This book thoroughly covers the development of the theory of rotating hydraulics, making frequent use of supporting laboratory models and observational data. The need to understand rotating hydraulic phenomena is growing as general interest in climate and global circulation is continuously increasing. The book details cutting-edge research and includes many exercises.
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. - Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats - Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace - Each chapter will include a map of the world showing where that particular disease is naturally found
An understanding of statistical thermodynamic molecular theory is fundamental to the appreciation of molecular solutions. This complex subject has been simplified by the authors with down-to-earth presentations of molecular theory. Using the potential distribution theorem (PDT) as the basis, the text provides a discussion of practical theories in conjunction with simulation results. The authors discuss the field in a concise and simple manner, illustrating the text with useful models of solution thermodynamics and numerous exercises. Modern quasi-chemical theories that permit statistical thermodynamic properties to be studied on the basis of electronic structure calculations are given extended development, as is the testing of those theoretical results with ab initio molecular dynamics simulations. The book is intended for students taking up research problems of molecular science in chemistry, chemical engineering, biochemistry, pharmaceutical chemistry, nanotechnology and biotechnology.
Are you a student or resident taking a gastroenterology rotation, a fellow in gastroenterology training, or a practitioner approaching GI recertification? Do you need a rapid-reference, essential guide to help refresh your clinical knowledge? Essentials of Gastroenterology provides students, residents, and gastroenterologists, especially those in training, with a highly practical, concise guide to the GI system and its major diseases. Full color throughout, the book covers all conditions encountered during GI training and education programs and in the clinical setting. With a strong focus on the clinical aspects of GI disease, it highlights the specific scenarios you will be presented with when managing your patients on the wards. Each section looks at a particular area of the GI tract, with each disease-related chapter examining the following: overview of normal function physiology and pathophysiology clinical presentation differential diagnosis diagnostic tests treatment/management options In addition, there is a section dedicated to the most common symptoms that patients present with, as well as a picture gallery of common GI conditions such as peptic ulcers and inflammatory bowel disease. Drs. Sitaraman and Friedman have ensured that the key emphasis throughout is on providing easy-to-assimilate, rapid-reference information on each GI condition, achieved through the use of color-coded text features such as key facts, potential pitfalls, and practice tips. Packed with multiple choice questions and specific clinical case studies, the book also draws upon the guidelines and recommendations of the world’s leading gastroenterology societies – the AGA, ASGE, ACG, BSG, WGO, and UEGF.
While surveys show that most of us would prefer to die at home, 80% of us will die in a health care facility, many hooked up to machines and faced with tough decisions. When you, a family member, or a friend are in this situation, what should you do next? In Embracing Our Mortality, Dr. Lawrence J. Schneiderman, a physician who is our leading expert on medical ethics at the end of life, urges all of us, including health care professionals caring for people at the end of life, to face these decisions with sensitivity and realism informed by both the latest medical evidence as well as the oldest humanistic visions. Dr. Schneiderman vividly demonstrates the wisdom of this approach by interweaving true stories of his patients, current empirical research in care at the end of life, displays of the power of empathy and imagination as embodied in the work of writers like Tolstoy and Chekov, and examples of how the distortion of medical research by media, and its misunderstanding even by health care professionals, cloud the ability to think, feel, and decide clearly about mortal concerns. He ends by addressing the question implicit in all of this which is how to achieve a just and universal health care. Dr. Schneiderman proves a refreshingly honest, astringent, and life-affirming guide to thinking about the choices that we or people we love will face when we dienot if, as the technological imperatives of modern medicine can suggestand to making decisions at the end of life that respect all that has preceded it.
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues
Modern Surgical Pathology, 2nd Edition presents today's most complete, current, and practical assistance in evaluating and signing out surgical specimens. Nearly 3,000 high-quality color pathology images provide a crystal-clear basis for comparison to any sample you see under the microscope. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are integrated as appropriate for all tumors and tumor-like lesions, addressing all of the investigative contexts relevant to formulating an accurate diagnosis. Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. Weiss, MD - with contributions from more than 70 other experts, Modern Surgical Pathology, 2nd Edition delivers the well-rounded, well-organized, richly illustrated, user-friendly guidance you need to efficiently arrive at confident diagnoses for even the most challenging lesions. Contributions from many leading surgical pathologists give you well-rounded, expert answers to any question that you may face. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are correlated as appropriate for every type of surgical pathology specimen, addressing all of the investigative contexts relevant to formulating an accurate diagnosis and thereby ensuring a completely accurate surgical report. Nearly 3,000 brand-new, high-quality color pathology images provide a crystal-clear basis for comparison to any specimen you see under the microscope. A completely rewritten section on the female reproductive tract offers many more illustrations of common entities to help you more easily distinguish between tumors and tumor-like lesions. Expanded coverage of non-neoplastic diseases and disorders makes it easier to recognize benign conditions that can mimic malignancy. The latest classification schemes and criteria for malignancy, incorporated throughout, enable you to include the most current gradings in your reports. A new, more consistent organization explores anatomy/histology, gross and microscopic appearance, adjunct techniques, diagnosis, and differential diagnosis for each neoplastic or non-neoplastic lesion, facilitating rapid consultation in the reporting room. An increased number of differential diagnosis and classification tables expedite diagnosis.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more.
The standard-setting text in oncology for 40 years, DeVita, Hellman and Rosenberg’s Cancer: Principles and Practice of Oncology, 12th Edition, provides authoritative guidance and strategies for managing every type of cancer by stage and presentation. Drs. Vincent T. DeVita, Jr., Theodore S. Lawrence, and Steven A. Rosenberg oversee an outstanding team of expert contributing authors who keep you up to date and fully informed in this fast-changing field. This award-winning reference is also continually updated on Health Library and VitalSource platforms for the life of the edition.
This student-friendly introductory core text describes the criminal justice process in the United States — outlining the decisions, practices, people, and issues involved. It provides a solid introduction to the mechanisms of the criminal justice system, with balanced coverage of the issues presented by each facet of the process, including a thorough review of practices and controversies in law enforcement, the criminal courts, and corrections. * Each chapter is enhanced by important terms, boxes, photos, and review questions * New edition includes updated statistics and an extended focus on theoretical approaches throughout the text * New information and attention added on terrorism and homeland security issues * An easy-to-access glossary offers a complete collection of essential terms in criminal justice
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Lymphomas and Leukemias: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a complete and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of leukemias and lymphomas. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on leukemias and lymphomas drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the full range of adult lymphomas and leukemias, including the molecular biology of lymphomas and acute and chronic leukemias; Hodgkin’s lymphoma; non-Hodgkin’s lymphoma; cutaneous lymphomas; management of acute and chronic leukemias, future directions and new treatments; myelodysplastic syndromes; plasma cell neoplasms; and more. Includes comprehensive information on leukemias and lymphomas of childhood, including supportive, long-term, palliative, and hospice care. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy apply to leukemias and lymphomas. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
This text, now in its second edition, offers an up-to-date, expanded treatment of the behaviour of polymers with regard to material variables and test and use conditions. It highlights general principles, useful empirical rules and practical equations.;Detailing the specific behaviour of many common polymers, the text: places emphasis on time and frequency dependence over temperature dependence; uses contemporary molecular mechanisms to explain creep, stress relaxation, constant strain rate responses and crazing; provides explicit equations to predict responses; supplies a discussion of large deformation multiaxial responses; compares statistical and continuum theories on the same data set; and updates stress-strain behaviour and particulate filled systems.
Understand and apply the scientific advances that are revolutionizing cancer research and practice with Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely hailed as the definitive clinical reference in oncology – the second editon of this popular Primer focuses on the molecular biology information that is of critical importance to research scientists and clinical oncologists alike. Get up-to-date, dependable coverage of every important frontier in aspect of the molecular biology of cancer with contributions from a noteworthy roster of leading scientists and clinicians, featuring an updated version of the classic “Hallmarks of Cancer” by Hanahan and Weinberg See how molecular biology advances are impacting clinical practice with separate chapters on each of the 19 most common cancer types. Navigate the challenges and ethical dilemmas of cancer genetics with a thorough section chapters on genetic counseling and genetic testing.
Reflecting recent re-examinations of the nature and purpose of the modern publicly held corporation, Progressive Corporate Law introduces the reader to alternative perspectives within the field. The contributors to this volume are loosely bound both by their rejection of the prevailing paradigm of the corporation as a public good designed exclusively for the maximization of private profit and by their affirmative goal of designing corporate laws that accord better with the corporation's political and social realities. The resulting series of visions emphasizes communitarian themes of efficiency and morality of responsibility, altruism, and unity within the corporate form as well as between the corporation and the broader society. Progressive Corporate Law is important reading for business executives, lawyers, policymakers, and others who are concerned with the role of corporations in modem life. Designed to act as a springboard for stimulating discussion, it will be a valuable supplement to courses and seminars in corporate law and business ethics.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Cancer of the Skin: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of skin cancers. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on cancer of the skin drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the full range of skin cancers, including nonmelanoma skin cancer, actinic keratosis, basal cell carcinoma, squamous cell carcinoma, angiosarcoma, microcystic adnexal carcinoma, and more; as well as cutaneous melanoma, including molecular biology; and genetic testing in skin cancer. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy applies to skin cancer. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
This student-friendly introductory text describes the criminal justice process—outlining the decisions, practices, people, and issues involved. It provides a solid introduction to the mechanisms of the criminal justice system, with balanced coverage of the issues presented by each facet of the process, including a thorough review of practices and controversies in law enforcement, the criminal courts, and corrections.
Why should the gene be suggested to be inconstant when the contrary view, that gene structure is invariant except through mutagenic processes induced by potent external factors, has long been a universal doctrine of genetics? Indeed, during the early part of the present century before mutation was recognized as being of general occurrence, the seeming unvarying nature of the gene led to skepticism regarding the validity of the evolutionary theory; only later could the origins of the morphological differences between individuals and species be attributed to a combination of mutation and evolution, involving natural forces selecting between favorable and unfavorable genetic changes. But during the past several decades, as knowledge of the macromolecular constitution of or ganisms has increased to the point where even the primary structures of the genes themselves are being revealed on a routine basis, it has become increas ingly difficult to ascribe all the resulting observations to ordinary mutagenesis and natural selection. Some more profound mechanism often seems to be present that influences both the constancy and inconstancy of the genes, an ap paratus whose existence this study hopes to reveal. In seeking to demonstrate the universality of this mechanism, data are sought through the numerous activities of organisms of many types wherever gene action changes are manifest.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Cancer of the Breast: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of breast cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Colon and Other Gastrointestinal Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of colon and GI cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Lake Michigan, winding creeks, sprawling swamps, and one of the world’s great rivers--Illinois’s variety of aquatic habitats makes the Prairie State home to a diverse array of fishes. The first book of its kind in over forty years, An Atlas of Illinois Fishes is a combination of nature guide and natural history. It provides readers with an authoritative resource based on the extensive biological data collected by scientists since the mid-1850s. Each of the entries on Illinois’s 217 current and extirpated fish species offers one or more color photographs; maps depicting distributions at three time periods; descriptions of identifying features; notes on habitat preference; and comments on distribution. In addition, the authors provide a pictorial key for identifying Illinois fishes. Scientifically up-to-date and illustrated with over 240 color photos, An Atlas of Illinois Fishes is a benchmark in the study of Illinois’s ever-changing fish communities and the habitats that support them.
Based on deep consultation of seldom-examined primary sources, this third volume in Richard Lawrence Miller's massive Lincoln biography follows Lincoln's long effort to win a seat in Congress, his activity there, and his return to Illinois--chastened by his Washington experience. Topics include: Lincoln's anti-slavery efforts in Congress; the popularity of his stance against the Mexican War (which, contrary to common belief, didn't significantly harm his political reputation); his support of Zachary Taylor's presidential campaign and his subsequent efforts to win a patronage job from the Taylor White House; his political activities after returning to Illinois; and his generally happy home life with Mary and his sons. Throughout the work, a new portrait emerges of Lincoln as a canny politician, making his own luck by striking swiftly and strongly when opportunities arose.
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