Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. - Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine - Focuses on how materials of structures can be designed to be resistant while promoting viable grafts - Contains major tissue types that are covered with a strategy for each material and structure
Among the things that can occupy the human mind positively and arouse curiousity is research. A sound research project can keep a researcher happily spellbound for years, and can also give rise to many projects which in return might initiate development, and create employment. It can equally reduce crime wave, or chase away ignorance in our youths and so on in a given society or beyond. This book therefore is an eye-opener into the research world and is based on the findings of well-known researchers, likewise those that are not known, but who have contributed positively in particular moments. The book is made up of nine chapters. Chapter one highlights Giants in the field of research such as. Nicolaus Copernicus, Galileo. Bacon, Sir Isaac Newton (1642-1727) Albert Einstein (1879-1955) and others. Chapter two suggests places from where researchers can be observed or groomed. Chapter three handles the soft skills or “who you are”, that are very necessary to succeed as a researcher. Chapter four, chapter five, chapter six, chapter seven, chapter eight and chapter nine examine hard skills or “what you should know” in order to be a research giant, (the definition of research, research paradigms, elements of research paradigms, research approaches, research designs, and research methodologies). This book is appropriate as a text for minds-building and awareness creation in the world of research. It is intended for students, teachers and youths.
This book provides a comprehensive and up-to-date listing of the sources of immunochemicals for use in laboratory-based specialties such as Histopathology. Much more than just a catalogue of these chemicals, it includes specific technical details on the application and specificities of antisera, common pitfalls in use and how to avoid them, an aspect not covered in other similar texts.
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