Larry Carbone, a veterinarian who is in charge of the lab animal welfare assurance program at a major research university, presents this scholarly history of animal rights. Biomedical researchers, and the less fanatical among the animal rights activists will find this book reasonable, humane, and novel in its perspective. It brings a novel, sociological perspective to an area that has been addressed largely from a philosophical perspective, or from the entrenched positions of highly committed advocates of a particular position in the debate.
The author is a lifelong resident of Connecticut. The Very First Thing I Remember is a story about a boy growing up in one of the largest cities in the statean old mill town that had seen better years. The story is told through the eyes of a five-year-old child growing into adolescence. The voyage that the main character takes in this story is not that special or even particularly interesting in the eyes of the author. This book is simply him telling a little story about his own personal journey into learning.
Advertising Management in a Digital Environment: Text and Cases blends the latest methods for digital communication and an understanding of the global landscape with the best practices of the functional areas of management. Divided into three core sections, the book provides a truly holistic approach to Advertising Management. The first part considers the fundamentals of advertising management, including leadership, ethics and corporate social responsibility, and finance and budgeting. The second part considers human capital management and managing across cultures, whilst the third part discusses strategic planning, decision making and brand strategy. To demonstrate how theory translates to practice in advertising, each chapter is illustrated with real-life case studies from a broad range of sectors, and practical exercises allow case analysis and further learning. This new textbook offers an integrated and global approach to Advertising Management and should be core or recommended reading for undergraduate and postgraduate students of Media Management, Advertising, Marketing Management and Strategy, Communications and Public Relations. The applied approach provided by case study analysis makes it equally suitable for those in executive education and studying for professional qualifications.
The Second Edition of The Handbook of Financing Growth has been designed to help leaders and advisors gain a solid understanding of the financing strategies, sources, and transactions that will allow them to excel in such an unpredictable environment. Written by an experienced group of practitioners who operate within this dynamic market and fully updated to reflect new market realities this reliable resource outlines the full spectrum of funding alternatives currently available to emerging growth and middle-market companies and presents the practical strategies and techniques you need to be aware of when considering the capitalization, growth, or sale of your, or your client's, company. New material found in this Second Edition includes detailed discussions of positioning a business for value creation before the transaction and how your financing strategy fits into the overall plan for growing and raising capital as well as creating an exit. Among various techniques, the authors address buyouts and recapitalizations as two alternatives to create shareholder liquidity and potentially finance future growth. A new chapter on M&A addresses the acquisition process and how to fund acquisitions and external growth initiatives, while additional case studies highlight bank financing alternatives and growth equity.
Cases in Advertising Management" offers a wide range of short, medium-length, and longer cases, all designed to illuminate the topics covered in an Advertising Management course. The book can stand alone, or, for instructors who wish to incorporate a combined casebook and textbook approach, it can be adopted alongside any standard text, including Advertising Management by the same authors.The book features actual real-life cases that reflect current trends in the advertising and promotion industry, with a strong emphasis on digital media and integrated marketing communications. A detailed introduction ('How to Analyze a Case Study') is followed by 30 cases, covering a full range of topics for a semester-long course, including financial management, business planning, strategic planning, budgeting, human resource management, and managing change.
This book represents the first critical survey of a section of a rich Australian corpus of chamber music. The author has included various instrumental combinations with piano as well as vocal music with piano. The survey is chronological, as well as by composer. An appendix to the work provides source material for future research into this area. The research has concentrated on progressive modernist music by Australian composers. The commentary utilizes the author's rich experience as composer, pianist and educator.
The truth about the American Revolution is under attack. Despite what you may have learned in school, it wasn't a rich slaveholder's war fought to "maintain white privilege." In fact, the War of Independence wasn't about maintaining any status quo—it was the world's first successful bottom-up revolution by the people, ushering in a new dawn of liberty that history had never seen before. But with left-wingers dominating the teaching of history, where can you go for the true story of the unprecedented events that made the United States the worlds greatest nation? Now bestselling historian Larry Schweikart has teamed up with author Dave Dougherty to write the ground-breaking patriotic history you've always wanted to read about the foundation of our unique nation. The Politically Incorrect Guide to the American Revolution reveals: Four key factors that applied only in America, making it impossible to replicate the Revolution anywhere else Why it matters that the Patriot ghting force was overwhelmingly Scotch-Irish The key role of Protestantism: which denominations tended to become Patriots, and which Tories How Americans were different from the Europeans and English even at the outset of the Revolution How the casualties of the deadliest war in American history are routinely underreported How our Revolution became a model for hundreds of others—that all failed Schweikart and Dougherty take on the left-wing myths—starting with the Marxist narrative of the Revolution in Howard Zinn's nearly ubiquitous A People's History of the United States—and uncover the truth about America's beginning.
The eight chapters of this volume explore the contribution that numismatic studies can make to a serious investigation of the New Testament and its world. The first two chapters focus on themes connected with the reign of the Julio-Claudian emperors, the next three on aspects of Pauline letters that may be illuminated by specific issues of Roman coinage, and the final three concentrate on coinage minted during the reign of the Emperor Hadrian.
Clergy have historically been represented as figures of authority, wielding great influence over our society. During certain periods of American history, members of the clergy were nearly ever-present in public life. But men and women of the clergy are not born that way, they are made. And therefore, the matter of their education is a question of fundamental public importance. In Clergy Education in America, Larry Golemon shows not only how our conception of professionalism in religious life has changed over time, but also how the education of religious leaders have influenced American culture. Tracing the history of clergy education in America from the Early Republic through the first decades of the twentieth century, Golemon tracks how the clergy has become increasingly diversified in terms of race, gender, and class in part because of this engagement with public life. At the same time, he demonstrates that as theological education became increasingly intertwined with academia the clergy's sphere of influence shrank significantly, marking a turn away from public life and a decline in their cultural influence. Clergy Education in America offers a sweeping look at an oft-overlooked but critically important aspect of American public life.
This book is about helping troubled young people who are searching separately for security, identity, and purpose in their lives. Childhood and adolescence are pivotal stages in the quest to belong, to become somebody, and to be worth something. Children need stimulation, affection, and guidance in order to develop their potentials, but many are reared in environments that deprive them of these nutriments. Adolescents approach the threshold of independence with only the experiences gained from childhood; many lack the support of significant actions. Those who encounter difficulty in navigating through these turbulent years are to be identified by society as troubled or troublesome. These children and youth present challenges that do not yield to simple panaceas. Although no simple approach holds all the answers, bridging various concepts of education and treatment offers the best opportunity for creating positive changes. The authors refer to this process as -re-education- with full awareness that this term has been used in a variety of philosophical contexts including behavioral, ecological, and psychodynamic views.
Endocrinology: Adult and Pediatric: Reproductive Endocrinology is a new eBook from the same experts responsible for the highly acclaimed two-volume Endocrinology clinical reference book. It puts all of the latest advances in adult and pediatric reproductive endocrinology at your fingertips, instantly accessible on your favorite eReader - so you can give your patients the benefit of today’s best know-how. Stay abreast of the newest knowledge in reproductive endocrinology, including endocrinology of sexual behavior and gender identity; genetic pathways that control gonadal development and sex differentiation; management of PCOS and hirsutism; management of male androgen deficiency; management of gynecomastia; and much more. Effectively review the causes and management of precocious or delayed puberty. Count on all the authority that has made Endocrinology, 6th Edition, edited by leading endocrinologists Drs. Jameson and DeGroot, the go-to clinical reference for endocrinologists worldwide. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.
This book is about the drift, diffusion, and reaction of ions moving through gases under the influence of an external electric field, the gas temperature, and the number density. While this field was established late in the 19th century, experimental and theoretical studies of ion and electron swarms continue to be important in such varied fields as atomic and molecular physics, aeronomy and atmospheric chemistry, gaseous electronics, plasma processing, and laser physics. This book follows in the rigorous tradition of well-known older books on the subject, while at the same time providing a much-needed overview of modern developments with a focus on theory. Graduate students and researchers new to this field will find this book an indispensable guide, particularly those involved with ion mobility spectrometry and the use of ion transport coefficients to test and improve ab initio ion-neutral interaction potentials. Established researchers and academics will find in this book a modern companion to the classic references.
PCBs have captured the attention of scientists, journalists and the public for three decades, but during most of that time attention was focused on a small number of the 209 possible chlorobiphenyls. Recent work has implicated many of the forgotten and/or unstudied congeners as neuro-endocrine active and potential developmental toxicants. This interest has created a need for information regarding the `non-dioxin-like' PCBs. The ortho Side of PCBs: Occurrence and Disposition integrates historical information, analytical interpretations, and global concepts with recent comprehensive residue reports and public health concerns. This condensed source of extensive information provides detailed comparisons of comprehensive data in a consistent format. The data will improve the accuracy of concepts regarding the occurrence and disposition of the 60-100 (rather than 6-10) most important congeners. Actual PCB burdens are shown to deviate from average steady-state profiles through sporadic exposures to unique mixtures characteristic of individual dietary sources. The task of accurate hazard characterization and risk assessment can be overwhelming, especially when sporadic changes are considered. Models and relationships are suggested to facilitate the efficient categorization and evaluation of the more important congeners.
To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications. This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys. Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types. Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.
Contemporary Corrections: A Critical Thinking Approach introduces readers to the essential elements of the US corrections system without drowning students in a sea of nonessential information. Unbiased and accessible, the text includes coverage of the history of corrections, alternatives to incarceration, probation/parole, race/ethnicity/gender issues in corrections, re-entry into the community, and more. The authors' unparalleled practical approach, reinforced by contemporary examples, illuminates the role corrections plays in our society. The authors have reinvigorated earlier work with additional content on international comparative data to increase our understanding of how prison officials in other nations have developed different types of responses to the problems that challenge every US correctional administrator, a new chapter on correctional personnel, and an integration of race and ethnicity issues throughout the book. Unrivaled in scope, this book offers undergraduates a concise but comprehensive introduction to corrections with textual materials and assignments designed to encourage students’ critical thinking skills.
This Is a Great Book " is rooted in the belief that having a wide range of "great" books to read is essential to student success as readers inside the classroom ... and beyond. Based on extensive research, this highly readable book explores a wide range of recommended titles that cover a spectrum of developmental stages for readers of chapter books to young adult novels. It presents novels around popular themes and features guest voices that include innovative teachers, librarians, booksellers, and students. Numerous activities and literacy events form the core of this valuable resource. Reproducible pages include response activities, reflection tools, assessment profiles, and inventories for easy classroom use. Committed to nurturing the love of reading, the book invites readers to dig deeper in their understanding and appreciation of books by responding through writing, discussion, the arts, media, and more. Special attention is given to the world of independent leisure reading, where students make choices based on their preferences and tastes. Experienced and new teachers will find fresh ideas and the tools they need to guide students to "great" books that will make a difference in their lives.
Based on extensive research on the features that make children's books appealing and appropriate, this valuable teacher resource offers guidance on selecting books, strategies for specific grade levels, suggestions for extension, and tips for assessment. This teacher-friendly book is organized around the major genres -- traditional literature, picture books, nonfiction, poetry, and multicultural texts -- that will inspire young readers. Throughout the book, teachers will find suggestions for using literature to implement shared reading, reading aloud, and response strategies with emergent, developing, and independent readers.
Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects – that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, standard therapies. The large body of evidence supporting these concepts makes them deserving of further research and well-designed clinical trials. It discusses lipid, cholesterol, glutamine, and glucose metabolisms and their impact on prostate cancer. Additionally, it explains how current established drugs can be repurposed to improve treatment outcomes. The concepts set out in the book, that deal with cancer at the cellular/molecular level, help identify new avenues of research and treatments to pursue that do not affect well-being whilst offer consistent benefits. Since most practicing physicians have not studied basic biochemistry since medical school, each chapter begins with a brief review of the topic to facilitate an understanding of the metabolically-oriented approach to targeting prostate cancer. Conventional treatments are not discussed here since they are covered in textbooks and specialized updates that abound in the medical literature. It is a valuable resource for cancer researchers, oncologists, clinicians and members of biomedical field who want to learn more about prostate cancer metabolism and how to apply recent findings in the field to bedside. - Explains the basic aspects of prostate cancer metabolism, including its biochemistry which has a pivotal role in clinical practice - Discusses new drugs and nutraceuticals with a metabolism-centered approach - Offers practical bedside approach in combination with molecular and biochemical fundamentals to help readers identify and provide the best treatment to their patients
A complete, thorough, and pragmatic guide to clinical assessment, this authoritative book meets a key need for both students and practitioners. T. Mark Harwood, Larry E. Beutler, Gary Groth-Marnat, and their associates describe how to construct a "moving picture" of each patient by integrating data from a variety of sources. Included are detailed, systematic reviews of widely used instruments together with strategies for selecting the best methods for particular referral questions. Readers learn to conduct integrated assessments that take the complexities of the individual personality into account, serve as the basis for developing an effective treatment plan, and facilitate meaningful reporting and client feedback. New to This Edition *Incorporates the latest research findings and assessment/treatment planning tools. *Chapters on the Personality Assessment Inventory and the NEO-PI-R and NEO-PI-3. *A new extended case example runs throughout the chapters. *Critically evaluates the recently published MMPI-2-RF.
About the Book Larry Rodenstein was on the top of his class, graduating Cum Laude in an accelerated prototype program while simultaneously earning both a bachelor’s and master’s of science degree in mechanical engineering, then going to work for Shell Oil. But an untreated bipolar condition led to a psychotic break and sent him spiraling into a street alcoholic, enjoying the nightlife in New Orleans. Up and Down the Ivory Tower discusses the author’s regression to a nervous breakdown and subsequently taking prescribed antipsychotics, which may have affected his genetic makeup and led to his son, Keith, being diagnosed with Autism Spectrum Disorder. When the child was diagnosed with ASD in 1995, the statistic was 1 in 10,000 children being diagnosed with ASD or .1% of births. The CDC is currently indicating that 1 in 44 births or 2.27% of children in 2022 are being born with ASD, a twenty-two-times increase in approximately twenty-six years. Larry Rodenstein states, “I’ve written this book to urge doctors to stop prescribing these antipsychotics. They are moderately affecting our gene pool. I recommend that the medical and health services community explore alternative holistic treatments.” About the Author Larry Rodenstein works at Riverside Community Health. A psycho-social rehabilitation program for people who have had mental health issues integrating them back into the community via employment and/or education. He enjoys flying radio-frequency planes in his spare time.
Thomas Beddoes (1760-1808) lived in ‘decidedly interesting times’ in which established orders in politics and science were challenged by revolutionary new ideas. Enthusiastically participating in the heady atmosphere of Enlightenment debate, Beddoes' career suffered from his radical views on politics and science. Denied a professorship at Oxford, he set up a medical practice in Bristol in 1793. Six years later - with support from a range of leading industrialists and scientists including the Wedgwoods, Erasmus Darwin, James Watt, James Keir and others associated with the Lunar Society - he established a Pneumatic Institution for investigating the therapeutic effects of breathing different kinds of ‘air’ on a wide spectrum of diseases. The treatment of the poor, gratis, was an important part of the Pneumatic Institution and Beddoes, who had long concerned himself with their moral and material well-being, published numerous pamphlets and small books about their education, wretched material circumstances, proper nutrition, and the importance of affordable medical facilities. Beddoes’ democratic political concerns reinforced his belief that chemistry and medicine should co-operate to ameliorate the conditions of the poor. But those concerns also polarized the medical profession and the wider community of academic chemists and physicians, many of whom became mistrustful of Beddoes’ projects due to his radical politics. Highlighting the breadth of Beddoes’ concerns in politics, chemistry, medicine, geology, and education (including the use of toys and models), this book reveals how his reforming and radical zeal were exemplified in every aspect of his public and professional life, and made for a remarkably coherent program of change. He was frequently a contrarian, but not without cause, as becomes apparent once he is viewed in the round, as part of the response to the politics and social pressures of the late Enlightenment.
Here is an invaluable guide to the cruise lines, the ships themselves and their ports of call in the Western and Southern Caribbean, extending from the Bahamas down to Trinidad and even Venezuela. You will have between eight and 10 hours in each cruise port you visit. This guide tells you how to make the most of that time by focusing on the best sights and activities at every stop. For each port, the author provides an over-view description, a detailed map, complete information on how to get around, a "one-day sightseeing tour," both in the port itself and beyond, recreational activities from golf and tennis to hiking and beach-going, shopping, and tours of historical sites.
For two thousand years, theologians have been attempting to explain the Bible’s book of Revelation. The mysterious last plague, also known as the “seventh vial,” was explained to John by the angel of the Lord and documented in two chapters within Revelation. For centuries, it was a fiercely debated topic because it had not happened yet—until September 11, 2001. In a comprehensive and enlightening biblical study, Larry Ammons extracts forty verses from the two chapters and matches them with forty events that took place at the World Trade Center at the beginning of the twenty-first century. Through fact-based evidence and Bible epigraphs, Ammons demonstrates how and why the ancient prophecies have come true and reveals by truth, not coincidence, how ten men were allowed powers as kings for an hour and forever changed the world in the process. The Grace of Sin is a unique presentation of facts that examines the seventh plague in the book of Revelation, compares biblical facts with actual events, and reveals shocking truths.
A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume: Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry Details many of the recent developments in organic chemistry that prepare target molecules Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.
A LIFE LIVING FATE is the journey that we all have to take during our life. It questions if fate or predestination dictates the decisions we make. Once a decision has been made, is it the stepping stone to the next event in our life? The book examines how events are connected to each other through decisions that are made. Planned or coincidence, it’s something that you will have to face the consequences for.
Making your marriage healthy—and making it last—has never been harder. In an age when the pressures on marriage are heavy and divorce is more accepted and easier to obtain, marriages seem to fail as often as they succeed. When you come from a home of divorce, making your own marriage work is even tougher than the norm. Fortunately, in Breaking the Cycle of Divorce, author John Trent, an adult child of divorce himself, gives you the encouragement, insight, and tools you need to beat the odds. Learn how you can, in fact, succeed where your parents failed.
In this provocative volume, experts address the intense relationship between chemical dependency and AIDS. They explore whether some drugs alter the immune system, whether drugs and alcohol play a role in predisposing some people to AIDS, and whether there are neurological, psychiatric, and medical differences between those who get the disease and those who don't. The implicationslegal, moral, and ethicalof AIDS on chemical dependency programs are closely examined.
The Sourcing Solution will help you stay on top of it all by giving you a clear and thorough overview of the new tools for sourcing success. Author Larry Paquette brings his considerable experience to this engaging and accessible guide, designed to give you practical ideas to use in your organization and throughout your entire career."--Jacket.
“I call this book The Intent to Live because great actors don’t seem to be acting, they seem to be actually living.” –Larry Moss, from the Introduction When Oscar-winning actors Helen Hunt and Hilary Swank accepted their Academy Awards, each credited Larry Moss’s guidance as key to their career-making performances. There is a two-year waiting list for his advanced acting classes. But now everyone–professionals and amateurs alike–can discover Moss’s passionate, in-depth teaching. Inviting you to join him in the classroom and onstage, Moss shares the techniques he has developed over thirty years to help actors set their emotions, imagination, and behavior on fire, showing how the hard work of preparation pays off in performances that are spontaneous, fresh, and authentic. From the foundations of script analysis to the nuances of physicalization and sensory work, here are the case studies, exercises, and insights that enable you to connect personally with a script, develop your character from the inside out, overcome fear and inhibition, and master the technical skills required for success in the theater, television, and movies. Far more than a handbook, The Intent to Live is the personal credo of a master teacher. Moss’s respect for actors and love of the actor’s craft enliven every page, together with examples from a wealth of plays and films, both current and classic, and vivid appreciations of great performances. Whether you act for a living or simply want a deeper understanding of acting greatness, The Intent to Live will move, instruct, and inspire you.
Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Asphalt, also known as bitumen, is a semi-solid, solid or viscous liquid produced by the distillation of crude oil during petroleum refining. It has a varied of uses including as paving and roofing materials, in protective coatings to prevent corrosion of metals, in the lining of irrigation canals, water reservoirs, dams, and sea defence works, in adhesives in electrical laminates and as a base for synthetic turf. This publication, part of a series from the International Programme on Chemical Safety, evaluates the effects of asphalts on human health and the environment.
Larry Carbone provides a balanced and reasonable advocacy of animal rights, looking at how to ethically and responsibly conduct biomedical and behavioural research that respects the rights and welfare of all subjects including animals.
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