Agent-based computational modeling is changing the face of social science. This book argues that this powerful technique permits the social sciences to meet an explanation, in which one 'grows' the phenomenon of interest in an artificial society of interacting agents: heterogeneous, boundedly rational actors.
In the United States, routine smallpox vaccination ended in 1972. The level of immunity remaining in the U.S. population is uncertain, but is generally assumed to be quite low. Smallpox is a deadly and infectious pathogen with a fatality rate of 30 percent. If smallpox were successfully deployed as an agent of bioterrorism today, the public health and economic consequences could be devastating. Toward a Containment Strategy for Smallpox Bioterror describes the scientific results and policy implications of a simulation of a smallpox epidemic in a two-town county. The model was developed by an interdisicplinary team from the Johns Hopkins Bloomberg School of Public Health and the Brookings Institution Center on Social and Economic Dynamics, employing agent-based and other advanced computational techniques. Such models are playing a critical role in the crafting of a national strategy for the containment of smallpox by providing public health policymakers with a variety of novel and feasible approaches to vaccination and isolation under different circumstances. The extension of these techniques to the containment of emerging pathogens, such as SARS, is discussed. About the Authors Joshua M. Epstein and Shubha Chakravarty are with the Brookings Institution. Derek A. T. Cummings, Ramesh M. Singha, and Donald S. Burke are with the Johns Hopkins Bloomberg School of Public Health.
French government officials have long been known among Europeans for the special attention they give to the state of their population. In the first half of the nineteenth century, as Paris doubled in size and twice suffered the convulsions of popular revolution, civic leaders looked with alarm at what they deemed a dangerous population explosion. After defeat in the Franco-Prussian War in 1870, however, the falling birthrate generated widespread fears of cultural and national decline. In response, legislators promoted larger families and the view that a well-regulated family life was essential for France.In this innovative work of cultural history, Joshua Cole examines the course of French thinking and policymaking on population issues from the 1780s until the outbreak of the Great War. During these decades increasingly sophisticated statistical methods for describing and analyzing such topics as fertility, family size, and longevity made new kinds of aggregate knowledge available to social scientists and government officials. Cole recounts how this information heavily influenced the outcome of debates over the scope and range of public welfare legislation. In particular, as the fear of depopulation grew, the state wielded statistical data to justify increasing intervention in family life and continued restrictions on the autonomy of women.
A reader-friendly overview of the fundamentals in hip pathology and treatment presented by esteemed experts! Synopsis of Hip Surgery by renowned hip specialists Shane Nho, Joshua Harris, Brett Levine, and an impressive group of contributors provides a well-rounded perspective on the surgical and nonsurgical management of common to rare hip conditions. The generously illustrated clinical reference is both concise and comprehensive, not only encompassing the full age continuum but also a wide array of hip disorders such as congenital and degenerative issues and problems associated with sports injuries. The first seven chapters lay a solid foundation, covering hip anatomy, patient history, physical examination, radiographic imaging, diagnostic tests, biomechanics, pathomechanics, and implant biology. Subsequent chapters detail prevalent conditions such as femoroacetabular impingement syndrome, hip dysplasia, soft-tissue injuries, and osteoarthritis. The text also covers less common diseases including synovial proliferative disorders, primary and metastatic tumors, and osteonecrosis. Procedure-specific chapters focus on primary and revision total hip arthroplasty and hip replacement surgery. Key Features An outline format and bulleted text provide a quick, easy reference for trainees and practitioners to consult prior to conferences, at the office, and in the operating room Over 200 color illustrations enhance understanding of impacted anatomy and procedures Fractures of the pelvis and hip including intracapsular, extracapsular, and acetabulum Discussion of pediatric conditions including Legg-Calvé-Perthes disease, slipped capital femoral epiphysis, and hip fractures This concise resource is essential reading for orthopaedic surgery residents, orthopaedic sports medicine and adult reconstruction fellows, general orthopaedic surgeons, and hip specialists.
Treatment of articular cartilage pathology in the knees of young and active patients is a challenging and controversial issue. Biologic Knee Reconstruction: A Surgeon's Guide is a how-to, step-by-step guide that addresses the evaluation and management of this unique patient population. Internationally renowned cartilage experts Dr. Brian J. Cole and Dr. Joshua D. Harris, along with their contributors, present information on normal and abnormal history and physical examination. The reader will learn proper decision-making using a patient-centered approach of treatment, increasing the likelihood of a successful outcome. In addition to radiographic assessment of articular cartilage, Biologic Knee Reconstruction discusses the use of biomarkers, defect classification, and patient-reported and surgeon-measured outcomes. Aggressive nonsurgical medical management, including medications, injections, physiotherapy, and rehabilitation, is also presented. Biologic Knee Reconstruction also discusses the management of concomitant pathologies such as malalignment, meniscal deficiency, and ligamentous instability. Selection of surgical cartilage restorative treatment options is multifactorial, requiring consideration of several patient-, knee-, and defect-specific issues. All contemporary open and arthroscopic cartilage techniques are presented in detail with high resolution figures. A unique feature of Biologic Knee Reconstruction is the presentation of several chapters discussing non-medical issues highly pertinent to the advancement and future of this field: funding of research and cost of new advanced technologies, regulation of advanced cellular, tissue, and genetic technologies, evidence-based medicine and clinical trial design and conduct, and the ethics of allograft tissues and stem cell use. Features: Technique preference cards from the experts performing cartilage surgery Patient education information The most up-to-date descriptions of advanced cartilage techniques Unique chapters not covered in books elsewhere, including: Biomarkers Patient-reported outcomes assessment Newer injection techniques (PRP, stem cells) One- and two-stage open and arthroscopic techniques using chondrocyte- and stem cell based cell therapies Costs and public and private funding of research Barriers to high-quality randomized trials Governmental regulation and availability/accessibility to patients Gene therapy and tissue engineering Ethics of articular cartilage surgery with stem cells, ex-vivo cell manipulation, and juvenile tissue sources With the most up-to-date content and step-by-step methods for surgical procedures, Biologic Knee Reconstruction: A Surgeon's Guide is the perfect addition to the bookshelf of the orthopedic surgeon, cartilage researcher, sports physical therapist, or athletic trainer who evaluates and manages this unique patient population.
With the release of ChatGPT, large language models (LLMs) have become a prominent topic of international public and scientific debate. The genie is out of the bottle, but does it have a mind? Can philosophical considerations help us to work out how we can live with such smart machines? In this book, distinguished philosophers explore questions such as whether these new machines are able to act, whether they are social agents, whether they have communicative skills, and if they might even become conscious. The book includes contributions from Syed AbuMusab, Constant Bonard, Stephen Butterfill, Daniel Dennett, Paula Droege, Keith Frankish, Frederic Gilbert, Ying-Tung Lin, Sven Nyholm, Joshua Rust, Eric Schwitzgebel, Henry Shevlin, Anna Strasser, Alessio Tacca, Michael Wilby, and a graphic novel by Anna and Moritz Strasser as a bonus
How to get more innovation and more equality. Is economic inequality the price we pay for innovation? The amazing technological advances of the last two decades—in such areas as artificial intelligence, genetics, and materials—have benefited society collectively and rewarded innovators handsomely: we get cool smartphones and technology moguls become billionaires. This contributes to a growing wealth gap; in the United States; the wealth controlled by the top 0.1 percent of households equals that of the bottom ninety percent. Is this the inevitable cost of an innovation-driven economy? Economist Joshua Gans and policy maker Andrew Leigh make the case that pursuing innovation does not mean giving up on equality—precisely the opposite. In this book, they outline ways that society can become both more entrepreneurial and more egalitarian. All innovation entails uncertainty; there's no way to predict which new technologies will catch on. Therefore, Gans and Leigh argue, rather than betting on the future of particular professions, we should consider policies that embrace uncertainty and protect people from unfavorable outcomes. To this end, they suggest policies that promote both innovation and equality. If we encourage innovation in the right way, our future can look more like the cheerful techno-utopia of Star Trek than the dark techno-dystopia of The Terminator.
Designed for busy clinicians struggling to fit the critical issue of nutrition into their routine patient encounters, Nutrition in Clinical Practice translates the robust evidence base underlying nutrition in health and disease into actionable, evidence-based clinical guidance on a comprehensive array of nutrition topics. Authoritative, thoroughly referenced, and fully updated, the revised 4th edition covers the full scope of nutrition applications in clinical practice, spanning health promotion, risk factor modification, prevention, chronic disease management, and weight control – with a special emphasis on providing concisely summarized action steps within the clinical workflow. Edited by Dr. David L. Katz (a world-renowned expert in nutrition, preventive medicine, and lifestyle medicine) along with Drs. Kofi D. Essel, Rachel S.C. Friedman, Shivam Joshi, Joshua Levitt, and Ming-Chin Yeh, Nutrition in Clinical Practice is a must-have resource for practicing clinicians who want to provide well-informed, compassionate, and effective nutritional counseling to patients.
Problems in Contract Law: Cases and Materials, by Charles L. Knapp, Nathan M. Crystal, Harry G. Prince, Danielle K. Hart, and Joshua M. Silverstein, includes cases with notes and explanatory text, additional commentary, essay, and short-answer problems, and multiple-choice review questions for each chapter. The cases selected are a balance of traditional and contemporary that reflect the development and complexity of contract law. Explanatory notes and text place the classic and newer decisions in their larger legal context. Questions and problems provide opportunities to practice core legal skills and encourage students to explore the relationship between theory and practice. This successful book is well known for approaching contract law and theory from multiple perspectives and using a variety of contractual settings. Adaptable for instructors with different pedagogical philosophies, Problems in Contract Law can easily be used in teaching by traditional case analysis, through problem-based instruction, or using theoretical inquiry. The purchase of this ebook edition does not entitle you to receive access to the Connected eBook with Study Center on CasebookConnect. You will need to purchase a new print book to get access to the full experience, including: lifetime access to the online ebook with highlight, annotation, and search capabilities; practice questions from your favorite study aids; an outline tool and other helpful resources. New to the 10th Edition: Five new principal cases that reflect advances in or improved statements of contract law. One restored principal case (Oppenheimer & Co. v. Oppenheim, Appel, Dixon & Co.) that provides valuable perspectives on a fundamental area of contract law. Twelve new problems, including several shorter problems, to provide more review options for teachers and students and to add contemporary fact patterns. Eight new tables and flow charts to assist students with the conceptual structure of complicated legal subjects. Editing of note and text material to reduce length without affecting coverage and to capture new legal developments. Reorganization of text and comment material to focus comments primarily on historical developments, allowing professors greater flexibility in assigning or deleting comments. Student accessibility to deleted cases from prior editions through Casebook Connect, allowing professors the further flexibility of continuing to easily assign cases for which they have a particular preference. Professors and students will benefit from: The authors’ emphasis on making the material accessible for both students taking and professors teaching the course - rejecting a hide-the-ball approach. The continued appeal to professors with various teaching methodologies: traditional, problem-oriented, theoretical, and practical. The comprehensive nature of the contents allows professors the flexibility to teach their students the basics or conduct a more in-depth analysis of a given topic. The continued mixture of classic and contemporary cases. Review questions at the end of each chapter that are primarily designed for students to perform self-assessments of their grasp of the material. Answers with explanations are included in an appendix within the book.
This volume provides an analysis of what we know about turning around "failing" schools in the United States. It starts with an in-depth examination of the barriers that hinder action on turnaround work. The book analyses the reasons why some schools that find themselves in serious academic trouble fail in their efforts to turn themselves around. Beginning with a discussion of what may best be described as "lethal" reasons or the most powerful explanation for failed reform initiatives, which include an absence of attention to student care and support; a near absence of attention to curriculum and instruction; the firing of the wrong people. Covered in this volume are "critical" explanations for failed turnaround efforts such as failure to attend to issues of sustainability, and "significant" explanations for failed turnaround efforts such as the misuse of test data. The volume concludes by examining what can be done to overcome problems that cause failure for turnaround schools and reviewing ideas in the core technology of schooling: curriculum, instruction, and assessment. As well as exploring problems associated with the leadership and management of schools to see where improvement is possible and an analysis of opportunities found in relationships between schools and their external partners such as parents and community members.
Guaranteed nonstop thriller. What Goes Around Comes Around is a perfect, powerful page-turner. It will keep you laughing. Very exciting and on the edge. Wild and suspenseful. A nail-biting must-read. It will draw you deep into the story and trigger your emotions. Like a good movie, you will think you are the character. Turned up with sex, passion, and revenge! Promise, you will love and enjoy. This is a book that will be talked about forever!
Treatment of articular cartilage pathology in the knees of young and active patients is a challenging and controversial issue. Biologic Knee Reconstruction: A Surgeon's Guide is a how-to, step-by-step guide that addresses the evaluation and management of this unique patient population. Internationally renowned cartilage experts Dr. Brian J. Cole and Dr. Joshua D. Harris, along with their contributors, present information on normal and abnormal history and physical examination. The reader will learn proper decision-making using a patient-centered approach of treatment, increasing the likelihood of a successful outcome. In addition to radiographic assessment of articular cartilage, Biologic Knee Reconstruction discusses the use of biomarkers, defect classification, and patient-reported and surgeon-measured outcomes. Aggressive nonsurgical medical management, including medications, injections, physiotherapy, and rehabilitation, is also presented. Biologic Knee Reconstruction also discusses the management of concomitant pathologies such as malalignment, meniscal deficiency, and ligamentous instability. Selection of surgical cartilage restorative treatment options is multifactorial, requiring consideration of several patient-, knee-, and defect-specific issues. All contemporary open and arthroscopic cartilage techniques are presented in detail with high resolution figures. A unique feature of Biologic Knee Reconstruction is the presentation of several chapters discussing non-medical issues highly pertinent to the advancement and future of this field: funding of research and cost of new advanced technologies, regulation of advanced cellular, tissue, and genetic technologies, evidence-based medicine and clinical trial design and conduct, and the ethics of allograft tissues and stem cell use. Features: Technique preference cards from the experts performing cartilage surgery Patient education information The most up-to-date descriptions of advanced cartilage techniques Unique chapters not covered in books elsewhere, including: Biomarkers Patient-reported outcomes assessment Newer injection techniques (PRP, stem cells) One- and two-stage open and arthroscopic techniques using chondrocyte- and stem cell based cell therapies Costs and public and private funding of research Barriers to high-quality randomized trials Governmental regulation and availability/accessibility to patients Gene therapy and tissue engineering Ethics of articular cartilage surgery with stem cells, ex-vivo cell manipulation, and juvenile tissue sources With the most up-to-date content and step-by-step methods for surgical procedures, Biologic Knee Reconstruction: A Surgeon's Guide is the perfect addition to the bookshelf of the orthopedic surgeon, cartilage researcher, sports physical therapist, or athletic trainer who evaluates and manages this unique patient population.
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