Overcome the toughest clinical challenges in nephrology with the new 9th edition of Brenner/Rector’s The Kidney! A brand-new editorial team of Drs. Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S. L. Yu, and Barry M. Brenner,, together with a diverse list of international contributors bring you the latest knowledge and best practices on every front in nephrology worldwide. Brand-new sections on Global Considerations in Nephrology and Pediatric Nephrology, as well as new chapters on recent clinical trials, cardiovascular and renal risk prediction in chronic kidney disease, identification of genetic causes of kidney disease, and many others, keep you at the forefront of this rapidly growing, ever-changing specialty. Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices. Broaden your knowledge base with expert, dependable, comprehensive answers for every stage of your career from the most comprehensive, definitive clinical reference in the field! Prepare for certification or recertification with a review of the basic science that underpins clinical nephrology as well as a comprehensive selection of the most important bibliographical sources in nephrology. Visually grasp and better understand critical information with the aid of over 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Get internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors, all of whom are at the top and the cutting edge of your field. A new editorial team headed by Dr. Taal and hand-picked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. Access information quickly thanks to a new, reorganized format and supplemental figures, tables, additional references, and expanded discussions. Keep current with the rapid development of care and research worldwide. A new section, "Global Considerations", focuses on regions outside Europe and North America. Leading experts from Latin America, Africa, Near and Middle East, Indian Subcontinent, Far East, Oceania and Australia present their expert insights into specific conditions, as well as progress and challenges in the development of the specialty. Improve therapy and outcomes for children with renal disease. New to this edition, "Pediatric Nephrology" addresses renal pathologies that usually present in childhood and covers topics such as Maturation of Kidney Structure and Function; Fluid; Electrolyte and Acid-Base Disorders in Children; Diseases of the Kidney and Urinary Tract in Children; Dialysis in Children; and Kidney Transplantation in Children. Stay up to date with all the latest clinical information including recent clinical trials, genetic causes of kidney disease, and cardiovascular and renal risk prediction in chronic kidney disease.
Serving as both a student textbook and a professional reference/handbook, this volume explores the statistical methods of examining time intervals between successive state transitions or events. Examples include: survival rates of patients in medical studies, unemployment periods in economic studies, or the period of time it takes a criminal to break the law after his release in a criminological study. The authors illustrate the entire research path required in the application of event-history analysis, from the initial problems of recording event-oriented data to the specific questions of data organization, to the concrete application of available program packages and the interpretation of the obtained results. Event History Analysis: * makes didactically accessible the inclusion of covariates in semi-parametric and parametric regression models based upon concrete examples * presents the unabbreviated close relationship underlying statistical theory * details parameter-free methods of analysis of event-history data and the possibilities of their graphical presentation * discusses specific problems of multi-state and multi-episode models * introduces time-varying covariates and the question of unobserved population heterogeneity * demonstrates, through examples, how to implement hypotheses tests and how to choose the right model.
Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it ...The example-based approach is easy to follow and makes the book a very helpful desktop reference for many biostatistics methods."—Journal of Statistical Software Clinical Trial Data Analysis Using R and SAS, Second Edition provides a thorough presentation of biostatistical analyses of clinical trial data with step-by-step implementations using R and SAS. The book’s practical, detailed approach draws on the authors’ 30 years’ experience in biostatistical research and clinical development. The authors develop step-by-step analysis code using appropriate R packages and functions and SAS PROCS, which enables readers to gain an understanding of the analysis methods and R and SAS implementation so that they can use these two popular software packages to analyze their own clinical trial data. What’s New in the Second Edition Adds SAS programs along with the R programs for clinical trial data analysis. Updates all the statistical analysis with updated R packages. Includes correlated data analysis with multivariate analysis of variance. Applies R and SAS to clinical trial data from hypertension, duodenal ulcer, beta blockers, familial andenomatous polyposis, and breast cancer trials. Covers the biostatistical aspects of various clinical trials, including treatment comparisons, time-to-event endpoints, longitudinal clinical trials, and bioequivalence trials.
A brilliant narrative history tracing today’s troubles back to the grandiose imperial overreach of Great Britain and the United States. Kingmakers is the gripping story of how the modern Middle East came to be, as told through the lives of the Britons and Americans who shaped it. Some are famous (Lawrence of Arabia and Gertrude Bell); others infamous (Harry St. John Philby, father of Kim); some forgotten (Sir Mark Sykes, Israel’s godfather, and A. T. Wilson, the territorial creator of Iraq). All helped enthrone rulers in a region whose very name is an Anglo-American invention. The aim of this engrossing character-driven narrative is to restore to life the colorful figures who gave us the Middle East in which Americans are enmeshed today.
Comprehensive discussion of QTL mapping concepts and theory Detailed instructions on the use of the R/qtl software, the most featured and flexible software for QTL mapping Two case studies illustrate QTL analysis in its entirety
Put the world's most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector's The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. - Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. - Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. - Discussions of today's hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. - New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. - New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. - Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. - A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. - Board review-style questions to help you prepare for certification or recertification. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Put the world's most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector's The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. - Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. - Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. - Discussions of today's hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. - New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. - New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. - Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. - A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. - Board review-style questions to help you prepare for certification or recertification. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Smith, Hogan, & Ormerod's Criminal Law is rightly regarded as the leading doctrinal textbook on criminal law in England and Wales. The book owes its consistent popularity to its depth of analysis, breadth of coverage, and accessible style. Over fifty years since the publication of the first edition, Professor David Ormerod and Karl Laird continue the tradition set down by Professors Sir John Smith and Brian Hogan by producing a textbook of unrivalled quality. The text continues to be an invaluable resource for undergraduate students and an essential reference source for criminal law practitioners. Digital formats and resources The sixteenth edition is available for students and institutions to purchase in a variety of formats, and is supported by online resources. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks A selection of online resources accompany this text, including: - A selection of additional online chapters - A full bibliography arranged alphabetically and by chapter - Annual updates
Statistics of Financial Markets offers a vivid yet concise introduction to the growing field of statistical application in finance. The reader will learn the basic methods of evaluating option contracts, analysing financial time series, selecting portfolios and managing risks making realistic assumptions of the market behaviour. The focus is both on the fundamentals of mathematical finance and financial time series analysis and on applications to given problems of financial markets, thus making the book the ideal basis for lecturers, seminars and crash courses on the topic. For the third edition the book has been updated and extensively revised. Several new aspects have been included: new chapters on long memory models, copulae and CDO valuation. Practical exercises have been added, the solutions of which are provided in the book by S. Borak, W. Härdle and B. Lopez Cabrera (2010) ISBN 978-3-642-11133-4. “Both R and Matlab Code, together with the data, can be downloaded by clicking on the Additional Information tab labeled “R and Matlab Code,” which you will find on the right-hand side of the webpage.”
In its first English-language edition, this book introduces the many-faceted interactions of animal populations with their habitats. From soil fauna, ants and termites to small and large herbivores, burrowing mammals and birds, the author presents a comprehensive analysis of animals and ecosystems that is as broad and varied as all nature. Chapter 2 addresses the functional role of animals in landscape ecosystems, emphasizing fluxes of energy and matter within and between ecosystems, and the effects of animals on qualitative and structural habitat change. Discussion includes chapters on the role of animal population density and the impacts of native herbivores on vegetation and habitats from the tropics to the polar regions. Cyclic mass outbreaks of species such as the larch bud moth in Switzerland, the mountain pine beetle and the African red-billed weaver bird are described and analyzed. Other chapters discuss Zoochory – the dispersal of seeds by ants, mammals and birds – and the influence of burrowing animals on soil development and geomorphology. Consideration extends to the impact of feral domestic animals. Chapter 5 focuses on problems resulting from introduction of alien animals and from re-introduction of animal species to their original habitats, discusses the effects on ecosystems of burrowing, digging and trampling by animals. The author also addresses keystone species such as kangaroo rats, termites and beavers. Chapter 6 addresses the role of animals in landscape management and nature conservation, with chapters on the impact of newcomer species such as animals introduced into Australia, New Zealand and Europe, and the consequences of reintroduction of species to original habitat. It also discusses the carrying capacity of natural habit, public attitudes toward conversation and more. The final section ponders the effects of climate on interactions between animals and their habitats.
Criminal Law' is written with the needs of the student foremost in mind to provide, more than ever, as modern and as comprehensive an exposition of the criminal law as he or she could possibly require.
Too often in biostatistical research and clinical trials, a knowledge gap exists between developed statistical methods and the applications of these methods. Filling this gap, Clinical Trial Data Analysis Using R provides a thorough presentation of biostatistical analyses of clinical trial data and shows step by step how to implement the statistical methods using R. The book’s practical, detailed approach draws on the authors’ 30 years of real-world experience in biostatistical research and clinical development. Each chapter presents examples of clinical trials based on the authors’ actual experiences in clinical drug development. Various biostatistical methods for analyzing the data are then identified. The authors develop analysis code step by step using appropriate R packages and functions. This approach enables readers to gain an understanding of the analysis methods and R implementation so that they can use R to analyze their own clinical trial data. With step-by-step illustrations of R implementations, this book shows how to easily use R to simulate and analyze data from a clinical trial. It describes numerous up-to-date statistical methods and offers sound guidance on the processes involved in clinical trials.
This volume is a thorough and accessible guide to criminal law, providing invaluable extracts from key cases, statutes, and expert articles, which have been carefully selected to illuminate the core of criminal law. Ormerod and Laird expertly guide the reader through the various facets of the law while posing stimulating questions for students to investigate further and reflect upon.
With a growing number of scientists and engineers using JMP software for design of experiments, there is a need for an example-driven book that supports the most widely used textbook on the subject, Design and Analysis of Experiments by Douglas C. Montgomery. Design and Analysis of Experiments by Douglas Montgomery: A Supplement for Using JMP meets this need and demonstrates all of the examples from the Montgomery text using JMP. In addition to scientists and engineers, undergraduate and graduate students will benefit greatly from this book. While users need to learn the theory, they also need to learn how to implement this theory efficiently on their academic projects and industry problems. In this first book of its kind using JMP software, Rushing, Karl and Wisnowski demonstrate how to design and analyze experiments for improving the quality, efficiency, and performance of working systems using JMP. Topics include JMP software, two-sample t-test, ANOVA, regression, design of experiments, blocking, factorial designs, fractional-factorial designs, central composite designs, Box-Behnken designs, split-plot designs, optimal designs, mixture designs, and 2 k factorial designs. JMP platforms used include Custom Design, Screening Design, Response Surface Design, Mixture Design, Distribution, Fit Y by X, Matched Pairs, Fit Model, and Profiler. With JMP software, Montgomery’s textbook, and Design and Analysis of Experiments by Douglas Montgomery: A Supplement for Using JMP, users will be able to fit the design to the problem, instead of fitting the problem to the design. This book is part of the SAS Press program.
Fundamentally revising our understanding of the nature and intellectual contours of early English Protestantism, Karl Gunther argues that sixteenth-century English evangelicals were calling for reforms and envisioning godly life in ways that were far more radical than have hitherto been appreciated. Typically such ideas have been seen as later historical developments, associated especially with radical Puritanism, but Gunther's work draws attention to their development in the earliest decades of the English Reformation. Along the way, the book offers new interpretations of central episodes in this period of England's history, such as the 'Troubles at Frankfurt' under Mary and the Elizabethan vestments controversy. By shedding new light on early English Protestantism, the book ultimately casts the later development of Puritanism in a new light, enabling us to re-situate it in a history of radical Protestant thought that reaches back to the beginnings of the English Reformation itself.
With one new volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of botany. The present volume includes reviews on structural botany, plant taxonomy, physiology, genetics and geobotany.
Albrecht, a noted management consultant, speaker, and author, draws on his experiences working with organizations around the world to define what organizational intelligence is and how it can be developed. Taking a critical look at organizations that have and have not achieved organizational intelligence, including Disney, Apple, Ford, and NASA, he defines seven components of organizational intelligence and uses them to analyze situations and identify the kinds of conditions necessary to nurture organizational intelligence. He also identifies 17 dysfunctional syndromes that keep companies from mobilizing their collective brain power. Annotation copyrighted by Book News, Inc., Portland, OR
Criminal Law' is written with the needs of the student foremost in mind to provide, more than ever, as modern and as comprehensive an exposition of the criminal law as he or she could possibly require.
Smith, Hogan, & Ormerod's Criminal Law is rightly regarded as the leading doctrinal textbook on criminal law in England and Wales. Published in its first edition over fifty years ago, it continues to be a key text for undergraduates and an essential reference source for practitioners.
The 50th volume of Progress in Botany appears in new guise. In cooperation with Springer-Verlag we have changed from the less attractive typewriter composition to the direct reproduction of a manuscript which was writ ten by means of a text editing system and produced by a laser printer. We, the editors, should like to take the appearance of Volume 50 as the occasion for a few short remarks. Our younger readers are perhaps not aware that our Book Series was founded in 1931 by Fritz von Wettstein, based on the following thoughts and considerations, aptly formulated by him in the Preface to the first volume. "One of the greatest dangers threatening progress in the science of botany is the absolutely unbelievable growth in volume of the literature. The quality of journals, books and individual works that are daily sent to us makes it impossible for anyone person to maintain a general view of the progress made in botany in all the specialized fields, let alone to find time for results from associated su bjects. For varying reasons, every botanist must find this state of matters insupportable. Let us endeavor, in the general interest, to retain a wide background of knowledge, and not become limited specialists. The vitally necessary connections between the specialized fields can only flourish, or even exist, if the general view of botany as a whole can be maintained.
With one new volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of botany. The present volume in- cludes reviews on structural botany, taxonomy, geobotany, plant physiology, genetics, and floral ecology.
“A remarkable historical and geographical study” of a road linking Lexington and Maysville, Kentucky, and its influence on America (West Virginia History). Eighteenth-century Kentucky beckoned to hunters, surveyors, and settlers from the mid-Atlantic coast colonies as a source of game, land, and new trade opportunities. Unfortunately, the Appalachian Mountains formed a daunting barrier that left only two primary roads to this fertile Eden. The steep grades and dense forests of the Cumberland Gap rendered the Wilderness Road impassable to wagons, and the northern route extending from southeastern Pennsylvania became the first main thoroughfare to the rugged West, winding along the Ohio River and linking Maysville to Lexington in the heart of the Bluegrass. Kentucky’s Frontier Highway reveals the astounding history of the Maysville Road, a route that served as a theater of local settlement, an engine of economic development, a symbol of the national political process, and an essential part of the Underground Railroad. Authors Karl Raitz and Nancy O’Malley chart its transformation from an ancient footpath used by Native Americans and early settlers to a central highway, examining the effect that its development had on the evolution of transportation technology as well as the usage and abandonment of other thoroughfares, and illustrating how this historic road shaped the wider American landscape. “The authors demonstrate quite convincingly that rich local history lies along our roads. They unearthed an abundance of behind-the-scenes information that is invisible to us as we barrel down the highway. It should give all readers pause to consider how much more they could know about the places they travel through.” —Craig E. Colten, author of Perilous Place, Powerful Storms: Hurricane Protection in Coastal Louisiana “A very well researched and well-written book that makes a significant contribution to the study of American roads, U.S. settlement history, and Kentucky history in particular. The authors’ approach is broad and multifaceted, well organized, and keenly focused on the myriad aspects of an important path, the land and time it transits. This is a fine holistic study of an important and complex road and its many geographical and historical components.” —Drake Hokanson, author of Lincoln Highway: Main Street across America “This notable and ably-illustrated volume . . . captures the rigors of frontier Appalachian geography and the utter ingenuity of diverse peoples bent on moving west. The road is perhaps the greatest of American themes?it encapsulates freedom, mobility, possibility, escape, commerce, crime and calumny, adventure, and romance. Thank goodness we have these two able storytellers to give us the narrative of the Maysville Road.” —Paul F. Starrs, Regents & Foundation Professor of Geography (University of Nevada), and recipient, J.B. Jackson Prize, Association of American Geographers
THE INSTANT NEW YORK TIMES BESTSELLER "The most important thing that has been written to date about what is in front of the American people in the next presidential election." —Nicolle Wallace An extraordinary view into the politics of our times, Tired of Winning explores how Donald Trump remade the Republican Party in his own image—and the wreckage he’s left in his wake. Packed with new reporting, Tired of Winning: Donald Trump and the End of the Grand Old Party tracks Trump’s improbable journey from disgraced and defeated former president to the dominant force, yet again, in the Republican Party. From his exile in Mar-a-Lago, Donald Trump has become more extreme, vengeful, and divorced from reality than he was on January 6, 2021. His meddling damaged the GOP’s electoral prospects for third consecutive election in 2022. His legal troubles are mounting. Yet he re-emerged as the frontrunner for the 2024 Republican presidential nomination. Jonathan Karl has known Donald Trump since his days as a New York Post reporter in the 1990s, and he covered every day of Trump’s administration as ABC News’s chief White House correspondent. No one is in a better position to detail the former president’s quest for retribution and provide a glimpse at what the GOP would be signing up for if it once again chooses him as its standard bearer. In 1964, Ronald Reagan told Americans it was “a time for choosing.” Sixty years later, Republicans have their own choice to make: Are they tired of winning?
With contributions from authors around the globe, Research Handbook of Entrepreneurial Exit explores this most important phenomenon in the entrepreneurial journey. This book presents a comprehensive review of the current issues in entrepreneurial exits
Bartley and Radnitzky have done the philosophy of knowledge a tremendous service. Scholars now have a superb and up-to-date presentation of the fundamental ideas of evolutionary epistemology." --Philosophical Books
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.