Adalia Lisbet has made a name for herself as a duelist after being forced from her home over ten years ago. She has even reached the title of Bladedancer, showing her mastery in the art of swordplay. But when her father, the man who banished her, calls her back to his house she is confronted with trials no sword can cut. Back among a family she thought she would never see again, Adalia risks collapsing beneath the weight of memory. But alongside a history of grief are also moments of triumph. She has traveled across the land, testing herself against foes both mundane and fantastic. Will despair drag Adalia under, or will she rise above to grasp the possibility of hope?
A “how to” guide for applying statistical methods to biomarker data analysis Presenting a solid foundation for the statistical methods that are used to analyze biomarker data, Analysis of Biomarker Data: A Practical Guide features preferred techniques for biomarker validation. The authors provide descriptions of select elementary statistical methods that are traditionally used to analyze biomarker data with a focus on the proper application of each method, including necessary assumptions, software recommendations, and proper interpretation of computer output. In addition, the book discusses frequently encountered challenges in analyzing biomarker data and how to deal with them, methods for the quality assessment of biomarkers, and biomarker study designs. Covering a broad range of statistical methods that have been used to analyze biomarker data in published research studies, Analysis of Biomarker Data: A Practical Guide also features: A greater emphasis on the application of methods as opposed to the underlying statistical and mathematical theory The use of SAS®, R, and other software throughout to illustrate the presented calculations for each example Numerous exercises based on real-world data as well as solutions to the problems to aid in reader comprehension The principles of good research study design and the methods for assessing the quality of a newly proposed biomarker A companion website that includes a software appendix with multiple types of software and complete data sets from the book’s examples Analysis of Biomarker Data: A Practical Guide is an ideal upper-undergraduate and graduate-level textbook for courses in the biological or environmental sciences. An excellent reference for statisticians who routinely analyze and interpret biomarker data, the book is also useful for researchers who wish to perform their own analyses of biomarker data, such as toxicologists, pharmacologists, epidemiologists, environmental and clinical laboratory scientists, and other professionals in the health and environmental sciences.
The latest scholarly developments in research on banking, financial markets, and the recent financial crisis. This selection of papers were presented at the Wolpertinger Conference held in Valletta, Malta, 2012 and provide insights into bank performance, banking risk, securitisation, bank stability, sovereign debt and derivatives.
A woman diagnosed with schizophrenia has been tortured by visions her entire life. Now, completely unhinged, she is determined to find out why by following her hallucinations down a deadly and terrifying path.
Synopsis of The Aventi Ciphers Is it just a coincidence that prominent men and women are dying from brain-related episodes, or has a killer learned of a new scientific method of high-tech serial murder? A complicated code, an algorithm cipher holding the solution, has been secretly installed on the laptop computer of New York’s leading forensic investigator, Jack Reynolds. Along with his pal, rogue private eye Danny Lorenzo, Jack becomes deeply involved with elements of the CIA and the FBI. The hunt for a crack Middle Eastern agent leads them from Halifax to Key West and to the puzzle’s answer, while exposing an assassination conspiracy of awesome proportions and a new energy technology that will change the world for a hundred years. In this fast-paced tale of intrigue, the reader is kept on the edge as the story unfolds to a surprising conclusion, and author Joseph Clinard delivers his third Jack Reynolds novel, once again in gripping form.
Harry Dean Stanton (1926–2017) got his start in Hollywood in TV productions such as Zane Grey Theater and Gunsmoke. After a series of minor parts in forgettable westerns, he gradually began to get film roles that showcased his laid-back acting style, appearing in Cool Hand Luke (1967), Kelly's Heroes (1970), The Godfather: Part II (1974), and Alien (1979). He became a headliner in the eighties—starring in Wim Wenders's moving Paris, Texas (1984) and Alex Cox's Repo Man (1984)—but it was his extraordinary skill as a character actor that established him as a revered cult figure and kept him in demand throughout his career. Joseph B. Atkins unwinds Stanton's enigmatic persona in the first biography of the man Vanity Fair memorialized as "the philosopher poet of character acting." He sheds light on Stanton's early life in West Irvine, Kentucky, exploring his difficult relationship with his Baptist parents, his service in the Navy, and the events that inspired him to drop out of college and pursue acting. Atkins also chronicles Stanton's early years in California, describing how he honed his craft at the renowned Pasadena Playhouse before breaking into television and movies. In addition to examining the actor's acclaimed body of work, Atkins also explores Harry Dean Stanton as a Hollywood legend, following his years rooming with Jack Nicholson, partying with David Crosby and Mama Cass, jogging with Bob Dylan, and playing poker with John Huston. "HD Stanton" was scratched onto the wall of a jail cell in Easy Rider (1969) and painted on an exterior concrete wall in Drive, He Said (1971). Critic Roger Ebert so admired the actor that he suggested the "Stanton-Walsh Rule," which states that "no movie featuring either Harry Dean Stanton or M. Emmet Walsh in a supporting role can be altogether bad." Harry Dean Stanton is often remembered for his crowd-pleasing roles in movies like Pretty in Pink (1986) or Escape from New York (1981), but this impassioned biography illuminates the entirety of his incredible sixty-year career. Drawing on interviews with the actor's friends, family, and colleagues, this much-needed book offers an unprecedented look at a beloved figure.
Discusses the fundamental principles of the design and development of microwave satellite switches utilized in military, commercial, space, and terrestrial communication This book deals with important RF/microwave components such as switches and phase shifters, which are relevant to many RF/microwave applications. It provides the reader with fundamental principles of the operation of some basic ferrite control devices and explains their system uses. This in-depth exploration begins by reviewing traditional nonreciprocal components, such as circulators, and then proceeds to discuss the most recent advances. This sequential approach connects theoretical and scientific characteristics of the devices listed in the title with practical understanding and implementation in the real world. Microwave Polarizers, Power Dividers, Phase Shifters, Circulators and Switches covers the full scope of the subject matter and serves as both an educational text and resource for practitioners. Among the many topics discussed are microwave switching, circular polarization, planar wye and equilateral triangle resonators, and many others. Translates concepts and ideas fundamental to scientific knowledge into a more visual description Describes a wide array of devices including waveguides, shifters, and circulators Covers the use of finite element algorithms in design Microwave Polarizers, Power Dividers, Phase Shifters, Circulators and Switches is an ideal reference for all practitioners and graduate students involved in this niche field.
The Bellagio Group was founded at a time of global economic crisis. This collection brings together the private correspondence and published papers of the Group’s founders, creating a picture of the personalities, issues, debates and compromises leading to the adoption of flexible exchange rates and a modified Triffin plan.
This study of "The Stern Gang" attempts to demythologize the image of this extremist, Zionist underground group. The book analyzes the party's split from the Irgun Zvai Leumi (National Military Organization) and its attempts to synthesize the politics and ideals of the right and left.
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical issues of PRO measures. The book discusses key concepts relating to the measurement, implementation, and interpretation of PRO measures. It covers both introductory and advanced psychometric and biostatistical methods for constructing and analyzing PRO measures. The authors include many relevant real-life applications based on their extensive first-hand experiences in the pharmaceutical industry. They implement a wealth of simulated datasets to illustrate concepts and heighten understanding based on practical scenarios. For readers interested in conducting statistical analyses of PRO measures and delving more deeply into the analytic details, most chapters contain SAS code and output that illustrate the methodology. Along with providing numerous references, the book highlights current regulatory guidelines.
The principles of value investing have resonated with savvy practitioners in the world of finance for a long time. In Creating Strategic Value, Joseph Calandro Jr. explores how the core ideas and methods of value investing can be profitably applied to corporate strategy and management. Calandro builds from an analysis of traditional value investing concepts to their strategic applications. He surveys value investing’s past, present, and future, drawing on influential texts, from Graham and Dodd’s time-tested works to more recent studies, to reveal potent managerial lessons. He explains the theoretical aspects of value investing-consistent approaches to corporate strategy and management and details how they can be successfully employed through practical case studies that demonstrate value realization in action. Calandro analyzes the applicability of key ideas such as the margin-of-safety principle to corporate strategy in a wide range of areas beyond stocks and bonds. He highlights the importance of an “information advantage”—knowing something that a firm’s competitors either do not know or choose to ignore—and explains how corporate managers can apply this key value investing differentiator. Offering expert insight into the use of time-tested value investing principles in new fields, Creating Strategic Value is an important book for corporate strategy and management practitioners at all levels as well as for students and researchers.
This revolutionary, user-friendly textbook not only guides social workers in developing competence in the DSM system of diagnosis, it also assists them in staying attuned during client assessment to social work values and principles: a focus on client strengths, concern for the worth and dignity of individuals, appreciation of environmental influences on behavior, and commitment to evidence-informed practice. The authors, seasoned practitioner-scholars, provide an in-depth exploration of fourteen major mental disorders that social workers commonly see in practice, including anxiety disorders, depression, bipolar disorder, and schizophrenia. They skillfully integrate several perspectives in order to help practitioners meet the challenges they will face in client assessment. A risk and resilience framework helps social workers understand environmental influences on the emergence of mental disorders and the strengths that clients already possess. Social workers will also learn to apply critical thinking to the DSM when it is inconsistent with social work values and principles. Finally, the authors catalog the latest evidence-based assessment instruments and treatments for each disorder so that social workers can intervene efficiently and effectively, using the best resources available. Students and practitioners alike will appreciate the wealth of case examples, evidence-based assessment instruments, treatment plans, and new social diversity sections that make this an essential guide to the assessment and diagnostic processes in social work practice.
Nelson Textbook of Pediatrics has been the world’s most trusted pediatrics resource for nearly 75 years. Drs. Robert Kliegman, Bonita Stanton, Richard Behrman, and two new editors—Drs. Joseph St. Geme and Nina Schor—continue to provide the most authoritative coverage of the best approaches to care. This streamlined new edition covers the latest on genetics, neurology, infectious disease, melamine poisoning, sexual identity and adolescent homosexuality, psychosis associated with epilepsy, and more. Understand the principles of therapy and which drugs and dosages to prescribe for every disease. Locate key content easily and identify clinical conditions quickly thanks to a full-color design and full-color photographs. Access the fully searchable text online at www.expertconsult.com, along with abundant case studies, new references and journal articles, Clinics articles, and exclusive web-only content. Stay current on recent developments and hot topics such as melamine poisoning, long-term mechanical ventilation in the acutely ill child, sexual identity and adolescent homosexuality, age-specific behavior disturbances, and psychosis associated with epilepsy. Tap into substantially enhanced content with world-leading clinical and research expertise from two new editors—Joseph St. Geme, III, MD and Nina Schor, MD—who contribute on the key subspecialties, including pediatric infectious disease and pediatric neurology. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Recognize, diagnose, and manage genetic conditions more effectively using an expanded section that covers these diseases, disorders, and syndromes extensively. Find information on chronic and common dermatologic problems more easily with a more intuitive reorganization of the section.
The definitive bible for the field of biomedical engineering, this collection of volumes is a major reference for all practicing biomedical engineers and students. Now in its fourth edition, this work presents a substantial revision, with all sections updated to offer the latest research findings. New sections address drugs and devices, personalized medicine, and stem cell engineering. Also included is a historical overview as well as a special section on medical ethics. This set provides complete coverage of biomedical engineering fundamentals, medical devices and systems, computer applications in medicine, and molecular engineering.
Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine. More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.
Statistical Design, Monitoring, and Analysis of Clinical Trials, Second Edition concentrates on the biostatistics component of clinical trials. This new edition is updated throughout and includes five new chapters. Developed from the authors’ courses taught to public health and medical students, residents, and fellows during the past 20 years, the text shows how biostatistics in clinical trials is an integration of many fundamental scientific principles and statistical methods. The book begins with ethical and safety principles, core trial design concepts, the principles and methods of sample size and power calculation, and analysis of covariance and stratified analysis. It then focuses on sequential designs and methods for two-stage Phase II cancer trials to Phase III group sequential trials, covering monitoring safety, futility, and efficacy. The authors also discuss the development of sample size reestimation and adaptive group sequential procedures, phase 2/3 seamless design and trials with predictive biomarkers, exploit multiple testing procedures, and explain the concept of estimand, intercurrent events, and different missing data processes, and describe how to analyze incomplete data by proper multiple imputations. This text reflects the academic research, commercial development, and public health aspects of clinical trials. It gives students and practitioners a multidisciplinary understanding of the concepts and techniques involved in designing, monitoring, and analyzing various types of trials. The book’s balanced set of homework assignments and in-class exercises are appropriate for students and researchers in (bio)statistics, epidemiology, medicine, pharmacy, and public health.
The author of "Digger" and "The Concrete Inquisition" presents this thriller featuring an ex-cop who solved the murder of the president's first husband and brought the killers to justice, and who himself becomes the first private eye to live in the White House.
A fresh look at a “robot-proof” education in the new age of generative AI. In 2017, Robot-Proof, the first edition, foresaw the advent of the AI economy and called for a new model of higher education designed to help human beings flourish alongside smart machines. That economy has arrived. Creative tasks that, seven years ago, seemed resistant to automation can now be performed with a simple prompt. As a result, we must now learn not only to be conversant with these technologies, but also to comprehend and deploy their outputs. In this revised and updated edition, Joseph Aoun rethinks the university’s mission for a world transformed by AI, advocating for the lifelong endeavor of a “robot-proof” education. Aoun puts forth a framework for a new curriculum, humanics, which integrates technological, data, and human literacies in an experiential setting, and he renews the call for universities to embrace lifelong learning through a social compact with government, employers, and learners themselves. Drawing on the latest developments and debates around generative AI, Robot-Proof is a blueprint for the university as a force for human reinvention in an era of technological change—an era in which we must constantly renegotiate the shifting boundaries between artificial intelligence and the capacities that remain uniquely human.
Most film critics point to classic conflicts—good versus evil, right versus wrong, civilization versus savagery—as defining themes of the American Western. In this provocative examination of Westerns from Tumbleweeds (1925) to Rango (2011), Robin L. Murray and Joseph K. Heumann argue for a more expansive view that moves beyond traditional conflicts to encompass environmental themes and struggles. The environment, after all, is the fundamental stage for most western stories, from land rush dramas that pit “sod busters” against ranchers to conflicts between mining-town communities and corporations. Because environmental issues lie at the forefront of so many conflicts today, Murray and Heumann believe that the Western is ripe for such new examination. Drawing on perspectives from both film studies and environmental history, the authors show how western films frequently deal with issues related to land use and different ways of looking at the natural world. In films as diverse as Gene Autry musicals, early John Wayne B-Westerns, and revisionist critiques such as the 2010 remake of True Grit, resources are exploited in the name of progress. Beginning with an analysis of two iconic Westerns, Shane and The Searchers, Murray and Heumann identify the environmental dichotomies—previously overlooked by critics—that are broached in both films, and they clarify the history that lies behind the environmental debates in these films and many others. How do Westerns respond to the historical contexts they present? And what do those responses suggest about American views of nature and its exploitation? The conflicts these movies address grow out of differing views of progress, frequently in relation to technology. The authors show that such binary oppositions tend to blur when examined closely, demonstrating that environmental issues are often more complex than we realize.
A modern pedagogical treatment of the latest industry trends in rocket propulsion, developed from the authors' extensive experience in both industry and academia. Students are guided along a step-by-step journey through modern rocket propulsion, beginning with the historical context and an introduction to top-level performance measures, and progressing on to in-depth discussions of the chemical aspects of fluid flow combustion thermochemistry and chemical equilibrium, solid, liquid, and hybrid rocket propellants, mission requirements, and an overview of electric propulsion. With a wealth of homework problems (and a solutions manual for instructors online), real-life case studies and examples throughout, and an appendix detailing key numerical methods and links to additional online resources, this is a must-have guide for senior and first year graduate students looking to gain a thorough understanding of the topic along with practical tools that can be applied in industry.
This book presents the methodology and applications of Data Envelopment Analysis (DEA) in measuring productivity, efficiency and effectiveness in Financial Services firms such as banks, bank branches, stock markets, pension funds, mutual funds, insurance firms, credit unions, risk tolerance, and corporate failure prediction. Financial service DEA research includes banking; insurance businesses; hedge, pension and mutual funds; and credit unions. Significant business transactions among financial service organizations such as bank mergers and acquisitions and valuation of IPOs have also been the focus of DEA research. The book looks at the range of DEA uses for financial services by presenting prior studies, examining the current capabilities reflected in the most recent research, and projecting future new uses of DEA in finance related applications.
In Pueblos, Plains, and Province Joseph P. Sánchez offers an in-depth examination of sociopolitical conflict in seventeenth-century New Mexico, detailing the effects of Spanish colonial policies on settlers’, missionaries’, and Indigenous peoples’ struggle for economic and cultural control of the region. Sánchez explores the rich archival documentation that provides cultural, linguistic, and legal views of the values of the period. Spanish dual Indian policies for Pueblo and Plains tribes challenged Indigenous political and social systems to conform to the imperial structure for pacification purposes. Meanwhile, missionary efforts to supplant Indigenous religious beliefs with a Christian worldview resulted, in part, in a syncretism of the two worlds. Indigenous resentment of these policies reflected the contentious disagreements between Spanish clergymen and civil authorities, who feuded over Indigenous labor, and encroachment on tribal sovereignties with demands for sworn loyalty to Spanish governance. The little-studied “starvation period” adversely affected Spanish-Pueblo relationships for the remainder of the century and contributed significantly to the battle at Acoma, the Jumano War, and the Pueblo Revolt of 1680. Pueblos, Plains, and Province shows how history, culture, and tradition in New Mexico shaped the heritage shared by Spain, Mexico, the United States, and Native American tribes and will be of interest to scholars and students of Indigenous, colonial, and borderlands history.
Designed to address all aspects of shoulder reconstruction, this volume in the Disorders of the Shoulder series provides complete and practical discussions of the reconstructive process—from diagnosis and planning, through surgical and nonsurgical treatments, to outcome and return to functionality.
Understanding and developing expertise is an important concern for any researcher or practitioner working in elite or high performance sport. Whether it's identifying talented young athletes or developing methods for integrating cutting-edge sport science into daily coaching practice, scientists, coaches and researchers all need to understand the skills, characteristics, and knowledge that distinguish the expert performer in sport. The Routledge Handbook of Sport Expertise is the first book to offer a comprehensive overview of current research and practice in the emerging field of sports expertise. Adopting a multi-disciplinary, multi-faceted approach, the book offers in-depth discussion of methodological and philosophical issues in sport expertise, as well as the characteristics that describe sporting ‘experts’ and how they can be facilitated and developed. Exploring research, theory and practice, the book also examines how scientists and practitioners can work together to improve the delivery of applied sport science. With contributions from many of the world’s leading researchers in expertise and skill acquisition in sport, the Routledge Handbook of Sport Expertise is important reading for any advanced student, researcher, coach or sport science support officer looking to better understand this cutting-edge topic.
The emphasis on change at many levels of organization is critically important as is the first attempt to integrate sophisticated theory and research in organization psychology (e.g., Gersick, Hackman) with social psychological models of development such as Moreland and Levine." --Reuben M. Baron, Emeritus, University of Connecticut "Arrow, McGrath, and Berdahl′s ′Small Groups as Complex Systems′ will change the way you think about groups, the way you think about research, and even the way you think about science." --Donelson R. Forsyth, Psychology, Virginia Commonwealth U "The book is excellent, one of those very rare works that will have substantial impact on the field. I would use the book without hesitation in any advanced graduate seminar dealing with groups." --Donelson R. Forsyth, Psychology, Virginia Commonwealth U "A conceptually elegant analysis of groups as systems. Although the systems approach has been growing more influential in various fields of social psychology in the last ten years, no one has put forward a definitive analysis that applies with fidelity the general systems approach to group processes. McGrath and his colleagues fill that gap, not by paying lip service to popular scientific concepts such as recursive causality, open systems, attractors, and complexity theory, but by fully integrating these concepts into their no-nonsense analysis of such group level processes as formation, task performance, composition, development, and termination. Empirical work is folded into the theoretical mix along the way, but the focus is unrelentingly conceptual with the result that the authors deliver on their promise of developing a powerful, unified theory of group dynamics." --Donelson R. Forsyth, Psychology, Virginia Commonwealth U "Theirs is an ambitious book. They have profound ramifications for experimental social psychology. It is worth mentioning that AMD (Arrow, McGrarth, and Berdahl) list an ethnographic approach, which often implies the adoption of hermeneutic and semiotic methods (a hallmark of the anti-Enlightenment tradition in psychology), as a possible way forward." --Yoshihisa Kashima, American Journal of Psychology What are groups? How do they behave? Arrow, McGrath, and Berdahl answer these questions by developing a general theory of small groups as complex systems. Basing their theory on concepts distilled from general systems theory, dynamical systems theory, and complexity and chaos theory, they explore groups as adaptive, dynamic systems that are driven by interactions among group members as well as between the group and its embedding contexts. In addition, they consider not only the group′s members and their distribution of attributes, but also the group′s tasks and technology in order to understand how those members, tasks, and tools are intertwined, coordinated, and adjusted. Throughout the book, the authors focus our attention on relationships among people, tools, and tasks that are activated by a combination of individual and collective purposes and goals that change and evolve as the group interacts over time.
Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiology to material science and nanotechnology. Reflecting the enormous growth and change in biomedical engineering during the infancy of the 21st century, The Biomedical Engineering Handbook enters its third edition as a set of three carefully focused and conveniently organized books. Reviewing applications at the leading edge of modern biomedical engineering, Tissue Engineering and Artificial Organs explores transport phenomena, biomimetics systems, biotechnology, prostheses, artificial organs, and ethical issues. The book features approximately 90% new material in the tissue engineering section, integrates coverage of life sciences with a new section on molecular biology, and includes a new section on bionanotechnology. Prominent leaders from around the world share their expertise in their respective fields with many new and updated chapters. New technologies and methods spawned by biomedical engineering have the potential to improve the quality of life for everyone, and Tissue Engineering and Artificial Organs sheds light on the tools that will enable these advances.
An estimated 30,000 children are born in the USA with congenital heart disease each year, two thirds of which will require corrective surgery. Medical advances have formed a trend of operating on newborns rather than waiting until the child is older. Ten years ago, the mortality for these operationswas 60% to 70%. That percentage has dropped to 2%. This specialized book explores the basic mechanisms of neurologic injury associated with congenital heart surgery while covering the emerging technologies for assessment of neurologic integrity and injury. The text also highlights the current and future techniques for reducing and preventing these injuries, and reviews the pertinent medicolegal issues.
An uproarious and frank memoir of illness and recovery, No Laughing Matter is a story of friendship and recuperation from the author of the classic Catch-22. It all began one typical day in the life of Joe Heller. He was jogging four miles at a clip these days, working on his novel God Knows, coping with the complications of an unpleasant divorce, and pigging out once or twice a week on Chinese food with cronies like Mel Brooks, Mario Puzo, and his buddy of more than twenty years, Speed Vogel. He was feeling perfectly fine that day—but within twenty-four hours he would be in intensive care at Manhattan's Mount Sinai Hospital. He would remain hospitalized for nearly six months and leave in a wheelchair. Joseph Heller had Guillain-Barré syndrome, a debilitating, sometimes fatal condition that can leave its victims paralyzed from head to toe. The clan gathered immediately. Speed—sometime artist, sometime businessman, sometime herring taster, and now a coauthor—moved into Joe's apartment as messenger, servant, and shaman. Mel Brooks, arch-hypochondriac of the Western world, knew as much about Heller's condition as the doctors. Mario Puzo, author of the preeminent gangster novel of our time, proved to be the most reluctant man ever to be dragged along on a hospital visit. These and lots of others rallied around the sickbed in a show of loyalty and friendship that not only built a wild and spirited camaraderie but helped bring Joe Heller, writer and buddy extraordinaire, through his greatest crisis. This book is an inspiring, hilarious memoir of a calamitous illness and the rocky road to recuperation—as only the author of Catch-22 and the friend who helped him back to health could tell it. No Laughing Matter is as wacky, terrifying, and greathearted as any fiction Joseph Heller ever wrote.
A room’s acoustic character seems at once the most technical and the most mystical of concerns. Since the early Enlightenment, European architects have systematically endeavored to represent and control the propagation of sound in large interior spaces. Their work has been informed by the science of sound but has also been entangled with debates on style, visualization techniques, performance practices, and the expansion of the listening public. Echo’s Chambers explores how architectural experimentation from the seventeenth through the mid-twentieth centuries laid the groundwork for concepts of acoustic space that are widely embraced in contemporary culture. It focuses on the role of echo and reverberation in the architecture of Pierre Patte, Claude-Nicolas Ledoux, Carl Ferdinand Langhans, and Le Corbusier, as well as the influential acoustic ideas of Athanasius Kircher, Richard Wagner, and Marshall McLuhan. Drawing on interdisciplinary theories of media and auditory culture, Joseph L. Clarke reveals how architecture has impacted the ways we continue to listen to, talk about, and creatively manipulate sound in the physical environment.
Credit is essential in the modern world and creates wealth, provided it is used wisely. The Global Credit Crisis during 2008/2009 has shown that sound understanding of underlying credit risk is crucial. If credit freezes, almost every activity in the economy is affected. The best way to utilize credit and get results is to understand credit risk. Advanced Credit Risk Analysis and Management helps the reader to understand the various nuances of credit risk. It discusses various techniques to measure, analyze and manage credit risk for both lenders and borrowers. The book begins by defining what credit is and its advantages and disadvantages, the causes of credit risk, a brief historical overview of credit risk analysis and the strategic importance of credit risk in institutions that rely on claims or debtors. The book then details various techniques to study the entity level credit risks, including portfolio level credit risks. Authored by a credit expert with two decades of experience in corporate finance and corporate credit risk, the book discusses the macroeconomic, industry and financial analysis for the study of credit risk. It covers credit risk grading and explains concepts including PD, EAD and LGD. It also highlights the distinction with equity risks and touches on credit risk pricing and the importance of credit risk in Basel Accords I, II and III. The two most common credit risks, project finance credit risk and working capital credit risk, are covered in detail with illustrations. The role of diversification and credit derivatives in credit portfolio management is considered. It also reflects on how the credit crisis develops in an economy by referring to the bubble formation. The book links with the 2008/2009 credit crisis and carries out an interesting discussion on how the credit crisis may have been avoided by following the fundamentals or principles of credit risk analysis and management. The book is essential for both lenders and borrowers. Containing case studies adapted from real life examples and exercises, this important text is practical, topical and challenging. It is useful for a wide spectrum of academics and practitioners in credit risk and anyone interested in commercial and corporate credit and related products.
This book offers 58 cases that combine both the qualitative and quantitative aspects of financial management. The cases are based on real firms, real products, real individuals, and most importantly, real issues and offer a complete picture of the financial management process.
Fractures and dislocation of the shoulder are common, particularly fractures of the clavicle and dislocations of the acromioclavicular and glenohumeral joints. This detailed volume in the Disorders of the Shoulder set covers fractures and dislocations of the shoulder due to traumatic injury.
After more than 75 years, Nelson Textbook of Pediatrics remains your indispensable source for definitive, state-of-the-art answers on every aspect of pediatric care. Embracing the new advances in science as well as the time-honored art of pediatric practice, this classic reference provides the essential information that practitioners and other care providers involved in pediatric health care throughout the world need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Brand-new chapters and comprehensive revisions throughout ensure that you have the most recent information on diagnosis and treatment of pediatric diseases based on the latest recommendations and methodologies. Form a definitive diagnosis and create the best treatment plans possible using evidence-based medicine and astute clinical experiences from leading international authors—many new to this edition. A NEW layout provides superior portability and exceptional ease of use. Gain a more complete perspective. Along with a broader emphasis on imaging and molecular diagnoses and updated references, the new edition includes an increased focus on international issues to ensure relevance in pediatrics practice throughout the world. Effectively apply the latest techniques and approaches with complete updates throughout 35 new chapters, including: Innovations in Addressing Child Health and Survival in Low Income Settings; Developmental Domains and Theories of Cognition; The Reggio Emilia Educational Approach Catatonia ; Refeeding Syndrome; Altitude-associated Illness; Genetic Approaches to Rare and Undiagnosed Diseases; Healthcare−Associated Infections; Intrapartum and Peripartum Infections; Bath salts and other drugs of abuse; Small Fiber Polyneuropathy; Microbiome; Kingella kingae; Mitochondrial Neurogastrointestinal Encephalomyopathy; Nonalcoholic Fatty Liver Disease; Plagiocephaly; CNS Vasculitis; Anterior Cruciate Ligament Rupture; and Sports-Related Traumatic Brain Injury. Recognize, diagnose, and manage genetic and acquired conditions more effectively. A new Rehabilitation section with 10 new chapters, including: Evaluation of the Child for Rehabilitative Services; Severe Traumatic Brain Injury; Spinal Cord Injury and Autonomic Crisis Management; Spasticity; Birth Brachial Plexus Palsy; Traumatic and Sports-Related Injuries; Meningomyelocele; Health and Wellness for Children with Disabilities. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Understand the principles of therapy and which drugs and dosages to prescribe for every disease.
After more than 75 years, Nelson Textbook of Pediatrics remains your indispensable source for definitive, state-of-the-art answers on every aspect of pediatric care. Embracing the new advances in science as well as the time-honored art of pediatric practice, this classic reference provides the essential information that practitioners and other care providers involved in pediatric health care throughout the world need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Brand-new chapters and comprehensive revisions throughout ensure that you have the most recent information on diagnosis and treatment of pediatric diseases based on the latest recommendations and methodologies. "The coverage of such a wide range of subjects relating to child health makes this textbook still the gold standard and companion for all pediatricians across the world." Reviewed by Neel Kamal, Sept 2015 "All in all, this is an excellent and detailed paediatric review textbook which represents excellent value for money..truly a textbook for the global community" Reviewed by glycosmedia.com, Sept 2015 Form a definitive diagnosis and create the best treatment plans possible using evidence-based medicine and astute clinical experiences from leading international authors-many new to this edition. A NEW two-volume layout provides superior portability and exceptional ease of use. Gain a more complete perspective. Along with a broader emphasis on imaging and molecular diagnoses and updated references, the new edition includes an increased focus on international issues to ensure relevance in pediatrics practice throughout the world. Effectively apply the latest techniques and approaches with complete updates throughout 35 new chapters, including: Innovations in Addressing Child Health and Survival in Low Income Settings; Developmental Domains and Theories of Cognition; The Reggio Emilia Educational Approach Catatonia ; Refeeding Syndrome; Altitude-associated Illness; Genetic Approaches to Rare and Undiagnosed Diseases; Healthcare?Associated Infections; Intrapartum and Peripartum Infections; Bath salts and other drugs of abuse; Small Fiber Polyneuropathy; Microbiome; Kingella kingae; Mitochondrial Neurogastrointestinal Encephalomyopathy; Nonalcoholic Fatty Liver Disease; Plagiocephaly; CNS Vasculitis; Anterior Cruciate Ligament Rupture; and Sports-Related Traumatic Brain Injury. Recognize, diagnose, and manage genetic and acquired conditions more effectively. A new Rehabilitation section with 10 new chapters, including: Evaluation of the Child for Rehabilitative Services; Severe Traumatic Brain Injury; Spinal Cord Injury and Autonomic Crisis Management; Spasticity; Birth Brachial Plexus Palsy; Traumatic and Sports-Related Injuries; Meningomyelocele; Health and Wellness for Children with Disabilities. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Understand the principles of therapy and which drugs and dosages to prescribe for every disease. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
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