Presenting the landmark Pioneers life stories project, this one-of-a-kind book documents how modern social research in the UK was shaped. It combines a fascinating history of the generations who built outstanding and influential social research with a valuable resource for future research and teaching on methods.
Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.
Onetime seemingly unstoppable boxing champion, victim of a false conviction for a triple homicide, and spokesperson for the wrongfully incarcerated, Rubin “Hurricane” Carter is a controversial twentieth century icon. In this moving narrative, Dr. Carter tells of the metaphoric and physical prisons he has survived: his poverty-stricken childhood, his troubled adolescence and early adulthood, his 19-year imprisonment with 10 years in solitary confinement, and the knowledge that his life was forever altered by injustice. A spiritual as well as factual autobiography, his is not a comfortable story or a comfortable philosophy, but he offers hope for those who have none, and his words are a call to action for those who abhor injustice. Eye of the Hurricane may well change the way we view crime and punishment in the twenty-first century.
Covers the fundamentals and techniques of multiple biological sequence alignment and analysis, and shows readers how to choose the appropriate sequence analysis tools for their tasks This book describes the traditional and modern approaches in biological sequence alignment and homology search. This book contains 11 chapters, with Chapter 1 providing basic information on biological sequences. Next, Chapter 2 contains fundamentals in pair-wise sequence alignment, while Chapters 3 and 4 examine popular existing quantitative models and practical clustering techniques that have been used in multiple sequence alignment. Chapter 5 describes, characterizes and relates many multiple sequence alignment models. Chapter 6 describes how traditionally phylogenetic trees have been constructed, and available sequence knowledge bases can be used to improve the accuracy of reconstructing phylogeny trees. Chapter 7 covers the latest methods developed to improve the run-time efficiency of multiple sequence alignment. Next, Chapter 8 covers several popular existing multiple sequence alignment server and services, and Chapter 9 examines several multiple sequence alignment techniques that have been developed to handle short sequences (reads) produced by the Next Generation Sequencing technique (NSG). Chapter 10 describes a Bioinformatics application using multiple sequence alignment of short reads or whole genomes as input. Lastly, Chapter 11 provides a review of RNA and protein secondary structure prediction using the evolution information inferred from multiple sequence alignments. • Covers the full spectrum of the field, from alignment algorithms to scoring methods, practical techniques, and alignment tools and their evaluations • Describes theories and developments of scoring functions and scoring matrices •Examines phylogeny estimation and large-scale homology search Multiple Biological Sequence Alignment: Scoring Functions, Algorithms and Applications is a reference for researchers, engineers, graduate and post-graduate students in bioinformatics, and system biology and molecular biologists. Ken Nguyen, PhD, is an associate professor at Clayton State University, GA, USA. He received his PhD, MSc and BSc degrees in computer science all from Georgia State University. His research interests are in databases, parallel and distribute computing and bioinformatics. He was a Molecular Basis of Disease fellow at Georgia State and is the recipient of the highest graduate honor at Georgia State, the William M. Suttles Graduate Fellowship. Xuan Guo, PhD, is a postdoctoral associate at Oak Ridge National Lab, USA. He received his PhD degree in computer science from Georgia State University in 2015. His research interests are in bioinformatics, machine leaning, and cloud computing. He is an editorial assistant of International Journal of Bioinformatics Research and Applications. Yi Pan, PhD, is a Regents' Professor of Computer Science and an Interim Associate Dean and Chair of Biology at Georgia State University. He received his BE and ME in computer engineering from Tsinghua University in China and his PhD in computer science from the University of Pittsburgh. Dr. Pan's research interests include parallel and distributed computing, optical networks, wireless networks and bioinformatics. He has published more than 180 journal papers with about 60 papers published in various IEEE/ACM journals. He is co-editor along with Albert Y. Zomaya of the Wiley Series in Bioinformatics.
Private property is everywhere. Almost anywhere you walk in the United States, you will spot “No Trespassing” and “Private Property” signs on trees and fence posts. In America, there are more than a billion acres of grassland pasture, cropland, and forest, and miles and miles of coastlines that are mostly closed off to the public. Meanwhile, America’s public lands are threatened by extremist groups and right-wing think tanks who call for our public lands to be sold to the highest bidder and closed off to everyone else. If these groups get their way, public property may become private, precious green spaces may be developed, and the common good may be sacrificed for the benefit of the wealthy few. Ken Ilgunas, lifelong traveler, hitchhiker, and roamer, takes readers back to the nineteenth century, when Americans were allowed to journey undisturbed across the country. Today, though, America finds itself as an outlier in the Western world as a number of European countries have created sophisticated legal systems that protect landowners and give citizens generous roaming rights to their countries' green spaces. Inspired by the United States' history of roaming, and taking guidance from present-day Europe, Ilgunas calls into question our entrenched understanding of private property and provocatively proposes something unheard of: opening up American private property for public recreation. He imagines a future in which folks everywhere will have the right to walk safely, explore freely, and roam boldly—from California to the New York island, from the Redwood Forest to the Gulf Stream waters.
This volume comprises The Cassini Division and The Sky Road, the last two books of The Fall Revolution, Ken MacLeod's groundbreaking, multiple award-winning science fiction epic. The Cassini Division: In the 24th century, post humans, god-like descendents of humans who transformed themselves with high technology, have warped the very fabric of the solar system for unknowable reasons. Ellen May Ngewthu has a plan to rid humanity of these beings, but she must first travel the entirety of the Solar Union, convincing others that post-humans are the threat she knows they are... The Sky Road: Her rockets redundant, her people rebellious, and her borders defenseless against the Sino-Soviet Union, Myra Godwin appeals to the crumbling West for help as she faces the end of the space age. And, centuries in the future, as humanity again reaches into space, a young scholar could make the difference between success and failure. For his mysterious new lover has seduced him into the idea of extrapolating the ship's future from the dark archives of the past. The Sky Road won the British Science Fiction Association Award. The Fall Revolution Series: 1. The Star Fraction 2. The Stone Canal 3. The Cassini Division 4. The Sky Road At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.
Real-life Strategies, Insights, and Issues for Broadcast Journalists, Aspiring Journalists, Production Executives, and Broadcasters in the New Age of Broadcasting, Cable, and the Internet
Real-life Strategies, Insights, and Issues for Broadcast Journalists, Aspiring Journalists, Production Executives, and Broadcasters in the New Age of Broadcasting, Cable, and the Internet
An insider's look at the world of Broadcasting from the master of Career Choreography(TM). Are news and programming values and strategies changing? You bet they are! In The New Broadcasting Realities, Ken Lindner offers solutions to the complex issues and problems broadcasting professionals face in today's media landscape. Whether you're a media professional or an aspiring broadcast journalist, Lindner, who has guided the careers of hundreds of the nation's leading television newscasters and program hosts including Matt Lauer, Lester Holt, Elizabeth Vargas, Dr. Sanjay Gupta, Mario Lopez, Robin Meade, Megyn Kelly, Nancy O'Dell, and Samantha Harris, provides insider tips on Choreographing the steps of your broadcasting career. With case studies and an experienced, critical perspective, Lindner offers detailed advice on making career-enhancing decisions, including how to: - Multi-platform your career to enhance your visibility, brand, and marketability, as well as exponentially increase your income; - Strategically Choreograph your broadcasting career so that you are able to achieve your most cherished goals and dreams; - Negotiate the clauses in your employment contract(s) so that you are able to achieve your short- and long-term goals; and - Create effective solutions for hot-button issues and challenges that broadcasting professionals will inevitably face in The New Age of Broadcasting. The worlds of news and hosting are ever-changing, but Lindner's highly insightful examination of the issues facing broadcast journalists and broadcasters today will help you rise above the pack and maximize your potential.
Designing Experiments and Analyzing Data: A Model Comparison Perspective (3rd edition) offers an integrative conceptual framework for understanding experimental design and data analysis. Maxwell, Delaney, and Kelley first apply fundamental principles to simple experimental designs followed by an application of the same principles to more complicated designs. Their integrative conceptual framework better prepares readers to understand the logic behind a general strategy of data analysis that is appropriate for a wide variety of designs, which allows for the introduction of more complex topics that are generally omitted from other books. Numerous pedagogical features further facilitate understanding: examples of published research demonstrate the applicability of each chapter’s content; flowcharts assist in choosing the most appropriate procedure; end-of-chapter lists of important formulas highlight key ideas and assist readers in locating the initial presentation of equations; useful programming code and tips are provided throughout the book and in associated resources available online, and extensive sets of exercises help develop a deeper understanding of the subject. Detailed solutions for some of the exercises and realistic data sets are included on the website (DesigningExperiments.com). The pedagogical approach used throughout the book enables readers to gain an overview of experimental design, from conceptualization of the research question to analysis of the data. The book and its companion website with web apps, tutorials, and detailed code are ideal for students and researchers seeking the optimal way to design their studies and analyze the resulting data.
World War I continued with fury in the spring of 1918 as American Yanks endeavored to play the key role in stemming the German tide. Montana's Marines suffered the bloodiest day in their history as they became "Devil Dogs," charging through hell on earth at Belleau Wood. Locals in the Wild West Division stormed "over the top" into the Argonne Forest, while nurses, "hello girls," Navy Yeomanettes and YMCA workers blazed new gender roles. And young Seaman Mike Mansfield, future legendary senator, served on convoy duty against lurking German U-boats. Award-winning historian Ken Robison illuminates the story of young and vibrant Montanans of all ethnicities as they fought for elusive democracy, at home and abroad, in this world war to end all wars."--
In this authoritative Advanced Introduction, Ken Conca expertly examines the fundamentals of water politics, covering poverty, health and livelihoods alongside key areas such as water law, the environment, international politics and the growing role of climate change in water governance
Just when you thought it was safe to go into a bookshop, here is yet another book from that man at the Herald Diary. It is the usual scintillating mixture of anecdote, pith (no, there is no lithp involved) and fable. There will also be some funny photies. This is the fifth book in the Tom Shields trilogy. Yes, his counting is as awful as his writing. This time, however, Shields does not bare the blame alone. This tome is culled from the Diary columns that Shields and Ken Smith wrote together five days a week at The Herald. This was before Pepys the Elder left to embark on a glittering career as a freelance writer, leaving the column in the capable hands of the talented-ish, young-ish, handsome Mr Smith. Tom Shields' writing is featured in four other Mainstream books- Tom Shields' Diary, Tom Shields Too, Tom Shields Free at Last and Tom Shields Goes Forth.
Lavishly illustrated publication by a leading sculpture critic surveying the sculptures, practice, and significance of Andrew Rogers’ bronze, and stone geoglyphs (land sculpture) with additional contribution from internationally recognised writers, and critics, and many gifted photographers.
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