This classification is based primarily on the microscopic characteris tics of tumours. It is therefore concerned with the identification of cell types and histological patterns as seen by conventional light micro scopy. In general, time-honoured terms have been retained. Syn onyms are listed only if they have been widely used or if they are con sidered to be important for understanding the disease process. In such cases, the preferred term is given first, followed by the synonym in parentheses. The individuality of a tumour manifests itself principally in its histological appearance and the extent of spread at the time of diag nosis. This volume is concerned only with the histological classific ation of tumours. Anatomical extent or staging is covered in the TNM Classification.! The histological classification of a tumour de pends on two main parameters, typing and grading, and a number of additional parameters which may apply to selected examples. Histological Typing This divides tumours of a given organ into different types according to their direction of differentiation. Although this may frequently in dicate the underlying histogenesis of the tumour, it may be difficult or impossible to identify the cell of origin. Note is taken of the structure and function of cell types, as well as the overall growth pattern of the tumour, with the aim of matching these features to those of a normal tissue found in the same organ.
This is the revised edition of the WHO histological classification of oesophageal and gastric tumours. It reflects the important changes that haveoccurred since the first edition in the fields of lymphomas, endocrine tumours and the dysplasias as well as adding a number of newly describedentities. it sets the international standard for the next decade.
A comprehensive introduction to one of the most common psychiatric disorders, a condition that results in intrusive, irrational thoughts and/or repetitive, illogical physical or mental actions. Titles in this Health and Psychology Sourcebooks series address psychological, physical, or environmental conditions that threaten human health and wellbeing. This book presents a comprehensive overview of OCD—one of the five most common psychiatric disorders. Obsessions range from those associated with contamination, safety, and order or symmetry to scrupulosity, or the need the do the "right" thing. Compulsions range from counting, touching, and tapping to excessive cleaning/washing, arranging, or even hoarding. Written by a therapist among the most experienced in the world in dealing with this disorder, this book covers the incidence, symptoms, diagnosis, history, development, and causes, as well as the effects and costs of OCD. It also addresses theory, research, and treatments and offers insight into and case studies illustrating how the disorder displays in society, at work, and in relationships. A glossary of terms, suggested further readings, and resource websites and organizations listing are included.
In this work I endeavour to explain the morphological changes in diseases of the human ear, nose, larynx and pharynx. Efficient ENT practice, like that in other surgical specialties, relies on close collaboration between surgeon and pathologist through the medium of biopsies. Accordingly much of the present volume emphasizes diagnostic surgical pathology. The role of the pathologist is, however, a broader one-in otolaryngology as in other specialties-contributing as well to an understanding of the disease processes. For this pur pose autopsy study is important and nowhere more so than in the disease of the inner ear, an area which has been developed mainly by otologists, but neglected by pathologists. It is hoped that, by displaying the interest and potential for development of such fields, this book may stimulate some pathologists to work in them. I kept in mind while writing the possibility that it might also be useful to ENT clinicians as a review of the pathology of their specialty.
Access all of the latest advances in thyroid disorder management on your favorite eReader with Endocrinology: Adult and Pediatric: The Thyroid Gland! Brought to you by the same leading endocrinologists responsible for the highly acclaimed two-volume Endocrinology clinical reference, this new thyroid disorder eBook enables you to give your patients the benefit of today's best know-how. - Stay abreast of the newest knowledge and advances in thyroid disease, including the use of thyroglobulin assays and ultrasound vs. isotope scanning in thyroid cancer; the latest understanding of Graves' eye disease; the use of I-131 in management of multinodular goiter; T4 transport defects causing thyroid hormone resistance; best practices in management of thyroid disease during pregnancy; and much more. - Benefit from authoritative guidance on thyroid testing. - Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. - Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and DeGroot, the go-to clinical reference for endocrinologists worldwide. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.
Over the past 40 years, ERCP has become an effective therapeutic modality with diagnostic purposes that are continually improved.. The 3rd Edition of this practical reference helps you make the most of today's endoscopic retrograde cholangiopancreatography in your practice. You'll find authoritative, highly illustrated guidance on every aspect of ERCP, including coverage of the latest techniques. - Clearly depicts each step of ERCP procedures in dozens of step-by-step videos, including Needle Knife Sphincterotomy, Biliary Sphincterotomy, Cannulation, and Fistulotomy. - Provides clear guidelines on when and when not to perform ERCP. - Features superb, full-color images, and a wealth of illustrative diagrams. - Includes new chapters that cover duodenoscope reprocessing; endomicrocopy; EUS-guided endotherapy related to pancreatobiliary disorders; and CT and MRCP related to pancreatobiliary disorders. - Contains updated information on radiofrequency ablation for cancer, percutaneous vs. endoscopic drainage, scope cleaning practices, and pancreatic necrosis. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. This reference is optimally designed to help you succeed in your demanding practice and ensure the best possible outcomes for every patient. Overcome virtually any clinical challenge with detailed, expert coverage of every area of endocrinology, authored by hundreds of leading luminaries in the field. Provide state-of-the-art care with comprehensive updates on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors ... brand-new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis ... expanded coverage of sports performance, including testosterone, androgen research, and bone growth and deterioration ... and the newest discoveries in genetics and how they affect patient care. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information more quickly, while still getting the complete coverage you expect.
Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Part of the in-depth and practical Pattern Recognition series, Practical Pulmonary Pathology, 3rd Edition, helps you accurately identify and interpret neoplastic and non-neoplastic diseases of the lungs by using a pattern-based approach. Leading diagnosticians in pulmonary pathology guide you from a histological pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Superb, full-color illustrations capture key pathological patterns for a full range of common and rare conditions, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance. A user-friendly design color-codes patterns to specific entities, and key points are summarized in tables, charts, and graphs so you can quickly and easily find what you are looking for. Sweeping content updates keep you at the forefront of recent findings regarding pulmonary hypertension, pediatric lung disease, and all major neoplastic and non-neoplastic diseases of the lung. An online virtual microscope provides access to more than 150 digital slides. A new chapter on Pulmonary Function Testing for Pathologists brings you up to date with relevant aspects of these key tests. Improved pattern call-outs are now linked directly within the chapter, reinforcing the patterns for more efficient and complete understanding. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
This is the revised edition of the WHO histological classification of oesophageal and gastric tumours. It reflects the important changes that haveoccurred since the first edition in the fields of lymphomas, endocrine tumours and the dysplasias as well as adding a number of newly describedentities. it sets the international standard for the next decade.
This classification is based primarily on the microscopic characteris tics of tumours. It is therefore concerned with the identification of cell types and histological patterns as seen by conventional light micro scopy. In general, time-honoured terms have been retained. Syn onyms are listed only if they have been widely used or if they are con sidered to be important for understanding the disease process. In such cases, the preferred term is given first, followed by the synonym in parentheses. The individuality of a tumour manifests itself principally in its histological appearance and the extent of spread at the time of diag nosis. This volume is concerned only with the histological classific ation of tumours. Anatomical extent or staging is covered in the TNM Classification.! The histological classification of a tumour de pends on two main parameters, typing and grading, and a number of additional parameters which may apply to selected examples. Histological Typing This divides tumours of a given organ into different types according to their direction of differentiation. Although this may frequently in dicate the underlying histogenesis of the tumour, it may be difficult or impossible to identify the cell of origin. Note is taken of the structure and function of cell types, as well as the overall growth pattern of the tumour, with the aim of matching these features to those of a normal tissue found in the same organ.
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