Biochemistry of Halogenated Organic Compounds has been written as a general reference source for researchers in several related areas, including organic chemists, medicinal chemists, pharmacologists, toxicologists, and medical researchers. The development of halogenated compounds as medicinal agents and pharmacological tools and the fascinating biochemi cal processes that have been discovered and studied using these analogues have generated extremely active areas of research and an enormous volume of literature. Thus, halogenated organic compounds pervade every aspect of biochemistry, a fact made apparent by the numerous reviews and monographs available on individual topics-halogenated nucleosides, halogenated carbohydrates, and so forth. Given the quantity of material already written on these topics, some of which material is quite current, it might be asked whether a one-volume review of these subjects is useful, or possible. Having now completed this work, I feel the answer to both questions is an emphatic yes. There are fascinating stories to be related in each area, and, where appropriate, I have attempted to develop these topics . from a historical perspective. For example, the discovery of the anticancer activity of fluorouracil, the unraveling of the several mechanisms of its action, and the development of a host of later generations of anticancer and antiviral agents based on the parent fluoro-, iodo-, bromo-, and trifluoromethylpyrimidines were, and are, contributions of major magnitude to medical science.
Completely revised to reflect recent, rapid changes in the field of interventional radiology (IR), Image-Guided Interventions, 3rd Edition, offers comprehensive, narrative coverage of vascular and nonvascular interventional imaging—ideal for IR subspecialists as well as residents and fellows in IR. This award-winning title provides clear guidance from global experts, helping you formulate effective treatment strategies, communicate with patients, avoid complications, and put today's newest technology to work in your practice. - Offers step-by-step instructions on a comprehensive range of image-guided intervention techniques, including discussions of equipment, contrast agents, pharmacologic agents, antiplatelet agents, and classic signs, as well as detailed protocols, algorithms, and SIR guidelines. - Includes new chapters on Patient Preparation, Prostate Artery Embolization, Management of Acute Aortic Syndrome, Percutaneous Arterial Venous Fistula Creation, Lymphatic Interventions, Spinal and Paraspinal Nerve Blocks, and more. - Employs a newly streamlined format with shorter, more digestible chapters for quicker reference. - Integrates new patient care and communication tips throughout to address recent changes in practice. - Highlights indications and contraindications for interventional procedures, and provides tables listing the materials and instruments required for each. - Features more than 2,300 state-of-the-art images demonstrating IR procedures, full-color illustrations of anatomical structures and landmarks, and video demonstrations online. - 2014 BMA Medical Book Awards Highly Commended in Radiology category!
The book “Big Clifty, Star Route” explores a year in the life of “Bud,” a ten-year-old boy in the small rural community of Limp, Kentucky. The story begins with several adventures brought on by a massive January snowstorm and builds to a climax of an unexpected Christmas experience. Bud struggles to understand his father “Pap,” who is significantly older, and who adheres to a different faith. Dewey Hodge, who owns the local country store, becomes a father figure for Bud. Bud collects pop bottles to buy his dream pocketknife and meets a new friend, Claire Marie. They develop a childhood romance with unexpected consequences as Bud discovers his own identity. Along the way, Bud learns valuable life lessons including hard work, honesty, consequences, and his place in God’s creation.
Explains steps that parents can take to help their child develop talent in any activity that has sparked his or her interest. Nurturing Children's Talents: A Guide for Parents is a book for all parents. That's because talent is made, not born, and parents are in prime position to help children discover and develop talent, whether the talent domain is archery, baton twirling, chess, or zoology. Moreover, talent development is a continuum along which all children can grow. Carnegie Hall might be the destination for some while community band is for others. Meanwhile, most parents are eager to help their children traverse a talent path but don't know how . . . until now. Nurturing Children's Talents offers parents insights and step-by-step plans to help children reach their potential. These recommendations stem from author Kenneth A. Kiewra's personal experience raising a chess champion and his extensive research interviewing talented performers—including national, world, and Olympic champions—and their parents, across many domains.
Lange is a Springer author of other successful books. This is the first book that emphasizes the applications of optimization to statistics. The emphasis on statistical applications will be especially appealing to graduate students of statistics and biostatistics.
Full species accounts for all frogs north of Mexico make this the amphibian book of the decade. Winner of the Wildlife Society Outstanding Edited Book of the Wildlife Society, ALA Award for Outstanding Reference of the American Library Association, CHOICE Outstanding Academic Title of the Choice ACRL With many frog populations declining or disappearing and developmental malformations and disease afflicting others, scientists, conservationists, and concerned citizens need up-to-date, accurate information. Frogs of the United States and Canada is a comprehensive resource for those trying to protect amphibians as well as for researchers and wildlife managers who study biodiversity. From acrobatic tree frogs to terrestrial toads, C. Kenneth Dodd Jr. offers an unparalleled synthesis of the biology, behavior, and conservation of frogs in North America. This two-volume, fully referenced resource provides color photographs and range maps for 106 native and nonindigenous species and includes detailed information on - past and present distribution - life history and demography - reproduction and diet - landscape ecology and evolution - diseases, parasites, and threats from toxic substances - conservation and management
Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. - Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. - Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics - Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. - Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
In a world of accelerating unending change, perpetual surveillance, and increasing connectivity, conflict has become ever more complex. Wars are no longer limited to the traditional military conflict domains—land, sea, air; even space and cyber space. The new battlefield will be the cognitive domain and the new conflict a larger contest for power; a contest for cognitive superiority. Written by experts in military operations research and neuropsychology, this book introduces the concept of cognitive superiority and provides the keys to succeeding within a complex matrix where the only rules are the laws of physics, access to information, and the boundaries of cognition. The book describes the adversarial environment and how it interacts with the ongoing, accelerating change that we are experiencing, irrespective of adversaries. It talks about the ascendant power of information access, pervasive surveillance, personalized persuasion, and emerging new forms of cognition. It profiles salient technologies and science, including persuasion science, artificial intelligence and machine learning (AI/ML), surveillance technologies, complex adaptive systems, network science, directed human modification, and biosecurity. Readers will learn about human and machine cognition, what makes it tick, and why and how we and our technologies are vulnerable. Following in the tradition of Sun-Tsu and von Clausewitz, this book writes a new chapter in the study of warfare and strategy. It is written for those who lead, aspire to leadership, and those who teach or persuade, especially in the fields of political science, military science, computer science, and business.
- NEW! 15 all-new chapters bring you the most current clinical information on recent advances in the science and practice of oral and maxillofacial surgery. ¦ NEW! Cosmetic Surgery section covers the evaluation of the aging face, forehead/blepharoplasty, facelift/neck, rhinoplasty, and non-invasive cosmetic procedures. ¦ NEW! Updated Secrets® two-color design highlights questions, tables, boxes, and bulleted lists so you can find information more easily. FIFTEEN CHAPTERS Chapter 9: Anesthesia for Diffi cult Patients Chapter 13: Introduction to Mechanical Ventilation and ICU Care Chapter 24: Wound Healing Chapter 29: Diagnosis and Management of Dentoalveolar Injuries Chapter 35: Craniofacial Syndromes Chapter 36: Oromandibular Dysostosis Chapter 40: Distraction Osteogenesis Chapter 45: Cancer of the Oral Cavity Chapter 47: Vascular Anomalies Chapter 48: Osteoradionecrosis/Osteonecrosis of the Jaws Chapter 49: Neck Mass Chapter 50: Bone Grafting to Facilitate Dental Implant Placement Chapter 51: Local and Regional Flaps Chapter 52: Reconstruction of the Facial Subunits Chapter 53: Microvascular Surgery CHAPTERS DEALING WITH COSMETIC SURGERY Chapter 54: Evaluation of the Aging Face Chapter 55: Cosmetic Blepharoplasty Chapter 56: Rhytidectomy Chapter 57: Rhinoplasty Chapter 58: Minimal-Invasive Cosmetic Procedures
This essential, updated reference provides quick-access to names, addresses, telephone and FAX numbers for denominational leaders, headquarters, agencies, and regional headquarters, as well as current statistical data for churches throughout all of the United States and Canada. Includes information on Bible colleges and seminaries, religious periodicals, trends, and more. Illustrations.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
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