Modeling Microprocessor Performance focuses on the development of a design and evaluation tool, named RIPE (Rensselaer Interconnect Performance Estimator). This tool analyzes the impact on wireability, clock frequency, power dissipation, and the reliability of single chip CMOS microprocessors as a function of interconnect, device, circuit, design and architectural parameters. It can accurately predict the overall performance of existing microprocessor systems. For the three major microprocessor architectures, DEC, PowerPC and Intel, the results have shown agreement within 10% on key parameters. The models cover a broad range of issues that relate to the implementation and performance of single chip CMOS microprocessors. The book contains a detailed discussion of the various models and the underlying assumptions based on actual design practices. As such, RIPE and its models provide an insightful tool into single chip microprocessor design and its performance aspects. At the same time, it provides design and process engineers with the capability to model, evaluate, compare and optimize single chip microprocessor systems using advanced technology and design techniques at an early design stage without costly and time consuming implementation. RIPE and its models demonstrate the factors which must be considered when estimating tradeoffs in device and interconnect technology and architecture design on microprocessor performance.
Kenneth Macksey’s highly regarded biography of Generaloberst Heinz Guderian gives clear insight into the mind and motives of the father of modern tank warfare. Panzer General shows Guderian as a man of ideas equipped with the ability to turn inspiration into reality. A master of strategy and tactics, he was the officer most responsible for creating blitzkrieg in World War II. Guderian built the Panzerwaffe in the face of opposition from the German General Staff and personally led the lightning campaigns by tanks and aircraft that put a large part of Europe under domination by the Third Reich. Kenneth Macksey, a tank man himself for more than twenty years, reveals the man as a brilliant rebel in search of ideals and a general whose personality, genius, and achievements far transcended those of Rommel. As well as throwing light on the crucial campaigns in Poland, France, and Russia, this biography illuminates the struggles within the German hierarchy, both in the military and in the Nazi Party, for control of the Panzer forces. Based on information from the extensive family archives, Panzer General demonstrates why Guderian was so admired by some while denigrated by others.
A fascinating and detailed insight into tank warfare, from introduction during World War I to the war in Vietnam. After its introduction during the First World War, the tank revolutionised warfare, and proved to be a terrifying and efficient machine of war. Kenneth Macksey provides a study of the policy-makers and tank strategists, the technical and tactical development, as well as presenting the story of the tank on the battlefield the split-second decisions, the battle-weary crews and the endless mud in this fascinating and detailed account of tank warfare.
Nutrition is an essential part of life. It affects our health and can be applied in the prevention and treatment of disease. Substantial interventions in dietary intake and lifestyle changes have been demonstrated to cause significant decrease in disease risk in in the general population and also in patients suffering from various diseases. Traditional plant-based diets and medicines have received much attention as an alternative to modern science-based drugs, while recent technology development in bioinformatics, genomics, and proteomics has provided a better understanding of plant-based drugs, improved quality assurance and allowed the acceleration of clinical trials to bridge the gap with Western medicine. Moreover, research in nutrigenomics and epigenomics has further enhanced the knowledge of the association between nutrition and disease. The book deals with the concerns of the future well-being of our planet, the health of the global human population related to the worldwide obesity epidemic, the issues related to sustainable food production, and the need for a switch to a healthier, more plant-based diet.
Swaiman’s Pediatric Neurology, by Drs. Kenneth Swaiman, Stephen Ashwal, Donna Ferriero, and Nina Schor, is a trusted resource in clinical pediatric neurology with comprehensive, authoritative, and clearly-written guidance. Extensively updated to reflect advancements in the field, this fifth edition covers new imaging modalities such as pediatric neuroimaging, spinal fluid examination, neurophysiology, as well as the treatment and management of epilepsy, ADHD, infections of the nervous system, and more. The fully searchable text is now available online at www.expertconsult.com, along with downloadable images and procedural videos demonstrating intraventricular hemorrhage and white matter injury, making this an indispensable multimedia resource in pediatric neurology. Gain a clear visual understanding from the numerous illustrations, informative line drawings, and summary tables. Tap into the expertise of an authoritative and respected team of editors and contributors. Get comprehensive coverage of all aspects of pediatric neurology with a clinical focus useful for both the experienced clinician and the physician-in-training. Access the fully searchable text online at www.expertconsult.com, along with 16 additional online-only chapters, downloadable images, videos demonstrating intraventricular hemorrhage and white matter injury, and links to PubMed. Stay current on recent developments through extensive revisions: a new chapter on paraneoplastic syndromes in children; a new section on congenital brain malformations written by leading international authorities; and another one on cutting-edge pediatric neuroscience concepts relating to plasticity, neurodegeneration of the developing brain, and neuroinflammation. Apply the latest information on diagnostic modalities, including pediatric neuroimaging, spinal fluid examination, and neurophysiology
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology
The latest edition of Williams Textbook of Endocrinology edited by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, helps you diagnose and treat your patients effectively with up-to-the minute, practical know-how on all endocrine system disorders. Comprehensive yet accessible, this extensively revised 12th Edition updates you on diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much more so you can provide your patients with the most successful treatments. Find scientific insight and clinical data interwoven in every chapter, reflecting advances in both areas of this constantly changing discipline, and presented in a truly accessible format. You’ll also access valuable contributions from a dynamic list of expert authors and nearly 2.000 full-color images to help you with every diagnosis. This title has everything you need to manage any and all the clinical endocrinopathies you may encounter. Rely on the one reference that integrates rapidly evolving basic and clinical science in a cohesive, user-friendly format, definitively addresses every topic in the field, and has remained a standard for more than half a century. Update your know-how and skills to diagnose and treat your patients most effectively with exhaustively revised content on diabetes, metabolic disease, thyroid cancer, fertility problems, testicular problems, weight issues, and much more. Apply reliable guidance on endocrine conditions of growing interest like hypothyroidism and testicular disorders, with dedicated new chapters that expound on the latest research findings. Overcome any clinical challenge with comprehensive and easy-to-use coverage of everything from hormone activity, diagnostic techniques, imaging modalities, and molecular genetics, to total care of the patient. Apply the latest practices with guidance from expert authors who contribute fresh perspectives on every topic.
Occasionally, and if we are very fortunate, we meet someone who inspires us. Arnold Platt was such a person—he influenced and inspired many people whose lives he touched. His accomplishments suggest his genius, but as he chose the path of influence rather than power, his contributions were seldom credited publicly. How he came to have that influence and how he used it is a good story. But his story is also an illustration of agriculture’s role in shaping Canada’s political, economic, and social life in the twentieth century.
Get evidence-based guidelines to keeping athletic horses healthy and physically fit! Equine Sports Medicine and Surgery, 3rd Edition provides a comprehensive guide to exercise physiology and training within a clinical context, along with a detailed review of all diseases affecting horses participating in racing and competition. Not only does this text discuss the physiological responses of each body system to exercise, but it covers nutritional support, the prevention of exercise-induced disorders and lameness, and modification of training regimens. New to this edition are topics such as drug effects on performance and the use of cloud-based technologies for monitoring performance, as well as new content on exercise physiology, welfare, conditioning, farriery, behavior, and vision. Written by an expert team of international authors, each print purchase of this this authoritative, all-in-one resource comes with an ebook! - NEW! Chapters in this edition include: - History of Equine Exercise Physiology - Welfare of Equine Athletes in Sport and the Social License to Operate - The Connected Horse (focusing on innovative, cloud-based technologies used to monitor athletic horses) - Conditioning of the Equine Athlete - Principles of Sport Horse Farriery - Epidemiology and Control of Infectious Respiratory Disease in Populations of Athletic Horses - Behavior and Behavioral Abnormalities in Athletic Horses - Vision and Disorders of Vision in Performance Horses - Detection of Drug Use in Athletic Horses - Drug Effects on Performance of the Equine Athlete - Comprehensive coverage is based on sound research and evidence-based practice and provides an understanding of the physiologic processes underlying the responses of horses to exercise and physical conditioning — from musculoskeletal and respiratory disorders to nutrition and physical rehabilitation. - International perspective on equine athletics includes guidelines pertinent to different geographic areas and racing jurisdictions. - More than 1,000 images include medical illustrations and clinical photos depicting equine anatomy, testing, and treatment scenarios, as well as radiographic, ultrasonographic, CAT, and MRI imaging to support understanding and diagnosis. - Coverage of abnormalities of the upper airway is now divided into two chapters: Disease of the Nasopharynx and Diseases of the Larynx and Trachea. - Coverage of diseases of the heart is divided into two chapters: Arrhythmias and Abnormalities of the Cardiac Conduction System and Structural Heart Disease, Cardiomyopathy, and Diseases of Large Vessels. - eBook version, included with print purchase, gives you the power to access all the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everything that has made Williams Hematology the go-to resource for decades and has been updated with new chapters and critical new research into the molecular mechanisms responsible for hematological disorders and the impact on diagnosis and treatment. And the new format enables you to access each chapter via content modules covering key topics, with summaries, infographics, and cases―all linked to review questions for self-assessment. The full-color presentation integrates images of blood and tissue findings where they are cited in the text. NEW TO THIS EDITION: Updated and revised content reflecting the latest research and developments Convenient format that streamlines the learning process and improves retention Additional chapters added on: Immune Checkpoint Inhibitors Immune Cell Therapy: Chimeric Antigen Receptor T Cell Therapy Immune Cell Therapy Dendritic Cell and Natural Killer Cell Therapy The processes of cell death and survival Application of Big Data and Deep Learning in Hematology Williams Hematology Cases with multiple-choice questions including detailed explanations—perfect preparation for the boards Continuously updated online content with comprehensive drug therapy database and other resources
Occasionally, and if we are very fortunate, we meet someone who inspires us. Arnold Platt was such a person—he influenced and inspired many people whose lives he touched. His accomplishments suggest his genius, but as he chose the path of influence rather than power, his contributions were seldom credited publicly. How he came to have that influence and how he used it is a good story. But his story is also an illustration of agriculture’s role in shaping Canada’s political, economic, and social life in the twentieth century.
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