The third Earl of Shaftesbury was a pivotal figure in eighteenth-century thought and culture. Professor Klein's study is the first to examine the extensive Shaftesbury manuscripts and offer an interpretation of his diverse writings as an attempt to comprehend contemporary society and politics and, in particular, to offer a legitimation for the new Whig political order established after 1688. As the focus of Shaftesbury's thinking was the idea of politeness, this study involves the first serious examination of the importance of the idea of politeness in the eighteenth century for thinking about society and culture and organising cultural practices. Through politeness, Shaftesbury conceptualised a new kind of public and critical culture for Britain and Europe, and greatly influenced the philosophical and cultural models associated with the European Enlightenment.
Are Supreme Court justices swayed by the political environment that surrounds them? Most people think "yes," and they point to the influence of the general public and the other branches of government on the Court. It is not that simple, however. As the eminent law and politics scholars Neal Devins and Lawrence Baum show in The Company They Keep, justices today are reacting far more to subtle social forces in their own elite legal world than to pressure from the other branches of government or mass public opinion. In particular, the authors draw from social psychology research to show why Justices are apt to follow the lead of the elite social networks that they are a part of. The evidence is strong: Justices take cues primarily from the people who are closest to them and whose approval they care most about: political, social, and professional elites. In an era of strong partisan polarization, elite social networks are largely bifurcated by partisan and ideological loyalties, and the Justices reflect that division. The result is a Court in which the Justices' ideological stances reflect the dominant views in the appointing president's party. Justices such as Clarence Thomas and Ruth Bader Ginsburg live largely in a milieu populated by like-minded elites. Today's partisanship on the Court also stems from the emergence of conservative legal networks such as the Federalist Society, that reinforce the conservative leanings of Republican appointees. For the Warren and Burger Courts, elite social networks were dominated by liberal elites and not divided by political party or ideology. A fascinating examination of the factors that shape decision-making, The Company They Keep will reshape our understanding of how political polarization occurs on the contemporary Supreme Court.
The Pacific Symposium on Biocomputing (PSB) 2009 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2009 will be held on January 59, 2009 in Kamuela, Hawaii. Tutorials will be offered prior to the start of the conference. PSB 2009 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
The Supreme Court, Twelfth Edition, examines all major aspects of the highest court in the nation, from the selection of justices and agenda creation to the decision-making process and the Court’s impact on government and U.S. society. Delving deeply into personalities and procedures, author Lawrence Baum provides a balanced explanation of the Court’s actions and the behavior of its justices as he reveals its complexity, reach, and influence. This new edition gives particular attention to current developments such as the impact of political polarization on the Court, the justices’ increasingly public roles, and recent rulings on same-sex marriage and health care.
The Pacific Symposium on Biocomputing (PSB 2003) is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. The rigorously peer-reviewed papers and presentations are collected in this archival proceedings volume. PSB 2003 brings together top researchers from the US, the Asia-Pacific region and around the world to exchange research findings and address open issues in all aspects of computational biology. PSB is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues
The Pacific Symposium on Biocomputing brings together key researchers from the international biocomputing community. It is designed to be maximally responsive to the need for critical mass in subdisciplines within biocomputing. This book contains peer-reviewed articles in computational biology.
The Pacific Symposium on Biocomputing (PSB 2005) is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. This latest volume in the prestigious conference series contains the contributions of top researchers from the US, the Asia-Pacific region and around the world. Sections are devoted to databases, algorithms, interfaces, visualization, modeling and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The book is an essential source of ideas, discoveries and references for academics in biocomputing, bioinformatics researchers and computer scientists.The proceedings have been selected for coverage in: ? Biochemistry & Biophysics Citation Index(tm)? Index to Scientific & Technical Proceedings? (ISTP? / ISI Proceedings)? Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings)? CC Proceedings ? Biomedical, Biological & Agricultural Sciences
Conquest and Reconquest, Liberation and Restoration of Christendom in the Frontiers of Arago-Catalunya: Volume I: History Remembered, Revisited and Retold: Interpretations across the Millennia
Conquest and Reconquest, Liberation and Restoration of Christendom in the Frontiers of Arago-Catalunya: Volume I: History Remembered, Revisited and Retold: Interpretations across the Millennia
This extensive bibliographic essay underpins the entire Tarragona Vortex study by focusing on this arena as one of the most contested frontiers in Western history, comparable to Jerusalem in the East, for broad issues of Romanization, Westernization, Islamization, and Christianization. Its book length chapters treat (1) diverse historiographies from local and Spanish to comparative Mediterranean and Crusade History, and especially Ethno-historiography and the explanatory concept of frontiers; (2) the phenomena of religion conversion and reform, and the conditioning agents of Islam and Latin Christianity in practice and adversity; (3) religious universalism and violence, especially religious war; (4) the Crusade and Reconquest paradigms and century-long debate; (5) the environment on land and sea, and setting for this History. Although these themes are explored to include due reconsideration but avoid major digressions in its telling about Tarragona and the Tarraconensis, they underly so much of Late-Antique and Medieval historical research that this discussion pertains to the whole field of historical, cultural, and religious studies.
Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to research scientists interested in the study of cancer and to oncologists who need to understand these new developments that are having a profound impact on the care of patients with cancer. Leading scientists and clinicians in the field of molecular biology and clinical oncology have lent their expertise to this project. The text has been divided into two parts. Part I includes thirteen chapters that deal with the general principles of the molecular biology of cancer that provide the basic framework for an understanding of the behavior of cancer cells. Part II includes an up-to-date description of how this new information has affected the understanding of the biology of 19 of the most common cancers, with an emphasis on how these new findings have been translated to impact the management of cancer patients. This distinctive text provides a single concise source of information for scientists and clinicians in this rapidly developing field
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. - Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats - Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace - Each chapter will include a map of the world showing where that particular disease is naturally found
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Understand and apply the scientific advances that are revolutionizing cancer research and practice with Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely hailed as the definitive clinical reference in oncology – the second editon of this popular Primer focuses on the molecular biology information that is of critical importance to research scientists and clinical oncologists alike. Get up-to-date, dependable coverage of every important frontier in aspect of the molecular biology of cancer with contributions from a noteworthy roster of leading scientists and clinicians, featuring an updated version of the classic “Hallmarks of Cancer” by Hanahan and Weinberg See how molecular biology advances are impacting clinical practice with separate chapters on each of the 19 most common cancer types. Navigate the challenges and ethical dilemmas of cancer genetics with a thorough section chapters on genetic counseling and genetic testing.
Acknowledging that though the disciplines are supposed to be cumulative, there is little in the way of accumulated, general theory, this work opens a dialogue about the appropriate means and ends of social research based in analysis of fundamental issues. This book examines two root issues in the methodology of explanatory social research--the meaning of the idea of causation in social science and the question of the physiological mechanism that generates intentional behavior. Conclusions on these as well as on several derived problems emerge through the analysis. Among the latter, the analysis shows that neither universal nor probabilistic laws governing human behavior are possible, even within the positivist or empiricist traditions in which laws are a central feature. Instead, the analysis reveals a more modest view of what an explanatory social theory can be and do. In this view, the kind of theory that can be produced is basically the same in form and content across quantitative and qualitative research approaches, and similarly across different disciplines. The two streams of analysis are combined with resulting implications for large-sample, small-sample, and case study research design as well as for laws and theory. Written for the practicing empirical researcher in political science and organization theory, whether quantitative or qualitative, the major issuesand findings are meant to hold identically, however, for history, sociology, and other social science disciplines. Lawrence B. Mohr is Professor of Political Science and Public Policy, University of Michigan.
What motivates judges as decision makers? Political scientist Lawrence Baum offers a new perspective on this crucial question, a perspective based on judges' interest in the approval of audiences important to them. The conventional scholarly wisdom holds that judges on higher courts seek only to make good law, good policy, or both. In these theories, judges are influenced by other people only in limited ways, in consequence of their legal and policy goals. In contrast, Baum argues that the influence of judges' audiences is pervasive. This influence derives from judges' interest in popularity and respect, a motivation central to most people. Judges care about the regard of audiences because they like that regard in itself, not just as a means to other ends. Judges and Their Audiences uses research in social psychology to make the case that audiences shape judges' choices in substantial ways. Drawing on a broad range of scholarship on judicial decision-making and an array of empirical evidence, the book then analyzes the potential and actual impact of several audiences, including the public, other branches of government, court colleagues, the legal profession, and judges' social peers. Engagingly written, this book provides a deeper understanding of key issues concerning judicial behavior on which scholars disagree, identifies aspects of judicial behavior that diverge from the assumptions of existing models, and shows how those models can be strengthened.
This is the history of temperance and prohibition as you've never read it before: redefining temperance as a progressive, global, pro-justice movement that affected virtually every significant world leader from the eighteenth through early twentieth centuries. When most people think of the prohibition era, they think of speakeasies, rum runners, and backwoods fundamentalists railing about the ills of strong drink. In other words, in the popular imagination, it is a peculiarly American history. Yet, as Mark Lawrence Schrad shows in Smashing the Liquor Machine, the conventional scholarship on prohibition is extremely misleading for a simple reason: American prohibition was just one piece of a global phenomenon. Schrad's pathbreaking history of prohibition looks at the anti-alcohol movement around the globe through the experiences of pro-temperance leaders like Vladimir Lenin, Leo Tolstoy, Thomás Masaryk, Kemal Atatürk, Mahatma Gandhi, and anti-colonial activists across Europe, Asia, Africa, and the Middle East. Schrad argues that temperance wasn't "American exceptionalism" at all, but rather one of the most broad-based and successful transnational social movements of the modern era. In fact, Schrad offers a fundamental re-appraisal of this colorful era to reveal that temperance forces frequently aligned with progressivism, social justice, liberal self-determination, democratic socialism, labor rights, women's rights, and indigenous rights. Placing the temperance movement in a deep global context, forces us to fundamentally rethink its role in opposing colonial exploitation throughout American history as well. Prohibitionism united Native American chiefs like Little Turtle and Black Hawk; African-American leaders Frederick Douglass, Ida Wells, and Booker T. Washington; suffragists Elizabeth Cady Stanton, Susan B. Anthony, and Frances Willard; progressives from William Lloyd Garrison to William Jennings Bryan; writers F.E.W. Harper and Upton Sinclair, and even American presidents from Thomas Jefferson and Abraham Lincoln to Theodore Roosevelt and Woodrow Wilson. Progressives rather than puritans, the global temperance movement advocated communal self-protection against the corrupt and predatory "liquor machine" that had become exceedingly rich off the misery and addictions of the poor around the world, from the slums of South Asia to the beerhalls of Central Europe to the Native American reservations of the United States. Unlike many traditional "dry" histories, Smashing the Liquor Machine gives voice to minority and subaltern figures who resisted the global liquor industry, and further highlights that the impulses that led to the temperance movement were far more progressive and variegated than American readers have been led to believe.
The Third Edition of Alan M. Schwitzer, Amber L. Pope, and Lawrence C. Rubin′s Diagnosis and Treatment Planning Skills: A Popular Culture Casebook Approach thoroughly covers essential clinical thinking skills in professional counseling through classic and contemporary popular culture case examples. Fully revised for use with the DSM-5-TR, the text begins with discussion of diagnosis, case conceptualization, and current treatment planning practices, covering the interplay of individual clinical tools and their application in contemporary practice. Twenty DSM-5-TR updated case illustrations follow, representing a diverse range of individual differences and intersecting identities. Students will engage with each case illustration in a start-to-finish application of clinical tools.
Ideology in the Supreme Court is the first book to analyze the process by which the ideological stances of U.S. Supreme Court justices translate into the positions they take on the issues that the Court addresses. Eminent Supreme Court scholar Lawrence Baum argues that the links between ideology and issues are not simply a matter of reasoning logically from general premises. Rather, they reflect the development of shared understandings among political elites, including Supreme Court justices. And broad values about matters such as equality are not the only source of these understandings. Another potentially important source is the justices' attitudes about social or political groups, such as the business community and the Republican and Democratic parties. The book probes these sources by analyzing three issues on which the relative positions of liberal and conservative justices changed between 1910 and 2013: freedom of expression, criminal justice, and government "takings" of property. Analyzing the Court's decisions and other developments during that period, Baum finds that the values underlying liberalism and conservatism help to explain these changes, but that justices' attitudes toward social and political groups also played a powerful role. Providing a new perspective on how ideology functions in Supreme Court decision making, Ideology in the Supreme Court has important implications for how we think about the Court and its justices.
Originally a sect within the Anglican church, Methodism blossomed into a dominant mainstream religion in America during the nineteenth century. At the beginning, though, Methodists constituted a dissenting religious group whose ideas about sexuality, marriage, and family were very different from those of their contemporaries. Focusing on the Methodist notion of family that cut across biological ties, One Family Under God speaks to historical debates over the meaning of family and how the nuclear family model developed over the eighteenth century. Historian Anna M. Lawrence demonstrates that Methodists adopted flexible definitions of affection and allegiance and emphasized extended communal associations that enabled them to incorporate people outside the traditional boundaries of family. They used the language of romantic, ecstatic love to describe their religious feelings and the language of the nuclear family to describe their bonds to one another. In this way, early Methodism provides a useful lens for exploring eighteenth-century modes of family, love, and authority, as Methodists grappled with the limits of familial and social authority in their extended religious family. Methodists also married and formed conjugal families within this larger spiritual framework. Evangelical modes of marriage called for careful, slow courtships, and often marriages happened later in life and produced fewer children. Religious views of the family offered alternatives to traditional coupling and marriage—through celibacy, spiritual service, and the idea of finding one's true spiritual match, which both challenged the role of parental authority within marriage-making and accelerated the turn within the larger society toward romantic marriage. By examining the language and practice of evangelical sexuality and family, One Family Under God highlights how the Methodist movement in the eighteenth century was central to the rise of romantic marriage and the formation of the modern family.
Throughout the book, tables and figures summarize important clinical data and current professional society recommendations, while salient references direct readers to additional information.
Using a critical lens derived from ecopsychology and its praxis, ecotherapy, this book explores the relationships Madeleine L’Engle develops for her characters in a selection of the novels from her three Time, Austin family, and O’Keefe family series as those relationships develop along a human-nonhuman kinship continuum. This is accomplished through an examination both of pairs of novels from the fantastic and the realistic series, and of single novels which stand out as slightly different from the most prominent genre in a given series. Thus, this examination also shows L’Engle’s fluid movement along a fantasy-reality continuum and demonstrates the integration of the three series with each other. Importantly, through examining these relationships and this movement along continuums in these novels, the project demonstrates how ecopsychology and ecotherapy provide strong and important – and as-yet virtually unexplored – intersections with children’s literature.
The most up-to-date, comprehensive guide to outstanding, distinctive lodging options in Mexico No fee accepted for inclusion It's a fact. You will spend more on lodging than on any other aspect of your Mexican getaway. Where you stay deserves special attention when planning your trip. Many travelers to Mexico focus on the wrong hazards, however, and come home disappointed and disillusioned. The discerning, honest reviews in this book can prevent you from wasting hundreds of dollars on a lodging choice that doesn't suit your needs and tastes. This completely revised and updated edition of BEST PLACES TO STAY IN MEXICO provides thoughtful, detailed descriptions of a variety of accommodations in Mexico's four main regions: the Mayan Riviera, the Mexican Riviera, the Extraordinary Interior, and Baja California. * Romantic Hideaways * Resorts and Spas * Beachfront Bargains * Intimate and Affordable Inns * Adventure Retreats * Sophisticated Luxury Hotels
This book is based on the papers presented at the conference on "Mecha nisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk Assessment," held at the National Bureau of Standards on June 2-7, 1985, This volume deals with mechanisms of DNA damage and repair at the molecular level; consequences of unrepaired or misrepaired damage, with major emphasis on carcinogenesis; drugs which bind selectively to altered and potentially damaging DNA sequences; and potential utilization of DNA damage as an endpoint for assessing risks of UV light, ionizing radiations, chemicals, drugs, and hazardous agents in foods. Because the induction of mutations by radiation and genotoxic chemicals has been observed to follow one-hit kinetics in some instances, it is generally assumed that any level of exposure to a DNA-damaging agent may increase the risk of genetic disease or cancer in an exposed population. At the same time, however, there is evidence that although the DNA of living cells is continually damaged by natural background radiation, free radicals, and other naturally occurring processes, most of the damage is normally repaired.
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