Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. - Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens - Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers - Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism - Offers guidance on how to distinguish acquired causes from inborn errors of metabolism
Perspectives on Data Science for Software Engineering presents the best practices of seasoned data miners in software engineering. The idea for this book was created during the 2014 conference at Dagstuhl, an invitation-only gathering of leading computer scientists who meet to identify and discuss cutting-edge informatics topics. At the 2014 conference, the concept of how to transfer the knowledge of experts from seasoned software engineers and data scientists to newcomers in the field highlighted many discussions. While there are many books covering data mining and software engineering basics, they present only the fundamentals and lack the perspective that comes from real-world experience. This book offers unique insights into the wisdom of the community's leaders gathered to share hard-won lessons from the trenches. Ideas are presented in digestible chapters designed to be applicable across many domains. Topics included cover data collection, data sharing, data mining, and how to utilize these techniques in successful software projects. Newcomers to software engineering data science will learn the tips and tricks of the trade, while more experienced data scientists will benefit from war stories that show what traps to avoid. - Presents the wisdom of community experts, derived from a summit on software analytics - Provides contributed chapters that share discrete ideas and technique from the trenches - Covers top areas of concern, including mining security and social data, data visualization, and cloud-based data - Presented in clear chapters designed to be applicable across many domains
According to the accounts of two white officers, on the evening of November 20, 1872, Corporal Daniel Talliafero, of the segregated Black 9th cavalry, was shot to death by an officer’s wife while attempting to break into her sleeping apartment at the military post of Fort Davis, Texas. Historians writing about Black soldiers serving in the West have long accepted the account without question, retelling the story of Daniel Talliafero, the thwarted “rapist.” In Unburied Lives Wilkie takes a different approach, demonstrating how we can “listen” to stories found in things neglected, ignored, or disparaged—documents not consulted, architecture not studied, material traces preserved in the dirt. With a focus on Fort Davis, Wilkie brings attention to the Black enlisted men and non-commissioned officers. In her archaeological accounting, Wilkie explores the complexities of post life, racialized relationships, Black masculinity, and citizenship while also exposing the structures and practices of military life that successfully obscured these men’s stories for so long.
Micro-Facts has proved to be a useful ready reference for practising food microbiologists and others concerned with ensuring the microbiological safety of foods. For the new fifth edition, key sections of the text have been updated and focussed directly on the assurance of safety in the food supply. The information presented remains topical and takes into account the wealth of recent research into food-poisoning organisms and their current relevance to food safety. This fifth edition also gives a more international view of foodborne disease. As in previous editions, the emphasis of this book is on microbiological safety. Foodborne bacterial pathogens - source, incidences of food poisoning, growth/survival characteristics and control - are discussed in detail. Foodborne viruses and protozoa are also examined. The section on spoilage organisms (produced as a supplement to the fourth edition) has been expanded to include a new section on the acetic acid bacteria. The book concludes with brief coverage of HACCP, EC Food Hygiene Legislation, and equipment suppliers. Micro-Facts 5th Edition is an invaluable tool for food microbiologists everywhere, as a source book of information relevant to the prevention of food-poisoning hazards worldwide.
This issue of Hematology/Oncology Clinics will cover aggressive B-Cell Lymphoma and articles to be included are: State of the art therapy for advanced stage DLBCL; DLBCL: Should limited stage patients be treated differently; Role of PET in DLBCL; Management of relapsed DLBCL; The spectrum of double-hit lymphoma; Optimizing outcomes in primary mediastinal B cell lymphoma; The grey zone of unclassifiable lymphomas; as well as many more.
As early as the 1780s, African Americans told stories that enabled them to survive and even thrive in the midst of unspeakable assault. Tracing previously unexplored narratives from the late eighteenth century to the 1920s, Laurie Maffly-Kipp brings to light an extraordinary trove of sweeping race histories that African Americans wove together out of racial and religious concerns. Asserting a role in God's plan, black Protestants sought to root their people in both sacred and secular time. A remarkable array of chroniclers—men and women, clergy, journalists, shoemakers, teachers, southerners and northerners—shared a belief that narrating a usable past offered hope, pride, and the promise of a better future. Combining Christian faith, American patriotism, and racial lineage to create a coherent sense of community, they linked past to present, Africa to America, and the Bible to classical literature. From collected shards of memory and emerging intellectual tools, African Americans fashioned stories that helped to restore meaning and purpose to their lives in the face of relentless oppression. In a pioneering work of research and discovery, Maffly-Kipp shows how blacks overcame the accusation that they had no history worth remembering. African American communal histories imagined a rich collective past in order to establish the claim to a rightful and respected place in the American present. Through the transformative power of storytelling, these men and women led their people—and indeed, all Americans—into a more profound understanding of their interconnectedness and their prospects for a common future.
Describes the two year government undercover operation investigating corruption and illegal practices in the two Chicago commodity exchanges and culminating in the indictments of 46 industry professionals. Describes how these very complicated markets function and how their ``old-boy club'' style first created the problems and later shielded many of its members from investigation and prosecution. A true inside account, it explores rampant fraud and abuse in the futures markets.
The term ‘phenomenology’ has become almost as over-used and emptied of meaning as that other word from Continental Philosophy, namely ‘existentialism’. Yet Husserl, who first put forward the phenomenological method, considered it a rigorous alternative to positivism, and in the hands of Merleau-Ponty, a disciple of Husserl in France, phenomenology became a way of gaining a disciplined and coherent perspective on the world in which we live. When this study originally published in 1977 there were only a few books in English on Merleau-Ponty’s philosophy. It introduced the reader and suggested how his thought might throw light on some of the assumptions and presuppositions of certain contemporary forms of Anglo-Saxon philosophy and social science. It also demonstrates how phenomenology seeks to unite philosophy and social science, rather than define them as mutually exclusive domains of knowledge.
Understanding Yoga Therapy offers a comprehensive and accessible perspective on yoga therapy as a complementary, integrative route to promoting whole-person well-being. Readers will come away from the book understanding how the philosophy, texts, and teachings of yoga benefit a wide range of health conditions. The book is split into three helpful sections: Part I discusses foundational texts and their interpretations; Part II outlines the biopsychosocial-spiritual and neurophysiological model of integrative health pertinent to yoga therapy; and Part III focuses on practical applications separate from the more familiar diagnosis-driven models. Experiential activities and case studies throughout the text illuminate how yogic practices can be incorporated for optimal health. Bridging the ancient and modern, philosophical and scientific, Understanding Yoga Therapy offers a clear explanatory framework for yoga therapists, physicians, allied and complementary healthcare providers, and their patients and students.
Until the recent uprisings in the Middle East and North Africa, the resilience of authoritarian regimes seemed a fundamental feature of regional politics. While economic, political, and internal security policies are most often considered in discussions of regime maintenance, Laurie Brand introduces a new factor, that of national narratives. Portrayals of a country's founding, identity, and bases of unity can be a powerful strategy in sustaining a ruling elite. Brand argues that such official stories, which are used to reinforce the right to rule, justify policies, or combat opponents, deserve careful exploration if we are to understand the full range of tools available to respond to crises that threaten a leadership's hold on power. Brand examines more than six decades of political, economic, and military challenges in two of North Africa's largest countries: Egypt and Algeria. Through a careful analysis of various texts—history and religion textbooks, constitutions, national charters, and presidential speeches—Official Stories demonstrates how leaderships have attempted to reconfigure narratives to confront challenges to their power. Brand's account also demonstrates how leaderships may miscalculate, thereby setting in motion opposition forces beyond their control.
Why are house prices in many advanced economies rising faster than incomes? Why isn't land and location taught or seen as important in modern economics? What is the relationship between the financial system and land? In this accessible but provocative guide to the economics of land and housing, the authors reveal how many of the key challenges facing modern economies - including housing crises, financial instability and growing inequalities - are intimately tied to the land economy. Looking at the ways in which discussions of land have been routinely excluded from both housing policy and economic theory, the authors show that in order to tackle these increasingly pressing issues a major rethink by both politicians and economists is required.
Inquiry-based and easy-to-follow activities help students develop positive attitudes toward science. The experiments are aligned with national standards and cover the areas of physical, earth, and life science as well as health.
Veterinarians, technicians and wildlife caregivers are often called upon to have expertise in raising infant mammals. This book provides clear guidance to raising and caring for a wide variety of domestic, farm, wildlife, and zoo mammals from birth to weaning. Over thirty veterinary technicians, wildlife specialists, and veterinarians from around the world have contributed their expertise to this useful book that covers over 50 mammalian species. Some of the topics covered in each chapter of this book include: * Assessment of the neonate * Specialised equipment * Expected weight gains * Formula selection and preparation * Weaning techniques * Housing * Common medical problems Detailed chapters are devoted to the following animals: * Domestic animals: puppies, kittens, ferrets, sugar gliders and rabbits * Farm animals: foals, kids, llamas and piglets * Wildlife: squirrels, opossums, raccoons, rabbits, deer, foxes, bears, bats, and hedgehogs * Zoo animals: ungulates, non-domestic equids, exotic felids, polar bears, elephants, rhinoceroses, macropods, pinnipeds, large and small primates, lemurs and sloths Dr Laurie Gage is well known for her work and expertise in the rearing of seals, sea lions and walruses and has experience in rearing many other mammalian species.
The author of Luke-Acts constructs a portrait of the Roman military that relies on a variety of literary stereotypes, anticipating that his authorial audience, familiar with the stereotypes, will bring their experience to bear in the process of more fully characterizing the soldiers. Expecting their antipathy, Luke upsets his authorial audience's expectations. Laurie Brink demonstrates that the soldiers, in fact, do not wholly live up to their bad reputations. Engaging, contradicting and transcending the literary stereotypes, Luke creates a progressive portrait of the Roman soldier that demonstrates the attitudes and actions of a good disciple, and that serves as a critique of the authorial audience's original response.
The Juvenile Tradition' covers the late 18th and early 19th century, drawing on the history of childhood and child studies, along with reception study and audience history to recast literary history.
Book Description: 30,000 years of art -- one engaging guide. Can't tell a Manet from a Monet? Not sure why you should want to? Let scholar and author Laurie Adams introduce you to the story behind the history of art. Based on her art survey textbook of the same name, this edition of Art Across Time serves as an entertaining and readable introduction to the history of art. Providing biographical notes and historical context, Adams has created a vivid narrative. Each illustration has been carefully reviewed for color accuracy, and the large percentage of full-page reproductions presents a rare opportunity for readers to examine details of brushwork and texture that are lost in smaller images. All in all, this colorful book is an ideal gift that will compliment any library and interest any reader.
This fully revised third edition brings a fresh approach to the fundamentals of mass media and communication law in a presentation that undergraduate students find engaging and accessible. Designed for students of communication that are new to law, this volume presents key principles and emphasizes the impact of timely, landmark cases on today’s media world, providing an applied learning experience. This new edition offers expanded coverage of digital media law and social media, a wealth of new case studies, expanded discussions of current political, social, and cultural issues, and new features focused on ethical considerations and on international comparative law. Communication Law serves as a core textbook for undergraduate courses in communication and mass media law. Online resources for instructors, including an Instructor’s Manual, Test Bank, and PowerPoint slides, are available at: www.routledge.com/9780367546694
Your essential guide in the assessment and diagnostic process. Step by step, you’ll hone your ability to perform effective health assessments, obtain valid data, interpret the findings, and recognize the range of conditions that can be indicated by specific findings to reach an accurate differential diagnosis. You’ll have coverage of 170 conditions and symptoms across the lifespan at your fingertips. ***** Powerful little clinical assessment tool! “Book required for graduate nursing course. Didn't disappoint! Especially helpful with formulating the differential diagnoses in the care plan...”—Susan, Online Reviewer ***** Really good organization. Helpful descriptions. Easy to find information. “I actually really liked this text for my Advanced Assessment course. I liked how it was broken down by area or body system, and then further broken down my differential diagnosis. The information is organized in a way that makes sense and is super easy to skim to find exactly what you need.”—Alexx, Online Reviewer Expanded, Revised & Updated! Thoroughly updated to reflect the art and the science of primary care practice as well as the newest evidence and changes in health care New Chapter! Differential Studies New & Expanded! Content in Chapter 1 on history taking-techniques and skills for special populations Expanded! Lab diagnostics information, as well as discussions of health disparities, cultural humility, and competency New Content! Genetic testing for pharmacologic prescriptions for psychiatric mental health conditions New! Diagnosis algorithm decision trees designed to help nurses assess and diagnose conditions such as chronic sore throat, chronic insomnia, and more Coverage of 170 conditions and symptoms across the life span—including children, older adults, and pregnant patients. Complaint-focused approach organized by body system, including discussions of complex conditions Step-by-step how tos for taking a focused history, performing a physical based on presenting complaints/problems, and interpreting the findings Guidance on selecting diagnostic tests and interpreting those studies to help narrow down the diagnoses Prediction rules for selected disorders Quick-reference features, including red flags Ÿ assessment pearls Ÿ medications causing symptoms Ÿ and selected causes of symptoms
Historians' conception of plantation life in the American South, both post- and antebellum, derives almost exclusively from the written record, hence mainly from the white owners' perspectives. In Creating Freedom, historical archaeologist Laurie Wilkie pulls the half-opened curtain wider by seeking out the experiences of the majority of people who made their home on plantations: the African American laborers. Specifically, Wilkie examines the lives of four black families who lived at Oakley Plantation in south Louisiana's West Feliciana Parish over the course of one hundred years. Using an innovative blend of archaeological evidence and oral interviews, as well as written documents, she builds a composite of their daily existence that is at once riveting and humanizing in its detail and invaluable in its broader applications. Creating Freedom is in part Wilkie's attempt to understand how African Americans at Oakley Plantation, and by extension most southern blacks, endured the violence and oppression of slavery, Reconstruction, and Jim Crow. It is through their material culture, enhanced by a range of other data, that she descries the complex but uplifting process by which they retained their ties to a cultural past while renegotiating their identity as free persons.
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