3 books illuminate the cutting edge medical research that could save your life Right now, science is transforming what we know about preserving and improving human health. These three extraordinary books take you to the cutting edge of emerging science, presenting new findings that might someday save your life. In Antibiotic Resistance: Understanding and Responding to an Emerging Crisis, Karl S. Drlica and David S. Perlin presents a thorough and authoritative overview of the growing resistance of pathogenic bacteria to antibiotics, and what this means to our ability to control and treat infectious diseases. The authors answer crucial questions such as: What is resistance? How does it emerge? How do common human activities promote resistance? What can we do about it? How can we strengthen our defenses against resistance, minimize our risks, extend the effectiveness of current antibiotics, and find new ones faster? Next, in Chips, Clones, and Living Beyond 100: How Far Will the Biosciences Take Us?, Paul and Joyce A. Schoemaker tour the remarkable field of biosciences as it stands today, and preview the directions and innovations that are most likely to emerge in the coming years. They offer a clear, non-technical overview of crucial current developments that are likely to have enormous impact, addressing issues ranging from increased human longevity to global warming, bio-warfare to personalized medicine. Along the way, they illuminate each of the exciting technologies and hot-button issues associated with contemporary biotechnology - including stem cells, cloning, probiotics, DNA microarrays, proteomics, gene therapy, and more. Finally, in It Takes a Genome, Greg Gibson posits a revolutionary new hypothesis: our genome is out of equilibrium, both with itself and its environment. Our bodies weren’t designed to subsist on fat and sugary foods; our immune systems aren’t designed for today’s clean, bland environments; our minds aren’t designed to process hard-edged, artificial electronic inputs from dawn ‘til midnight. That, says Gibson, is why so many of us suffer from chronic diseases that barely touched our ancestors. Gibson reveals the stunningly complex ways genes cooperate and interact; illuminates the genetic “mismatches” that lead to cancer, diabetes, inflammatory and infectious diseases, AIDS, depression, and senility; and considers surprising new evidence for genetic variations in human psychology. From world-renowned leaders and experts, including Karl S. Drlica, David S. Perlin, Paul J. H. Schoemaker, Joyce A. Schoemaker, and Greg Gibson
Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.
3 remarkable books reveal the latest scientific discoveries about addiction, antibiotic-resistant disease, bacteria — and you These three remarkable books take you to the cutting edge of health science, revealing today’s most powerful scientific discoveries about addiction, antibiotic-resistant disease, and bacteria. In The Addicted Brain, leading neuroscientist Michael Kuhar, Ph.D. explains how and why addiction destroys lives, and presents the latest advances in treatment and prevention. Using breathtaking brain imagery and other research, Kuhar reveals the powerful, long-term brain changes that drugs can cause, explaining why it can be so difficult for addicts to escape them. He describes why some people are unusually susceptible to addiction; illuminates striking neural similarities between drugs and pleasures ranging from alcohol and gambling to sex and caffeine; and outlines the 12 characteristics most often associated with successful treatment. Next, in Antibiotic Resistance: Understanding and Responding to an Emerging Crisis, Karl S. Drlica and David S. Perlin presents a thorough and authoritative overview of the growing resistance of pathogenic bacteria to antibiotics, and what this means to our ability to control and treat infectious diseases. The authors answer crucial questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? Are there better ways to discover new antibiotics? How can we strengthen our defenses against resistance, minimize public health risks and extend the effectiveness of the antibiotics we have? Finally, in Allies and Enemies, Anne Maczulak tells the story of the amazing, intimate partnership between humans and bacteria. Offering a powerful new perspective on Earth’s oldest creatures, Maczulak explains how bacteria work, how they evolve, their surprising contributions and uses, the roles they’ve played in human history – and why you can't survive without them. From pioneering scientists and researchers including Michael Kuhar, Karl S. Drlica, David S. Perlin, and Anne Maczulak
This is the eBook version of the printed book. This Element is an excerpt from Antibiotic Resistance: Understanding and Responding to an Emerging Crisis (9780131387737) by Karl Drlica and David S. Perlin. Available in print and digital formats. What everyone needs to know about antibiotics: what they are, how they work, what they can do, and what they can’t do. Antibiotics are selective poisons. They are relatively small molecules (about 20-100 times the size of water molecules) that interfere with normal life processes of microbes and viruses. Human cells differ enough from pathogens for antibiotics to act selectively. For example, our cells lack walls, whereas bacterial cells have them. Consequently, penicillin, which blocks cell wall synthesis, is specific to bacteria....
This is the eBook version of the printed book. This Element is an excerpt from Antibiotic Resistance: Understanding and Responding to an Emerging Crisis (9780131387737) by Karl Drlica and David S. Perlin. Available in print and digital formats. The truth behind the headlines: What antibiotic resistance is, why it’s growing, and what this means to human health. As a global community, we have not considered antibiotics as a resource to be actively protected. Consequently, we use antibiotics in ways that directly lead to resistance. Changing those ways requires an understanding of antibiotic principles. We begin with a brief description of MRSA to illustrate a bacterial-based health problem....
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