Larry M. Miller's Books

Modern Supercritical Fluid Chromatography

Carbon Dioxide Containing Mobile Phases

By: Larry M. Miller,J. David Pinkston,Larry T. Taylor

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Modern Supercritical Fluid Chromatography

Carbon Dioxide Containing Mobile Phases

By: Larry M. Miller,J. David Pinkston,Larry T. Taylor

Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.

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Page Count

458

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119626005

ISBN 13

9781119626008

Social Skills Assessment and Training with Children

An Empirically Based Handbook

By: Larry Michelson,Don P. Sugai,Randy P. Wood,Alan E. Kazdin

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Social Skills Assessment and Training with Children

An Empirically Based Handbook

By: Larry Michelson,Don P. Sugai,Randy P. Wood,Alan E. Kazdin

The purpose of this book is to provide readers with sufficient knowledge regard ing social skills assessment and training with children so that they can imple ment and evaluate social skills programs on their own. Increased interest in promoting children's social skills has stemmed in part from advances in research that have shown the importance of childhood social competency for adjustment in both childhood and adulthood. There is a growing need for assessment and training methods that can be utilized by diverse groups of professionals and paraprofessionals. This book is intended for mental health workers, teachers, educators, clinicians, and child-care personnel. The book thoroughly reviews the literature to acquaint readers with relevant findings on social skills and to pro vide discussion regarding contemporary issues and assessment techniques. Sub sequently, comprehensive procedures in the training of children's social skills are presented. Readers are also provided with 16 detailed training modules, each of which comprises a rationale, instructions, Scripts, and homework assign ments. These modules are designed to permit effective implementation of social skills training programs. Moreover, they provide a structured and program matically designed format that builds in clinical flexibility for their use with individual children or groups of children. These modules are followed by a clinical-issues section designed to address potential obstacles to effective training. Following these major sections, two appendixes have been included in the book. The first appendix is a step-by-step description of how to conduct an assessment.

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Page Count

267

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1489903488

ISBN 13

9781489903488

Peterson's Principles of Oral and Maxillofacial Surgery

By: Larry J. Peterson

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Peterson's Principles of Oral and Maxillofacial Surgery

By: Larry J. Peterson

Peterson's Principles of Oral and Maxillofacial Surgery, Third Edition, encompasses a wide range of diverse topics making it a unique text amongst the medical and dental specialties. The purpose of this concise, easy-to-read two-volume text is to provide an authoritative and currently referenced survey of the specialty of Oral and Maxillofacial Surgery. It contains the necessary information for clinicians and is an ideal reference text for preparation for board certification in the specialty.

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Page Count

1686

Publisher

PMPH-USA

Published Date

ISBN 10

1607951118

ISBN 13

9781607951117

Privileged Structures in Drug Discovery

Medicinal Chemistry and Synthesis

By: Larry Yet

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Privileged Structures in Drug Discovery

Medicinal Chemistry and Synthesis

By: Larry Yet

A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume: Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry Details many of the recent developments in organic chemistry that prepare target molecules Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.

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Page Count

562

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118686357

ISBN 13

9781118686355

Endocrinology: Adult and Pediatric E-Book

By: J. Larry Jameson,Leslie J. De Groot

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Endocrinology: Adult and Pediatric E-Book

By: J. Larry Jameson,Leslie J. De Groot

Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

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Page Count

3707

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

032332195X

ISBN 13

9780323321952

Harrison's Principles of Internal Medicine 20/E (Vol.1 & Vol.2) (ebook)

By: Dennis L. Kasper,Anthony S. Fauci,Stephen L. Hauser,Dan L. Longo,J. Larry Jameson,Joseph Loscalzo

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Harrison's Principles of Internal Medicine 20/E (Vol.1 & Vol.2) (ebook)

By: Dennis L. Kasper,Anthony S. Fauci,Stephen L. Hauser,Dan L. Longo,J. Larry Jameson,Joseph Loscalzo

Publisher's Note: There is a new edition of Harrison's Principles of Internal Medicine. The 21st edition contains the most timely and comprehensive updates from the world's top experts. MASTER MODERN MEDICINE! Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible. Essential for practice and education, the landmark 20th Edition features: Thoroughly revised content—covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison’s. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care. State-of-the-art coverage of disease mechanisms: Harrison’s focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison’s summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system’s role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals. All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine—Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine. Important and timely new chapters—such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more—offer the very latest, definitive perspectives on must-know topics in medical education and practice. Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and pres

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3790

Publisher

McGraw Hill Professional

Published Date

ISBN 10

1259644049

ISBN 13

9781259644047

Intercultural Communication

A Reader

By: Larry A. Samovar,Richard E. Porter

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Intercultural Communication

A Reader

By: Larry A. Samovar,Richard E. Porter

This broad-based, highly engaging reader, compiled by the authors who defined the course, introduces students to the theoretical and practical aspects of intercultural communication. It includes a balance of articles with readings that discuss the classic ideas that laid the groundwork for this field, as well as those that investigate the field's latest research and ideas.

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Page Count

452

Published Date

ISBN 10

0534042937

ISBN 13

9780534042936

Book's by Larry M. Miller

Modern Supercritical Fluid Chromatography

Modern Supercritical Fluid Chromatography

Social Skills Assessment and Training with Children

Social Skills Assessment and Training with Children

Peterson's Principles of Oral and Maxillofacial Surgery

Peterson's Principles of Oral and Maxillofacial Surgery

Privileged Structures in Drug Discovery

Privileged Structures in Drug Discovery

Endocrinology: Adult and Pediatric E-Book

Endocrinology: Adult and Pediatric E-Book

Harrison's Principles of Internal Medicine 20/E (Vol.1 & Vol.2) (ebook)

Harrison's Principles of Internal Medicine 20/E (Vol.1 & Vol.2) (ebook)

Intercultural Communication

Intercultural Communication

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