Essex is nestled on the Atlantic coast within beautifully preserved hills, forest, fields, and wetlands--but the serene landscape belies the town's rich history. According to tradition, the first Essex boat was built in an attic around 1660. Eventually, this shipbuilding industry would create a thriving town as it developed into one of the largest producers of fishing schooners in the country. By its incorporation in 1819, Essex was a renowned community of fishing, farming, shipbuilding, and other industries. Over time, Essex became the birthplace of the fried clam, sent a native son to the baseball major leagues, acquired a Paul Revere church bell, and raised a barn that is now the oldest still in use in America. With a newly gathered collection of vintage images, Essex reveals a microcosm of American culture and growth, telling the story of leading patriots, entrepreneurs, Civil War heroes, and hardworking everyday citizens.
Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. - Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders - Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals - Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders
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