Has the neuromuscular junction been over-exposed or is it perhaps already a closed book? I asked myself this at a recent International Congress when an American colleague complained that the Journal of Physiology had articles on nothing but the neuromuscular junction, while another colleague asked why I was editing a volume on a subject about which everything was already known. It is worrying to think that these views may be shared by other people. I hope that this volume will convince my two colleagues and other readers that the neuromuscular junction is very much alive and continues to attract the interest of many workers from a variety of fields; strange as it may seem, the synapse between a motor nerve ending and muscle fibre, with its relatively simple architecture, is one of the most inter esting sites in the body-I do hope we have done it justice. The various chapters of this volume present a cross section of knowledge as viewed by a group of 13 individuals, actively engaged in research. Multi-author volumes such as this are frequently criticised on the grounds that chapters or sec tions overlap. I believe that such criticium is only valid where the overlap is repetitious. Where it results in the reader having available discussions of material from differing stand-points, overlap becomes a valuable feature of this type of publication.
This authoritative volume provides a comprehensive survey of the pathology of diseases of the nervous system. The fifth edition is a thorough revision of the work, reflecting significant advances in the field while retaining established facts in a useful and accessible form for all those involved in the study and treatment of neurological disease. The editors have gathered authoritative chapters from an impressive array of experts. A number of new contributors have radically revised or rewritten chapters, some of which present information not available elsewhere. This encyclopedic work describes the recent progress in neuropathology that has been influenced and Pnhanced by new techniques, such as the accurate identification and localization of components of the nervous system achieved by immunohistochemistry. The revolutionary improvements that have taken place in the understanding of neurotransmitters, brain damage and nutritional and toxic disorders are all reflected in this revised edition along with important developments in molecular genetics. The effect of AIDS and other immunological disorders on the nervous system is also covered. Thoroughly updated and extensively illustrated, Greenfield's Neuropathology remains a classic reference work.
Has the neuromuscular junction been over-exposed or is it perhaps already a closed book? I asked myself this at a recent International Congress when an American colleague complained that the Journal of Physiology had articles on nothing but the neuromuscular junction, while another colleague asked why I was editing a volume on a subject about which everything was already known. It is worrying to think that these views may be shared by other people. I hope that this volume will convince my two colleagues and other readers that the neuromuscular junction is very much alive and continues to attract the interest of many workers from a variety of fields; strange as it may seem, the synapse between a motor nerve ending and muscle fibre, with its relatively simple architecture, is one of the most inter esting sites in the body-I do hope we have done it justice. The various chapters of this volume present a cross section of knowledge as viewed by a group of 13 individuals, actively engaged in research. Multi-author volumes such as this are frequently criticised on the grounds that chapters or sec tions overlap. I believe that such criticium is only valid where the overlap is repetitious. Where it results in the reader having available discussions of material from differing stand-points, overlap becomes a valuable feature of this type of publication.
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