Business development transactions are an important way for private and small cap life science companies to realize value. When negotiating transaction terms, small companies confront a playing field tilted steeply to the advantage of large companies such as Pfizer, GSK, J&J, and Medtronic. Leveling the Playing Field shows how small companies can create a level playing field and achieve a transaction that fully recognizes the value of their technologies and products. Leveling the Playing Field uses auctions as a model for successful business development. Auctions are especially effective in creating power for sellers when many, wealthy bidders compete enthusiastically to acquire a singular asset, a Rembrandt painting, a uniquely situated piece of real estate, a small company's technology or product. Leveling the Playing Field guides small companies through the process of attracting large companies, transforming their interest into enthusiasm, and maintaining a high level of competition among potential buyers for as long as possible. Leveling the Playing Field draws on the authors' experiences closing more than 100 transactions ranging in size from a few million to over $2 billion as well as their serving as senior finance, R&D, and operations executives with large and small life science companies.
Old South Brooklyn Entrepreneur is far more than a financial and commercial biography of Anson Blake 1789-1868. It provides many details of local history, not only of South Brooklyn (today’s Cobble Hill, Carroll Gardens, Red Hook, Boerum Hill and Gowanus) before the Civil War, but of New York City’s economic history, including Anson Blake’s speculation in Wall Street area lands and buildings. Blake also speculated in Upstate New York’s Black River Canal region of Oneida, Hamilton and Herkimer counties where Anson Blake wanted a railroad to be built through his lots. Many interesting illustrations and photographs depict facets of Manhattan and Brooklyn history — including Blake’s early land and building speculation enterprises in South Brooklyn adjacent to the terminus of the original Long Island Railroad, and the Atlantic Street and Hamilton Avenue ferries. This book describes New York’s and Brooklyn’s history during the second quarter of America’s 19th century.
The latest edition of Pediatric Dermatology, edited by Lawrence A. Schachner, MD and Ronald C. Hansen, MD brings you the detailed guidance you need to effectively diagnose and treat pediatric skin conditions. Review topics from keratinization to stem cell therapy, and gain expert guidance from international contributors. - Refer to full-color photographs that accurately capture the appearance of a wide range of skin disorders. - Access many new tables and therapeutic algorithms for at-a-glance guidance. - Easily access the full text online plus a downloadable image library at www.expertconsult.com. - Recognize distinguishing factors in skin lesions with 40% new and improved clinical photographs. - Find extended coverage of topics like genodermatoses and disorders of keratinization, review excellent information on skin neoplasms in children, new systemic therapies, and viral disorders, and explore new concepts in autoinflammatory disorders and Kawasaki's disease. - Read up on best practices and stay at the forefront of your profession with new perspectives from a host of international contributors like new Associate Editor Antonio Torrello, who co-edits the Pediatric Dermatology journal.
Now in its 10th edition, Sleisenger and Fordtran?s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments?with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos. "..one of the most valuable clinical resources in the dynamic field of gastroenterology and hepatology." Reviewed by Brindusa Diaconu on behalf of the Journal of Gastrointestinal and Liver Diseases, July 2015 "..an engaging, educational yet clinically orientated textbook which is relevant to modern clinical practice." Reviewed by Dr Harry Brown on behalf of glycosmedia.com, April 2015 "I can personally attest to the remarkable advances that have been made, as I was author of the chapter on eosinophilic gastroenteritis in the second edition of the textbook, and reading the same chapter in the tenth edition underscores the important advances that have been made in our understanding of the molecular basis as well as the pathophysiology of this and related disorders." Foreword by Norton J. Greenberger, MD Boston, Massachusetts, June 2015 Consult this title on your favorite e-reader. Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
This volume contains abstracts of all papers presented at the International Echinoderms Conferences, and complete papers of those which were submitted for publication and accepted upon recommendation of referees.
For every astronomical topic that I have approached there has turned out to be a broader realm of possibilities than is commonly accepted or acknowledged. The "excursions" of this book are the examples. They mostly depart from the mainstream of conventional wisdom to offer a wider perspective with opportunities for further research. While my intent is to supplement that mainstream, the effect may appear to dismiss rather than to reconsider accepted tenets. Ample praise and credit for those accomplishments are already available in textbooks. Readers may very well disagree with some of the notions presented in these excursions, but I hope that they will pause long enough to evaluate the scientific basis for any disagreement. For the most part, these excursions remain incomplete and unfulfilled, yet they contain many ideas that are not available elsewhere. Whether these ideas are per ceived as a collection of unproven claims or as a storehouse of fresh opportunities will depend entirely on the attitude of the reader. The excursions do cover a rather wide span of disciplines, and that may lead to an unfocused overall impression. My hope is thereby to attract a broader audience than that of a single discipline, and to expose them to neighboring disciplines. The excursions all do have the common thread of optical science related to astronomy.
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