Next Generation Sequencing in Forensic Science: A Primer addresses next generation sequencing (NGS) specific to its application to forensic science. The first part of the book offers a history of human identity approaches, including VNTR, RFLP, STR, and SNP DNA typing. It discusses the history of sequencing for human DNA typing, including Sanger sequencing, SNaPshot, pyrosequencing, and principles of next generation sequencing. The chapters present an overview of the forensically focused AmpliSeq, ForenSeq, Precision ID, PowerSeq, and QIAseq panels for human DNA typing using autosomal, Y and X chromosome STRs and SNPs using the MiSeq FGx and Ion Torrent System. The authors outline the steps included in DNA extraction and DNA quantitation that are performed prior to preparing libraries with the NGS kits. The second half of the book details the implementation of ForenSeq and Precision ID to amplify and tag targets to create the library, enrich targets to attach indexes and adaptors, perform library purification and normalization, pool the libraries, and load samples to the cartridge to perform the sequencing on the instrument. Coverage addresses the operation of the MiSeq FGx and Ion Chef, including creating a sample list, executing wash steps, performing NGS, understanding the run feedback files from the instrument, and troubleshooting. ForenSeq and Precision ID panel data analysis are explained, including how to analyze and interpret NGS data and output graphs and charts. The book concludes with mitochondrial DNA (mtDNA) sequencing and SNPs analysis, including the issue of heteroplasmy. The final chapters review forensic applications of microbial DNA, NGS in body fluid analysis, and challenges and considerations for future applications. FEATURES Focuses on human identification using traditional and NGS DNA typing methods targeting short tandem repeats (STRs) Applies the technology and its application to law enforcement investigations and identity and ancestry single nucleotide polymorphisms (SNPs) for investigational leads, mass disaster, and ancestry cases Presents the underlying principles of NGS in a clear, easy-to-understand format for practitioners and students studying DNA in forensic programs This is the first book to prepare practitioners to utilize and implement this new technology in their lab for casework, highlighting early applications of how NGS results have been used in court. The book can be utilized for upper-level undergraduate and graduate students taking courses focused on NGS concepts. Readers are expected to have a basic understanding of molecular and cellular biology and DNA typing.
Collins-Bride & Saxe's Clinical Guidelines for Advanced Practice Nursing, Fourth Edition is an accessible and practical reference designed to support nurses and students in daily clinical decision making. Written by an interdisciplinary team of APRNs, it emphasizes collaboration for optimal patient-centered care and follows a lifespan approach with content divided into four clinical areas-Pediatrics, Sexual & Reproductive Health, Obstetrics, and Adult-Gerontology. To support varying advanced practice roles, the authors utilize the S-O-A-P (Subjective-Objective-Assessment-Plan) format for an organized and accessible teaching and learning experience.
First published in 1983. Leisure has too often been approached as a set of activities that people do when everything important has been completed. This text provides a different analysis demonstrating the centrality of leisure to human development and to important relationships. In Leisure Identities and Interactions the author analyses leisure in the context of role changes through the life course, but also as a social context in which we work out the identities that express who we really want to be. His focus is on the kinds of leisure that are both most common and most significant face-to-face encounters, family interaction, and episodes found in the midst of our roles and routines. Varieties of leisure styles are found to be developed out of available opportunities and in relation to cultural values, but also are chosen to express and negotiate our self-definitions. Leisure is both social and existential and can best be understood in the dialectic of role expectations and decision. Kelly utilizes symbolic interaction, interpretive, and dramaturgical metaphors to develop a different sociology of leisure one that brings together the concepts of role and identity. Expressive identities and intimate communities are as essential to leisure as they are to life.
The pharmacy of today is vastly different from the neighborhood pharmacy of fifty years ago. No longer do pharmacists fill out a prescription as written without question. Pharmacists in some communities work with patients, the patient's doctors, and insurance companies to manage the patient's disease states. Increasingly, they are the point of cont
This book explores the science inherent in good early years practice and provides a rich range of ideas to inspire you to ‘have a go’ in your setting. It provides a balance between theory which underpins good practice and plenty of ideas of how you might put the theory into practice. With a focus on how children learn about the world they live in and activities intended to develop scientific understanding the book offers an holistic approach, with key topics including: How children construct scientific meaning Tuning into children's initial scientific understanding How play supports the development of children's science ideas Providing a rich environment for learning early years science Developing children's scientific experiences This handy guide is ideal to support you if you are studying on an early years course, or if you are an established early years professional who wishes to enrich early scientific learning in your setting. Lois Kelly and Di Stead are Education Consultants specializing in primary science. This clearly written and engaging book examines Science in the Early Years through a variety of activities, including role-play, toys and technology. The vital importance of sensory experiences and language is emphasized throughout. The wide experience and knowledge of the authors guarantees a highly enjoyable read. The links to all curricula in the UK are extremely beneficial and I particularly liked the way that photographs and Key Points text boxes have been used throughout the book. The breadth and depth of writing about science makes this a highly desirable book for any practitioner working or studying in the Early Years. Kathy Brodie, Independent Early Years Consultant As an Early Years consultant who is passionate about children's thinking, exploring, questioning, investigating and most of all engaging…I really enjoyed this book. I especially liked it because it provokes practitioners to think about 'science' as the discovery and exploration of the world around us and not just as a National Curriculum subject. The mix of authors, their writing styles and the content of each chapter makes it a really easy and engaging read. Definitely one to add to your reading list if you work with children in the Early Years. Alistair Bryce-Clegg, Early Years Consultant As the title suggests, this book from the first page onwards inspires the reader to learn more about how to develop, enhance and incorporate effective practice in science in the early years. In addition to developing an understanding of how to approach the teaching of science, it gives a clearly articulated and accessible theoretical insight into how young children learn. To compliment this there are points of reflection, case studies, practical tasks and examples from the field. This is a valuable book for both students and practitioners alike as it goes beyond just giving suggestions for what to do; it explains the why and the how as well. Joanne McNulty, Manchester Metropolitan University This is a warm, accessible book, strongly grounded in research. It interweaves real life examples of science in the early years with underlying pedagogic principles and inspires new possibilities. The enthusiasm of the authors is contagious! Kendra McMahon, Bath Spa University
In this book, Duncan Kelly excavates, from the history of modern political thought, a largely forgotten claim about liberty as a form of propriety. By rethinking the intellectual and historical foundations of modern accounts of freedom, he brings into focus how this major vision of liberty developed between the seventeenth and the nineteenth centuries. In his framework, celebrated political writers, including John Locke, Montesquieu, Adam Smith, John Stuart Mill, and Thomas Hill Green pursue the claim that freedom is best understood as a form of responsible agency or propriety, and they do so by reconciling key moral and philosophical claims with classical and contemporary political theory. Their approach broadly assumes that only those persons who appropriately regulate their conduct can be thought of as free and responsible. At the same time, however, they recognize that such internal forms of self-propriety must be judged within the wider context of social and political life. Kelly shows how the intellectual and practical demands of such a synthesis require these great writers to consider freedom as part of a broader set of arguments about the nature of personhood, the potentially irrational impact of the passions, and the obstinate problems of individual and political judgement. By exploring these relationships, The Propriety of Liberty not only revises the intellectual history of modern political thought, but also sheds light on contemporary debates about freedom and agency.
A landmark in the study of early modern Europe, this two-volume collection makes available for the first time a selection of the most important texts from court and civic festival books. Festival entertainments were presented to mark such occasions as royal and ducal entries to capital cities, dynastic marriages, the birth and christening of heirs, religious feasts and royal and ducal funerals. Europa Triumphans represents the chronological and trans-European range of the court and civic festival. These festivals are considered not simply as texts, but as events, and are introduced by groups of scholars, each with a specialist knowledge of the political, social and cultural significance of the festival and of the iconography, spectacle, music, dance, voice and gesture in which they were expressed. To demonstrate the geographic spread and political significance of festivals, and to illustrate the range of aesthetic languages they deploy, the festivals included in these two volumes are grouped in the following sections: Henri III; Genoa; Poland-Lithuania; The Netherlands; The Protestant Union; La Rochelle; Scandinavia; and The New World. These texts provide many valuable insights into the variety of political systems and historical circumstances that formed them. Beautifully produced with 148 black-and-white and 23 colour illustrations, Europa Triumphans represents an invaluable reference source for the study of early modern Europe. It presents texts both in transcription and translated into English, and is supplemented with introductory essays and commentaries. Europa Triumphans is co-published by Ashgate and the Modern Humanities Research Association, in conjunction with the AHRB Centre for the Study of the Renaissance at the University of Warwick, UK.
A practical reference guide for orthopedic surgeons, fellows, and residents interested in shoulder surgery, Premier Approaches to Arthroscopic Rotator Cuff Repair explains the latest techniques in arthroscopic surgery for rotator cuff repair and incorporates evidence-based recommendations to help readers select the best surgical techniques for their patients. Rotator cuff disease is common and debilitating, but postoperative retear rates remain high. While technological advances have led to an increase in popularity and prominence of arthroscopic rotator cuff repair, some procedures require a steep learning curve. This work will prove to be a great resource for surgeons seeking proficiency in contemporary arthroscopic techniques pertaining to the rotator cuff. Edited by Dr. John D. Kelly IV and with contributions from leading orthopedic surgeons, Premier Approaches to Arthroscopic Rotator Cuff Repair provides readers with the most up-to-date, evidence-based knowledge regarding arthroscopic rotator cuff repair including elaboration of: Double-row repair technique Subscapularis tear approaches Value of oblique reduction Partial repair strategies Indications for graft augmentation Role of biologic augmentation Superior capsular reconstruction Role of fatty infiltration Suprascapular nerve release The text concludes with a chapter on rehabilitation after rotator cuff repair that underscores the importance of a progressive program, individualized to each patient and coordinated among the surgeon, therapist, and patient. Premier Approaches to Arthroscopic Rotator Cuff Repairis an invaluable book compiled by Master Surgeons that provides a foundation for implementation of the most recent and effective care of those afflicted with rotator cuff tears.
Drug interactions have become a significant iatrogenic complication, with as many as 5% of hospitalizations and 7,000 deaths annually attributable to drug-drug interactions in the United States. There are several reasons these numbers have increased. First, many new medications have been brought to market in recent years. Second, advances in medical care have resulted in increased longevity and more elderly patients than ever before -- patients who are more likely to be following polypharmacy regimens. Population patterns in the U.S. have amplified this trend, with aging baby boomers swelling the patient pool and demanding treatment with medications advertised on television and in print. Fortunately, drug interactions can be prevented with access to current, comprehensive, reliable information, and the Clinical Manual of Drug Interaction Principles for Medical Practice provides just that in a user-friendly format psychiatry clinicians (including residents and nurses) and forensics experts will find indispensable. With this new edition, the book has evolved from "Concise Guide" to "Clinical Manual" and offers the expanded coverage and features healthcare providers need to keep up with this critical field. The book is well organized, with major sections on metabolism; cytochrome P450 enzymes; drug interactions by medical specialty; and practical matters, such as the medicolegal implications of drug-drug interactions and how to retrieve and review the literature. In the section on P450 enzymes, each chapter addresses what the individual enzyme does and where, its polymorphisms, and drugs that inhibit or induce activity. Each chapter also includes extensive references and study cases to help the reader understand and contextualize the information. A number of additional features enhance the book's scope and utility: The book boasts the very latest information in the area of drug metabolism, transport, and interaction. The chapter on P-glycoprotein (a drug transporter) was expanded from the last edition to include a broader array of transport mechanisms. The highest ethical standard was adhered to in the development of this volume, which was not supported in any way by pharmaceutical makers or distributors. All eight contributors to this excellent resource are experts in the fields they have addressed, and clinicians can trust that the information contained in the Manual reflects the very latest research. This exceptionally practical manual is essential to maintaining the highest standard of care.
Covering both the theoretical and practical aspects of critical care,Irwin & Rippe’s Intensive Care Medicine, Ninth Edition, provides state-of-the-art, evidence-based knowledge for specialty physicians and non-physicians practicing in the adult intensive care environment. Drs. Craig M. Lilly, Walter A. Boyle, and Richard S. Irwin, along with a team of expert contributing authors and education expert, William F. Kelly, offer authoritative, comprehensive guidance from an interprofessional, collaborative, educational, and scholarly perspective, encompassing all adult critical care specialties.
TOPICS IN THE BOOK Influence of Welding Parameters on Strength of Metal Inert Gas Welded Mild Steel Joints Real-Time Data Streaming and AI Enhancements: E-Commerce Live Streaming Shopping Comparing Conformal and Quantile Regression for Uncertainty Quantification: An Empirical Investigation The Impact of Edge Computing on Real-Time Data Processing Wearable Technology for Health Monitoring and Diagnostics
This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Kelly Hunt, is devoted to Changing Paradigms in Breast Cancer Diagnosis and Treatment. Dr. Hunt has assembled expert authors to review the following topics: Tomosynthesis in breast cancer imaging: how does it fit into preoperative evaluation and surveillance?; Lobular breast cancer: different disease, different algorithms?; Hypofractionated radiation therapy in breast conserving therapy; Oncoplastic breast reconstruction: should all patients be considered?; Neoadjuvant endocrine therapy: who benefits most?; Breast cancer disparities: how can we leverage genomics to improve outcomes?; Anatomy and breast cancer staging: is it still relevant?; When does atypical ductal hyperplasia require surgical intervention?; Surgical intervention for lymphedema; Are there alternative strategies in the local management of DCIS?; Genetic testing and genetic counseling: what is standard of care?; Molecular subtypes and local-regional control of breast cancer; Intraoperative margin assessment in breast cancer management; Triple negative breast cancer: who should receive neoadjuvant chemotherapy?; and more!
The Importance of the Dissertation in Practice (DiP): A Resource Guide for EdD Students, Their Committee Members and Advisors, and Departmental and University Leaders Involved with EdD Programs is the first book-length study that looks at the elements of high-quality Dissertations in Practice (DiPs). It serves as a resource for EdD students, their committee members, their advisors, and departmental or university leaders involved with EdD programs. The book can be used to improve support from key stakeholders within EdD programs for the implementation of the DiP in the development of practitioner-scholars. The first section of the book discusses the difference between the DiP and traditional dissertations, the history of the DiP, and how the practitioner-scholar is developed through the DiP process. Next, the book describes the elements that are reflective of a high-quality DiP. Finally, it addresses a few of the unique formats that are sometimes used with the DiP, some of the practical issues with implementing the DiP, and issues of the future including the use of artificial intelligence. The ultimate goal of The Importance of the Dissertation in Practice is to serve as a practical guide for all those involved with the DiP, reflecting the editors’ and authors’ experiences working with students within a variety of higher education institutions. Perfect for courses such as: Introduction to Research Methods (doctoral level); Improvement Science; Applied Research Methods; Advanced Research Methods; Introduction to the Dissertation; Educational Evaluation; Theory of Change in Education; Educational Policy
There are instructions for those with experience in building on how to build a tumbling barrel composter which is covered in about 14 pages including pictures and diagrams. Building a composting system doesn't have to cost much and is much more economical then purchasing one. The author covers how to use compost and about vermicomposting, which is composting using worms. In the back she includes the web address for each state's Cooperative Extension System (these sites include agricultural information specific to your state) and information about companies who sell composters. Ms. Smith definitely has done her research and this book is a good one to keep on hand when deciding to compost. With it, the reader can make a determination of what type of composting would work best for them and cost effective ways to start and maintain a composting system.
Pharmacology, Biology, and Clinical Applications of AndrogensCurrent Status and Future Prospects Edited by Shalender Bhasin, Henry L. Gabelnick, Jeffrey M. Spieler,Ronald S. Swerdloff, Christina Wang, and Chuck Kelly As agents that affect the male primary and accessory sex organs,androgens--particularly the hormones testosterone andandrosterone--play a critical role in the development,functionality, and overall health of the male reproductive system.However, since androgens also have far-ranging effects onmetabolism, neurological activity, and behavior, scientistsexploring the contraceptive or therapeutic potential of androgensneed reliable, up-to-date information on the complex biologicalactivities of these agents. Pharmacology, Biology, and Clinical Applications of Androgens:Current Status and Future Prospects presents contributions fromleading investigators around the world, offering a focused,state-of-the-art summary of the central issues and controversies inandrogen research. The book is arranged into sections coveringandrogen physiology, androgens and the prostate, and theneurobehavioral and metabolic effects of androgens--as well astheir role in disease therapy and male contraception, and thevarious delivery systems for each application. Every chapter in thetext provides an expert opinion on a cutting-edge topic in thefield while highlighting the key points of dissent and disagreementwithin the scientific community. This approach is intended tofoster a deeper understanding of the status of androgen researchand lay the groundwork for future investigations in eacharea. This book explores such current topics as: * Androgen regulation of Sertoli cell function * Testosterone and spermatogenesis * Androgen effects on benign prostatic hyperplasia (BPH) andprostate cancer * Androgen effects on cognitive processes, sexual function, andaggressive behavior * Contraceptive efficacy of hormonal suppression of spermatogenesis * The latest transdermal and implantation delivery systems forandrogens Offering multifaceted coverage of the field, Pharmacology, Biology,and Clinical Applications of Androgens is an indispensable aid toall basic scientists and clinical investigators interested in thebiological actions of either natural or synthetic androgens.
* THE INSTANT NEW YORK TIMES BESTSELLER * Scientific American’s #1 Book for 2023 * A New York Times Book Review Editors' Choice * A Times Best Science and Environment Book of 2023 * “Exceptional. . . Forceful, engaging and funny . . . This book will make you happy to live on this planet — a good thing, because you’re not leaving anytime soon.” —New York Times Book Review From the bestselling authors of Soonish, a brilliant and hilarious off-world investigation into space settlement Earth is not well. The promise of starting life anew somewhere far, far away—no climate change, no war, no Twitter—beckons, and settling the stars finally seems within our grasp. Or is it? Critically acclaimed, bestselling authors Kelly and Zach Weinersmith set out to write the essential guide to a glorious future of space settlements, but after years of research, they aren’t so sure it’s a good idea. Space technologies and space business are progressing fast, but we lack the knowledge needed to have space kids, build space farms, and create space nations in a way that doesn’t spark conflict back home. In a world hurtling toward human expansion into space, A City on Mars investigates whether the dream of new worlds won’t create nightmares, both for settlers and the people they leave behind. In the process, the Weinersmiths answer every question about space you’ve ever wondered about, and many you’ve never considered: Can you make babies in space? Should corporations govern space settlements? What about space war? Are we headed for a housing crisis on the Moon’s Peaks of Eternal Light—and what happens if you’re left in the Craters of Eternal Darkness? Why do astronauts love taco sauce? Speaking of meals, what’s the legal status of space cannibalism? With deep expertise, a winning sense of humor, and art from the beloved creator of Saturday Morning Breakfast Cereal, the Weinersmiths investigate perhaps the biggest questions humanity will ever ask itself—whether and how to become multiplanetary. Get in, we’re going to Mars.
Computer: A History of the Information Machine traces the history of the computer and shows how business and government were the first to explore its unlimited, information-processing potential. Old-fashioned entrepreneurship combined with scientific know-how inspired now famous computer engineers to create the technology that became IBM. Wartime needs drove the giant ENIAC, the first fully electronic computer. Later, the PC enabled modes of computing that liberated people from room-sized, mainframe computers. This third edition provides updated analysis on software and computer networking, including new material on the programming profession, social networking, and mobile computing. It expands its focus on the IT industry with fresh discussion on the rise of Google and Facebook as well as how powerful applications are changing the way we work, consume, learn, and socialize. Computer is an insightful look at the pace of technological advancement and the seamless way computers are integrated into the modern world. Through comprehensive history and accessible writing, Computer is perfect for courses on computer history, technology history, and information and society, as well as a range of courses in the fields of computer science, communications, sociology, and management.
An exploration of the character and evolution of disgust and the role this emotion plays in our social and moral lives. People can be disgusted by the concrete and by the abstract—by an object they find physically repellent or by an ideology or value system they find morally abhorrent. Different things will disgust different people, depending on individual sensibilities or cultural backgrounds. In Yuck!, Daniel Kelly investigates the character and evolution of disgust, with an emphasis on understanding the role this emotion has come to play in our social and moral lives. Disgust has recently been riding a swell of scholarly attention, especially from those in the cognitive sciences and those in the humanities in the midst of the "affective turn." Kelly proposes a cognitive model that can accommodate what we now know about disgust. He offers a new account of the evolution of disgust that builds on the model and argues that expressions of disgust are part of a sophisticated but largely automatic signaling system that humans use to transmit information about what to avoid in the local environment. He shows that many of the puzzling features of moral repugnance tinged with disgust are by-products of the imperfect fit between a cognitive system that evolved to protect against poisons and parasites and the social and moral issues on which it has been brought to bear. Kelly's account of this emotion provides a powerful argument against invoking disgust in the service of moral justification.
Around 2004, members of governmental and nongovernmental organizations, science institutes, and private companies throughout India began brainstorming and then experimenting with small-scale treatment systems that could produce usable water from wastewater. Through detailed case studies, Microbial Machines describes how residents, workers, and scientists interact with technology, science, and engineering during the processes of treatment and reuse. Using a human-machine-microbe framework, Kelly Alley explores the ways that people's sensory perceptions of water—including disgust—are dynamic and how people use machines and microbes to digest wastewater. A better understanding of how the human and nonhuman interact in these processes will enable people to generate more effective methods for treating and reusing wastewater. While decentralized wastewater treatment systems may not be a perfect solution, they alleviate resource stress in regions that are particularly hard hit by climate change. These case studies have broad relevance for solving similar problems in many other places around the world.
The emotional and social components of teaching medical students to be good doctors The pelvic exam is considered a fundamental procedure for medical students to learn; it is also often the one of the first times where medical students are required to touch a real human being in a professional manner. In Feeling Medicine, Kelly Underman gives us a look inside these gynecological teaching programs, showing how they embody the tension between scientific thought and human emotion in medical education. Drawing on interviews with medical students, faculty, and the people who use their own bodies to teach this exam, Underman offers the first in-depth examination of this essential, but seldom discussed, aspect of medical education. Through studying, teaching, and learning about the pelvic exam, she contrasts the technical and emotional dimensions of learning to be a physician. Ultimately, Feeling Medicine explores what it means to be a good doctor in the twenty-first century, particularly in an era of corporatized healthcare.
How do you create a learning environment that’s productive; one where students are engaged, learning and happy? And how do you ensure that inappropriate behaviours are kept to a minimum? The second edition of Positive Learning Environments: Creating and Maintaining Productive Classrooms introduces the key concepts teachers need to know to create and maintain their classroom as a positive learning environment. It begins by introducing four essential components that are the cornerstones of creating a positive, productive learning environment. These positive practices set readers on the pathway to success and help them establish classrooms that recognise and encourage appropriate behaviours while reducing the probability of inappropriate behaviours. It then examines in turn each of the four main groups of evidence-based approaches to managing student behaviour: behavioural, cognitive behavioural, psychoeducational and social justice approaches. For each it discusses the theories that inform them, their practical applications for fostering appropriate behaviours and also when and how to use them to proactively intervene, if necessary. By the end, readers are empowered to select appropriate theories, approaches and strategies and bring these together to develop their individualised classroom management plan: one that suits their own theoretical beliefs, professional philosophy and teaching style. Premium online teaching and learning tools are available on the MindTap platform. Learn more about the online tools cengage.com.au/mindtap
The complex phenomenon of colour has received detailed attention from the perspectives of physics, chemistry, physiology, psychology, linguistics and philosophy. However, the people who work most closely with colour artists have rarely been canvassed for their opinions on this mysterious subject.John Gage sets out to address this omission by focusing on the thoughts and practices of artists. Colour in Art is concerned with the history of colour, but is not itself a history; instead each chapter develops a theme from a different scientific discipline, as seen from the viewpoint of such diverse artists such as Wassily Kandinsky, Vincent van Gogh, Sonia Delaunay, Bridget Riley and Clifford Possum Tjapaltjarri. Drawing on examples through the ages, from ancient times to the present, the many topics covered include flags, synaesthesia, Theosophy, theatre design, film, chromotherapy and chromophobia.Featuring a new foreword by art writer Kelly Grovier outlining contemporary developments in the study of colour, and an updated bibliography, this new edition of this classic text offers a wide-ranging and engaging introduction to the place and power of colour in life and art.
The Dred Scott suit for freedom, argues Kelly M. Kennington, was merely the most famous example of a phenomenon that was more widespread in antebellum American jurisprudence than is generally recognized. The author draws on the case files of more than three hundred enslaved individuals who, like Dred Scott and his family, sued for freedom in the local legal arena of St. Louis. Her findings open new perspectives on the legal culture of slavery and the negotiated processes involved in freedom suits. As a gateway to the American West, a major port on both the Mississippi and Missouri Rivers, and a focal point in the rancorous national debate over slavery’s expansion, St. Louis was an ideal place for enslaved individuals to challenge the legal systems and, by extension, the social systems that held them in forced servitude. Kennington offers an in-depth look at how daily interactions, webs of relationships, and arguments presented in court shaped and reshaped legal debates and public attitudes over slavery and freedom in St. Louis. Kennington also surveys more than eight hundred state supreme court freedom suits from around the United States to situate the St. Louis example in a broader context. Although white enslavers dominated the antebellum legal system in St. Louis and throughout the slaveholding states, that fact did not mean that the system ignored the concerns of the subordinated groups who made up the bulk of the American population. By looking at a particular example of one group’s encounters with the law—and placing these suits into conversation with similar encounters that arose in appellate cases nationwide—Kennington sheds light on the ways in which the law responded to the demands of a variety of actors.
The best single resource available for evaluating and comparing more than 1200 commonly-used medications 4 STAR DOODY'S REVIEW! "Although the primary audience for this book is practicing pharmacists, clinical pharmacists, pharmacy residents, and pharmacy students, the wide range of audiences who may benefit from this book include physicians and medical residents who may find this a useful resource, especially with the downloadable option....This is a useful and easy to use reference. Information is systematically organized in an easy to retrieve way."--Doody's Review Service "...will be useful to all health care professionals in a clinical setting." - Review of an earlier edition from the Australian Journal of Hospital Pharmacy Now includes PDA download of the entire text! Uniquely designed to allow comparisons within drug categories, Handbook of Clinical Drug Data is the most comprehensive, well-referenced book available on the selection, use, and clinical aspects of virtually any drug. Compiled by expert clinicians, this quick-access guide delivers the data you need to prevent adverse drug reactions in your patients and help you select drugs for both general and special patient populations Features Full-text PDA download More than 3800 literature citations Comparison charts of drugs by class facilitates clinical decision making Tables to help you rapidly identify the cause of adverse drug effects in patients Guidance on the optimal choice of drugs in special populations, including pregnant and breastfeeding women, and geriatric patients Genetic and ethic considerations Extensively cross-referenced index includes Canadian and British drug names Valuable appendices that include Conversion Factors, Anthropometrics, Laboratory Indices, Pharmacokinetic Equations, and more
The goal of teaching online is fundamentally the same as teaching face-to-face: facilitating the learning of all students to the greatest extent possible. This book differs from other books on online teaching in that, in the process of offering guidance on course design and planning, developing outcomes and appropriate engaging activities, managing the workload and assessment, the authors pay explicit attention throughout to the distinct and diverse needs of students and offer effective strategies to accommodate them in a comprehensive and inclusive way by using the principles of Universal Design for Learning. By following those principles from the outset when planning a course, all students will benefit, and most particularly those whom the research shows have the greatest achievement gaps when taking online courses -- males, first generation and low income students, those from underrepresented minority groups, the academically underprepared, students with disabilities, and those with limited online access or lacking readiness for online learning. Beyond good planning and design, Kelly and Zakrajsek offer ideas for creating inclusive course environments and activities, such as using culturally appropriate content and making it accessible in multiple formats. They also share methods to foster faculty-learner interaction and increase personal connections with students, and among students, through group activities or learning communities, which are so critical to motivation and success. Faculty new to online teaching as well as more experienced readers will find a wealth of practical guidance on developing and honing both fully online and blended courses and, as importantly, a wealth of proven ideas to help the new generation of students with diverse needs to succeed.
Information technology professionals will gain invaluable information with this updated resource on how to connect concepts to key business areas. These areas include accounting, finance, marketing, management, human resources, and operations. The new edition provides concise and accessible coverage of core IT topics. Do It Yourself activities show them how to apply the information on the job. Technology professionals will then be able to discover how critical IT is to each functional area and every business.
The untold stories of bravery, triumph, and redemption in the depths of the darkest world war. Behind the great powers, global military conflict, and infamous battles are more than 100 incredible stories that bring to life the Second World War. During the six years of war were countless little-known moments of profound triumph and tragedy, bravery and cowardice, and good and evil. These amazing and unbelievable stories of brotherhood, redemption, escape, and civilian courage shed new light on the war that gripped the entire world. Experience the action through the eyes of people like: Lieutenant Jacob Beser, who was aboard both the Enola Gay and Bock's Car and felt the force of the shockwave that nearly destroyed the planes after dropping the H-bombs that obliterated Hiroshima and Nagasaki. Professor William Miller, who collapsed during a death march of POWs in Germany and was saved by the same man who had rescued him from what would have been a fatal car wreck in Pennsylvania five years earlier. The brave civilians who answered the British Admiralty's call to help rescue an army from Dunkirk during the height of a dangerous battle and sailed small fishing boats into relentless German fire, ultimately saving 335,000 men from This is the perfect book for any history buff looking for the untold stories of military and civilian daring during World War 2.
Faith in the power and righteousness of retribution has taken over the American criminal justice system. Approaching punishment and responsibility from a philosophical perspective, Erin Kelly challenges the moralism behind harsh treatment of criminal offenders and calls into question our society’s commitment to mass incarceration. The Limits of Blame takes issue with a criminal justice system that aligns legal criteria of guilt with moral criteria of blameworthiness. Many incarcerated people do not meet the criteria of blameworthiness, even when they are guilty of crimes. Kelly underscores the problems of exaggerating what criminal guilt indicates, particularly when it is tied to the illusion that we know how long and in what ways criminals should suffer. Our practice of assigning blame has gone beyond a pragmatic need for protection and a moral need to repudiate harmful acts publicly. It represents a desire for retribution that normalizes excessive punishment. Appreciating the limits of moral blame critically undermines a commonplace rationale for long and brutal punishment practices. Kelly proposes that we abandon our culture of blame and aim at reducing serious crime rather than imposing retribution. Were we to refocus our perspective to fit the relevant moral circumstances and legal criteria, we could endorse a humane, appropriately limited, and more productive approach to criminal justice.
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Nutrition** Provide optimal nutritional care with the latest guidelines to evidence-based practice! Krause and Mahan's Food & the Nutrition Care Process, 16th Edition provides an all-in-one resource for the dietetics information you need to care for patients throughout the entire life cycle. With insight from clinical specialists, the book guides you through the steps of assessment, diagnosis and intervention, monitoring, and evaluation. It also covers nutrition in each stage of life, weight management, medical nutrition therapies for conditions and disorders, and the use of nutrition therapies in childhood. From a team of nutrition experts led by Janice L. Raymond and Kelly Morrow, this classic text has been trusted by nurses, nutritionists, and dieticians for since 1952. - UNIQUE! Pathophysiology algorithms and flow charts present the cause, pathophysiology, and medical nutrition management for a variety of disorders and conditions to help you understand illness and provide optimal nutritional care. - Clinical case studies help you translate academic knowledge into practical patient care using a framework of the nutrition care process. - Sample Nutrition Diagnosis boxes present a problem, its etiology, and its signs and symptoms, then conclude with a nutrition diagnosis, providing scenarios you may encounter in practice. - Clinical Insight boxes expand on information in the text, highlight new areas of focus, and contain information on studies and clinical resources. - New Directions boxes suggest areas for further research by spotlighting emerging areas of interest in nutrition care. - Focus On boxes provide thought-provoking information on key nutrition concepts. - Summary boxes highlight CRISPR, the Indigenous food movement, hearing assessment, health disparities, and the Health At Every Size movement, and include a tribute to Dr. George Blackburn, a respected specialist in obesity and nutrition. - Key terms are listed at the beginning of each chapter and bolded within the text. - NEW Infectious Diseases chapter is written by a new author with specific expertise in infectious disease. - NEW Transgender Nutrition chapter is added, from two new authors. - NEW! COVID-19 updates are provided in multiple chapters, each relating to epidemiology and patient care. - NEW! Information on the FODMAP diet is included in the appendix, covering the sugars that may cause intestinal distress. - NEW! Emphasis on diversity, equity, and inclusion is included in all chapters. - NEW! Updated International Dysphagia Diet Standardisation Initiative (IDDSI) information is included in the appendix. - NEW! Updated pregnancy growth charts are added to this edition. - NEW! Updated Healthy People 2030 information is added throughout the book.
- NEW! Food-Nutrient Delivery: Planning the Diet with Cultural Competency chapter provides international nutrition guidelines and resources to assist you with multicultural meal planning. - NEW! Clinical: Nutritional Genomics chapter features an author from the NIH's Human Genome Project and introduces you to the latest research about CRISPR and epigenetics. - NEW! MNT for Neurologic Disorders chapter features two new authors, including a speech therapist, and displays IDDSI guidelines and an appendix for dysphagia diets to help you carefully and consistently address the nutritional needs of these patients. - NEW! Clinical: Water, Electrolytes, and Acid-Base Balance and Clinical: Biochemical, Physical, and Functional Assessment chapters are updated with the most relevant and evidence-based complementary and integrative approaches to expand your expertise in these clinical nutritional areas. - NEW! MNT for Adverse Reactions to Food: Food Allergies and Intolerance chapter features completely revised guidelines and a new pathophysiology algorithm to ensure you are confident in your knowledge of how to prevent emergencies and what to do when emergencies do happen. - NEW! Coverage of intermittent fasting, health at every size, and health disparities focuses on the latest nutrition trends to ensure you are well-versed in these topics. - NEW! The Mediterranean Diet, Choline, and Biotin appendices display at-a-glance information to help you find quickly supplemental information. - NEW! Directions boxes and Focus On boxes, as well as useful websites, resources, and key terms at the end of each chapter, help you find information quickly and easily.
A must read for every pharmacy student Market: Pharmacy students (35,000) Experts in the field discuss residency, fellowships, and additional degrees Related McGraw-Hill Title: Freeman: The Ultimate Guide To Choosing a Medical Specialty 978-0-07-145713-2 * 0-07-145713-5 * Paperback * $35.00MD
Four decades have passed since reports of a mysterious “gay cancer” first appeared in US newspapers. In the ensuing years, the pandemic that would come to be called AIDS changed the world in innumerable ways. It also gave rise to one of the late twentieth century’s largest health-based empowerment movements. Scholars across diverse traditions have documented the rise of the AIDS activist movement, chronicling the impassioned echoes of protestors who took to the streets to demand “drugs into bodies.” And yet not all activism creates echoes. Included among the ranks of 1980s and 1990s-era AIDS activists were individuals whose expressions of empowerment differed markedly from those demanding open access to mainstream pharmaceutical agents. Largely forgotten today, this activist tradition was comprised of individuals who embraced unorthodox approaches for conceptualizing and treating their condition. Rejecting biomedical expertise, they shared alternative clinical paradigms, created underground networks for distributing unorthodox nostrums, and endorsed etiological models that challenged the association between HIV and AIDS. The theatre of their protests was not the streets of New York City’s Greenwich Village but rather their bodies. And their language was not the riotous chants of public demonstration but the often-invisible embrace of contrarian systems for defining and treating their disease. The Sounds of Furious Living seeks to understand the AIDS activist tradition, identifying the historical currents out of which it arose. Embracing a patient-centered, social historical lens, it traces historic shifts in popular understanding of health and perceptions of biomedicine through the nineteenth and twentieth centuries to explain the lasting appeal of unorthodox health activism into the modern era. In asking how unorthodox health activism flourished during the twentieth century’s last major pandemic, Kelly also seeks to inform our understanding of resistance to biomedical authority in the setting of the twenty-first century’s first major pandemic: COVID-19. As a deeply researched portrait of distrust and disenchantment, The Sounds of Furious Living helps explain the persistence of movements that challenge biomedicine’s authority well into a century marked by biomedical innovation, while simultaneously posing important questions regarding the meaning and metrics of patient empowerment in clinical practice.
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