Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDAÆs Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book will be an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers.
Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDAÆs Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book will be an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers.
**Selected for Doody's Core Titles® 2024 in Orthopedics** Gain a strong foundation in the field of orthotics and prosthetics! Orthotics and Prosthetics in Rehabilitation, 4th Edition is a clear, comprehensive, one-stop resource for clinically relevant rehabilitation information and application. Divided into three sections, this text gives you a foundation in orthotics and prosthetics, clinical applications when working with typical and special populations, and an overview of amputation and prosthetic limbs. This edition has been updated with coverage of the latest technology and materials in the field, new evidence on effectiveness and efficacy of interventions and cognitive workload associated usage along with enhanced color photographs and case studies - it's a great resource for students and rehabilitation professionals alike. - Comprehensive coverage addresses rehabilitation in a variety of environments, including acute care, long-term care and home health care, and outpatient settings. - Book organized into three parts corresponding with typical patient problems and clinical decision-making. - The latest evidence-based research throughout text help you learn clinical-decision making skills. - Case studies present real-life scenarios that demonstrate how key concepts apply to clinical decision-making and evidence-based practice. - World Health Organization disablement model (ICF) incorporated to help you learn how to match patient's limitations with the best clinical treatment. - Multidisciplinary approach in a variety of settings demonstrates how physical therapists can work with the rest of the healthcare team to provide high quality care in orthotic/prosthetic rehabilitation. - The latest equipment and technology throughout text addresses the latest options in prosthetics and orthotics rehabilitation - Authoritative information from the Guide to Physical Therapist Practice, 2nd Edition is incorporated throughout. - A wealth of tables and boxes highlight vital information for quick reference and ease of use. - NEW! Color photographs improve visual appeal and facilitates learning. - NEW! Increased evidence-based content includes updated citations; coverage of new technology such as microprocessors, microcontrollers, and integrated load cells; new evidence on the effectiveness and efficacy of interventions; and new evidence on cognitive workload usage. - NEW! Authors Kevin K Chui, PT, DPT, PhD, GCS, OCS, CEEAA, FAAOMPT and Sheng-Che (Steven) Yen, PT, PhD add their expertise to an already impressive list of contributors.
This book illustrates the cyclical pattern in the kinds of dilemmas that confront political leaders and, in particular, disjunctive political leaders affiliated with vulnerable political regimes. The volume covers three major episodes in disjunction: the interwar crisis between 1923 and 1940, afflicting Stanley Baldwin, Ramsay MacDonald and Neville Chamberlain; the collapse of Keynesian welfarism between 1970 and 1979, dealt with by Edward Heath, Harold Wilson and James Callaghan; and the ongoing crisis of neoliberalism beginning in 2008, affecting Gordon Brown, David Cameron and Theresa May. Based on this series of case studies of disjunctive prime ministers, the authors conclude that effective disjunctive leadership is premised on judicious use of the prime ministerial toolkit in terms of deciding whether, when and where to act, effective diagnostic and choice framing, and the ability to manage both crises and regimes.
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