Many friends, colleagues, and research staff members have directly and indirectly contributed to this book. It is impossible to acknowledge the contribution of each. Still, we would like to recognize several persons as well as institutions that have been particularly helpful. Research funds were provided by the Kentucky Agricultural Experiment Station and by the Ford Foundation. John Myers of the Current Research Information System provided us with a computer tape listing current projects. Carolyn Sachs was extremely helpful in coordinating the mail survey of scientists. Christian Ritter, Lisa Slatin, and Bobbie Sparks assisted in coding the data. Ann Stockham developed the index and also organized the data. Janet Baynham, Sue Lewis, and Greg Taylor aided in the voluminous computer programming and statistical analysis. Rosemary Cheek typed most of the manuscript. Marlene Pettit, Michael Claycomb, Deborah Wheeler, and Penny Hogue also assisted in the typing. Janice Taylor aided in the manuscript typing and ran interference on much of the administrative detail.
The State Agricultural Experiment Stations have played a fundamental role in the development of science and agriculture in the United States. From their inception in 1887, the experiment stations have attempted to wed basic research with practical application and have helped institutionalize a utilitarian approach to agricultural science. Agricultural research and the new technology it helped to generate were major factors in the transformation of U.S. agriculture into a high technology, mechanized, science-based industry. Moreover, the experiment stations, as the first large-scale, publicly supported scientific research institutions in the United States, have also long been models for scientific institutions both here and abroad. Compiled for the 1987 centennial of the State Agricultural Experiment Stations, this volume critically examines past performance, current issues, and future directions for public agricultural research in the United States. Each of the authors, drawn from disciplines as diverse as philosophy and agronomy, focuses on a central concern for the scientific enterprise. Issues include priority setting, maintaining and promoting disciplinary and interdisciplinary effectiveness, supporting higher education for agriculture, and efficacious dissemination of research findings. By setting these issues in their historical and philosophical context, the volume suggests new approaches for meeting the continuing challenge to achieve equity, efficiency, sustainability, flexibility, conservation, and consistency with other objectives of U.S. society.
Despite the fact that every year it produces a larger surplus of agricultural products than any other country in the world, the U.S. still must contend with a number of important but often unaddressed issues related to food security, including problems of soil erosion, water supply, energy availability, nutrition; farm worker health and safety, and product distribution. This book; containing contributions from authorities in both the natural and social sciences, expands the range of issues pertinent to the security of the U.S. food system, taking into account the adequacy and sustainability of the food supply, equity in access to food by the entire population, the nutritional quality of food, and the costs and benefits (social, economic, and health) of the food system as it is presently organized. Each of the authors considers an aspect of U.S. food security from the point of view of a specific discipline, as well as in terms of broader policy implications.
It is known that the plan to elect a Prussian prince to the Spanish throne was the proximate, and Bismarck’s “Ems telegram” an immediate cause of the war of 1870. But much has remained obscure about the roles of the principal figures. Lawrence Steefel fills in the lacunae with secret German documents available only after World War II, including the correspondence between Bismarck and Marshal Prim of Spain. It becomes clear that Bismarck did not initiate the Hohenzollern candidacy and that one of his most important reasons for adopting it was his fear of an anti-Prussian coalition of Catholic powers.
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. - Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats - Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace - Each chapter will include a map of the world showing where that particular disease is naturally found
Why should the gene be suggested to be inconstant when the contrary view, that gene structure is invariant except through mutagenic processes induced by potent external factors, has long been a universal doctrine of genetics? Indeed, during the early part of the present century before mutation was recognized as being of general occurrence, the seeming unvarying nature of the gene led to skepticism regarding the validity of the evolutionary theory; only later could the origins of the morphological differences between individuals and species be attributed to a combination of mutation and evolution, involving natural forces selecting between favorable and unfavorable genetic changes. But during the past several decades, as knowledge of the macromolecular constitution of or ganisms has increased to the point where even the primary structures of the genes themselves are being revealed on a routine basis, it has become increas ingly difficult to ascribe all the resulting observations to ordinary mutagenesis and natural selection. Some more profound mechanism often seems to be present that influences both the constancy and inconstancy of the genes, an ap paratus whose existence this study hopes to reveal. In seeking to demonstrate the universality of this mechanism, data are sought through the numerous activities of organisms of many types wherever gene action changes are manifest.
This issue of Surgical Oncology Clinics of North America, edited by Dr. Lawrence Wagman, is devoted to Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver. Articles in this issue include: Epidemiology of Hepatomas; Risk Modeling: disease prevalence, outcome from treatment; Imaging; Resection techniques; Ablation techniques; Complications of interventions; Trans-arterial chemo-embolization (TACE); Continuous hepatic artery infusion (CHAI); Selective interstitial radiation therapy (SIRT) and External beam radiation therapy (EBRT); Systemic chemotherapy of HCC and Cholangiocarcinoma; and Systemic chemotherapy and CRC metastases.
This volume contains Lawrence's letters written between March 1927 and November 1928: almost 770 letters in just a year and nine months. The letters cover the period of Lawrence's Etruscan tour in the spring of 1927 as preparation for the writing of Sketches of Etruscan Places; the performance of his play, David, in London in May, and - above all - the writing, typing, private publication, promotion and immediate consequences of Lady Chatterley's Lover. He makes new acquaintances with writers and publishers in Europe (Max Mohr, Hans Carossa, Harry and Caresse Crosby); renews friendships which will stand him in good stead in times of poor health (the Huxleys, Aldington, the Brewsters); and rediscovers the bonds of family and old Eastwood friends. The volume provides annotation identifying persons and allusions, and includes a biographical introduction, illustrations, a full chronology and index.
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