This text explores community policing — a philosophy and an organizational strategy that expands the traditional police mandate. It broadens the focus of fighting crime to include solving community problems, urging police to form a partnership with the people in the community so average citizens can contribute to the police process in exchange for their support and participation. Now includes a chapter on Community Crime Prevention. Profiles feature community policing programs in various cities, and problem-solving case studies cover special topics. Includes: The Ten Principles of Community Policing. Includes ten principles of community policing, profiles in community policing, and problem-solving case studies.
Reflecting sixteen years of intensive fieldwork, this book is a rich chronicle of the daily lives, belief systems, and healing rituals of four highly revered Tibetan shamans forced into exile by the Chinese invasion during the 1950s. Larry Peters lived and studied closely with the shamans in Nepal, learning their belief system, observing and participating in their rituals, and introducing many dozens of students to their worldview. Including photographs of the shamans in ecstatic ritual and trance, this book—one of the most extensive ethnographic works ever done on Tibetan shamanism—captures the end of Tibetan shamanism while opening a window onto the culture and traditions that survived centuries of attack in Tibet, only to die out in Nepal. The violent treatment of shamans by the Buddhist lama has a long history in Tibet and neighboring Mongolia. At one point, shamans were burned at the stake. However, in the mountainous Himalayan terrain, especially in the difficult to reach areas geographically distant from the Buddhist monastic urban centers, shamans were respected and their work revered. Peters’s authoritative and meticulous research into the belief systems of these last surviving representatives of the shamanic traditions of the remote Himalayas preserves, in vivid detail, the techniques of ecstasy, described as pathways to the shamanic spiritual world.
A 672 page, award-winning biography of country music singer Jim Reeves based on hundreds of interviews and Jim's private diaries. Virtually a day by day account of the life of this internationally renowned star.
When R.B. Bennett assumed the leadership of the Conservative Party of Canada in 1926, he inherited a party out of step with a modernizing Canada. Three years later, in the early days of the Depression, he led the Tories to power with a mandate to bring back prosperity. Larry A. Glassford explores the politics of Bennett's leadership, the strategies with which he tackled the Depression, and the reception he and the Conservative party received from voters and press of the day. Bennett's initial efforts to tackle the Depression took the form of activist reaction: raising tariffs, trying to balance the budget, defending the dollar. When these measures all failed to bring recovery, the Bennett-led government edged towards a reform program, creating such permanent institutions as the Canadian Radio Broadcasting Commission (later the CBC), the Bank of Canada, and the Wheat Board. Bennett tried to package his reforms as a Canadian 'New Deal,' a daring move but one that failed to revive the party. The voters were confused: did the Conservative party stand for reaction or reform? Tories themselves could not decide. The Liberals swept back into power in 1935. At the 1938 Conservative convention which chose Bennett's successor, the perplexing dichotomy remained. Fifty years after the Great Depression, the common perception of Bennett is still of the great Canadian capitalist, driving his government, his party, and the country to the never-never land of American-style high tariffs and British-style imperialism. Glassford demonstrates the inaccuracy of that caricature, and offers instead a fresh analysis of Bennett and his party.
Learn to leverage your existing relationships to connect with potential new customers and clients using the easy-to-implement strategies in this book. While many companies allocate significant resources to marketing and advertising, referrals are the easiest, most effective path to more business and greater income. Unfortunately, many people underutilize this powerful asset because they misunderstand the referral game and lack a system for generating warm business leads. Providing great service or products is simply not enough to motivate most people to refer you. Without an effective referral system, you are missing out on business and income that could be yours. The Referral Code shows you exactly what it takes to receive a constant stream of qualified referrals through your existing relationships. You’ll learn how to: * Have people refer you, happily, willingly, and more often * Avoid the 3 biggest mistakes that sabotage referrals * Receive referrals that are warmed up and expecting your call * Attract referrals regardless of the current market conditions * And more “The Referral Code lays out a simple, highly effective system for motivating your clients, friends and associates to connect you with the people they know who need what you offer.” —Daniel H. Pink, author of Drive
The most effective, practical approach to the recognition and management of cardiovascular and cardiopulmonary medicine, MANUAL OF CANINE AND FELINE CARDIOLOGY, 4th Edition takes a user-friendly approach to the challenges and conditions you encounter in everyday practice. This completely revised and updated edition includes vital information on diagnostic modalities and techniques, therapeutic options, surgical procedures, and pharmaceutical management of the dog and cat cardiac patient. This invaluable, practical reference covers the full breadth of canine and feline cardiology diagnosis and management in a straightforward and clinically focused format. - Covers common cardiovascular disorders and practical treatment methods for cardiac failure, cardiac arrhythmias, conduction disturbances, cardiopulmonary arrest, as well as procedures for resuscitation. - Includes numerous reproductions of electrocardiograms, thoracic radiographs, and pressure curves - Vibrant, full-color format helps important material stand out and includes vivid illustrations to aid in diagnosis and treatment. - A user-friendly format with bullet points, tables, key points, and boxes offers at-a-glance access to key information. - Cardiac Surgery chapter provides illustrated, step-by-step coverage of cardiovascular surgical procedures and techniques. - Chapters on Pacemaker Therapy and Cor Pulmonale and Pulmonary Thromboembolism expand the scope of coverage. - A completely updated drug formulary presents the most current therapies used to pharmacologically manage cardiovascular disease. - Twenty-nine expert contributors share their knowledge and clinical exposure to ensure you are using the most trustworthy and up-to-date information available.
A re-editing of F.N. Robinson's second edition of The works of Geoffrey Chaucer published in 1957 by the team of experts at the Riverside Institute who have greatly expanded the introductory material, explanatory notes, textual notes, bibliography and glossary. The result of many years' study. The Riverside Chaucer is the most authentic and exciting edition available of Chaucer's complete works.
This second book in the Seraffyn cruising series begins with their arrival on the southwest coast of England where they coasted eastward, stopping where fancy held them, where good friends were made, to winter at Pooole, and work to pay for th enext leg of their voyage - toward the Baltic. Denmark, Sweden, Finland were full of welcoming and interesting people and an almost invisible bureacracy. But things were definitely different when they reached Poland were armed guards watched while the poeple greeted them with flowers, fruits and sweets. Their foray behind the Iron Curtain of the 1970's introduced them to some of the people who lead the Solidarity Movement, the force that eventually toppled the Soviet Union. You'll be right on board as they weather a fierce mast-under broach in a Baltic gale and through the wintery North Seas. Here is a feast for the fantiasies of stay-at-homes and a warm account of just two years of the lives of two people who have lived in a wide adventurous world for more than four decades. Their motto -- Go Small, Go Simple, Go Now has encouraged thousands of other sailors to take the plunge. And this book is an entertaining instruction manual on how to live a rich life on very little money. "Lin Pardey has, in her deceptively simple and fresh-faced style, told the story of an unusual and appealing marriage partnership, a speical way of life. Yachtsmen will enjoy the technical description of the problems of maneuvering in the tight harbours and unmapped channels...the perils of heavy seas in a small boat. But what is remarkable is that she can draw a nonsailor into these special subjects and make them as comprehensible and absorbing to a landlubber as they would be to someone about to set out on the same itinerary in a small boat of his own." R. Sokolov, NewYork Times Book Review
Why leaders, not citizens, are the driving force in Europe’s crisis of democracy An apparent explosion of support for right-wing populist parties has triggered widespread fears that liberal democracy is facing its worst crisis since the 1930s. Democracy Erodes from the Top reveals that the real crisis stems not from an increasingly populist public but from political leaders who exploit or mismanage the chronic vulnerabilities of democracy. In this provocative book, Larry Bartels dismantles the pervasive myth of a populist wave in contemporary European public opinion. While there has always been a substantial reservoir of populist sentiment, Europeans are no less trusting of their politicians and parliaments than they were two decades ago, no less enthusiastic about European integration, and no less satisfied with the workings of democracy. Anti-immigrant sentiment has waned. Electoral support for right-wing populist parties has increased only modestly, reflecting the idiosyncratic successes of populist entrepreneurs, the failures of mainstream parties, and media hype. Europe’s most sobering examples of democratic backsliding—in Hungary and Poland—occurred not because voters wanted authoritarianism but because conventional conservative parties, once elected, seized opportunities to entrench themselves in power. By demonstrating the inadequacy of conventional bottom-up interpretations of Europe’s political crisis, Democracy Erodes from the Top turns our understanding of democratic politics upside down.
This practical book is full of quick and easy-to-use lessons that promote meaningful writing practice. Teachers will find strategies organized alphabetically and in a consistent format that will inspire students to plan, develop, and share their writing. The lessons allow teachers to choose what they need to meet the diverse needs of students in grades one through eight. Each independent lesson guides students through the writing process with information about a writing form, along with suggested literature sources. Tips throughout the book will help students successfully write to narrate, to inform, to entertain, to persuade, to respond, and to enjoy.
In recent years, linguistics has become increasingly more willing to allow some type of representation of 'meaning' in the study of language. However, most approaches deal with sentence or utterance meaning and thereby ignore the meaning of linguistic form. Yet no description of linguistic semantics can be complete without a comprehensive account between meaning and form. This study returns to the problem of form and meaning by presenting a detailed account of certain forms in Spanish which have traditionally been called grammatical forms, or grammatical categories, and associated with grammatical meaning. It is suggested that not all linguistic forms represent the same kind of 'meaning', and that a subset of grammatical forms constitute a highly organized system that parallels phonology and syntax in its capacity to explain variation at the level of discourse. The book opens with an introductory chapter, which is followed by five chapters on the analysis of the Spanish verbal system. In Chapter 7 problems of the noun phrase (the meaning of determiners and grammatical number) are discussed. Chapter 8 offers an explanation of the meaning of the direct object a, and in Chapter 9 a crosslinguistic study of the semantics of Spanish and English is presented. A summary of findings is given in Chapter 10, along with a further consideration of the goals and procedures of semantic analysis.
The evolution of Shakespeare's comedy, in Larry Champion's view, is apparent in the expansion of his comic vision to include a complete reflection of human life while maintaining a comic detachment for the audience. Like the other popular dramatists of Elizabethan England, Shakespeare used the diverse comic motifs and devices which time and custom had proved effective. He went further, however, and created progressively deeper levels of characterization and plot interaction, thereby forming characters who were not merely devices subordinated to the needs of the plot. Shakespeare's development as a comic playwright, suggests Champion, was "consistently in the direction of complexity or depth of characterization." His earliest works, like those of his contemporaries, are essentially situation comedies: the humor arises from action rather than character. There is no significant development of the main characters; instead, they are manipulated into situations which are humorous as a result, for example, of mistaken identity or slapstick confusion. The ensuing phase of Shakespeare's comedy sets forth plots in which the emphasis is on identity rather than physical action, a revelation of character which occurs in one of two forms: either a hypocrite is exposed for what he actually is or a character who has assumed an unnatural or abnormal pose is forced to realize and admit the ridiculousness of his position. In the final comedies involving sin and sacrificial forgiveness, however, character development is concerned with a "transformation of values." Although each of the comedies is discussed, Champion concentrates on nine, dividing them according to the complexity of characterization. He pursues as well the playwright's efforts to achieve for the spectator the detached stance so vital to comedy. Shakespeare obtained this perspective, Champion observes, through experimentation with the use of material mirroring the main action--mockery, parody, or caricature--and through the use of a "comic pointer" who is himself involved in the action but is sufficiently independent of the other characters to provide the audience with an omniscient view.
Women at War Although war was traditionally the purview of men, the realities of America's Civil War often brought women into the conflict. They served as nurses, sutlers, and washerwomen. Some even disguised themselves as men and joined the fight on the battlefield. In the border state of Missouri, where Southern sympathies ran deep, women sometimes clashed with occupying Union forces because of illegal, covert activities like spying, smuggling, and delivering mail. When caught and arrested, the women were often imprisoned or banished from the state. In at least a couple of cases, they were even sentenced to death. Join award-winning author Larry Wood as he chronicles the misadventures and ordeals of the lady rebels of Missouri.
Onward to Chicago charts the evolution of the northeastern Illinois freedom network and shows how, despite its small Black community, Chicago emerged as a point of refuge. While traditional histories of the Underground Railroad in Illinois start in 1839, and focus largely on the romanticized tales of white men, Larry A. McClellan reframes the story, not only introducing readers to earlier freedom seekers, but also illustrating that those who bravely aided them were Black and white, men and women"--
Designed for rapid reference at the point of care, Manual of Clinical Anesthesiology is the clinician’s go-to resource for practical, clinically focused information on all aspects of anesthesia management. The comprehensive second edition consolidates multidisciplinary expertise in one resource, offering revised and updated content in a highly visual, portable format, with short, easy-to-read chapters, margin icons noting pearls and pitfalls, and more.
A highly practical guide to public health intervention development. This book has been developed to assist anyone involved with effective health promotion project design. It cuts through the complex theories and technical frameworks to provide a 6 step formula for creating effective and sustainable interventions. Key features Adopts a pragmatic approach that addresses barriers and challenges to project delivery Utilises the Six Steps in Quality Intervention Development framework - a unique model designed specifically to improve intervention planning Combines the theory and concepts behind intervention development with practical methods of delivery on the ground Includes detailed case studies that provide examples of how the six steps can be used for successful intervention design As the health needs of an increasingly globalised world continue to evolve and shift, effective planning and intervention work will only become more important. Written by leading researchers and experts who draw on a wealth of experience in the field, this book will be essential reading for any student, practitioner or policy maker requiring an understanding of practical intervention design.
CIMA Official Learning Systems are the only coursebooks recommended by CIMA. Written by a team of experts that include past and present CIMA examiners and markers, they contain everything you need to know. Each book maps to the syllabus chapter by chapter to help you learn effectively and reinforce learning with features including: - comprehensive coverage of the whole syllabus - step by step coverage directly linked to CIMA's Learning Outcomes - up to date examples and case studies - practice questions to test knowledge and understanding- - integrated readings to increase understanding of key theories- colour used throughout to highlight key learning points * The Official Learning systems are the only study materials endorsed by CIMA * Key sections written by former examiners for the most accurate, up-to-date guidance towards exam success * Complete integrated package incorporating syllabus guidance, full text, recommended articles, revision guides and extensive question practice
This authoritative research tool covers all aspects of California corporate law and practice, providing clear, reliable guidance to the laws, legislative history, and major case law holdings, as well as the authors' well-known expertise and advice on approaching and understanding key corporate transactions. There is no better source on how to handle all key corporate transactions, from corporate formation and governance to takeovers and bankruptcies. Completely current, there is full coverage and insightful, expert analysis of all the critical new issues affecting California corporate law practice, including: What are the various business entities available in California?What are the methods and issues involved in forming those entities?What are the particular benefits of, and restrictions on, using a Limited Liability Company in California?What are the issues involved in financing a California corporation?What are the fiduciary duties imposed upon directors, officers, and controlling shareholders of California corporations?How do you provide notice and hold meetings of directors and shareholders of California corporations?What are the restrictions imposed upon officers and directors in the operation of California corporations?Under what circumstances can a California corporation pay a dividend or make a distribution of property to its shareholders?What are the issues involved in acquiring California corporations, whether by merger, purchase of stock, or purchase of assets?How and under what circumstances can a California corporation be dissolved?What are the issues and requirements faced by a foreign corporation conducting business in California?
Endocrinology: Adult and Pediatric: Reproductive Endocrinology is a new eBook from the same experts responsible for the highly acclaimed two-volume Endocrinology clinical reference book. It puts all of the latest advances in adult and pediatric reproductive endocrinology at your fingertips, instantly accessible on your favorite eReader - so you can give your patients the benefit of today’s best know-how. Stay abreast of the newest knowledge in reproductive endocrinology, including endocrinology of sexual behavior and gender identity; genetic pathways that control gonadal development and sex differentiation; management of PCOS and hirsutism; management of male androgen deficiency; management of gynecomastia; and much more. Effectively review the causes and management of precocious or delayed puberty. Count on all the authority that has made Endocrinology, 6th Edition, edited by leading endocrinologists Drs. Jameson and DeGroot, the go-to clinical reference for endocrinologists worldwide. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.
This thoughtful book is rooted in the belief that teachers can lead their students to develop their reading tastes and grow in their love of reading at the same time as supporting and stretching students in their meaning-making experiences. This practical resource highlights more than 50 instructional strategies that invite students to work inside and outside a book through reading, writing, talk, and arts experiences. It highlights the work of guest voices that include classroom teachers, occasional teachers, special education teachers, and librarians who share their best literacy practices. Take Me to Your Readers uses 5 essential areas to structure classroom experiences through children's literature: Motivation; Theme Connections; Genre Connections; Cross-Curricular Connections; and Response. Extensive booklists, teaching tips, a wide range of activities, and reproducible pages provide practical support. Ultimately, this book is designed to take teachers to their readers and start them on a lifelong journey through great books!
Nicholas Watson craves a little mystery and excitement in his life. After all, he is an undercover agent working for a US counterterrorism unit which is not exactly the kind of lifestyle that one should have when searching for someone to settle down with. He yearns for love and intimacy but feels that he will never find it, especially since he has already experienced one failed marriage. His life goes into a tizzy when Kalyna, a beautiful and mysterious European, walks into his life. Nick discovers she also works for her respective government's counterterrorism unit. When Nick and Kalyna are thrown together in a work-related encounter, they fall deeply in love which is not part of their assignment. Because of their line of work, they can never make their relationship known. They continue to be placed together in professional situations, only to be separated again when the work is done. Miraculous happenings against unexpected complications that bring conflict to their newfound love simply fuel the fire of their journey. Dangerous circumstances and life itself rises against the possibility of such a relationship between them. Yet the drive for fulfillment of this personal desire in their lives continues to keep the pages of hope turning for the faint possibility of them finally being together freely. Can love truly conquer all? Can Nick and Kalyna overcome their secret lives in order to be together openly, or will they have to forever keep theirLove Undercover?
According to Larry Chapp, theology is left with two dire options in the aftermath of naturalism's apparent cultural triumph: provide modernity with an intellectually cogent theological vision or perish, along with that same culture, in the wasteland of our nihilism. Chapp's important book is grounds for hope that theology may live to see another day and that the pervasive nihilism may not have the last word. He correctly diagnoses the intellectual and cultural dangers posed by so-called scientific naturalism, lifting the lid on its alleged metaphysical neutrality and exposing this naturalism for what it fundamentally is: a bad theology which doesn't know itself. And more importantly still, he restores theology to its proper cosmological scope. Not only does "creation" become intellectually compelling in Chapp's deft hands, it elicits wonder and praise for its Creator and restores what is human in us. This is a hopeful development indeed and a sign of an indispensible book. - Michael Hanby, on back cover.
An anthology of landmark scholarship on the histories of the common soldier in the U.S. Civil War In 1943, Bell Wiley's groundbreaking book Johnny Reb launched a new area of study: the history of the common soldier in the U.S. Civil War. This anthology brings together landmark scholarship on the subject, from a 19th century account of life as a soldier to contemporary work on women who, disguised as men, joined the army. One of the only available compilations on the subject, The Civil War Soldier answers a wide range of provocative questions: What were the differences between Union and Confederate soldiers? What were soldiers' motivations for joining the army—their "will to combat"? How can we evaluate the psychological impact of military service on individual morale? Is there a basis for comparison between the experiences of Civil War soldiers and those who fought in World War II or Vietnam? How did the experiences of black soldiers in the Union army differ from those of their white comrades? And why were southern soldiers especially drawn to evangelical preaching? Offering a host of diverse perspectives on these issues, The Civil War Soldier is the perfect introduction to the topic, for the student and the Civil War enthusiast alike. Contributors: Michael Barton, Eric T. Dean, David Donald, Drew Gilpin Faust, Joseph Allen Frank, James W. Geary, Joseph T. Glaatthaar, Paddy Griffith, Earl J. Hess, Thomas Wentworth Higginson, Perry D. Jamieson, Elizabeth D. Leonard, Gerald F. Linderman, Larry Logue, Pete Maslowski, Carlton McCarthy, James M. McPherson, Grady McWhiney, Reid Mitchell, George A. Reaves, Jr., James I. Robertson, Fred A. Shannon, Maris A. Vinovskis, and Bell Irvin Wiley.
Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects – that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, standard therapies. The large body of evidence supporting these concepts makes them deserving of further research and well-designed clinical trials. It discusses lipid, cholesterol, glutamine, and glucose metabolisms and their impact on prostate cancer. Additionally, it explains how current established drugs can be repurposed to improve treatment outcomes. The concepts set out in the book, that deal with cancer at the cellular/molecular level, help identify new avenues of research and treatments to pursue that do not affect well-being whilst offer consistent benefits. Since most practicing physicians have not studied basic biochemistry since medical school, each chapter begins with a brief review of the topic to facilitate an understanding of the metabolically-oriented approach to targeting prostate cancer. Conventional treatments are not discussed here since they are covered in textbooks and specialized updates that abound in the medical literature. It is a valuable resource for cancer researchers, oncologists, clinicians and members of biomedical field who want to learn more about prostate cancer metabolism and how to apply recent findings in the field to bedside. - Explains the basic aspects of prostate cancer metabolism, including its biochemistry which has a pivotal role in clinical practice - Discusses new drugs and nutraceuticals with a metabolism-centered approach - Offers practical bedside approach in combination with molecular and biochemical fundamentals to help readers identify and provide the best treatment to their patients
In politics, as in so many other areas, California is unique. The state's economy - the largest in the nation, and sixth largest in the world - is given to dramatic swings. Its legislative system is often defined by gridlock on matters large and small. The use of the initiative, one of the tools of "direct democracy", has become commonplace. Over the years, California has had more than its share of political turmoil. But for pure melodrama, nothing matches the 2003 campaign to recall the state's sitting governor, Gray Davis. Recall! relates the latest and most dramatic chapter in the political history of the Golden State. The authors are recognized experts on California politics and regular local television political analysts. They provide fascinating coverage of the events leading up to Davis's replacement by bodybuilder-turned actor-turned politician Arnold Schwarzenegger; describe the large and colorful cast of characters involved in the special election; and demonstrate how California's one-of-a-kind mix of political, economic, and social circumstances made it all possible.
A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume: Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry Details many of the recent developments in organic chemistry that prepare target molecules Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.
CIMA's Official Learning System has been written by former CIMA examiners in conjunction with the CIMA faculty. They provide a clear logical route through the new syllabus to specifically prepare students to pass, first time. CIMA Official Learning Systems include: * Step-by-step coverage directly linked to the CIMA syllabus learning outcomes * Chapter and topic summaries * Extensive question practice * Complete Revision section * CBA style mock exam * Two colour layout for easy navigation The ring binder format allows you to add in your notes as you work through the system, and if attending classes, to just take the chapter you need. CIMA Official Learning Systems are the only materials written and endorsed by the CIMA Faculty. * Re-engineered to meet the demands of the new CIMA Certificate in Business Accounting 2006 syllabus * Complete integrated package incorporating syllabus guidance, full text, recommended articles, revision guides and extensive question practice * CIMA Official Learning Systems are the only materials written and endorsed by the CIMA Faculty.
Featuring hundreds of full-color photomicrographs, Rodak's Hematology: Clinical Principles and Applications, 5th Edition prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This text also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Clinical lab experts Elaine Keohane, Larry Smith, and Jeanine Walenga also cover key topics such as working in a hematology lab, the parts and functions of the cell, and laboratory testing of blood cells and body fluid cells. Instructions for lab procedures include sources of possible errors along with comments. Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios. Hematology instruments are described, compared, and contrasted. UPDATED, full-color illustrations make it easier to visualize hematology concepts and show what you'll encounter in the lab, with images appearing near their mentions in the text so you don't have to flip pages back and forth. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. A bulleted summary makes it easy to review the important points in every chapter. Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end. A glossary of key terms makes it easy to find and learn definitions. NEW coverage of hematogones in the chapter on pediatric and geriatric hematology helps you identify these cells, a skill that is useful in diagnosing some pediatric leukemias. UPDATED chapter on molecular diagnostics covers new technology and techniques used in the lab.
pH Deregulation as the Eleventh Hallmark of Cancer presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment. pH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer. Proposes that pH deregulation should be considered as an independent hallmark of cancer from metabolic reprogramming due to its impact on all other hallmarks (based on seminal work of Hanahan and Weinberg) Explains basic issues of cancer pH deregulation and its consequences in a simple and concise manner Discusses the subject from the start with very elementary concepts on pH and pH regulation to help readers understand key concepts without proper background Presents key concepts through original illustrations and table for easy comprehension
Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods, Volume Two presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds. - Addresses current issues of resistance, along with combination uses for resistant parasites - Presents useful, authoritative information (chemical, pharmaceutical, clinical, etc.) for the pyrantel family of compounds - Includes a discussion on screening methods in combination therapies - Provides cutting-edge material for an evolving area of scientific discussion - Includes in vitro and in vivo screens and parasite maintenance and culture methods
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