This class-tested textbook gives an overview of the structure and functions of proteins and explains how amino acids form a defined structural entity with specific properties. The authors also introduce modern methods for purification and separation of proteins as well as different techniques for analyzing their structural and functional properties. A separate part of the book is devoted to enzymes and kinetics of enzymatic reactions. New in the second edition: Since the development of computing techniques has evolved considerably during the last few years, the text benefits from the addition of a chapter on the use of computing, particularly on the use of Alpha Fold in protein research. This AI-based software can determine the protein structures from the amino acid sequence with excellent reliability. Also included a discussion on the use of molecular dynamicsand a real life example of protein purification.
This class-tested textbook gives an overview of the structure and functions of proteins and explains how amino acids form a defined structural entity with specific properties. The authors also introduce modern methods for purification and separation of proteins as well as different techniques for analyzing their structural and functional properties. A separate part of the book is devoted to enzymes and kinetics of enzymatic reactions. New in the second edition: Since the development of computing techniques has evolved considerably during the last few years, the text benefits from the addition of a chapter on the use of computing, particularly on the use of Alpha Fold in protein research. This AI-based software can determine the protein structures from the amino acid sequence with excellent reliability. Also included a discussion on the use of molecular dynamicsand a real life example of protein purification.
How well designed are the financial regulations that have been imposed after the global financial crisis in 2008–09 and the subsequent euro crisis? Will the new bail-in rules work in a systemic crisis, or do we risk further costly bail-outs by governments? How does monetary policy influence household debt? Have macroprudential tools been well-calibrated? Answers to these questions are crucial for judging the risks that the current corona crisis might also trigger a new financial crisis. The 2020 issue of the Nordic Economic Policy Review consists of six papers, including an introduction by editors Lars Calmfors and Peter Englund.
The modern world has created complex systems that have interrelated concerns. Ecosystems, Society, and Health presents new perspectives on how the challenges relating to these concerns must be examined, not as disparate political narratives, but as dynamic transformational stories that demand integrative systems of research, analysis, practice, and action. Struggles over healthy watersheds, diseases associated with environmental change, and public health impacts of unsafe food exemplify the demand for integrated understanding and action. Contributors argue that traditional science, power politics, and linear ideals of public policy are inadequate to address sustainability, justice, safety, and responsibility. Drawing from a series of case studies that range from nursing, to watershed management, to environmental health and risk communication, this collection strikes an informed balance between practical lessons and a sophisticated theoretical context with which to interpret them. Demonstrating the diverse contextual understanding demanded by today’s complex issues, Ecosystems, Society, and Health is a timely resource with guidance for practitioners, researchers, and educators.
As people are living longer on average than ever before, the number of those with dementia will increase. Because many will live a considerable time at home with their diagnosis, we need to know more about the ways people can adapt to and learn to live with dementia in their everyday lives. Lars-Christer Hyd n argues in this book that to do so will involve re-imagining what dementia really is and what it can mean to the afflicted and their loved ones. One of the most important everyday opportunities for sharing experiences is the simple act of storytelling. But when someone close to you gradually loses the ability to tell stories and cherish the shared history you have together, this is seen as a threat to the relationship, to the feeling of belonging together, and to the identity of the person diagnosed. Therefore, learning about how people with dementia can participate in storytelling along with their families and friends helps to sustain those relationships and identities. In Entangled Narratives, Hyd n not only emphasizes the possibilities that are inherent in collaborative storytelling, but instructs professionals and otherwise healthy relatives to learn how to effectively listen and, ultimately, re-imagine their patients and loved ones as collaborative meaning-makers in their lives.
Hunters in Transition provides a new outline of the early history of the Sámi, the indigenous population of northernmost Europe. Discussing crucial issues such as the formation of Sámi ethnicity, interaction with chieftain and state societies, and the transition from hunting to reindeer herding, the book departs from the common trope whereby native encounters with other cultures, state societies, and “modernity”, are depicted mainly in negative terms. Far from always victimizing “the other”, the interaction with outside societies played a crucial role in generating and maintaining a number of features considered integral to Sámi culture. At the same time the authors also emphasize internal processes and dynamics and show how these have greatly contributed to the diverse historical trajectories with which this book is concerned. Listed by Choice magazine as one of the Outstanding Academic Titles of 2014
Control of Microstructures and Properties in Steel Arc Welds provides an overview of the most recent developments in welding metallurgy. Topics discussed include common welding processes, the thermal cycle during welding, defects that may occur during the welding process, the metallurgy of the material, metallurgical processes in the heat-affected zone and the fused metal, and the relationship between microstructures and mechanical properties. The book's final chapter presents examples of welded joints, illustrating how modern theories are capable of predicting the microstructure and properties of these joints. This book is an excellent resource for welding engineers, metallurgists, materials scientists, and others interested in the subject.
Control systems have come to play an important role in the performance of modern vehicles with regards to meeting goals on low emissions and low fuel consumption. To achieve these goals, modeling, simulation, and analysis have become standard tools for the development of control systems in the automotive industry. Modeling and Control of Engines and Drivelines provides an up-to-date treatment of the topic from a clear perspective of systems engineering and control systems, which are at the core of vehicle design. This book has three main goals. The first is to provide a thorough understanding of component models as building blocks. It has therefore been important to provide measurements from real processes, to explain the underlying physics, to describe the modeling considerations, and to validate the resulting models experimentally. Second, the authors show how the models are used in the current design of control and diagnosis systems. These system designs are never used in isolation, so the third goal is to provide a complete setting for system integration and evaluation, including complete vehicle models together with actual requirements and driving cycle analysis. Key features: Covers signals, systems, and control in modern vehicles Covers the basic dynamics of internal combustion engines and drivelines Provides a set of standard models and includes examples and case studies Covers turbo- and super-charging, and automotive dependability and diagnosis Accompanied by a web site hosting example models and problems and solutions Modeling and Control of Engines and Drivelines is a comprehensive reference for graduate students and the authors’ close collaboration with the automotive industry ensures that the knowledge and skills that practicing engineers need when analysing and developing new powertrain systems are also covered.
From fundamental principles to advanced subspecialty procedures, Miller’s Anesthesia covers the full scope of contemporary anesthesia practice. This go-to medical reference book offers masterful guidance on the technical, scientific, and clinical challenges you face each day, in addition to providing the most up-to-date information available for effective board preparation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Address the unique needs of pediatric patients with guidance from an entire section on pediatric anesthesia. View more than 1,500 full-color illustrations for enhanced visual clarity. Access step-by-step instructions for patient management, as well as an in-depth analysis of ancillary responsibilities and problems. Quickly reference important concepts with ‘Key Points’ boxes integrated into every chapter. Stay current on today's most recent anesthetic drugs and guidelines/protocols for anesthetic practice and patient safety, and access expanded coverage on new techniques such as TEE and other monitoring procedures. Take advantage of the unique, international perspectives of prominent anesthesiologists from all over the world, including the UK, Australia, India, Brazil, and Germany. Remain at the forefront of new developments in anesthesia with coverage of hot topics including Non-OR Anesthesia; Role of the Anesthesiologist in Disasters; Sleep Medicine in Anesthesia; Perioperative and Anesthesia-related Neurotoxicity; Anesthetic Implications of Complementary and Alternative Medicine; and Robotics. Study brand-new chapters on Perioperative Fluid Management; Extracorporeal Support Therapies; Anesthesia for Organ Donation/Procurement; and Malignant Hyperthermia and other Genetic Disorders.
A complete and balanced overview of all aspects of immunocytochemistry is presented providing a clear understanding of their impact on experiment. All available techniques and many diagnostic and research applications are included, as well as practical step-by-step instructions for carrying out recommended methods. Intended for the novice as well as the experienced researchers.
How are people educated to feel that they are part of a nation? What role does religion play in such a process? In this book Lars Laird Iversen takes a close look at Religious Education in Norway in order to find answers to these crucial questions. The intersection of school, religion and national identity is a hotspot for public controversy, in Norway as well as many other countries. Global flows of ideas and migrants have made religious plurality a fact on the ground in Norwegian city- and mediascapes. Iversen investigates the complexities that arise when the nation-shaping ambitions of Norwegian state curriculum authors meets the diverse group of pupils in religious education classes. The book also provides a theoretical discussion on how religious groups, and other groups with identity claims, should be understood, drawing on contemporary debates between social constructionist and critical realist approaches.
The book on sea ice ecology is the ecology of sea ice algae and other microorganism as bacteria, meiofauna, and viruses residing inside or at the bottom of the sea ice, called the sympagic biota. Organisms as seals, fish, birds, and Polar bears relies on sea ice but are not part of this biota. A distinct feature of this ecosystem, is the disappearance (melt) every summer and re-establishing in autumn and winter. The book is organized seasonally describing the physical, optical, biological, and geochemical conditions typical of the seasons: autumn, winter, and spring. These are exemplified with case studies based on author’s fieldwork in Greenland, the Arctic Ocean, and Antarctica but focused on Arctic conditions. The sea ice ecosystem is described in the context of climate change, interests, and effects of a decreasing summer ice extent in the Arctic Ocean. The book contains an up to date description of most relevant methods and techniques applied in sea ice ecology research. This book will appeal to university students at Masters or PhD levels reading biology, geosciences, and chemistry.
This volume explores Nordic textbooks chronologically and empirically from the Protestant reformation to our own time. The chapters are written by scholars from Finland, Denmark, Sweden, and Norway, and deploy a wide range of methods, representing different academic fields.
This book seeks to provide a comprehensive coverage of the important and growing field of ladle metallurgy, including theory, practice, and economics. During the past decade, major advances have been made in the secondary metallurgy of steel and other metals; indeed, secondary metallurgy, that is, the ladle treatment of molten metals, following the melting and refining steps, has become an important and inevitable part of the overall processing sequence. Ladle metallurgy is attractive because it can provide an effective means for adjusting and fine-tuning the composition and temperature of the molten products prior to solidification processing. Ladle metallurgy allows us to produce materials of very high purity and will become increasingly an essential process requirement. Indeed, many of the novel casting techniques will mandate steels of much higher cleanliness than those in current practice. Of course, ladle metallurgy or secondary metallurgy is not limited to steel; indeed, major advances have been made and are being made in the secondary processing of aluminum, aluminum alloys, and many specialty metals.
Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps. All neuroimaging can be considered part of brain mapping. Brain mapping can be conceived as a higher form of neuroimaging, producing brain images supplemented by the result of additional (imaging or non-imaging) data processing or analysis, such as maps projecting (measures of) behaviour onto brain regions (see fMRI). Brain mapping techniques are constantly evolving, and rely on the development and refinement of image acquisition, representation, analysis, visualisation and interpretation techniques. Functional and structural neuroimaging are at the core of the mapping aspect of brain mapping. This book presents the latest research in the field.
For many of us it is the ultimate fear: to die alone. Loneliness is a difficult subject to address because it has such negative connotations in our intensely social world. But the truth is that wherever there are people, there is loneliness. You can be lonely sitting in the quiet of your home, in the still of an afternoon park, or even when surrounded by throngs of people on a busy street. One need only turn on the radio to hear a crooner telling us just how lonesome we can be. In this groundbreaking book, philosopher Lars Svendsen confronts loneliness head on, investigating both the negative and positive sides of this most human of emotions. Drawing on the latest research in philosophy, psychology, and the social sciences, A Philosophy of Loneliness explores the different kinds of loneliness and examines the psychological and social characteristics that dispose people to them. Svendsen looks at the importance of friendship and love, and he examines how loneliness can impact our quality of life and affect our physical and mental health. In a provocative move, he also argues that the main problem in our modern society is not that we have too much loneliness but rather too little solitude, and he looks to those moments when our loneliness can actually tell us profound things about ourselves and our place in the world. The result is a fascinating book about a complex and deeply meaningful part of our very being.
Immunology focuses on the study of immunology. The first half of this book provides a treatise of basic immunology, while the rest is more clinically orientated and illustrates the importance of immune mechanisms for health and disease. This text emphasizes the three good reasons why immunology should be studied. First is that man cannot survive without immunological defense against foreign material. Second is that these same immunological defense mechanisms can cause various forms of tissue damage that result in different diseases. Finally, some immunological reactions can be used as sensitive and highly specific methods for analytical and diagnostically useful determinations of low molecular substances. This publication is primarily intended for students of medicine and natural sciences, as well as clinicians concerned with the field of immunology.
The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.
This impressively comprehensive volume is a long-awaited and worthy successor to the now outdated 1978 classic, Evolution of African Mammals. A must-have reference work for everyone interested in mammalian evolution." David Pilbeam, Harvard University and the Peabody Museum of Archaeology and Ethnology --
From fundamental principles to advanced subspecialty procedures, this text is the go-to reference on the technical, scientific, and clinical challenges professionals face. Features new chapters, new authors, meticulous updates, an increased international presence, and a new full-color design.
From fundamental principles to advanced subspecialty procedures, Miller’s Anesthesia covers the full scope of contemporary anesthesia practice. It is the go-to reference for masterful guidance on the technical, scientific, and clinical challenges you face. Now new chapters, new authors, meticulous updates, an increased international presence, and a new full-color design ensure that the 7th edition continues the tradition of excellence that you depend on. Covers the full scope of contemporary anesthesia practice. Offers step-by-step instructions for patient management and an in-depth analysis of ancillary responsibilities and problems. Incorporates ‘Key Points’ boxes in every chapter that highlight important concepts. Extends the breadth of international coverage with contributions from prominent anesthesiologists from all over the world, including China, India, and Sweden. Features 30 new authors and 13 new chapters such as Sleep, Memory and Consciousness; Perioperative Cognitive Dysfunction; Ultrasound Guidance for Regional Anesthesia; Anesthesia for Correction of Cardiac Arrhythmias; Anesthesia for Bariatric Surgery; Prehospital Emergency and Trauma Care; Critical Care Protocols; Neurocritical Care; and Renal Replacement Therapy. Dedicates an entire section to pediatric anesthesia, to help you address the unique needs of pediatric patients. Presents a new full-color design -- complete with more than 1,500 full-color illustrations -- for enhanced visual guidance.
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