Essentials of Chemical Biology Discover a detailed knowledge of concepts and techniques that shape this unique multi-discipline Chemical Biology is devoted to understanding the way that Biology works at the molecular level. This is a problem-driven multi-discipline, incorporating as it does Organic, Physical, Inorganic, and Analytical Chemistry alongside newer emerging molecular disciplines. In recent years, Chemical Biology has emerged as a vibrant and growing multi-discipline distinct from Biochemistry that is focused on the quantitative analyses of the structures and functions of biological macromolecules and macromolecular lipid assemblies, at first in isolation, then in vitro and in vivo. The second edition of the Essentials of Chemical Biology begins with a thorough introduction to the structure of biological macromolecules and macromolecular lipid assemblies, before moving on to the principles of chemical and biological synthesis, followed by descriptions of a comprehensive variety of research techniques and experimental methods. In addition, the second edition now includes new sections on the behaviour of biological macromolecules and macromolecular lipid assemblies in cells in vitro and in organisms in vivo. Given this, the second edition of the Essentials of Chemical Biology promises to cement itself as the leading introduction to Chemical Biology, incorporating descriptions of cutting-edge research wherever appropriate. Hence, readers of the second edition of the Essentials of Chemical Biology will find: a general expansion in understanding of basic molecular mechanisms in Biology moving towards cellular and organismal mechanisms entirely new chapters covering miniaturization and array technologies, Chemical Cell Biology, and the interface between Chemical Biology and Nanotechnology updates to chapters reflecting recent research developments an increased engagement with medical applications Essentials of Chemical Biology is ideal for advanced undergraduates or (post) graduate students in Chemical Biology and adjacent fields.
Full shooting scripts with commentary from creator Julian Fellowes highlighting key historical and dramatic details. Includes previously unseen material. The most successful British television drama of our time, the multi-award-winning Downton Abbey has become a national phenomenon in the U.S. as well. Created by Julian Fellowes—who received an Academy Award for his screenplay for the acclaimed Robert Altman motion picture, Gosford Park—Downton Abbey features stellar performances, ravishing sets and costumes, and, most importantly, absolutely riveting plots. Now the scripts for the entire first season have been collected in one volume, along with never before seen material, incisive commentary, and color photos that will completely immerse fans in the world of Downton Abbey. Praise for Downton Abbey “A deft balance of emotion, suspense and comedy.” —Daily Telegraph “The sets and costumes are ravishing, the attention to detail painstaking and the performances are brilliant. But above all, it’s a cracking story.” —The Times (London)\ “There is no mystery about the potency of this series, slathered in wit, powered by storytelling of a high order.” —The Wall Street Journal “A sumptuous, accomplished piece of television.” —The Guardian (UK)
Across the globe there are scores of beautiful and unusual works of art that are largely unseen or fail to receive the critical acclaim they deserve. Why? The Best Art You've Never Seen restores to view 100 wonderful treasures of world art. Ranging from Peru to Papua New Guinea, it uncovers neglected wonders in offbeat corners of the world or locked away in the store rooms of the world's great museums. Some are hidden accidentally: by a rock-fall, a shift in a trade route, or through the drift of history. Others are hidden deliberately, buried as loot or destroyed by hate - like the fabulous Mount Kailash Temple in India. Many are hidden by changes of taste, marginalized because they don't fit into established ideas of art - works by artists such as Norman Rockwell, Nek Chand, and Niki de St Phalle. Other great works, like the the dazzling Très Riches Heures manuscript and the Mona Lisa, are being virtually hidden by the demands of conservation. And there are penty of treasures still waiting to be revealed - the Q'in Emperor's tomb or Leonardo's lost fresco The Battle of Anghiari. Author and former museum director Julian Spalding takes you into a world of beautiful and arresting artifacts and reveals their amazing stories. He sets forth a surprising and unfamiliar alternative canon of works that offers a fresh and controversial take on the world of art.
Dwarfish Charlie Boylan carries a loaded pistol into the House of Commons. A can of worms waiting to be opened, he was a police spy for nearly forty years. He wants a pension and what he knows will get it! Did he, between Waterloo and Wellington's funeral, cause the Peterloo riot to happen? Was it Charlie who fingered the Cato Street Conspirators? Did Shelley really drown by accident? And at the opening of the Great Exhibition was it he who saved the Queen from being blown up? With dark undertones in its revelations of the orchestrated state repression that followed the Napoleonic Wars, A Very English Agent drives a horse, well, a donkey and cart, through the early years of the nineteenth century in a rumbustious, funny, sexy, teeming novel, worthy of the times it describes.
In this entertaining book the author identifies each of the old coaching inns which provide ample evidence of Amersham's importance as a stopping place on the great coach road from London to the Midlands. He traces the history of all the town's tanneries and proves that Weller's brewery is much older than previously believed and that its many maltings were selling vast quantities of malt to London brewers in the 17th century. He does not neglect the townspeople themselves, not least the Drakes of Shardeloes who dominated the political, religious and social life of Amersham for 350 years. Here he is able to draw on the unique knowledge of Barney Tyrwhitt Drake, a direct descendant. Julian Hunt's well-researched narrative is both comprehensive and easy to read. Splendidly illustrated, it is a significant contribution to the published history of Buckinghamshire and will be warmly welcomed in and around old Amersham itself.
Reprint of the original, first published in 1871. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
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