Krzysztof Krawczyk's Books

Basic and Advanced Calculations for the Solution of Problems in the Chemical Industry

By: Krzysztof Schmidt-Szałowski,Krzysztof Krawczyk,Jan Petryk,Jan Sentek,Ewa Iwanek

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Basic and Advanced Calculations for the Solution of Problems in the Chemical Industry

By: Krzysztof Schmidt-Szałowski,Krzysztof Krawczyk,Jan Petryk,Jan Sentek,Ewa Iwanek

The book guides the reader through basic and advanced calculations of key parameters in industrial processes. It is intended for anyone who wishes to improve his or her skills in solving real-life calculations pertaining to large-scale technological processes such as ammonia synthesis, sulphuric acid production, nitric acid production, etc. The exercises are supplied with answers to guide the reader through the solutions found in the chemical industry today. The unique aspect of this book is that it provides a hands-on guide to solving industrially relevant problems in currently existing installations with recycle-loops, cascades of reactors, etc. In short: the book is a collection of all of the most important calculations needed in the chemical industry today.

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Page Count

374

Publisher

Cambridge Scholars Publishing

Published Date

ISBN 10

152752521X

ISBN 13

9781527525214

System Engineering Approach to Planning Anticancer Therapies

By: Andrzej Świerniak,Marek Kimmel,Jaroslaw Smieja,Krzysztof Puszynski,Krzysztof Psiuk-Maksymowicz

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System Engineering Approach to Planning Anticancer Therapies

By: Andrzej Świerniak,Marek Kimmel,Jaroslaw Smieja,Krzysztof Puszynski,Krzysztof Psiuk-Maksymowicz

This book focuses on the analysis of cancer dynamics and the mathematically based synthesis of anticancer therapy. It summarizes the current state-of-the-art in this field and clarifies common misconceptions about mathematical modeling in cancer. Additionally, it encourages closer cooperation between engineers, physicians and mathematicians by showing the clear benefits of this without stating unrealistic goals. Development of therapy protocols is realized from an engineering point of view, such as the search for a solution to a specific control-optimization problem. Since in the case of cancer patients, consecutive measurements providing information about the current state of the disease are not available, the control laws are derived for an open loop structure. Different forms of therapy are incorporated into the models, from chemotherapy and antiangiogenic therapy to immunotherapy and gene therapy, but the class of models introduced is broad enough to incorporate other forms of therapy as well. The book begins with an analysis of cell cycle control, moving on to control effects on cell population and structured models and finally the signaling pathways involved in carcinogenesis and their influence on therapy outcome. It also discusses the incorporation of intracellular processes using signaling pathway models, since the successful treatment of cancer based on analysis of intracellular processes, might soon be a reality. It brings together various aspects of modeling anticancer therapies, which until now have been distributed over a wide range of literature. Written for researchers and graduate students interested in the use of mathematical and engineering tools in biomedicine with special emphasis on applications in cancer diagnosis and treatment, this self-contained book can be easily understood with only a minimal basic knowledge of control and system engineering methods as well as the biology of cancer. Its interdisciplinary character and the authors’ extensive experience in cooperating with clinicians and biologists make it interesting reading for researchers from control and system engineering looking for applications of their knowledge. Systems and molecular biologists as well as clinicians will also find new inspiration for their research.

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