Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
Bridge the gap between ophthalmology and pathology with the 8th Edition of this comprehensive, easy-to-understand reference from Drs. Myron Yanoff and Joseph W. Sassani. Designed to keep you up to date with every aspect of the field, from current imaging techniques to genetics and molecular biology to clinical pearls, Ocular Pathology provides the concise yet complete information you need for board exams and clinical practice. - Includes new coverage of genetics and molecular biology, complications in diabetes mellitus, and the role of new drugs and other treatments for macular degeneration. - Covers the latest imaging techniques, including optical coherence tomography (OCT), anterior segment OCT (AS-OCT) and OCT-angiography. - Contains new images throughout that provide updated correlations between pathological and clinical aspects of each disorder. Clinicopathological correlations are presented with side-by-side image comparisons to make clinical pearl boxes even more useful. - Features more than 1,900 illustrations from the collections of internationally renowned leaders in ocular pathology. - Presents information in a quick-reference outline format – ideal for today's busy physician.
With applications using SmartPLS —the primary software used in partial least squares structural equation modeling (PLS-SEM)—this practical guide provides concise instructions on how to use this evolving statistical technique to conduct research and obtain solutions. Featuring the latest research, new examples, and expanded discussions throughout, the Second Edition is designed to be easily understood by those with limited statistical and mathematical training who want to pursue research opportunities in new ways. Please note that all examples in this Second Edition use SmartPLS 3. To access this software, please visit
This book is a celebration of Betty Joseph's work, and the work of a group of analysts who have joined her to think about particular kinds of difficulties encountered in the analytic situation, and to think about technical issues.
Comprehensive, yet concise and clinically oriented, the new edition of Ocular Pathology brings you the very latest advances of every aspect of ocular pathology. From updated information on today’s imaging techniques, to the implementation of genetic data to better understand disease, this esteemed medical reference book promises to keep you at the forefront of your field. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Take advantage of clinical "pearls" that offer you the benefits of proven strategies. Quickly reference information with help from a convenient outline format, ideal for today’s busy physician. Visualize every concept by viewing 1,900 illustrations, 1,600 of which are in full color, from the collections of internationally renowned leaders in ocular pathology. Understand the role of VEGF and other factors in the pathobiology of diabetic complications, as well as the pathobiology of myocilin and the TIGR gene in the development of glaucoma. Review the latest features related to the pathobiology of central corneal thickness. Stay abreast of the latest in ocular pathology with coverage of the classification system for retinoblastoma; immunopathology of herpes keratitis; and genetic features of persistent hyperplastic primary vitreous.
Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors' popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. - Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. - Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. - Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. - Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. - Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.
Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.
The Third Edition of A Primer on Partial Least Squares Structural Equation Modeling (PLS-SEM) guides readers through learning and mastering the techniques of this approach. The authors use their teaching experience to communicate the fundamentals of PLS-SEM with limited emphasis on equations and and symbols, relying on straightforward language instead.
Neurology in Clinical Practice brings you the most current clinical neurology through a comprehensive text, detailed color images, and video demonstrations. Drs. Daroff, Fenichel, Jankovic and Mazziotta, along with more than 150 expert contributors, present coverage of interventional neuroradiology, neurointensive care, prion diseases and their diagnoses, neurogenetics, and many other new developments. Online at www.expertconsult.com, you’ll have access to a downloadable image library, videos, and the fully searchable text for the dynamic, multimedia content you need to apply the latest approaches in diagnosis and management. Find answers easily through an intuitive organization by both symptom and grouping of diseases that mirrors the way you practice. Diagnose and manage the full range of neurological disorders with authoritative and up-to-date guidance. Refer to key information at-a-glance through a full-color design and layout that makes the book easier to consult. Access the fully searchable text online at www.expertconsult.com, along with downloadable images, video demonstrations, and reference updates. Stay current on advances in interventional neuroradiology, neurointensive care, prion diseases, neurogenetics, and more. See exactly how neurological disorders present with online videos of EEG and seizures, movement disorders, EMG, cranial neuropathies, disorders of upper and lower motor neurons. Keep up with developments in the field through significant revisions to the text, including brand-new chapters on neuromodulation and psychogenic disorders and a completely overhauled neuroimaging section. Tap into the expertise of more than 150 leading neurologists-50 new to this edition.
Regarded as the most authoritative surgical atlas in the field, Hinman’s Atlas of Urologic Surgery brings you the detailed visual guidance and unmatched expertise you need to confidently perform virtually any urologic surgical procedure. Detailed color illustrations and clinical photographs — accompanied by commentary from leading urologists—lead you step by step through each technique. Instructions and commentary from a veritable "who’s who" in urologic surgery equip you to successfully deliver optimal results. Know what to do and expect with comprehensive coverage of nearly every surgical procedure you might need to perform. Get a true-to-life view of each operation through illustrations, full-color photographs. Find answers fast thanks to a quick, clear, and easy-to-use format - ideal for residents as well as experienced surgeons. Turn to the companion reference, Hinman’s Atlas of UroSurgical Anatomy, 2nd Edition, for a more in-depth view of the complex structures you must navigate when performing any procedure. Master the latest techniques with new and revised chapters on laparoscopic urologic surgery, robotic-assisted laparoscopic prostatectomy, decision making in hypospadius surgery, Holmium: YAG laser treatment of benign prostatic disease, urethral sling for male and female incontinence, suture techniques, vascular surgery, and many other timely topics and recent advancements. Get all the accuracy, expertise, and dependability you could ask for from new editors who are among the most important names in urology, for expert guidance and a fresh understanding of the subject. Avoid pitfalls and achieve the best outcomes thanks to a step-by-step approach to each procedure, complete with commentary, tips, and tricks of the trade from leading experts.
The detailed illustrations in Hinman's Atlas of UroSurgical Anatomy, supplemented by radiologic and pathologic images, help you clearly visualize the complexities of the genitourinary tract and its surrounding anatomy so you can avoid complications and provide optimal patient outcomes. This medical reference book is an indispensible clinical tool for Residents and experienced urologic surgeons alike. Elsevier does not support access to Expert Consult for institutional customers.
Depend on Hinman's for up-to-date, authoritative guidance covering the entire scope of urologic surgery. Regarded as the most authoritative surgical atlas in the field, Hinman's Atlas of Urologic Surgery, 4th Edition, by Drs. Joseph A. Smith, Jr., Stuart S. Howards, Glenn M. Preminger, and Roger R. Dmochowski, provides highly illustrated, step-by-step guidance on minimally invasive and open surgical procedures, new surgical systems and equipment, and laparoscopic and robotic techniques. New chapters keep you up to date, and all-new commentaries provide additional insight from expert surgeons. - Provides access to procedural videos online, including Percutaneous Renal Cryotherapy, Greenlight Photovaporization of the Prostate, Holmium Laser Enucleation of the Prostate, Cryoablation of a Renal Tumor, and Sling Procedures in Women. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, videos, and references from the book on a variety of devices. - Features 10 new chapters, including Radical Cystectomy in the Male, Robotic Urinary Diversion, Laparoscopic and Robotic Simple Prostatectomy, Transrectal Ultrasound-Directed Prostate Biopsy, Transperineal Prostate Biopsy, Prostate Biopsy with MRI Fusion, Focal Therapies in the Treatment of Prostate Cancer, Brachy Therapy, Male Urethral Sling, and Botox Injection for Urologic Conditions. - Includes new commentaries in every chapter from today's leading urologists. - Offers a step-by-step incremental approach, highlighted by new illustrations, photos, and images. - Keeps you current with significant revisions to all female sling chapters, urethroplasty chapters, and more. - Helps you find what you need quickly with a clear, easy-to-use format – now reorganized to make navigation even easier.
Covering preventive, non-invasive, and natural treatments, Textbook of Natural Medicine, 4th Edition offers more than just alternative medicine. It promotes an integrated practice that can utilize natural medicine, traditional Western medicine, or a combination of both in a comprehensive, scientific treatment plan. Based on a combination of philosophy and clinical studies, Textbook of Natural Medicine helps you provide health care that identifies and controls the underlying causes of disease, is supportive of the body's own healing processes, and is considerate of each patient's unique biochemistry. Internationally known authors Joseph Pizzorno and Michael Murray include detailed pharmacologic information on herbs and supplements, plus evidence-based coverage of diseases and conditions to help you make accurate diagnoses and provide effective therapy. Comprehensive, unique coverage makes this book the gold standard in natural medicine. A scientific presentation includes the science behind concepts and treatments, and discusses Western medical treatments and how they can work with natural medicine in a comprehensive treatment plan; if natural medicine is not effective, this book recommends the Western treatment. Coverage of pharmacology of natural medicines includes the uses and potential dangers of nearly 80 herbal medicines, special nutrients, and other natural agents, addressing topics such as general information, chemical composition, history, pharmacology, clinical applications dosage, and toxicology. In-depth, evidence-based coverage of 73 diseases and conditions includes key diagnostic criteria, pathophysiology of diseases, and therapeutic rationales. Coverage of potential interactions between drugs, herbs, and supplements ensures the safest possible use for each of 79 herbs and supplements. Diagnostic procedures include practical, easy-to-follow descriptions of evidence-based techniques plus discussions of clinical application of diet analysis, food allergy testing, immune function assessment, fatty acid profiling, hair mineral analysis, and other diagnostic approaches. Common therapeutic modalities are described and reviewed, including botanical medicine, nutritional therapy, therapeutic fasting, exercise therapy, hydrotherapy, counseling, acupuncture, homeopathy, and soft tissue manipulation. Coverage of syndromes and therapies helps in understanding the underlying causes of diseases by discussing topics such as food reactions, functional toxicology, sports nutrition, stress management, and breathing pattern disorders. Coverage of the philosophy of natural medicine includes its history and background, with discussions of toxicity, detoxification, and scientific documentation of the healing actions of nature and natural substances. Internationally known authors Joseph Pizzorno and Michael Murray and more than 90 expert contributors provide material that is up to date, accurate, and informed. More than 10,000 research literature citations show that the content is based on science rather than opinions or anecdotes. 13 useful appendices offer quick lookup of frequently used charts, handouts, and information. New chapters are included on hot topics such as female infertility, medicinal mushrooms, natural products and quality control, pregnancy health and primary prevention, and Vitamin K; new appendices include a supplier certification questionnaire and cervical escharotics treatment. Thorough updates ensure that you use only the most current research and provide the most effective treatment of patients. Tabs in Specific Health Problems section separate more than 70 alphabetized diseases/conditions. One convenient volume replaces the cumbersome two-volume set for easy, convenient reference. Electronic access is available via Pageburst, making it easy to search topics, drugs, herbs and supplements, and diseases and conditions. Sold separately.
The Second Edition of Advanced Issues in Partial Least Squares Structural Equation Modeling offers a straightforward and practical guide to PLS-SEM for users ready to go further than the basics of A Primer on Partial Least Squares Structural Equation Modeling, Third Edition. Even in this advanced guide, the authors have limited the emphasis on equations, formulas, and Greek symbols, and instead rely on detailed explanations of the fundamentals of PLS-SEM and provide general guidelines for understanding and evaluating the results of applying the method. A single study on corporate reputation features as an example throughout the book, along with a single software package (SmartPLS 4.0) to provide a seamless learning experience. The approach of this book is based on the authors’ many years of conducting research and teaching methodology courses, including developing the SmartPLS software. The preparation of the book, especially this new edition, is based on the authors’ desire to communicate the PLS-SEM method to a much broader audience from management and marketing to engineering, geography, medicine, political and environmental sciences, psychology, and beyond. The Second Edition includes a new chapter on the necessary condition analysis (NCA) and covers the most recent developments in PLS-SEM, with detailed guidelines for estimating and validating higher-order constructs and nonlinear effects as well as more insights on multigroup and latent class analyses using FIMIX-PLS and PLS-POS. The book is aimed at researchers and practitioners who seek to gain comprehensive knowledge of more advanced PLS-SEM methods.
Society in Focus: An Introduction to Sociology, Ninth Edition,emphasizes how society and socialforces affect everything from globalizationand international policies to day-to-dayactivities in our personal lives. In thisedition, the authors go beyond the merequestioning of issues to take a closer lookat the social world in which we live. Theyprovide an integrated approach that usessociological thinking to help studentsanalyze and understand key concepts. Tofocus increased attention on sociologicalthinking and research methods, theyhave chosen four key themes: media andtechnology, globalization, cultural diversity,and trends for the future. Because sociologyis about all of us and our daily lives, it is aneminently practical and useful discipline forunderstanding our social world. This Ninth Edition Includes: • specific student outcomes for each chapter as well as assessment items linked to those outcomes • new chapter-opening vignettes that give real-life examples illustrating important terms, concepts, and theories included in that chapter • updated data, statistics, maps, charts, boxes, and tables citing the latest research available • examples of the powerful impact of media and technology on society, especially the role social media play in helping to shape and define our daily social lives • new photos and cartoons accompanied by critical-thinking questions that reinforce and illustrate important sociological terms, concepts, and theories
After more than 75 years, Nelson Textbook of Pediatrics remains your indispensable source for definitive, state-of-the-art answers on every aspect of pediatric care. Embracing the new advances in science as well as the time-honored art of pediatric practice, this classic reference provides the essential information that practitioners and other care providers involved in pediatric health care throughout the world need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Brand-new chapters and comprehensive revisions throughout ensure that you have the most recent information on diagnosis and treatment of pediatric diseases based on the latest recommendations and methodologies. "The coverage of such a wide range of subjects relating to child health makes this textbook still the gold standard and companion for all pediatricians across the world." Reviewed by Neel Kamal, Sept 2015 "All in all, this is an excellent and detailed paediatric review textbook which represents excellent value for money..truly a textbook for the global community" Reviewed by glycosmedia.com, Sept 2015 Form a definitive diagnosis and create the best treatment plans possible using evidence-based medicine and astute clinical experiences from leading international authors-many new to this edition. A NEW two-volume layout provides superior portability and exceptional ease of use. Gain a more complete perspective. Along with a broader emphasis on imaging and molecular diagnoses and updated references, the new edition includes an increased focus on international issues to ensure relevance in pediatrics practice throughout the world. Effectively apply the latest techniques and approaches with complete updates throughout 35 new chapters, including: Innovations in Addressing Child Health and Survival in Low Income Settings; Developmental Domains and Theories of Cognition; The Reggio Emilia Educational Approach Catatonia ; Refeeding Syndrome; Altitude-associated Illness; Genetic Approaches to Rare and Undiagnosed Diseases; Healthcare?Associated Infections; Intrapartum and Peripartum Infections; Bath salts and other drugs of abuse; Small Fiber Polyneuropathy; Microbiome; Kingella kingae; Mitochondrial Neurogastrointestinal Encephalomyopathy; Nonalcoholic Fatty Liver Disease; Plagiocephaly; CNS Vasculitis; Anterior Cruciate Ligament Rupture; and Sports-Related Traumatic Brain Injury. Recognize, diagnose, and manage genetic and acquired conditions more effectively. A new Rehabilitation section with 10 new chapters, including: Evaluation of the Child for Rehabilitative Services; Severe Traumatic Brain Injury; Spinal Cord Injury and Autonomic Crisis Management; Spasticity; Birth Brachial Plexus Palsy; Traumatic and Sports-Related Injuries; Meningomyelocele; Health and Wellness for Children with Disabilities. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Understand the principles of therapy and which drugs and dosages to prescribe for every disease. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
So far as the laws of mathematics refer to reality, they are not certain. And so far as they are certain, they do not refer to reality. -A. Einstein The word "instability" in day-to-day language is associated with some thing going wrong or being abnormal: exponential growth of cancer cells, irrational behavior of a patient, collapse of a structure, etc. This book, however, is about "good" instabilities, which lead to change, evolution, progress, creativity, and intelligence; they explain the paradox of irreversi bility in thermodynamics, the phenomena of chaos and turbulence in clas sical mechanics, and non-deterministic (multi-choice) behavior in biological and social systems. The concept of instability is an attribute of dynamical models that de scribe change in time of physical parameters, biological or social events, etc. Each dynamical model has a certain sensitivity to small changes or "errors" in initial values of its variables. These errors may grow in time, and if such growth is of an exponential rate, the behavior of the variable is defined as unstable. However, the overall effect of an unstable variable upon the dynamical system is not necessarily destructive. Indeed, there al ways exists such a group of variables that do not contribute to the energy of the system. In mechanics such variables are called ignorable or cyclic.
Comprehensive, easy to read, and clinically relevant, Bradley’s Neurology in Clinical Practice provides the most up-to-date information presented by a veritable "Who's Who" of clinical neuroscience. Its unique organization allows users to access content both by presenting symptom/sign and by specific disease entities—mirroring the way neurologists practice. A practical, straightforward style; templated organization; evidence-based references; and robust interactive content combine to make this an ideal, dynamic resource for both practicing neurologists and trainees. Authoritative, up-to-date guidance from Drs. Daroff, Jankovic, Mazziotta, and Pomeroy along with more than 150 expert contributors equips you to effectively diagnose and manage the full range of neurological disorders. Easy searches through an intuitive organization by both symptom and grouping of diseases mirrors the way you practice. The latest advances in clinical neurogenetics, brain perfusion techniques for cerebrovascular disease, the relationship between neurotrauma and neurodegenerative disease, management strategies for levodopa-related complications in movement disorders, progressive neuropsychiatric disorders arising from autoimmune encephalitis, and more keep you at the forefront of your field. Reorganized table of contents which includes new chapters on: Brain Death, Vegetative, and Minimally Conscious States; Deep Brain Stimulation; Sexual Dysfunction in Degenerative and Spinal Cord Disorders; Sports and Performance Concussion; Effects of Drug Abuse on the Nervous System; and Mechanisms of Neurodegenerative Disorders. Regular online updates reflect the latest information on the diagnosis and treatment of neurologic diseases based on the latest recommendations and methodologies. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
The third edition of this established classic text reference builds upon the strengths of its very popular predecessors. Organized as a broadly useful textbook Principles of Fluorescence Spectroscopy, 3rd edition maintains its emphasis on basics, while updating the examples to include recent results from the scientific literature. The third edition includes new chapters on single molecule detection, fluorescence correlation spectroscopy, novel probes and radiative decay engineering. Includes a link to Springer Extras to download files reproducing all book artwork, for easy use in lecture slides. This is an essential volume for students, researchers, and industry professionals in biophysics, biochemistry, biotechnology, bioengineering, biology and medicine.
This book focuses on all aspects of projection and identification, and addresses the problems and perplexities of projective identification. It is based on the First Conference of the Sigmund Freud Center of the Hebrew University of Jerusalem.
The question of why New Yorkers were such reluctant revolutionaries has long bedeviled historians. In an innovative study of New York City between 1763 and 1776, Joseph S. Tiedemann explains how conscientiously residents labored to build a consensus under difficult circumstances. New Yorkers acted the way they did not because they were mostly loyalist or because a few patrician conservatives were able to stem the tide of revolution but because the population of their city was so heterogeneous that consensus was not easily achieved.Differences within the city's pluralistic population slowed the process of hammering out a course of action acceptable to the large majority. The consensus that finally emerged had to be cautious rather than militant in order to unite as many people as possible behind the revolutionary banner. Ultimately, the time it took was far less significant, Tiedemann notes, than the fact that New York proceeded to declare independence, and went on to become a pivotal state in the new nation. In framing his argument, Tiedemann explains the limitations of interpretations offered by both progressive, New Left, and consensus historians. Citing the work of scholars as diverse as Walter Laqueur, Theda Skocpol, and Louis Kreisberg, Tiedemann pays close attention to the dynamics of British colonial rule and its impact on New York.
Modern individuals often enter analysis because of a feeling of hollowness; a deadened absence of aliveness, meaninglessness, and a sense of being alone in a world that seems otherwise exciting, engaging and alive. Joseph Newirth believes that these feelings reflect a disease of modern man which can be traced to a failure in the development of subjectivity. Through a careful reading of theory and well-reasoned presentations of case material, Newirth vividly evokes the contemporary dilemma of the individual’s lack of subjectivity. Newirth positions this lack of subjectivity as a failure in the development of the unconscious, an understanding that provides the foundation for the development of a two-person theory of the unconscious. Newirth proposes a Neo-Kleinian model of the unconscious, the “generative unconscious” in contrast to the “repressed unconscious” of classical theory, or the “relational unconscious” of interpersonal and relational theory. He defines the “generative unconscious” as a source of creativity, of apprehending and generating experience in terms of emotional meanings through the development of metaphors, transitional experiences and poetic images. Newirth draws on a wealth of clinical material to support his argument that traditional forms of interpretation are considerably less effective in the development of subjectivity than his alternative Neo-Kleinian approach. He contends that locating subjectivity in the unconscious frees us from the nineteenth century bias which privileged consciousness and rational thought, and suggests that the analytic enterprise is not to make the unconscious conscious, but rather to make the conscious unconscious.
The 5th edition of this indispensable resource captures the latest insights in neonatal neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has completely revised his masterwork from cover to cover, describing everything from the most up-to-the-minute discoveries in genetics through the latest advances in the diagnosis and management of neurologic disorders. He delivers all the clinical guidance you need to provide today's most effective care for neonates with neurological conditions. Provides comprehensive coverage of neonatal neurology, solely written by the field’s founding expert, Dr. Joseph Volpe - for a masterful, cohesive source of answers to any question that arises in your practice. Focuses on clinical evaluation and management, while also examining the many scientific and technological advances that are revolutionizing neonatal neurology. Organizes disease-focused chapters by affected body region for ease of reference. Offers comprehensive updates from cover to cover to reflect all of the latest scientific and clinical knowledge, from our most current understanding of the genetic underpinnings of neurologic disease, through the most recent neuroimaging advances . . . state-of-the-art guidelines for evaluation, diagnosis, and prognosis . . . and the newest management approaches for every type of neonatal neuropathology. Features a wealth of new, high-quality images that capture the many advances in neonatal neuroimaging, including numerous MR images.
Maurice Merleau-Ponty is the giant phenomenologist of his time in the entire French-speaking world. He is not an epistemologist nor a moralist. For him, the beginning of the beginning is human flesh; the flesh becomes word, the word becomes flesh, and both die. There is science, and there is experience/perception. The mother is the latter. They aren't contradictory, but complete and depend on each other. With regard to language, for him, there are words, and there is grammar. A word is never empty, but carries its own weight; even a lie is full of meaning. Liberty resides in grammar, an individual function and independent from books. It's in the grammar where singularity lives. Thinking and talking are the same. Wherever there is human life, there is meaning, and that is irrespective of age, culture, religion, education or social position. Merleau-Ponty is not a Marxist nor a communist. According to him, history is blind; it has no mind. He also finds a flaw in Freudianism. Flesh is an infinite universe full of stars and black holes. Following Merleau-Ponty, verity is devoiler, and devoiler is verity, but verity is never absolute. One must take a step back. There is light and there is shadow; they never coincide in human life. The shadow is always first, and no matter how one tries to run, he will never catch his shadow.
The authors show how their ego-psychological object relations theory integrates drive theory and object relations theory and does justice to recent findings regarding the vicissitudes of transference and countertransference interactions in the psychoanalytic situation. 'A significant shift has taken place in the last few decades in the way in which psychoanalytic theory has developed and in its application to psychoanalytic technique. This development has, in essence, consisted in the ascendance of object relations theory as an overall integrating frame of reference linking psychoanalytic metapsychology closer to the vicissitudes of the psychoanalytic process. This has facilitated the formulation of unconscious intrapsychic conflict in more clinically helpful ways than has the traditional frame of reference exclusively based on the conflict between drives and defensive operations. 'The great interest of the Sandler's approach resides in their careful and systematic elaboration of what might be called the various "building blocks" of a contemporary ego psychological object relations theory, carefully exploring each areas on its own merits before gradually taking them into an overall theoretical approach.
Despite the lack of guidance available for practitioners, extensive polypharmacy has become the primary method of treating patients with severe and chronic mood, anxiety, psychotic or behavioral disorders. This ground-breaking new book provides an overview of psychopharmacology knowledge and decision-making strategies, integrating findings from evidence-based trials with real-world clinical presentations. It adopts the approach and mind-set of a clinical investigator and reveals how prescribers can practice 'bespoke psychopharmacology', tailoring care to the individualized needs of patients. Practitioners at all levels of expertise will enhance their ability to devise rationale-based treatments, targeting manifestations of dysfunctional neural circuitry and dimensions of psychopathology that cut across conventional psychiatric diagnoses. Presented in a user-friendly, practical, full-colour layout and incorporating summary tables, bullet points, and illustrative case vignettes, it is an invaluable guide for all healthcare professionals prescribing psychotropic medications, including psychiatry specialists, primary care physicians, and advanced practice registered nurses.
A practical, dynamic resource for practicing neurologists, clinicians and trainees, Bradley and Daroff's Neurology in Clinical Practice, Eighth Edition, offers a straightforward style, evidence-based information, and robust interactive content supplemented by treatment algorithms and images to keep you up to date with all that's current in this fast-changing field. This two-volume set is ideal for daily reference, featuring a unique organization by presenting symptom/sign and by specific disease entities—allowing you to access content in ways that mirror how you practice. More than 150 expert contributors, led by Drs. Joseph Jankovic, John C. Mazziotta, Scott L. Pomeroy, and Nancy J. Newman, provide up-to-date guidance that equips you to effectively diagnose and manage the full range of neurological disorders. - Covers all aspects of today's neurology in an easy-to-read, clinically relevant manner. - Allows for easy searches through an intuitive organization by both symptom and grouping of diseases. - Features new and expanded content on movement disorders, genetic and immunologic disorders, tropical neurology, neuro-ophthalmology and neuro-otology, palliative care, pediatric neurology, and new and emerging therapies. - Offers even more detailed videos that depict how neurological disorders manifest, including EEG and seizures, deep brain stimulation for PD and tremor, sleep disorders, movement disorders, ocular oscillations, EMG evaluation, cranial neuropathies, and disorders of upper and lower motor neurons, as well as other neurologic signs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
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