Lee Morgan tells the story of Henry Thrale, a successful but flawed and troubled businessman and Member of Parliament who was at the center of the life of the most famous man of letters of the eighteenth century, Dr. Samuel Johnson. Thrale was also married to an exceptionally talented diarist and, perhaps, the most brilliant society leader of the period, Hester Salusbury Thrale, later Mrs. Gabriel Piozzi. In chronicling both the domestic life and the career of Thrale, Dr. Johnson's "Own Dear Master" also affords an interesting glimpse of eighteenth-century business, political, and social life of the age of Johnson as it was played out by some of the principal figures of the day.
Lee Hoyle - philosopher, man on the street or genius? Perhaps after reading this book you will make your own mind up. Unedited from his original manuscripts, this eBook contains a large number of 'mini articles' with Lee's thoughts on everything from films to planets, cranes to drugs and almost everything inbetween. This book will almost certainly reduce you to tears - some of sadness, and some of laughter. Not always factually correct, but certainly entertaining, this book is not one for the faint-hearted. Lee's writing style has been described as a cross between that of Jeremy Clarkson and Hunter S Thompson.
Alvin C. York went out on a routine patrol an ordinary, unknown American doughboy of the First World War. He came back from no-man's-land a hero. In a brief encounter on October 8, 1918, during the Argonne offensive, York had killed 25 German soldiers and, almost singlehandedly, effected the capture of 132 others. Returning to the United States the following spring, he received a tumultuous public welcome and a flood of offers from businessmen eager to capitalize on his acclaimed feat. But York, true to his character, went quietly back to his home in the Tennessee mountains, where he spent the remainder of his life working to bring schools and other services to those remote valleys where his neighbors lived. In this definitive biography, David D. Lee has firmly established the simple facts of Alvin York's life, distinguishing them from the myths which have grown up around the man. He has reexamined the sometimes conflicting accounts of the famous exploit, finding in his research a hitherto unknown report of the skirmish from German military archives. Lee goes beyond that single wartime episode, however, to consider its consequences on York's later life—his efforts, not always successful, to better his mountain community; his involvement in making a motion picture of his life; his difficulties with money and taxes. But Sergeant York is better known as a symbol than as an individual, and in this study Lee connects the man and his life to an American heroic ideal. With his rural background, his refusal to take commercial advantage of his fame, and his simple piety, Alvin York exemplified the traditional values of an agrarian America that was in his own day already receding into the past. He claimed a special place in the hearts of his countrymen, Lee concludes, because his life seemed to show that the virtues of the common man continued to be a vital part of American society.
This illustrated book - published to commemorate the centenary of the artist's death - addresses Whistler's extraordinary legacy and establishes his pivotal place in the history of American art.
Sam Bass is perhaps the most notorious Texas outlaw of the 1870s. Within four years he and his band robbed trains, stages, and stores from the Dakota Territory to the Mexican border. He was not a killer, and because the railroads and their high freight rates were unpopular, Bass quickly became a legendary hero. Nevertheless, Wells Fargo agents, railroad detectives, Texas Rangers, and posses of private citizens chased Bass from his hideout in Denton County, Texas, throughout the old Southwest until he was shot by Texas Rangers in an attempted bank robbery at Round Rock, Texas, in 1878.
It was the age of Jim Crow, riddled with racial violence and unrest. But in the world of Our Gang, black and white children happily played and made mischief together. They even had their own black and white version of the KKK, the Cluck Cluck Klams—and the public loved it. The story of race and Our Gang, or The Little Rascals, is rife with the contradictions and aspirations of the sharply conflicted, changing American society that was its theater. Exposing these connections for the first time, Julia Lee shows us how much this series, from the first silent shorts in 1922 to its television revival in the 1950s, reveals about black and white American culture—on either side of the silver screen. Behind the scenes, we find unconventional men like Hal Roach and his gag writers, whose Rascals tapped into powerful American myths about race and childhood. We meet the four black stars of the series—Ernie “Sunshine Sammy” Morrison, Allen “Farina” Hoskins, Matthew “Stymie” Beard, and Billie “Buckwheat” Thomas—the gang within the Gang, whose personal histories Lee pursues through the passing years and shifting political landscape. In their checkered lives, and in the tumultuous life of the series, we discover an unexplored story of America, the messy, multiracial nation that found in Our Gang a comic avatar, a slapstick version of democracy itself.
(Book). This ultimate guide to big bands includes hundreds of entries spanning the history of this American musical style. Each entry contains the band name, its leader, essential personnel, the years it existed, tops hits, and a brief description of the band.
Gypsy Rose Lee’s memoir became a New York Times bestseller in 1957, inspiring the 1959 hit musical, two movies, and three revivals. Now a fourth, directed by Arthur Laurents and starring Patti LuPone, is lighting up New York, winning top Broadway theatre awards, including three 2008 Tony Awards, as well as raves from critics and audiences: “No matter how long you live, you’ll never see a more exciting production.” —Terry Teachout, The Wall Street Journal “Watch out, New York! This GYPSY is a wallop-packing show of raw power.” —Ben Brantley, The New York Times “Not your ordinary theater experience. This is the best production of the best damn musical ever.” —Liz Smith, Syndicated Columnist The memoir, which Gypsy began as a series of pieces for The New Yorker, contains photographs and newspaper clippings from her personal scrapbooks and an afterword by her son, Erik Lee Preminger. At turns touching and hilarious, Gypsy describes her childhood trouping across 1920s America through her rise to stardom as The Queen of Burlesque in 1930s New York—where gin came in bathtubs, gangsters were celebrities, and Walter Winchell was king. Gypsy’s story features outrageous characters—among them Broadway’s funny girl, Fanny Brice, who schooled Gypsy in how to be a star; gangster Waxy Gordon, who fixed her teeth; and her indomitable mother, Rose, who lived by her own version of the Golden Rule: “Do unto others … before they do you.”
The eleventh edition of this classic textbook provides an overview of communication and media law that includes the most current legal developments. It explains the laws affecting the daily work of writers, broadcasters, PR practitioners, photographers and other public communicators. By providing statutes and cases in an accessible manner, even to students studying law for the first time, the authors ensure that students will acquire a firm grasp of the legal issues affecting the media. This new edition features discussions of hot topics such as the prosecution of WikiLeaks founder Julian Assange for Espionage Act violations, the U.S. Supreme Court's decision in Iancu v. Brunetti addressing the registration of offensive trademarks, revenge porn, FTC guidelines on social media influencers and efforts by social media platforms to develop coherent approaches to misinformation. The Law of Public Communication is an ideal core textbook for undergraduate and graduate courses in communication law and mass media law. A downloadable test bank is available for instructors at www.routledge.com/9780367476793.
A compelling story you won't want to miss! Well told and deeply true to its time and place." -Haywood Smith, author of Queen Bee of Mimosa Branch and The Red Hat Club Even the best-kept secrets must be revealed... Seventeen-year-old Adie Jenkins is newly married and newly pregnant, though not necessarily in that order. Unready for fatherhood, her skirt-chasing husband isn't much help. But in this stunning tale that redefines intimacy, love, and family, Adie discovers hope where she least expects it: from her sweet neighbor Murphy, from the world-wise midwife Willa Mae, and in the worn pages of the diary of a slave girl-a girl who is much closer to Adie than she thinks. Praise for Cold Rock River "An intricate novel about the mysterious ways we are all connected in the human endeavors of truth, love, longing, and loss." -Patti Callahan Henry, bestselling author of When Light Breaks "Warm, fresh, funny-the characters leap off the page! Miles is a fascinating new voice in Southern fiction. Readers will rejoice." -Karin Gillespie, author of Bet Your Bottom Dollar "Jackie Lee Miles is a wise and perceptive writer with a keen understanding of human frailties." -Julie Cannon, author of Truelove and Homegrown Tomatoes
Since his first feature movie, She's Gotta Have It (1986), gave him critical and commercial success, Spike Lee has challenged audiences with one controversial film after another. Lee has made a broad range of movies, including documentaries (4 Little Girls), musicals (School Daze), crime dramas (Clockers), biopics (Malcolm X).
Dixie Lee Brown launches her Trust No One series with this tale of a hunted woman and the only man who can save her life . . . if she'll let him. Someone wants Cara Sinclair dead. One minute she's halfheartedly enjoying an Oregon Coast casino, and the next she's being chased by hit men. Rescued by a total stranger, Cara must decide whether she can trust her safety to this Joe Reynolds and his team of ruthless mercenaries. The more time she spends with Joe, the more her desire for him grows. But can he truly protect her, or is she placing them all in mortal danger? Joe agreed to protect Cara as a promise to a dying man. He never expected to feel such heat between them, or her total lack of faith in him. Now he must convince her that her only hope lies with him. Because Joe is starting to realize that he won't be satisfied with just saving her life . . . now, he wants it all.
As the roaring twenties came to an end and a new decade dawned, the United States found itself locked in the grips of the Great Depression. The City of Detroit was no exception as industry laid off workers and bread lines formed across the city. Detroit Mayor Frank Murphy led the country in supporting state and federal welfare programs to help people through the economic crisis. By the middle of the 1930s, Detroit began picking itself up out of the economic mud and was soon flexing its industrial muscle as manufacturing, led by the auto industry, put the Motor City back into shape. As the decade ended and war approached, the city was ready to take its place on the world stage. The country reeled from the shock of the attack on Pearl Harbor and had to shift its industrial might from civilian use to the war effort. Nowhere was that more evident than in Detroit. Its huge manufacturing capabilities, when turned to the making of the implements of war, earned the city a new nickname. The Motor City became to the Arsenal of Democracy and began to evolve once more. The influx of workers from the Deep South to the war industry added yet another facet to the city's society and culture. As the Second World War came to a close and production re-tooled for the return to civilian life, an economic boom swept through Detroit. The city celebrated its 25oth birthday in 1951, prompting an outpouring of funds to build with. Major additions were made to the Art Institute, the Detroit Historical Museum, and the riverfront.
Long after the blinding flash of media attention dimmed, the town of Walkerton, Ontario was forced to deal with the aftermath of a crippling E. coli outbreak. Ranking with Eastern Ontario's great ice storm, the Walkerton water tragedy was the worst crisis of its kind in Canadian history. It resulted in death, illness, financial loss and paranoia. Don't Drink the Water: The Walkerton Tragedy details the events of this disaster; sympathizes with victims and examines what went wrong. Telling this incredible story with a creative journalistic approach, Brenda Lee Burke brings personal experience to her writing and demonstrates the strength of the Walkerton community as it pulled together in a time of great need. Don't Drink the Water includes 14 pages of exclusive Walkerton area photographs. Please visit the author's website at www.dont-drink-the-water.com
To have a son adopt his father's dream as his own is rare. But that is exactly what Rod Strong does when in 2006 he enlists in the Army to join The Old Guard. Serving as a Sentinel at the Tomb of the Unknown Soldier in Arlington Cemetery is all his father ever wants, until he dies in the Gulf War. Now Rod decides to honor his father by taking his place. He forges ahead, naively believing sheer will and hard work is all he needs. As he perseveres through Basic Training and Ranger School at Fort Benning, self-doubt begins to plague him. Still, holding firm to his father's goal, he overcomes hurdles he never anticipates. Finally he reaches the legendary 3rd U.S. Infantry Regiment at Fort Myer, the home of The Old Guard, with his goal in sight. Then an unexpected deployment to Afghanistan derails his plans and when a firefight erupts, Rod confronts an overwhelming obstacle that threatens to defeat him completely.
“A must-read for anyone who loves . . . complex and compelling coming-of-age stories, tales set in the Wild West with a tinge of magic, and/or a fast-paced read full of fae and adventure.” —Tor.com In antebellum America, two teens bury their secrets and join the historic Pony Express, soon discovering that the mortal world is not the only one on the brink of war. When bright, brash Jessamine Murphy finds a recruitment poster for the Pony Express, her tomboy heart skips a beat: not only for adventure, but for the chance to track down her wayward father in California. Eager to reunite her fractured family, Jessamine cuts her hair, dons a pair of trousers, and steps into the world as Jesse. With a bit of trickery, Jesse wins a special assignment—as does Ben Foley, a quiet but determined boy who guards secrets as closely as Jesse does. The two are to transport unusual cargo along an unusual route: the Nightland Express. They ride west together, one excitedly navigating the world as a boy, the other passing as white to escape the monsters from his past. Ben and Jesse soon realize their assignment is special in more ways than one: their tireless horses cover ground faster than should be possible, and inhuman creatures watch their journey from the darkness. The Nightland Express is more than a mail route—it traces the border between the mortal world and a vibrant, magical land just beyond. As both realms hover on the precipice of disaster, Jesse and Ben must learn to fully trust one another before a catastrophic rift separates the two worlds—and the two riders—forever.
Til Death explores the conflict that male and females experience in relationships, especially marriage. Part one examines the theological and moral aspects of male/female relationships. Part two is a love story where differing moral values clash and its consequences.
The Beast of Rickards Road appeared out of the darkness one October night and terrorized the small community of Walkertown, NC. Is it a hoax perpetrated by a person wearing a dark suite or a demon with supernatural powers on the loose in a rural farming community? In the second ghost story, the ghostly murders have been unexplained for over a century, until the sheriff's department hires a private investigator to solve the serial murders out on Payne Road. The investigator, Bill Christian meets Clara Bell and Wilber Parker, as they join forces to battle the evil demon out on Payne Road! Bill Christian goes to Old Salem to research the old records of the early Moravians to look for clues in his investigation. They must ask the Cherokee Nation for spiritual assistance because they are in for the battle of their very lives! Will the demon slayers uncover lost treasure from centuries past?
His admirers called him the "Barnum of Books" and the "Voltaire of Kansas" because of his ability to bring culture and education to the people. R. Alton Lee brings to life Emanuel Haldeman-Julius (1889-1951), a writer-publisher-entrepreneur who was one of America's most significant publishers and editorialists of the twentieth century, if not all time. His company published a record 500,000,000 copies of 2,580 titles and was second only to the U.S. Government Printing Office in the quantity of publications it produced. Lee details Haldeman-Julius's family origins in Russia and his formative years in Philadelphia, where he learned the book trade. As a writer and editor for the Social Democrat, Sunday Call, and Western Comrade, Haldeman-Julius was already well known by the time he launched his own publishing company. Haldeman-Julius knew, was nurtured by, and published writers such as Jack London, Upton Sinclair, Jane Addams, Emma Goldman, H. L. Mencken, Carl Sandburg, Eugene V. Debs, Clarence Darrow, Job Harriman, Will Durant, and Bertrand Russell, among others. Based in Girard, Kansas, his company, Haldeman-Julius Publications, covered socialist politics, the philosophy of free thought, and both new and classic books marketed to ordinary Americans, including the Little Blue Book series of classics in Western thought and literature. This biography of the enigmatic and energetic Haldeman-Julius opens a window into the fascinating world of early twentieth-century radical politics and publishing"--
God's astounding claims about himself and his work on our behalf are embedded throughout the pages of Scripture. He sees potential in us that we don't see in our wildest dreams. He sees qualities that we don't think we can ever achieve. He has faith in us that we lack in ourselves. But when we know and fully understand what He has promised, we are liberated to grow in virtue, live out our faith as an adventure, relate to others with authenticity, earn a living with integrity, and make a difference in our culture--all through his power. Lee Strobel's insights into the benefits of living as a fully devoted follower of Christ are refreshing and powerfully relevant. Using true stories, including his own, he shows that Christianity really works, that we really can live transformed, authentic, and effective lives--and that God's promises and power are very real and very true.
As seen on ITV's This Morning 'You really can learn to talk to your pet' - Daily Mail We all want what's best for our pets, but what if we simply don't understand what that is? With this easy introductory guide to animal communication, you can leave out the guesswork and open yourself to a deeper, richer relationship with your pet. In this book, you will: • Learn exactly what animal communication is, how it differs from being a pet psychic and the different types of ways you can psychically communicate with your pet, including Beth's unique PACT method • Receive important messages from your pet, learn to communicate with other people's pets, as well as read messages via photographs • Understand how to solve behavioural issues in your pet and help them with their wellbeing • Be able to learn how to use animal communication to help cope with the loss of a beloved pet as well as learn how to use your new skills to locate a missing animal. Your pet is part of your family, they know what you are feeling, and now you can really understand what they are feeling too.
Judy leads what appears to be the perfect teen life. She is a vivacious, intelligent, active girl. She loves her horses, her barrel riding, her BFF Helen and adores her adoptive father. But she is hiding a not so well kept secret. Her adoptive mother has mental issues that are a threat to Judy. Her adoptive father is convinced that if she and her adoptive mother spend enough time together they will develop a mother daughter relationship. A small network of protectors try to keep her safe but know it is a situation that could turn into serious situation at any moment. Judy may not survive Her mothers abusive rants and her unpredictable assaults. One last explosive violent act changes life for everyone concerned.
Dr. Lee P. Brown, one of America's most significant and respected law enforcement practitioners, has harnessed his thirty years of experiences in police work and authored Policing in the 21st Century: Community Policing. Written for students, members of the police community, academicians, elected officials and members of the public, this work comes from the perspective of an individual who devoted his life to law enforcement. Dr. Brown began his career as a beat patrolmen who through hard work, diligence and continued education became the senior law enforcement official in three of this nation's largest cities. The book is about Community Policing, the policing style for America in the Twenty-First Century. It not only describes the concept in great detail, but it also illuminates how it evolved, and how it is being implemented in various communities throughout America. There is no other law enforcement official or academician who is as capable as Dr. Brown of masterfully presenting the concept of Community Policing, which he pioneered. As a philosophy, Community Policing encourages law enforcement officials, and the people they are sworn to serve, to cooperatively address issues such as crime, community growth, and societal development. It calls for mutual respect and understanding between the police and the community. The book is written from the perspective of someone whose peers identify as the "father" of Community Policing, and who personally implemented it in Police Departments under his command. It is a thoroughly amazing book that has been heralded as a "must read" for anyone who has an interest in law enforcement. Elected officials, academicians, leaders of the nation's police agencies and members of the public will be captivated by Dr. Brown's literary contribution.
Life Ain't Over Yet is Lee Heide's 20-piece collection of short stories about seniors. Dramatic, humourous, and always well-written, Heide's stories are at once touching, powerful and meaningful.
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