The easiest and most trusted way to learn the clinical application of pharmacokinetics 5 STAR DOODY'S REVIEW! "This is an important reference that teaches clinically relevant pharmacokinetic dosing and therapeutic drug monitoring tools. This second edition includes updated information on dosing immunosuppressants, as well as dosing concepts in pediatric and hemodialysis patients. The book is intended as an instructive tool in pharmacokinetics for healthcare practitioners who wish to learn these concepts and apply them in their clinical practice. The book satisfies its objectives, outlining important pharmacokinetic concepts in an organized and easy to understand fashion. It is also written by a pharmacist with extensive experience in pharmacokinetics and includes clinically pertinent pearls for individual drugs. This second edition succeeds at providing updated information on pharmacokinetic concepts. The book presents information in a manner that allows readers to teach themselves about pharmacokinetic dosing and to update their knowledge about clinically relevant concepts for the medications. These concepts are critical because medications are far too often dosed without individual patient characteristics (weight, age, concomitant medications) in mind. It is important to individualize dosing based on pharmacokinetic methods, to monitor levels, and to adjust subsequent dosing based on peaks, troughs, renal, and hepatic function." -- Doody's The most current, hands-on book in the field, Applied Clinical Pharmacokinetics gives you clear and useful coverage of drug dosing and drug monitoring that no other text can match. It offers the latest standardized techniques and approaches to patient-specific dosing plus new information on more recent pharmacokinetically monitored drugs. Written by a nationally recognized authority in pharmacokinetics, Applied Clinical Pharmacokinetics provides essential information covered in pharmaceutics, pharmacokinetics, therapeutics, and clinical pharmacy courses. It can be also be used as a clinical refresher to brush up on key concepts and procedures. FEATURES NEW! High-yield sections on dosing strategies in all chapters NEW! Up-to-date, ready-to-use information on monitored drugs Valuable coverage of drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure and patients on dialysis All the information that you need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Tools that simplify learning throughout, such as an introductory chapter on clinical pharmacokinetic and pharmacodynamic concepts, examples of calculations, and problems with answers and explanations at the end of each chapter
The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems throughout the chapter, with a ton of practice problems at the end. Answers for the practice problems are in the back, but not detailed like the sample problems) *Changes in the 3/e includes: *All chapters updated and revised, as needed, including critical new references *Antibiotic individualization and monitoring sections increases use of pharmacodynamic parameters (Cmax/MIC, AUC24/MIC, Time above MIC) in addition to pharmacokinetic parameters to adjust dosages *Anticonvulsants section includes 5 new agents (Fosphenytoin, Lamotrigine, Levetiracetam, Oxcarbazepine, Eslicarbazepine) *Immunosuppressants section includes 1 new agent (Sirolimus), About the Book Text focuses on the latest standardized techniques and approaches to patient-specific dosing and provides up-to-date information on more recently moniotored drugs. Features Clear, useful coverage of drug dosing and drug monitoring Clear and concise summary of pharmacokinetic and pharmacodynamic concepts Practical help with calculations and equations Focus on the latest standardized techniques and approaches to patient-specific dosing Up-to-date information on more recently monitored drugs Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure All the information practitioners need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Full coverage of drugs such as Aminoglycosides, Vancomycin, Digoxin, Phenytoin, Carbamazepine, Theophylline, Cyclosporine, Tacrolimus, and Lithium Student friendly approach to teaching pharmacokinetics--sample problems embedded into the text to allow for students to apply what they are learing. .
New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated
Peterson's Principles of Oral and Maxillofacial Surgery, Third Edition, encompasses a wide range of diverse topics making it a unique text amongst the medical and dental specialties. The purpose of this concise, easy-to-read two-volume text is to provide an authoritative and currently referenced survey of the specialty of Oral and Maxillofacial Surgery. It contains the necessary information for clinicians and is an ideal reference text for preparation for board certification in the specialty.
The underground railroad—with its mysterious signals, secret depots, abolitionist heroes, and slave-hunting villains—has become part of American mythology. But legend has distorted much of this history. Larry Gara shows how pre-Civil War partisan propanda, postwar remininscences by fame-hungry abolitionists, and oral tradition helped foster the popular belief that a powerful secret organization spirited floods of slaves away from the South. In contrast to much popular belief, however, the slaves themselves had active roles in their own escape. They carried out their runs, receiving aid only after they had reached territory where they still faced return. The Liberty Line puts slaves in their rightful position: the center of their struggle for freedom.
Provides comprehensive coverage you need to understand, diagnose, and manage the ever-changing, high-risk clinical problems caused by pediatric infectious diseases.
To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications. This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys. Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types. Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.
The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems throughout the chapter, with a ton of practice problems at the end. Answers for the practice problems are in the back, but not detailed like the sample problems) *Changes in the 3/e includes: *All chapters updated and revised, as needed, including critical new references *Antibiotic individualization and monitoring sections increases use of pharmacodynamic parameters (Cmax/MIC, AUC24/MIC, Time above MIC) in addition to pharmacokinetic parameters to adjust dosages *Anticonvulsants section includes 5 new agents (Fosphenytoin, Lamotrigine, Levetiracetam, Oxcarbazepine, Eslicarbazepine) *Immunosuppressants section includes 1 new agent (Sirolimus), About the Book Text focuses on the latest standardized techniques and approaches to patient-specific dosing and provides up-to-date information on more recently moniotored drugs. Features Clear, useful coverage of drug dosing and drug monitoring Clear and concise summary of pharmacokinetic and pharmacodynamic concepts Practical help with calculations and equations Focus on the latest standardized techniques and approaches to patient-specific dosing Up-to-date information on more recently monitored drugs Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure All the information practitioners need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Full coverage of drugs such as Aminoglycosides, Vancomycin, Digoxin, Phenytoin, Carbamazepine, Theophylline, Cyclosporine, Tacrolimus, and Lithium Student friendly approach to teaching pharmacokinetics--sample problems embedded into the text to allow for students to apply what they are learing. .
The abundance of sulfate-reducing bacteria and archaea (SRBA) is impressive and new isolates are being reported continuously. A few decades ago, only two genera of sulfate-reducing bacteria (SRB) had been identified. As of 2018, 92 genera containing more than 420 species of SRB have been isolated and characterized and there are several species of archaea. This book addresses the development of the research with SRBA and includes historical background of this field. Biochemical characterization of the enzymes, cytochromes and electron carriers involved with dissimilatory sulfate reduction are reviewed and the presence of relevant genes in cultured and uncultured SRBA are assessed using genome analysis. The contributions of transmembrane electron transport complexes as related to cell energetics are discussed. This book highlights the unique cellular and molecular features of the SRBA and discusses the biochemical interactions behind their metabolic capabilities which enable SRBA to grow in extreme environments. Examples are provided to detoxify and alleviate pollution situations, to evaluate mechanisms proposed for corrosion of ferrous metals and to examine the effects of SRB on human and animal hosts.
Characters so real they could walk off the page, virtuoso writing and up-all-night drama."— People From acclaimed novelist Larry Watson, a multigenerational story of the West told through the history of one woman trying to navigate life on her own terms. Edie—smart, self‑assured, beautiful—always worked hard. She worked as a teller at a bank, she worked to save her first marriage, and later, she worked to raise her daughter even as her second marriage came apart. Really, Edie just wanted a good life, but everywhere she turned, her looks defined her. Two brothers fought over her. Her second husband became possessive and jealous. Her daughter resented her. And now, as a grandmother, Edie finds herself harassed by a younger man. It’s been a lifetime of proving that she is allowed to exist in her own sphere. The Lives of Edie Pritchard tells the story of one woman just trying to be herself, even as multiple men attempt to categorize and own her. Triumphant, engaging, and perceptive, Watson’s novel examines a woman both aware of her power and constrained by it, and probes the way perceptions of someone in a small town can shape a life through the decades.
The premier reference on obstetrics practice for nearly a century, the new Twenty-Second Edition is the ideal text for anyone who provides maternal and fetal health care. Now offering state-of-the-art diagnostic ultrasound images throughout, Williams Obstetrics maintains its strong, evidence-based approach. Rigorously referenced and clearly written, Williams' hallmarks are thoroughness, scientific basis, and practical applicability for the obstetrician at the bedside. The world-renowned management guidelines and recommendations have been thoroughly updated through analysis of the scientific literature. This is the only book providing coverage sufficient for the needs of all practicing physicians and residents in board preparation and training. New features include: • NEW STATE-OF-THE-ART ULTRASOUND IMAGES integrated throughout for easier diagnostic confirmation • COMPLETELY REVISED BASIC SCIENCE SECTIONS for greater usefulness in daily practice • NEW CHAPTERS on hot topics: prior cesarean delivery; gestational trophoblastic disease; obesity; thromboembolism; and liver disease • THOROUGHLY UPDATED CHAPTERS on evolving areas: fetal development; placental disorders; and infectious diseases • UPDATED GUIDELINES and STANDARDS of CARE reflecting the current scope of practice
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