On February 11, 1907, the steamship Larchmont collided with the schooner Harry Knowlton. Thrown from their bunks, passengers of the Larchmont panicked and ran onto the ship's deck. Haphazardly loaded lifeboats set out only partially full, and shrieks from those left behind were heard in the distance. Nearly 150 passengers were lost that night. The men and women of Block Island courageously aided those in need and dealt with the horrors that washed ashore. Controversy swirled around the conduct of the captain and crew of the Larchmont as investigators tried to determine who was responsible for the collision. Authors Joseph and Janice Soares chronicle one of the greatest disasters in New England's waters.
Westerly is a stunning coastal community located in Rhode Island's southwest corner. It is rich in history, being the first town incorporated in the King's Province and the fifth town in the colony. These pages offer a glimpse of everyday life in old Westerly as well as amusing mishaps and historical events that have been hidden until now. Many colonial patriots, such as Benjamin Franklin, left their footprints upon the sandy soil of this tranquil place. Westerly also abounds with commercial heritage, such as the shipbuilding industry on the banks of the Pawcatuck River and the granite industry, which made Westerly famous. In addition this volume captures the tragic events that touched the majestic shores and strong citizens of Westerly.
Mucins are glycoproteins that are expressed in cells of different types and fulfill multiple functions that determine participation of these proteins in such processes as signal transduction, regulation of gene expression, cell proliferation, embryogenesis, cell differentiation, immunity, apoptosis and cancer development. This E-book series on mucins presents critical reviews on modern data concerning structures and functions of mucins, their roles in cell physiology and pathology as well as molecular aspects of therapy of mucin-associated diseases. Mucins are represented by two types of molecules: secreted mucins and membrane-bound (receptor) mucins. This e-book series represents a unique attempt to describe the molecular nature of mucin multifunctionality in separate volumes. Chapters in each volume demonstrate the central role of mucins as connectors and regulators of different signaling pathways and their participation metastatic processes. Clinical aspects of mucins, such as their role as diagnostic markers as well as possible applications in mucin-based immuno- and gene-therapies are also discussed. This is the first volume of the series. This volume introduces readers to the general properties of mucins, followed by chapters on specific variants of gel-forming and soluble mucins. The volume concludes with information on the functions of secreted mucins.
Here’s the most clinically oriented critical care text focusing on the adult patient. In full-color and superbly illustrated with clinical photographs, imaging studies, and management algorithms, and with a broad multidisciplinary focus, this text will help you enhance your skills at any level of training. Stands alone as a clinically oriented comprehensive reference. Completely updated and authorship expanded to reflect the evolution in critical care practice. In color for the first time, with new color schematics and treatment algorithms for greater ease of reference. Utilizes key points lists at the end of chapter, to help you make decisions rapidly and easily. Delivers key references that list other useful resources for information. Learn from the best ICU specialists worldwide with contributions from an increased number of international authorities. Effectively manage common complications in the ICU with updated coverage of severe sepsis, septic shock, surgical infections, neurogenic and anaphylactic shock, severe heart failure, acute coronary syndromes, and Acute Respiratory Distress Syndrome. Access the complete contents online at Expert Consult, along with an image bank and instructional videos!
In honor of George Washington and the colonists' separation from the king's rule, the territory once known as Kings County was renamed Washington County. Rich in history, this once densely wooded region was transformed, and by the dawn of the 20th century, many villages and hamlets had taken root. In the early 1900s, photographer Walter Rogers captured the evolution of this area, and the images in Washington County are all drawn from his collection of glass-plate negatives. The text originates from historic accounts during this period. Readers will encounter pirate treasure in Richmond, sea serpents, Kickapoo Indian medicine men, village mishaps, and more.
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