Cell surface membranes have long been characterized as two-dimensional fluids whose mobile components are randomized by diffusion in the plane of the membrane bilayer. Recent research has indicated that cell surface membranes are highly organized and ordered and that important functional units of membranes appear as arrays of interacting molecules rather than as single, freely diffusing molecules. Mobility and Proximity in Biological Membranes provides an overview of the results obtained from biophysical methods for probing the organization of cell surface membranes. These results are presented in the context of detailed treatments of the theory and the technical demands of each of the methods. The book describes a versatile and easily applied mode for investigating molecular proximities in plasma membranes in a flow cytometer. Its analysis of lipid fluidity and viscosity of membranes and the rotational mobility of proteins offers intimate insight into the physical chemistry of biological membranes. The electrophysiology of lymphocytes is presented with focus on its importance in different diseases. New techniques are described, and new data, new possibilities, and future trends are presented by world experts. This book's chapters can serve both as guides to the existing literature and as starting points for new experiments and approaches associated with problems in membrane function.
The renowned German reference work The Handbuch der Zoologie/Handbook of Zoology was founded in the 1920's by Professor Willi Kükenthal in Berlin and treated the complete animal kingdom from single cell organisms to mammals in eight thematic volumes: Volume I Protozoa, Porifera, Colenteratea, Mesozoa (1925); Volume II Worms (1933/34); Volume III Arthropoda ex. Insecta (1927/1932); Volume IV Arthopoda: Insecta; Volume V Solenogastres, Mollusca, Echinoderma (1925); Volume VI Pisces / Amphibia (1930); Volume VII Reptilia / Aves (1931); Volume VIII Mammalia. The Volumes Insecta (Eds. N.P. Kristensen, R.G. Beutel) and Mammalia (Eds. M.S. Fischer, H. Schliemann) continued publication into the present with the most recent contributions in English language. Covering nearly 100 years of zoological research, the Handbook of Zoology represents a vast store of knowledge. But with the speed of scientific discovery in the past decades, a new edition of the Handbook in a new form is required. Beginning in 2010 the Handbook of Zoology will be restructured and offered additionally as a database (Zoology Online) which can be easily searched and rapidly updated. The eight thematic volumes will be replaced with smaller and more flexible groupings that reflect the current state of phylogenetic knowledge. Faster publication times through online-prepublication, reference linking, forward linking and multimedia presentations will make the Handbook of Zoology highly attractive to both authors and users. Aims and Scope The Handbook of Zoology aims to provide an in depth treatment of the entire animal kingdom from the lower invertebrates to the mammals. It publishes comprehensive overviews on animal systematics and morphology as well as extensive coverage of physiology, behaviour, ecology and applied aspects of zoological research. Volumes in progress include Nemathelminthes and Gnathifera, Annelida, Mollusca, Arthropoda, Arthropoda: Insecta, and Mammalia. Although our knowledge regarding many taxonomic groups has grown enormously over the last decades, it is still the ambition of the Handbook to be comprehensive in the sense that text and references together provide a solid basis for further research. Editors and authors seek a balance between describing species richness and diversity, explaining the importance of certain groups in a phylogenetic context and presenting a review of available knowledge and up-to-date reference literature. New contributions to the series present the combined effort of an international team of editors and authors, entirely published in English and explicitly addressing the international scientific community.
Learn the basic techniques every successful playwright knows! Amid the hundreds of "how-to" books out there, there have been very few which attempted to analyze the mysteries of play construction. Lajos Egri's classic, The Art of Dramatic Writing, does just that, with instruction that can be applied equally well to a short story, novel, or screenplay. Examining a play from the inside out, Egri starts with the heart of any drama: its characters. All good dramatic writing hinges on people and their relationships, which serve to move the story forward and give it life, as well as an understanding of human motives—why people act the way that they do. Using examples from everything from William Shakespeare's Romeo and Juliet to Henrik Ibsen's A Doll's House, Egri shows how it is essential for the author to have a basic premise—a thesis, demonstrated in terms of human behavior—and to develop the dramatic conflict on the basis of that behavior. Using Egri's ABCs of premise, character, and conflict, The Art of Dramatic Writing is a direct, jargon-free approach to the problem of achieving truth in writing.
This book showcases powerful new hybrid methods that combine numerical and symbolic algorithms. Hybrid algorithm research is currently one of the most promising directions in the context of geosciences mathematics and computer mathematics in general. One important topic addressed here with a broad range of applications is the solution of multivariate polynomial systems by means of resultants and Groebner bases. But that’s barely the beginning, as the authors proceed to discuss genetic algorithms, integer programming, symbolic regression, parallel computing, and many other topics. The book is strictly goal-oriented, focusing on the solution of fundamental problems in the geosciences, such as positioning and point cloud problems. As such, at no point does it discuss purely theoretical mathematics. "The book delivers hybrid symbolic-numeric solutions, which are a large and growing area at the boundary of mathematics and computer science." Dr. Daniel Li chtbau
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