Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.
While competitive natural selection is widely assumed to be evolution’s prime mover, Weiss shows how life generally works on the basis of cooperation. He reveals that focus on competition and cooperation is largely an artifact of compression of time—a distortion that dissolves when life is viewed from developmental and evolutionary time scales.
In this book the authors draw on what is known, largely from recent research, about the nature of genes and cells, the genetics of development and animal and plant body plans, intra- and interorganismal communication, sensation and perception, to propose that a few basic generalizations, along with the modified application of the classical evolutionary theory, can provide a broader theoretical understanding of genes, evolution, and the diverse and complex nature of living organisms.
Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
The category of learning disabilities continues to be among the most contentious in special education. Much of the debate and dissent emanates from a lack of understanding about its basic nature. The failure to evolve a comprehensive and unified perspective about the nature of learning disabilities has resulted in the concept being lost. The loss is best illustrated through the failure to answer this seemingly simple question: What is a learning disability? Using historical, empirical, theoretical, conceptual, and philosophical analyses, this volume explores a number of problems and issues facing the field of learning disabilities. The chapters cover historical influences, definitional problems, primary characteristics, assessment practices, theoretical development, major themes, research and measurement models, and long-term outcomes. The goal is to explicate the nature of learning disabilities by analyzing what it was supposed to be, what it has become, and what it might be. A predominant theme running through this text is the necessity for the field of learning disabilities to regain integrity by recapturing its essence.
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
Many today find the Old Testament a closed book. The cultural issues seem insurmountable and we are easily baffled by that which seems obscure. Furthermore, without knowledge of the ancient culture we can easily impose our own culture on the text, potentially distorting it. This series invites you to enter the Old Testament with a company of guides, experts that will give new insights into these cherished writings. Features include • Over 2000 photographs, drawings, maps, diagrams and charts provide a visual feast that breathes fresh life into the text. • Passage-by-passage commentary presents archaeological findings, historical explanations, geographic insights, notes on manners and customs, and more. • Analysis into the literature of the ancient Near East will open your eyes to new depths of understanding both familiar and unfamiliar passages. • Written by an international team of 30 specialists, all top scholars in background studies.
First published in 1986. The primary purpose of this book is to provide information about the use of medication for several childhood disorders that require long-term treatment. It is the author’s expectation that this information will allow caregivers to make better decisions about the use of medication. This title also examines the importance of evaluating various aspects when medicating a child, including their characteristics, their family situation, and school setting.
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology
Answer patients’questions about botanical supplements quickly and easily!This informative book is a compendium of detailed scientific research on 34 of the most popular dietary supplements used in North America and Europe. Its coverage of pharmacological studies on the main medicinal plants used in clinical practice and sold in pharmacies in the Western world is more extensive than any other publication of monographic reviews available. The way Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition. is organized (standardized topic formats are used in each monograph) makes it easy for you to locate relevant information quickly and to compare corresponding sections between different entries. This book is an invaluable tool for pharmacists, physicians, and other health care professionals who need detailed, scientifically accurate information on appropriate use, safety, dosages, and similar issues related to botanical dietary supplements.Each entry in Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition. covers botanical data (classification and nomenclature, common names, geographic occurrence, and botanical characteristics), plus: history and traditional uses chemistry therapeutic applications pre-clinical studies clinical studies recommended dosages safety profiles (including toxicology) side effects and contraindications drug interactions and special precautions safety recommendations during pregnancy and lactation This extensively referenced volume includes appendixes with information on the major provisions of DSHEA (the Dietary Supplement Health and Education Act of 1994) and on the criteria and procedures for assessing the quality of botanical products.
The world’s leading resource for to diagnosing and treating any injury—quickly, safely, and effectively Doody's Core Titles for 2023! Unparalleled in its breadth and depth of expertly crafted content, Trauma takes you through the full range of injuries you are likely to encounter. With a full-color atlas of anatomic drawings and surgical approaches, this trusted classic provides thorough coverage of kinematics and the mechanisms of trauma injury, the epidemiology of trauma, injury prevention, the basics of trauma systems, triage, and transport, and more. It then reviews generalized approaches to the trauma patient, from pre-hospital care and managing shock, to emergency department thoracotomy and the management of infections; delivers a clear, organ-by-organ survey of treatment protocols; and shows how to handle specific challenges in trauma―including alcohol and drug abuse, and combat-related wounds―in addition to post-traumatic complications such as multiple organ failure. 500 photos and illustrations Color atlas Numerous X-rays, CT scans, and algorithms High-yield section on specific approaches to the trauma patient A-to-Z overview of management of specific traumatic injuries Detailed discussion of the management of complications
The undisputed leader on the subject of geriatrics—updated to reflect the most recent advances in the field A Doody's Core Title for 2023! The leading text on the subject of geriatrics, this comprehensive guide combines gerontology principles with clinical geriatrics, offering unmatched coverage of this area of medicine. Anchored in evidence-based medicine and patient-centered practice, Hazzard's Geriatric Medicine and Gerontology presents the most up-to-date, medical information available. This updated eighth edition reflects the continued growth and increasing sophistication of geriatrics as a defined medical discipline. The book focuses on the implementation of key concepts and covers the foundation for geriatrics, as well as frequently encountered syndromes found in older adults. In addition, it provides valuable insights into the simultaneous management of multiple conditions, including psychological and social issues and their interactions, an intrinsic aspect of geriatric patient care. Features: A greater emphasize on the growing knowledge base for key topics in the field, including gerontology, geriatrics, geriatric conditions, and palliative medicine NEW chapters on: Social Determinants of Health, Health Disparities and Health Equity Age Friendly Care Geriatrics Around the World The Patient Perspective Substance Use and Disorders Applied Clinical Geroscience Managing the Care of Patients with Multiple Chronic Conditions UPDATED contributions from a respected and diverse team of geriatricians and subspecialists to reflect clinical breakthroughs and advances NEW: Extensive coverage of the COVID-19 pandemic and its impact on vulnerable older adults Updated Learning Objectives and Key Clinical Points Hundreds of full-color images
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