A gripping history that spans law, international affairs, and top-secret technology to unmask the tension between intellectual property rights and national security. At the beginning of the twentieth century, two British inventors, Arthur Pollen and Harold Isherwood, became fascinated by a major military question: how to aim the big guns of battleships. These warships—of enormous geopolitical import before the advent of intercontinental missiles or drones—had to shoot in poor light and choppy seas at distant moving targets, conditions that impeded accurate gunfire. Seeing the need to account for a plethora of variables, Pollen and Isherwood built an integrated system for gathering data, calculating predictions, and transmitting the results to the gunners. At the heart of their invention was the most advanced analog computer of the day, a technological breakthrough that anticipated the famous Norden bombsight of World War II, the inertial guidance systems of nuclear missiles, and the networked “smart” systems that dominate combat today. Recognizing the value of Pollen and Isherwood’s invention, the British Royal Navy and the United States Navy pirated it, one after the other. When the inventors sued, both the British and US governments invoked secrecy, citing national security concerns. Drawing on a wealth of archival evidence, Analog Superpowers analyzes these and related legal battles over naval technology, exploring how national defense tested the two countries’ commitment to individual rights and the free market. Katherine C. Epstein deftly sets out Pollen’s and Isherwood’s pioneering achievements, the patent questions raised, the geopolitical rivalry between Britain and the United States, and the legal precedents each country developed to control military tools built by private contractors. Epstein’s account reveals that long before the US national security state sought to restrict information about atomic energy, it was already embroiled in another contest between innovation and secrecy. The America portrayed in this sweeping and accessible history isn’t yet a global hegemon but a rising superpower ready to acquire foreign technology by fair means or foul—much as it accuses China of doing today.
This is the second volume of the bestselling annual, Serial Killers True Crime Anthology, a collection of some of the best true crime writing on serial killers over the year. Several of these authors who appeared in Volume 1 of the Anthology, return this year to Volume 2 with new stories. 2015 Serial Killers True Crime Anthology Volume 2: Peter Vronsky in the chilling story "Zebra! The Hunting Humans 'Ninja' Truck Driver Serial Killer" describes the carnage perpetrated in 2007 by Adam Leroy Lane, a long haul truck driving serial killer who after repeatedly watching in his truck cab a serial killer DVD movie he was obsessed with, forayed out in the night from Interstate highway truck-stops dressed in Ninja black to re-enact the movie scenes by killing and mutilating unsuspecting women in their homes until he was captured by a fifteen-year old girl and her parents when he attempted to kill her as she slept in her bedroom.RJ Parker in "Demons" introduces us to the little known story of Canada's serial killer Michael Wayne McGray who murdered men, women and children indiscriminately and whom even prison could not stop from continuing his killing. In the "Grim Sleeper" Parker describes the brutal crimes of Lonnie Franklin, Jr. who over a 23-year killing career, took a fourteen-year hiatus (thus his nickname) before resuming his murders of women in Los Angeles.Katherine Ramsland in "The Babysitter" brings us up to date on the still unsolved horrific1976 mutilation child murders in Detroit that inspired Bill Connington's one-man Broadway play and Joyce Carol Oates 1995 novella Zombie. In "Really! The Other Guy Did It." Ramsland explores the bizarre case of serial killer Douglas Perry who after killing several women underwent a transsexual change into a woman, Donna Perry, who when apprehended, claimed the murders were perpetrated by his former male self who no longer existed. Ramsland asks, "Is guilt in the body or the soul?" Michael Newton in "Bad Medicine" and "Angel of Death" describes two serial killers where we least expect them: health care workers. Physician Dr. Harold Shipman who murdered 250 victims in Britain and might be history's most prolific serial killer, and the smiling mild mannered Ohio medical orderly 'Angel of Death' Donald Harvey, who confessed to murdering 87 helpless patients, stating, "So I played God."Sylvia Perrini, Britain's true crime chronicler of female serial killers in "The House of Horrors" revisits the notorious case of Rosemary West who teamed up with her husband Fred in the rape, torture and murder of ten young women in their rooming house, including her own daughter. In "The Mum Who Killed for Kicks" Perrini looks at the recent case of Joanne Dennehy, a mother of a thirteen-year old who inexplicably went on a thrill kill serial killing spree in which she tortured and murdered three men with a knife and attempted to kill two others.Kelly Banaski, a newcomer to true crime writing, brings us "Stripped of his medals and female panties", the strange case of a Canadian air force base commander, a colonel who piloted senior government officials and even the Queen of England, who suddenly began to commit a series of panty fetish burglaries that eventually escalated to horrific rape-torture murders of women. Enjoy and be horrified!!
An totally updated and revised edition to the most thorough guide to the Ocean State. Diminutive Rhode Island offers great diversity. Explore more than 400 miles of sandy beaches and rocky headlands, the splendid historic mansions of Newport, and the fine restaurants of Providence’s Federal Hill; enjoy the tranquil beauty of Block Island and fascinating museums and historic sites. Veteran travel writers Méras and Imbrie capture it all in this revised and expanded edition.
Proposing a new way to map intersections of photography and American literature, Katherine Henninger demonstrates the importance of pinpointing specific cultural and subcultural history. "Ordering the Facade" traces the visual and literary cultures of sou
Reflecting experiences gained while teaching in England, Italy, Korea, and Turkey, author Katherine Baccaro presents an eclectic collection of twenty-four short stories. The tales delve into one familys dysfunction, the difficulties of dating in Manhattan, and the mysteries of love. Discombobulated explores a variety of everyday themes and pulls on human emotions. In Borborygmus, the prim and proper thirty-seven- year-old Dermot McGreevy feels humiliated when he develops an embarrassing ailment. In The Department of Nosology, two thirteen-year- old girls suffer the consequences after they begin cataloging the noses of the townspeople. The Census explores the feelings of tourists in Turkey as they learn they will be banished to their hotel room for a day while the country conducts its census. From the comic to the sad, from real life to imagined landscapes, and from nostalgia and memories to suppositions and lies, Discombobulated offers a diverse collection of stories offering insight into the human condition.
Modern biological databases comprise not only data, but also sophisticated query facilities and bioinformatics data analysis tools. This book provides an exploration through the world of Bioinformatics Database Systems. The book summarizes the popular and innovative bioinformatics repositories currently available, including popular primary genetic and protein sequence databases, phylogenetic databases, structure and pathway databases, microarray databases and boutique databases. It also explores the data quality and information integration issues currently involved with managing bioinformatics databases, including data quality issues that have been observed, and efforts in the data cleaning field. Biological data integration issues are also covered in-depth, and the book demonstrates how data integration can create new repositories to address the needs of the biological communities. It also presents typical data integration architectures employed in current bioinformatics databases. The latter part of the book covers biological data mining and biological data processing approaches using cloud-based technologies. General data mining approaches are discussed, as well as specific data mining methodologies that have been successfully deployed in biological data mining applications. Two biological data mining case studies are also included to illustrate how data, query, and analysis methods are integrated into user-friendly systems. Aimed at researchers and developers of bioinformatics database systems, the book is also useful as a supplementary textbook for a one-semester upper-level undergraduate course, or an introductory graduate bioinformatics course.
A democracy falters when most of its citizens are uninformed or misinformed, when misinformation affects political decisions and actions, or when political actors foment misinformation—the state of affairs the United States faces today, as this timely book makes painfully clear. In Do Facts Matter? Jennifer L. Hochschild and Katherine Levine Einstein start with Thomas Jefferson’s ideal citizen, who knows and uses correct information to make policy or political choices. What, then, the authors ask, are the consequences if citizens are informed but do not act on their knowledge? More serious, what if they do act, but on incorrect information? Analyzing the use, nonuse, and misuse of facts in various cases—such as the call to impeach Bill Clinton, the response to global warming, Clarence Thomas’s appointment to the Supreme Court, the case for invading Iraq, beliefs about Barack Obama’s birthplace and religion, and the Affordable Care Act—Hochschild and Einstein argue persuasively that errors of commission (that is, acting on falsehoods) are even more troublesome than errors of omission. While citizens’ inability or unwillingness to use the facts they know in their political decision making may be frustrating, their acquisition and use of incorrect “knowledge” pose a far greater threat to a democratic political system. Do Facts Matter? looks beyond individual citizens to the role that political elites play in informing, misinforming, and encouraging or discouraging the use of accurate or mistaken information or beliefs. Hochschild and Einstein show that if a well-informed electorate remains a crucial component of a successful democracy, the deliberate concealment of political facts poses its greatest threat.
To Look Like America is designed to contribute a unique perspective to those interested in the challenges presented to public sector organizations -- particularly in the federal sector -- by an increasingly diverse workforce. Current projections are that the American workforce will become more and more diverse over the next decade, forcing employers to respond to real or perceived barriers to the participation and advancement of women and minorities in their organizations. This book provides a means for identifying and taking steps to dismantle such barriers. It shows how empirical measures can identify the extent to which such barriers exist. The measures are applied to a broad cross-section of the federal civil service through the use of employment, focus group, and interview data, as well as responses to surveys administered to representative samples of federal employees. The analysis examines the consequences that result when barriers are left unaddressed, and concludes with an assessment of interventions that can be effective in dismantling barriers and promoting true participation.
November, 1930. One sunny Saturday afternoon, 12-year-old Mena Griffiths was playing in the park when she was lured away by an unknown man. Hours later, her strangled body was found, mouth gagged and hands crossed over her chest, in an abandoned house. Only months later, another girl was murdered; the similarities between the cases undeniable. Crime in Melbourne had taken a shocking new turn: this was the work of a serial killer, a homicidal maniac. Despite their best efforts, police had no experience dealing with this kind of criminal. What followed was years of bungled investigations, falsely accused men - and the tragic deaths of two more girls - before the murderer was finally caught and brought to justice. With all the pace of a thriller, Katherine Kovacic recounts this extraordinary, chilling true story - of failed police enquiries, a killer with a Jekyll and Hyde personality, and the families shattered when four innocent lives were cruelly taken.
In Cape Light a troubled marriage is healed by a runaway teenager and a divorced woman finds happiness with a struggling magazine writer who dresses up as Santa Claus.
This book is a unique primer for school professionals, educators and policymakers to develop a solid understanding of the domains essential to cultivating and sustaining successful schools. It also provides essential reading for researchers interested in these issues more broadly. In response to various sensationalist discourses around schooling that dominate both mainstream and social media, the authors draw upon both long-standing and up-to-date research from around the world to present a more accurate, holistic, and optimistic approach. The book identifies the key domains that are necessary to address concerns in equity, leadership and teaching for enhanced student learning and wellbeing. Specifically, these domains relate to: (1) system-wide approaches to enhance school performance; (2) building teacher capability for student learning; (3) educational leadership as a vehicle for leading learning; and (4) building community ‘infrastructures’ for equitable, place-based learning. The book can be used in several ways: each chapter can be read as a stand-alone overview of key areas for school improvement. The broad topics are important jigsaw puzzle pieces that are necessary to ‘see the whole picture’ of a successful school/system. Each chapter includes ‘Key messages’ and ‘Ways forward’ and closes with extension questions to further guide thinking through the ‘big ideas’ presented in each chapter and how they are relevant to different schooling and policy contexts. Grounded in research into productive and proactive system and school practices from around the world, this book ensures professional educators are equipped with the latest research and practice, without being overwhelmed by the detail.
Discusses life and work of the popular children's author, including his writing process and methods, inspirations, a critical discussion of his books, biographical timeline, and awards.
In this important new work, two respected criminologists challenge the characterization of the new 'bad girl' arguing that it is only a new attempt to punish girls who are not the stereotypical depiction of good. Through interviews with young women, educators and people in the criminal justice system, Beyond Bad Girls exposes the formal and informal systems of socio-cultural control imposed on girls.
In the wake of Guantanamo Bay, extraordinary renditions, and secret torture centres in Eastern Europe and elsewhere, Revenge versus Legality addresses the relationship between law and wild or vigilante justice; between the power to enforce retribution and the desire to seek revenge. Taking up a variety of narratives from the eras of Romanticism, Realism, Modernism and the Contemporary period, and including new theories to explain the interactions that occur between legalistic courtroom justice and the vigilante variety, Revenge versus Legality analyzes some of the main obstacles to justice, ranging from judicial corruption, to racism and imperialism. The book culminates in a consideration of that form of crime or lawlessness that poses the most serious threat to the rule of law: vigilante justice masquerading as legality. With its mixture of politics, literature, law, and film, this lively and accessible book offers a timely reflection on the enduring phenomenon of revenge.
Each year, about 33 percent of all women and 3 percent of all men murdered in the United States, are killed by a so-called intimate, a spouse, partner, or lover. Nationwide, murder by an intimate is the number one cause of death for pregnant women. And murder by an intimate is not just an American problem. A European task force recently found domestic violence accounts for 25 percent of all homicides in London, and 35 percent across England and Wales. In this timely book, van Wormer and Roberts describe the problem, and what they have seen and heard on the front lines with both women and men who have escaped domestic violence that was escalating toward deadly levels. The text examines not only the psychology of the batterer but of domestic murder, and domestic murder-suicide. Drawn from the experience and insights of these two widely-known social workers, the text includes a safety plan for those at risk and a chapter providing narratives of women in prison for killing their abusive husband or partner. Drawing on the experience and insights of these two widely-known social workers, Death by Domestic Violence separates domestic violence myths and facts, explains the traumatic bonding that occurs between batterer and victim, and details how one facet of the solution could be school-based interventions and education. The book culminates with recommendations for further reduction of harm and a safety plan for those at risk.
When Henry Vizetelly was imprisoned in 1889 for publishing the novels of Émile Zola in English, the problem was not just Zola’s French candour about sex – it was that Vizetelly’s books were cheap, and ordinary people could read them. Censored exposes the role that power plays in censorship. In twenty-five chapters focusing on a wide range of texts, including the Bible, slave narratives, modernist classics, comic books, and Chicana/o literature, Matthew Fellion and Katherine Inglis chart the forces that have driven censorship in the United Kingdom and the United States for over six hundred years, from fears of civil unrest and corruptible youth to the oppression of various groups – religious and political dissidents, same-sex lovers, the working class, immigrants, women, racialized people, and those who have been incarcerated or enslaved. The authors also consider the weight of speech, and when restraints might be justified. Rich with illustrations that bring to life the personalities and the books that feature in its stories, Censored takes readers behind the scenes into the courtroom battles, legislative debates, public campaigns, and private exchanges that have shaped the course of literature. A vital reminder that the freedom of speech has always been fragile and never enjoyed equally by all, Censored offers lessons from the past to guard against threats to literature in a new political era.
How can you best help children with autism reach their full potential? Autism Spectrum Disorders (ASD) present a perplexing challenge for parents and school professionals. This essential resource was developed to respond directly to the difficulty school professionals and families face in selecting and applying appropriate interventions and treatments for the children in their care. The information is presented in a straightforward format, practical for finding answers to complex questions, and includes: A description of the intervention or treatment Reported benefits and effects associated with its use A synthesis of how the outcomes relate to individuals with ASD Potential costs and risks
Hollywood's conversion from silent to synchronized sound film production not only instigated the convergence of the film and music industries but also gave rise to an extraordinary period of songs in American cinema. Saying It With Songs considers how the increasing interdependence of Hollywood studios and Tin Pan Alley music publishing firms influenced the commercial and narrative functions of popular songs. While most scholarship on film music of the period focuses on adaptations of Broadway musicals, this book examines the functions of songs in a variety of non-musical genres, including melodramas, romantic comedies, Westerns, prison dramas, and action-adventure films, and shows how filmmakers tested and refined their approach to songs in order to reconcile the spectacle of song performance, the classical norms of storytelling, and the conventions of background orchestral scoring from the period of silent cinema. Written for film and music scholars alike as well as for general readers, Saying It With Songs illuminates the origins of the popular song score aesthetic of American cinema.
This scholarly close reading of Allen Ginsberg's "Howl" considers the iconic poem through a four-part trickster framework: appetite, boundlessness, transformative power and a proclivity for setting and falling victim to tricks and traps. The book pursues various different narratives of the trickster Coyote and the historical and biographical contexts of "Howl" from a truly interdisciplinary perspective. This study seeks to contribute to the current literature on the poetry of the Beats and of Allen Ginsberg, specifically his "Howl," and the ways it continues to expand in meaning, depth and significance today.
An irresistible and sweeping love story that follows two Portuguese refugees who flee religious violence and reignite their budding romance in Civil-War America. “Vaz's work is gorgeous at every level—singing sentences and pull-you-in plot. She is the real thing, an American treasure.” —Tayari Jones, New York Times bestselling author of An American Marriage John Alves, son of a famous Presbyterian martyr on the Portuguese island of Madeira, spends his childhood in jail and in poverty. When he meets Mary Freitas—though the adopted daughter of a master botanist, her true lineage is the subject of dangerous rumor—a spark kindles a lasting bond. But soon their families must confront the rising blood tide of warfare between Catholics and Protestants. Fleeing with only what they can carry, John and Mary are separated and arrive at different times and places in a rapidly growing and changing mid-nineteenth-century Illinois. Years later, John settles into his life as an educator at Jacksonville’s nationally renowned school for the deaf, and Mary is a gardener in Springfield for handsome, wealthy Edward Moore. After John and Mary reconnect, the home of rising politician Abraham Lincoln provides a prime setting for their courtship. But conflict looms on the horizon, and John is torn. Should he join the Union army to prove his loyalty to his new country, or should he stay to fight for the chance to make a life with the one he loves? And should Mary accept Edward’s marriage proposal since he is a partner in her business of selling the miracle-berry fruit she transported from Madeira, or should she choose her passion for John? Social jealousies and betrayals compound the obstacles unleashed by the Civil War. In poignant and lyrical prose, Katherine Vaz’s Above the Salt is a captivating and beautiful tribute to the power of true love and the sacrifices we make to harness it.
Family Theories: Foundations and Applications presents a comprehensive and accessible approach to the most current perspectives in the field of family theory. Integrates classic and contemporary writings on family theories Features compelling case studies drawn from the authors’ experiences working with thousands of students Represents an integrative use of theory, research, and practice Utilizes the metaphor of “developing your theory app” to translate complex academic ideas into accessible, student-friendly language
Praise for Working with Female Offenders "Encyclopedic in scope and full of very relevant work drawn from the fields of biology, psychology, criminology, and corrections, this book is a must-read for those working with girl and women offenders." —Meda Chesney-Lind, Professor, Women's Studies University of Hawaii at Manoa "In this timely and thoughtful book, van Wormer provides a gender-sensitive lens through which the reader can examine pathways to female criminality, a global perspective on female crime and punishment, and innovative treatment approaches. This book is a must-have for any student or professional who wishes to truly impact and empower the lives of female offenders." —David W. Springer, Associate Dean for Academic Affairs, School of Social Work The University of Texas at Austin "This book is timely in light of promising developments that are taking place at every level of the criminal justice system. It is a must-read for policymakers, practitioners, academics, and students in criminal justice, social work, and other related fields." —Barbara E. Bloom, Professor, Criminology and Criminal Justice Studies Sonoma State University, California The first book to combine elements from the social work, counseling, and crimi- nology fields to create a framework tailored to working with female offenders Taking into account the special needs of girls and women within a system designed by men for male offenders, Working with Female Offenders offers counselors, correctional officers, lawyers, probation officers—in short, anyone who works in some capacity with female offenders–an evidence-based, gentler approach for working effectively and successfully with girls and women in trouble with the law. Working with Female Offenders provides coverage devoted to the nature of female crime and to the institutional settings in which much of the female-specific programming is designed to take place. This timely volume equips professionals with proven counseling strategies tailored to fit this population. Practical guidelines are included for case management interventions, teaching skills of communication and assertiveness, and anger and stress management for female offender populations, as well as: A strengths/empowerment/restorative framework for counseling women in crisis Narratives from personal interviews with female offenders and correctional counselors Discussion of controversial topics such as prison homosexuality, AIDS in prison, girls in gangs, and women on death row Examples of successful, innovative programs for female offenders from the United States and abroad Working with Female Offenders addresses the unique challenges of female offenders and those who treat them, and provides a much needed addition to the literature on innovative programming for female offenders.
Exam Board: OCR Level: A-level Subject: Sociology First Teaching: September 2015 First Exam: June 2016 Build students' confidence to tackle the key themes of the 2015 OCR A-Level Sociology specification with this clear and accessible approach delivered by a team of leading subject authors. - Develop knowledge and understanding of key Year 1 concepts in a contemporary context, including globalisation and the digital social world - Strengthen essential sociological skills with engaging activities at every stage of the course - Reinforce learning and prepare for exams with practice and extension questions and exercises
The use of irony in music is just beginning to be defined and critiqued, although it has been used, implied and decried by composers, performers, listeners and critics for centuries. Irony in popular music is especially worthy of study because it is pervasive, even fundamental to the music, the business of making music and the politics of messaging. Contributors to this collection address a variety of musical ironies found in the ’notes themselves,’ in the text or subtext, and through performance, reception and criticism. The chapters explore the linkages between irony and the comic, the tragic, the remembered, the forgotten, the co-opted, and the resistant. From the nineteenth to twenty-first centuries, through America, Europe and Asia, this provocative range of ironies course through issues of race, religion, class, the political left and right, country, punk, hip hop, folk, rock, easy listening, opera and the technologies that make possible our pop music experience. This interdisciplinary volume creates new methodologies and applies existing theories of irony to musical works that have made a cultural or political impact through the use of this most multifaceted of devices.
Methods in Educational Research Methods in Educational Research is designed to prepare students for the real world of educational research. It focuses on scientifically-based methods, school accountability, and the professional demands of the twenty-first century, empowering researchers to take an active role in conducting research in their classrooms, districts, and the greater educational community. Like the first edition, this edition helps students, educators, and researchers develop a broad and deep understanding of research methodologies. It includes substantial new content on the impact of No Child Left Behind legislation, school reform, quantitative and qualitative methodologies, logic modeling, action research, and other areas. Special features to assist the teaching and learning processes include vignettes illustrating research tied to practice, suggested readings at the end of each chapter, and discussion questions to reinforce chapter content. Praise for the Previous Edition "A new attempt to make this subject more relevant and appealing to students. Most striking is how useful this book is because it is really grounded in educational research. It is very well written and quite relevant for educational researchers or for the student hoping to become one." -PsycCRITIQUES/American Psychological Association "I applaud the authors for their attempt to cover a wide range of material. The straightforward language of the book helps make the material understandable for readers." -Journal of MultiDisciplinary Evaluation
In this novel in Thomas Kinkade’s heartwarming series, the holiday season brings changes and challenges to many in Cape Light. But on one silent night, peace and harmony will prevail. Sophie Potter is grateful for so many happy years among her beloved apple trees. But her family insists that she can no longer live alone. So Sophie makes a deal to spend one last Christmas on Potter Orchard. Luckily, her grandson James arrives in time to help her make plans for the best holiday gathering Cape Light has ever seen. James isn’t planning on staying in Cape Light. An aspiring writer, he’s eager for adventure and plans to take off on a trip around the world. But once James meets Zoey Bates, he starts to understand that leaving Cape Light might cost him the greatest adventure of all—falling in love. Meanwhile, after more than fifteen years as Cape Light’s mayor, Emily Warwick has lost the election to her lifelong rival, Charlie Bates. Emily is delighted to have more time for her family, but when a group of citizens begin fighting to preserve the town’s character, Emily can’t shake her desire to protect her town. Soon she finds herself back on a familiar battleground with Charlie and her family. It’s not the place anyone wants to be. Especially on Christmas.
Religious ceremonies were an inseparable part of Aboriginal traditional life, reinforcing social, economic, and political values. However, missionaries and government officials with ethnocentric attitudes of cultural superiority decreed that Native dances and ceremonies were immoral or un-Christian and an impediment to the integration of the Native population into Canadian society. Beginning in 1885, the Department of Indian Affairs implemented a series of amendments to the Canadian Indian Act, designed to eliminate traditional forms of religious expression and customs, such as the Sun Dance, the Midewiwin, the Sweat Lodge, and giveaway ceremonies.However, the amendments were only partially effective. Aboriginal resistance to the laws took many forms; community leaders challenged the legitimacy of the terms and the manner in which the regulations were implemented, and they altered their ceremonies, the times and locations, the practices, in an attempt both to avoid detection and to placate the agents who enforced the law.Katherine Pettipas views the amendments as part of official support for the destruction of indigenous cultural systems. She presents a critical analysis of the administrative policies and considers the effects of government suppression of traditional religious activities on the whole spectrum of Aboriginal life, focussing on the experiences of the Plains Cree from the mid-1880s to 1951, when the regulations pertaining to religious practices were removed from the Act. She shows how the destructive effects of the legislation are still felt in Aboriginal communities today, and offers insight into current issues of Aboriginal spirituality, including access to and use of religious objects held in museum repositories, protection of sacred lands and sites, and the right to indigenous religious practices in prison.
A tumour suppressor gene is a gene that reduces the probability that a cell in a multicellular organism will turn into a tumor cell. A mutation or deletion of such a gene will increase the probability of the formation of a tumor. Unlike oncogenes, tumor suppressor genes generally follow the 'two-hit hypothesis', which implies that both alleles that code for a particular gene must be affected before an effect is manifested. This is due to the fact that if only one allele for the gene is damaged, the second can still produce the correct protein. However, there are cases where mutations in only one allele will cause an effect. A notable example is the gene that codes for p53. Tumor suppressor genes, or more precisely, the proteins for which they code, either have a dampening or repressive effect on the regulation of the cell cycle or promote apoptosis, and sometimes do both. This book presents new and important research from throughout the world.
Filled with updated information, equations, tables, figures, and citations, Environmental Investigation and Remediation: 1,4-Dioxane and Other Solvent Stabilizers, Second Edition provides the full range of information on 1,4-dioxane. It offers passive and active remediation strategies and treatment technologies for 1,4-dioxane in groundwater and provides the technical resources to help readers choose the best methods for their particular situation. This new edition includes all new information on remediation costs and reflects the latest research in the field. It includes new practical case studies to illustrate the concepts presented, including 1,4-dioxane occurrence in Long Island and the Cape Fear watershed in North Carolina. Features: Fully updated throughout to reflect the most recent research on 1,4-dioxane Describes the nature and extent of 1,4-dioxane releases, their regulation, and their remediation in a variety of geologic settings Examines 1,4-dioxane analytical chemistry, its many industrial uses, and 1,4-dioxane occurrence as a byproduct in production of many products Provides ample site data for recent and relevant remediation case studies, and a review of the widely varying regulatory landscape for 1,4-dioxane cleanup levels and drinking water limits Discusses the importance of accounting for contaminant archeology in investigating contaminated sites, and leveraging solvent stabilizers in forensic investigations While written primarily for practicing professionals, such as environmental consultants and attorneys, water utility engineers, and laboratory managers, the book will also appeal to researchers and academics as well. This new edition serves as a highly useful reference on the occurrence, sampling and analysis, and remedial investigation and design for 1,4-dioxane and related contaminants.
With the recent turn to science studies and interdisciplinary research in Shakespearean scholarship, Shakespeare and Science: A Dictionary, provides a pedagogical resource for students and scholars. In charting Shakespeare's engagement with natural philosophical discourse, this edition shapes the future of Shakespearean scholarship and pedagogy significantly, appealing to students entering the field and current scholars in interdisciplinary research on the topic alongside the non-professional reader seeking to understand Shakespeare's language and early modern scientific practices. Shakespeare's works respond to early modern culture's rapidly burgeoning interest in how new astronomical theories, understandings of motion and change, and the cataloging of objects, vegetation, and animals in the natural world could provide new knowledge. To cite a famous example, Hamlet's letter to Ophelia plays with the differences between the Ptolemaic and Copernican notions of the earth's movement: “Doubt that the sun doth move” may either be, in the Ptolemaic view, an earnest plea or, in the Copernican system, a purposeful equivocation. The Dictionary contextualizes such moments and scientific terms that Shakespeare employs, creatively and critically, throughout his poetry and drama. The focus is on Shakespeare's multiform uses of language, rendering accessible to students of Shakespeare such terms as “firmament,” “planetary influence,” and “retrograde.”
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.