Written by a leading expert on Aspirin-related research, this is the most comprehensive treaty of the history, pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This third completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention and treatment of cardiovascular diseases, thromboinflammation and colorectal cancer.
wThis book presents the first comprehensive typology of purpose clause constructions in the world’s languages. Based on a stratified variety sample of 80 languages, it uncovers the unity and diversity of the morphosyntactic means by which purposive relations are coded, and discusses the status of purpose clauses in the syntactic and conceptual space of complex sentences. Explanations for significantly recurrent coding patterns are couched in a usage-based approach to language structure, which pays due attention to the cognitive and communicative pressures on usage events involving purpose clauses, to frequency distributions of grammatical choices in corpora, and to the ways in which usage preferences conventionalize in pathways of diachronic change. The book integrates diverse previous strands of research on purpose clauses with a thorough empirical analysis in its own right and thus reflects the current state of the art of crosslinguistic research into this distinctive type of adverbial clause. An appendix to A Typology of Purpose Clauses can be found on the author's website: www.karsten-schmidtke.net/purpose
In Miami, Florida, seeking her younger sister, 16-year-old Ashline Wilde, a Polynesian volcano goddess, joins forces with other reincarnated deities. But trickster Colt's diabolical plans threaten them all.
This pathbreaking ethnography of population movements between rural and urban places in Peru addresses the conceptual and methodological problems of studying ‘deterritorialized' populations and the implications of this for anthropology's notions of culture and identity. Based on extensive fieldwork, this book explores the economic, social and ritual bonds which link migrants in Peru's major cities to their Andean native village. Many urban migrants establish networks based on kinship and marriage ties to exploit resources in the city as well as the village. These networks ensure they maintain strong links to their native village. Fiestas, soccer tournaments and folklore festivals also play a crucial role in the formation of migrant communities in Peru's cities. The author analyses these performance practices and shows how they give rise to the creation of new social identities. The participation of second generation migrants, returning migrants, and migrant spouses in village life is also discussed.
Peruvians Dispersed presents an anthropological study of transnational migration to the United States, Spain, Japan, and Argentina. Karsten Paerregaard spent one year living with Peruvian migrants on four continents. This experience allowed him to make ethnographic descriptions of Peru's migrant communities and to discuss how immigration and labor market policies in the Global North both thwart and spur migration from the Global South. The book also offers an innovative contribution to the methodological debate about multisited field research, which in recent years has become prominent among scholars studying processes of globalization, transnationalism, and multiculturalism. Because of the wide span of social groups in Peru that migrate and the global dispersion of Peruvians in America, Asia, and Europe, the study of Peruvian migration offers a unique opportunity to rethink current attempts to theorize transnational and diasporic migration and develop the methodological and analytical framework for a global ethnography. Peruvians Dispersed will be of interest to all levels of students of anthropology. Book jacket.
Challenging traditional accounts of the development of American private law, Peter Karsten offers an important new perspective on the making of the rules of common law and equity in nineteenth-century courts. The central story of that era, he finds, was a
When is a food 'traditional', 'artisanal', 'farmhouse' or 'country-style'? What is 'natural', 'authentic' and 'pure'? Find the answer between these book covers.
This unusual collection of 49 essays gives an overview of the trends and accomplishments of synthetic organic chemistry in recent years. Unique in its approach, it deals with almost every aspect of modern synthesis. The first part of the book describes methods and reagents, with particular emphasis on rapidly developing organometallic and biooriented procedures. In the second part, these tools are applied to the syntheses of interesting target compounds and natural compounds with remarkable physiological properties. Mechanistic discussions and retrosynthetic analyses are included. More than 1000 up-to-date references help the reader to pursue the topics highlighted here. This book gives both the active researcher and the advanced student insight into the competitive atmosphere, creativity, and resourcefulness so characteristic of organic synthesis today.
People often associate postwar Germany with technology and with its products of mass consumption, such as luxury cars. Even pop music, most notably Kraftwerk (literally 'power station') with songs such as Autobahn, Radioactivity or We are the Robots, disseminates the stereotype of a close link between German culture and technology. Technology in Modern German History explores various forms of technology in 200 years of German history and explains how technology has been fundamental to the shaping of modern Germany. The book investigates the role technology played in transforming Germany's culture, society and politics during the 19th and 20th centuries. Key topics covered include the different stages of industrialization, the growth of networked cities, and the triumph of a teleological narrative of technology as progress. Moreover, it provides a critical revision of the history of high technology which reveals how high-tech euphoria determined certain paths in history regardless of whether the respective technology proved to be successful. In its second part, the volume introduces new avenues in scholarship. Karsten Uhl examines neglected areas, such as rural technologies or the often-overlooked importance of everyday technologies: How did consumers or workers use new technologies? How did they appropriate and modify them? Lastly, the book considers the final decades of the 20th century and asks if they provided a significant new quality of technological change: To what degree and effects did computerization transform professional and private life in Germany? In culture and politics, reinforced by the German variety of environmentalism, the idea of progress was challenged, as the once prevailing vision of progress gave way to new apprehensions of uncertainty evident to this day. Technology in Modern German History brings fascinating insight into a much neglected area of German history for students and scholars alike.
Landscape Development and Climate Change in Southwest Bulgaria aims to address some of the current limitations in our understanding of past Balkan climate and environment. High mountains and their ecosystems offer an outstanding opportunity for studies on the impact of climate change. The Balkan Mountains in Southeast Europe, situated at the transition between temperate and Mediterranean climate, are considered as very sensitive to historical and current global changes. The geoarchives lake sediment, peat and soil, long living trees and glaciers have been used to reconstruct the climatically-driven change of forest and treeline during the Holocene and the younger past. These processes are interrelated with complex ecological changes, as for example the seasonality of climate parameters. The landscape research approach with the analyses through multi-palaeo-geoecological proxies is new for the Balkans.
This extensively updated second edition of LTE Signaling, Troubleshooting and Performance Measurement describes the LTE signaling protocols and procedures for the third generation of mobile communications and beyond. It is one of the few books available that explain the LTE signaling messages, procedures and measurements down to the bit & byte level, and all trace examples are taken for a real lab and field trial traces. This book covers the crucial key performance indicators (KPI) to be measured during field trials and deployment phase of new LTE networks. It describes how statistic values can be aggregated and evaluated, and how the network can be optimized during the first stages of deployment, using dedicated examples to enhance understanding. Written by experts in the field of mobile communications, this book systematically describes the most recent LTE signaling procedures, explaining how to identify and troubleshoot abnormal network behavior and common failure causes, as well as describing the normal signaling procedures. This is a unique feature of the book, allowing readers to understand the root cause analysis of problems related to signaling procedures. This book will be especially useful for network operators and equipment manufacturers; engineers; technicians; network planners; developers; researchers; designers; testing personnel and project managers; consulting and training companies; standardization bodies.
Walking the Big Wild is the story of Karsten Heuer's extraordinary 18-month journey of hiking, skiing, and paddling across 2100 miles of mountains, forests, and rivers from Yellowstone National Park in Wyoming to the Canadian Yukon. Accompanied by occasional human companions and a remarkable border collie named Webster, Heuer encountered immense challenges: storms, avalanches, floods, and grizzlies. At the end of the journey, Heuer proved that there is nearly continuous wilderness that can support wildlife along the length of the Rockies-and is salvageable if the right decisions are made now. Karsten Heuer has worked as a wildlife biologist and park warden in Banff National Park in the Rockies, in Inuvik in Canada's far north, and in the Madikwe Game Reserve in South Africa.
This book discusses the modeling and analysis of magnetic resonance imaging (MRI) data acquired from the human brain. The data processing pipelines described rely on R. The book is intended for readers from two communities: Statisticians who are interested in neuroimaging and looking for an introduction to the acquired data and typical scientific problems in the field; and neuroimaging students wanting to learn about the statistical modeling and analysis of MRI data. Offering a practical introduction to the field, the book focuses on those problems in data analysis for which implementations within R are available. It also includes fully worked examples and as such serves as a tutorial on MRI analysis with R, from which the readers can derive their own data processing scripts. The book starts with a short introduction to MRI and then examines the process of reading and writing common neuroimaging data formats to and from the R session. The main chapters cover three common MR imaging modalities and their data modeling and analysis problems: functional MRI, diffusion MRI, and Multi-Parameter Mapping. The book concludes with extended appendices providing details of the non-parametric statistics used and the resources for R and MRI data.The book also addresses the issues of reproducibility and topics like data organization and description, as well as open data and open science. It relies solely on a dynamic report generation with knitr and uses neuroimaging data publicly available in data repositories. The PDF was created executing the R code in the chunks and then running LaTeX, which means that almost all figures, numbers, and results were generated while producing the PDF from the sources.
This thesis investigates a new concept for the flexible design and verification of an ADCS for a nanosatellite platform. In order to investigate guidelines for the design of a flexible ADCS, observations of the satellite market and missions are recorded. Following these observations, the author formulates design criteria which serve as a reference for the conceptual design of the flexible ADCS. The research of the thesis was carried out during the development of TU Berlin's nanosatellite platform TUBiX20 and its first two missions, TechnoSat and TUBIN. TUBiX20 targets modularity, reuse and dependability as main design goals. Based on the analysis of design criteria for a flexible ADCS, these key design considerations for the TUBiX20 platform were continued for the investigations carried out in this thesis. The resulting concept implements the ADCS as a distributed system of devices complemented by a hardware-independent core application for state determination and control. Drawing on the technique of component-based software engineering, the system is partitioned into self-contained modules which implement unified interfaces. These interfaces specify the state quantity of an input or output but also its unit and coordinate system, complemented by a mathematical symbol for unambiguous documentation. The design and verification process for the TUBiX20 ADCS was also elaborated during the course of this research. The approach targets the gradual development of the subsystem from a purely virtual satellite within a closed-loop simulation to the verification of the fully integrated system on an air-bearing testbed. Finally, the concurrent realization of the investigated concept within the TechnoSat and TUBIN missions is discussed. Starting with the individual ADCS requirements, the scalability of the approach is demonstrated in three stages: from a coarse, but cost- and energy-efficient configuration to realize a technology demonstration mission with moderate requirements (TechnoSat) to a high-performance configuration to support Earth observation missions (TUBIN). Diese Dissertation untersucht ein neues Konzept zur flexiblen Entwicklung und Verifikation eines Lageregelungssystems für eine Nanosatellitenplattform. Als Grundlage für die Erarbeitung eines Leitfadens für die Entwicklung werden zunächst Beobachtung des Satellitenmarkts sowie konkreter Missionen zusammengetragen. Darauf aufbauend formuliert der Autor Entwurfskriterien für die Konzipierung eines flexiblen Lageregelungssystems. Die Dissertation wurde im Rahmen der Entwicklung der TUBiX20 Nanosatellitenplattform und ihrer ersten beiden Missionen, TechnoSat und TUBIN, an der TU Berlin durchgeführt. TUBiX20 verfolgt Modularität, Wiederverwendung und Zuverlässigkeit als Entwicklungsziele. Diese werden unter der Verwendung der vom Autor hergeleiteten Entwurfskriterien in dieser Arbeit im Kontext des Lageregelungssystems verfeinert. Das resultierende Konzept setzt dieses als verteiltes System von Geräten und einem hardware-unabhängigen Software-Kern um. Der Software-Entwurfstechnik Component-based software engineering folgend ist das System in unabhängige Module unterteilt, welche wiederum einheitliche Schnittstellen implementieren. Diese Schnittstellen spezifizieren die Zustandsgrößen für die Ein- und Ausgänge der Module inklusive Einheit, Koordinatensystem und mathematischem Symbol für eine eindeutige Darstellung. Der Entwurfs- und Verifikationsprozess für das TUBiX20 Lageregelungssystem wurde vom Autor im Rahmen der Arbeit untersucht. Hier verfolgt der Ansatz einen schrittweisen übergang von einem virtuellen Satelliten als Simulationsmodell bis hin zur Verifikation des integrierten Systems auf einem Lageregelungsteststand. Abschließend diskutiert die Arbeit die Realisierung des untersuchten Konzepts im Rahmen der Missionen TechnoSat und TUBIN. Beginnend mit den jeweiligen Anforderungen wird die Skalierbarkeit des Ansatzes in drei Stufen demonstriert: von einer groben, aber kosten- und energieeffizienten Konfiguration für eine Technologieerprobungsmission mit moderaten Anforderungen (TechnoSat) bis hin zu einer Konfiguration für hochgenaue Lageregelung als Basis für Erdbeobachtungsmissionen (TUBIN).
The urban morphology investigates settlement and urban forms. These do not change overnight, but in a process that follows certain principles. There is hardly anything more complex and contradictory than a city. Precisely because of this complexity, there is little agreement on definitions and procedural methods. This applies in particular to urban planning, which is not only concerned with analysis, but also with the design and transformation of cities. A variety of different urban morphological approaches exist today. The authors from the areas of research and practice investigate the relevance of the morphological perspective in the field of contemporary urban landscapes. They link historical roots and current approaches and explain the relationship between analysis and design.
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