Memory reconsolidation is the process that serves to restabilize a memory that has been destabilized through memory retrieval. This retrieval-induced plasticity has been extensively studied in the hippocampus, among other neural loci. A focus on hippocampal memory reconsolidation, for contextual fear, pure contextual, and spatial memories, reveals interesting constraints on when a retrieved memory undergoes reconsolidation. Moreover, the emergence of dissociable mechanisms of hippocampal contextual fear memory consolidation and reconsolidation has allowed the demonstration that reconsolidation serves to update both the strength and the content of hippocampal memories. This provides compelling evidence that, at least in the hippocampus, reconsolidation exists in order to modify memories. However, whether or not these hippocampal findings can be generalized to nonhippocampal memories remains to be determined.
Consolidating one of the most complex and multi-faceted eras in American History, this new edition of Jonathan Wells’s A House Divided unifies the broad and varied scholarship on the American Civil War. Amassing a variety of research, this accessible and readable text introduces readers to both the war and the Reconstruction period, and how Americans lived during this time of great upheaval in the country's history. Designed for a variety of subjects and teaching styles, this text not only looks at the Civil War from a historical perspective, but also analyzes its ramifications on the United States and American identities through the present day. This second edition has been updated throughout, incorporating new scholarship from recent studies on the Civil War era, and includes additional photographs and maps (now incorporated throughout the text), updated bibliographies, and a supplementary companion website.
This impressive author team brings the wealth of advances in conservation genetics into the new edition of this introductory text, including new chapters on population genomics and genetic issues in introduced and invasive species. They continue the strong learning features for students - main points in the margin, chapter summaries, vital support with the mathematics, and further reading - and now guide the reader to software and databases. Many new references reflect the expansion of this field. With examples from mammals, birds ...
This edited volume explores the analytical possibilities of contrasting Brazil and the United Kingdom as examples of emerging and established powers, respectively. It is organised around several themes focusing on the roles of Brazil and the United Kingdom in the management of global economic governance, international development, international security, the politics of regional integration, global climate change governance, and the political leveraging of sports mega-events. Each chapter explores Brazil’s and/or the UK’s particular foreign policies and their resulting impact on these key areas of global governance and politics. The conceptual focus is on these states’ motivations as either status-seekers (Brazil) or status-maintainers (UK) in the context of a fast moving international landscape. The chapters in this book directly or indirectly indicate that these states wish to draw attention to their aspiring or established positions as key global players through either visible foreign policy action and/or symbolic rhetoric. This book was originally published as a special issue of Global Society.
Clarkson & Hill's Conflict of Laws provides a detailed account of the topics taught on private international law courses, reflecting the profound changes that the subject has undergone in recent years. Focusing on key principles in an engaging and approachable style, this text is key reading for private international law students.
This book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new technologies to help overcome the bottlenecks in developing stem cells as therapeutic agents. A key reference for professionals working in stem cell science, it presents the general principles and methodologies in stem cell research and covers topics such as derivitization and characterization of stem cells, stem cell culture and maintenance, stem cell engineering, applications of high-throughput screening, and stem cell genetic modification with their use for drug delivery.
The Common Core State Standards are at the center of the latest firestorm in American education reform. But this is not the nation’s first torrid experience with standards implementation. In Challenging Standards, Jonathan Supovitz and James Spillane bring together the collective knowledge of top education researchers who have both experienced and investigated education reform challenges in the past. Combining both evidence-based research and applied knowledge, the contributors share with educational leaders their accrued wisdom about implementing standards in classrooms and systems, building capacity through relationships, and navigating the fractious political terrain. Each section of the book contains a set of facilitative questions that will help leadership teams, book clubs, and professional learning communities connect the chapters to their work.
This spellbinding account of the most famous shipwreck before the "Titanic" draws on published accounts and journals of survivors. Historian Miles brilliantly reconstructs the ill-fated voyage and the events that inspired Theodore Gericaults painting "The Raft of the Medusa.
NATIONAL BESTSELLER • The intimate true story of three of the greatest American generals of World War II, and how their intense blend of comradery and competition spurred Allied forces to victory. “One of the great stories of the American military.”—Thomas E. Ricks, Pulitzer Prize-winning author of The Generals Dwight Eisenhower, George Patton and Omar Bradley shared bonds going back decades. All three were West Pointers who pursued their army careers with a remarkable zeal, even as their paths diverged. Bradley was a standout infantry instructor, while Eisenhower displayed an unusual ability for organization and diplomacy. Patton, who had chased Pancho Villa in Mexico and led troops in the First World War, seemed destined for high command and outranked his two friends for years. But with the arrival of World War II, it was Eisenhower who attained the role of Supreme Commander, with Patton and Bradley as his subordinates. Jonathan W. Jordan’s New York Times bestselling Brothers Rivals Victors explores this friendship that waxed and waned over three decades and two world wars, a union complicated by rank, ambition, jealousy, backbiting and the enormous stresses of command. In a story that unfolds across the deserts of North Africa to the beaches of Sicily, from D-Day to the Battle of the Bulge and beyond, readers are offered revealing new portraits of these iconic generals.
This engaging book examines the history of the one-room school and how successive generations of Americans have remembered--and just as often misremembered--this powerful national icon.
Since the events of September 11, 2001, science and policy analysis necessary to improve public health has taken on new significance. This collection of articles on public health topics deals with epidemiology and biostatistics, environmental and occupational health, public health practice, social environment and behavior, and health services. Specific subjects examined include gambling and related mental disorders, effects of smoking restrictions in the workplace, direct marketing of pharmaceuticals to consumers, the macroeconomic determinants of health, cascade effects of medical technology, and morbidity and mortality from medical errors. Fielding is affiliated with the University California-Los Angeles. Annotation copyrighted by Book News, Inc., Portland, OR.
Comprehensive resource detailing the latest advances in microwave and wireless sensors implemented in planar technology Planar Microwave Sensors is an authoritative resource on the subject, discussing the main relevant sensing strategies, working principles, and applications on the basis of the authors’ own experience and background, while also highlighting the most relevant contributions to the topic reported by international research groups. The authors provide an overview of planar microwave sensors grouped by chapters according to their working principle. In each chapter, the working principle is explained in detail and the specific sensor design strategies are discussed, including validation examples at both simulation and experimental level. The most suited applications in each case are also reported. The necessary theory and analysis for sensor design are further provided, with special emphasis on performance improvement (i.e., sensitivity and resolution optimization, dynamic range, etc.). Lastly, the work covers a number of applications, from material characterization to biosensing, including motion control sensors, microfluidic sensors, industrial sensors, and more. Sample topics covered in the work include: Non-resonant and resonant sensors, reflective-mode and transmission-mode sensors, single-ended and differential sensors, and contact and contactless sensors Design guidelines for sensor performance optimization and analytical methods to retrieve the variables of interest from the measured sensor responses Radiofrequency identification (RFID) sensor types, prospective applications, and materials/technologies towards “green sensors” implementation Comparisons between different technologies for sensing and the advantages and limitations of microwave sensors, particularly planar sensors Engineers and qualified professionals involved in sensor technologies, along with undergraduate and graduate students in related programs of study, can harness the valuable information inside Planar Microwave Sensors to gain complete foundational knowledge on the subject and stay up to date on the latest research and developments in the field.
The 8 chapters in this book have been selected from the contents of the Paediatric Imaging section in Grainger & Allison's Diagnostic Radiology 6e. These organ-specific chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed.
A state-of-the-art psychological perspective on team working and collaborative organizational processes This handbook makes a unique contribution to organizational psychology and HRM by providing comprehensive international coverage of the contemporary field of team working and collaborative organizational processes. It provides critical reviews of key topics related to teams including design, diversity, leadership, trust processes and performance measurement, drawing on the work of leading thinkers including Linda Argote, Neal Ashkanasy, Robert Kraut, Floor Rink and Daan van Knippenberg.
**Selected for Doody's Core Titles® 2024 in Transplantation Surgery** From basic science to practical clinical tools, Chronic Kidney Disease, Dialysis, and Transplantation, 4th Edition provides you with the up-to-date, authoritative guidance you need to safely and effectively manage patients with chronic renal disease. Covering all relevant clinical management issues, this companion volume to Brenner and Rector's The Kidney presents the knowledge and expertise of renowned researchers and clinicians in the fields of hemodialysis, peritoneal dialysis, critical care nephrology, and transplantation – for an all-in-one, indispensable guide to every aspect of this fast-changing field. - Contains expanded content on economics and outcomes of treatment, as well as acute kidney injury. - Covers hot topics such as the genetic causes of chronic kidney disease, ethical challenges and palliative care, and home hemodialysis. - Discusses the latest advances in hypertensive kidney disease, vitamin D deficiency, diabetes management, transplantation, and more. - Provides a clear visual understanding of complex information with high-quality line drawings, photographs, and diagnostic and treatment algorithms. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
This volume in the Chemistry of Heterocyclic Compounds series presents a comprehensive review of the quinoxaline literature from 1975 to the present (2002), updating Volumes 5 and 35. It provides an alphabetical table of known simple quinoxalines, including new compounds discussed in this volume and their physical data, as well as the pyrazines from the original volumes. Biological activities, spectral or other physical studies, and other such materials appear at appropriate points in the text. The in-depth coverage includes synthesis, reactions, spectroscopic, and physical properties for each class of compounds. Chemistry of Heterocyclic Compounds, Volume 61: Supplement II provides the most up-to-date summation of knowledge of the synthetic chemistry of quinoxalines.
OKU 12 brings you a comprehensive synthesis of the latest clinical thinking and best practices across all orthopaedic specialty areas. Keep pace with the rapidly changing body of orthopaedic knowledge and clinical practice with OKU’s objective, balanced coverage in easily accessible formats, including new on-demand, fully-searchable digital versions.
In the proud tradition of drunken writers everywhere . . . comes the tale of Jonathan A., a boozed-up, coked-out, sexually confused, hopelessly romantic-and of course, entirely fictional-novelist who bears only a coincidental resemblance to real-life author Jonathan Ames, critically acclaimed author of Wake Up, Sir!, The Extra Man, and What's Not to Love as well as HBO's Bored to Death and Starz's Blunt Talk Featuring gritty, yet poignant artwork by Dean Haspiel (The Quitter), The Alcoholic marks Ames' hilarious yet heartbreaking graphic novel debut. This tenth anniversary edition hardcover also features a new afterword by Jonathan Ames as well as a special behind-the-scenes artist section!
Reading the Renaissance, first published in 1996, is a collection of essays discussing the literature, drama, poetics and culture of the Renaissance period. The Renaissance, which extends from about 1300 to 1700 depending on the country, was originally a rebirth of the arts but has also come to apply to the wider cultural change in the face of modernization. The essays represent a plural Renaissance and explore the boundaries between genre and gender, languages and literatures, reading and criticism, the Renaissance and the medieval, the early modern and the postmodern, world and theatre. There is also a plurality of methods that is fitting for the variety of topics and the richness of the Renaissance. This book is ideal for students of literature and theatre studies.
Ideal for psychology, food science and nutrition students at a variety of levels, this text provides a unique lifespan perspective to guide students through nutrition and cognitive performance. With contributions from leading academics and professionals, it is an accessible and comprehensive guide to the connection between psychology and nutrition.
Thorough, up to date, and unique in the field, Comprehensive Textbook of Eyelid Disorders and Diseases, by Drs. Jonathan J. Dutton, Hatem A. Tawfik, and Alan D. Proia, offers a complete up-to-date review of the most common eyelid disorders. In 147 chapters, the authors provide highly illustrated discussions of each condition, suitably detailed for ophthalmologists working in oculoplastics, neuro-ophthalmology, and pediatrics, as well as facial surgeons, dermatologists, and dermatopathologists.
Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods. Topics covered include: Reduction of alkenes, ketones and imines Nucleophilic addition to carbonyl compounds Catalytic carbon-carbon bond forming reactions Catalytic reactions involving metal carbenoids Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.
Henry Purcell (1659-1695) is the greatest of all English composers and a pivotal figure in European musical history. In this rich and colorful biography, Jonathan Keates deftly traces Purcell's life and artistry against the backdrop of the turbulent political, religious, theatrical, and social movements of his time. Purcell's musical genius both embraced and transcended the variable moods and tensions of Restoration England, and gave the period and the culture an unforgettable voice. With great skill and historical understanding, Keates follows Purcell through his extraordinarily prolific career, from chorister at the Chapel Royal, to composer for the theater and the court, to writer of sacred music, chamber music, and the triumphant Dido and Aeneas, the first British opera. Keates considers Purcell's musical studies with Pelham Humfrey and John Blow as well as his adaptation of Matthew Locke's innovative and colorful style. He provides a superb critical appreciation of Purcell's music in all its forms. Keates also discusses the musical history of the period, including the influence of French and Italian composers, whose music blended with and modified native traditions.
Written by experts in the field, Advanced Exercise Physiology: Essential Concepts and Applications builds upon foundational topics and looks further into key physiological components to help advanced students gain a deeper level of understanding.
Covering the entire spectrum of women’s healthcare , Berek & Novak’s Gynecology, 16th Edition, provides definitive information and guidance for trainees and practicing physicians. A newly streamlined design and brilliant, full-color illustrations highlight must-know content on principles of practice and initial assessment, including relevant basic science; preventive and primary care for women; and methods of diagnosis and management in general gynecology, operative gynecology, urogynecology and pelvic reconstructive surgery, early pregnancy issues, reproductive endocrinology, and gynecologic oncology.
This issue of Medical Clinics covers the current best practices surrounding the perioperative management of patients with chronic diseases. Guest edited by Jeffrey Kirsch and Ansgar Brambrink, the topics covered will include patients with pacemakers, patients with endocrine disease, immunocompromised patients, patients with heart disease, patients with renal disease, and more.
The Civil War brought many forms of upheaval to America, not only in waking hours but also in the dark of night. Sleeplessness plagued the Union and Confederate armies, and dreams of war glided through the minds of Americans in both the North and South. Sometimes their nightly visions brought the horrors of the conflict vividly to life. But for others, nighttime was an escape from the hard realities of life and death in wartime. In this innovative new study, Jonathan W. White explores what dreams meant to Civil War–era Americans and what their dreams reveal about their experiences during the war. He shows how Americans grappled with their fears, desires, and struggles while they slept, and how their dreams helped them make sense of the confusion, despair, and loneliness that engulfed them. White takes readers into the deepest, darkest, and most intimate places of the Civil War, connecting the emotional experiences of soldiers and civilians to the broader history of the conflict, confirming what poets have known for centuries: there are some truths that are only revealed in the world of darkness.
This book brings together, for the first time, a selection of international critiques on the role of ADHD in our society today, looking at how diagnoses have increased in recent years and the reasons behind this. Topics range from genetics to social culture, offering a comprehensive overview of this area.
The Allergy Solution is a game changer." — David Perlmutter, M.D., #1 New York Times best-selling author of Grain Brain An epidemic of allergies is spreading around the world. One billion people suffer from allergic diseases such as asthma, hay fever, eczema, and food allergies. But this is just the tip of the iceberg. In this eye-opening book, award-winning integrated-medicine expert Leo Galland, M.D., reveals the shocking rise of hidden allergies that lead to weight gain, fatigue, brain fog, depression, joint pain, headaches, ADHD, digestive problems, and much more. Astonishing new research shows how each of these is linked to the immune imbalance that is at the root of allergy. A brilliant clinician, Dr. Galland has unlocked the power of this breakthrough science to help thousands of patients who have struggled with mysterious symptoms answer the question: "Doctor, what’s wrong with me?" In The Allergy Solution, he is joined by his son, Jonathan Galland, J.D., a passionate health writer and environmental advocate, in exposing the truth that just as the earth’s environment is out of balance, our bodies are out of balance. The modern world, with pollution, unhealthy eating habits, lack of exercise, and excessive exposure to antibiotics, is fueling the rise in allergies.The Allergy Solution takes an in-depth look at how we can balance immunity through nutrition and lifestyle to reverse allergies without drugs. It offers an easy nutritional program, starting with a Three-Day Power Wash designed to "clear the tracks," to help us take back control. Do you suffer from asthma, eczema, or sinusitis? Are you sick of pain, fatigue, brain fog, weight gain, depression, anxiety, or wondering what is behind your mysterious symptoms? Let Dr. Galland’s clinical experience and unique insights into cutting-edge science guide you back to health.
This issue of Dermatologic Clinics, guested edited by Drs.Jonathan I. Silverberg and Nanette Silverberg, is devoted to Atopic Dermatitis. Articles in this outstanding issue include: How to Define Atopic Dermatitis; Public Health Burden and Epidemiology of Atopic Dermatitis; Long-term Course of Atopic Dermatitis; Allergic and Non-Allergic Comorbidities of Atopic Dermatitis; Patient-burden of Atopic Dermatitis; Assessment of Atopic Dermatitis Severity in Clinical Practice; An Update on the Pathophysiology of Atopic Dermatitis; Long-term Treatment of Atopic Dermatitis; Special Considerations for Management of Atopic Dermatitis in Young Children; Management of Adult Onset Atopic Dermatitis; Management of Atopic Hand Dermatitis; Adjunctive Management of Itch in Atopic Dermatitis; and Racial and Ethnic Differences of Atopic Dermatitis.
As the profession of clinical exercise physiology continues to evolve, there is one cornerstone text that evolves along with it. Clinical Exercise Physiology, Fourth Edition With Web Resource, has been a mainstay in the field since its inception in 2003, and the revisions and additions to this latest rendition reinforce its elite status. As the most comprehensive resource available, Clinical Exercise Physiology, Fourth Edition, provides greater coverage and depth of diseases than is typically found in most clinical exercise physiology textbooks. It thoroughly examines the effects of exercise on chronic disease and then investigates 24 chronic conditions, covering the scope of each disease as well as the pathophysiology, medications, and clinical applications. It also examines clinical considerations and exercise prescriptions for four special populations. This fourth edition reflects the latest American College of Sports Medicine (ACSM) standards and guidelines, making it an ideal resource for candidates preparing for ACSM Clinical Exercise Physiologist certification. In addition to updated content that aligns with current science and evidence-based practice guidelines, the fourth edition also incorporates the following: • A closer and more up-to-date look at the state of the profession • A new web resource featuring case studies that depict real-life scenarios • A new chapter on Parkinson’s disease • Enhanced coverage of exercise testing and exercise prescription, in separate chapters to delve deeper into each of those topics • An expanded chapter on end-stage renal disease, to more broadly cover chronic kidney disease • Significant revisions to chapters on metabolic syndrome, diabetes, and heart failure The online case studies are written in the form of SOAP (Subjective, Objective, Assessment, Plan) notes, reflecting common medical chart documentation, to help readers experience realistic examples. The text also offers Practical Application sidebars in each chapter; some of these sidebars focus on exercise prescription, and other Practical Application sidebars review the relevant literature related to physiological adaptations to exercise training. To aid in course preparation, instructors are provided a test package, chapter quizzes, and a presentation package plus image bank. Clinical Exercise Physiology, Fourth Edition, offers a contemporary review of the variety of diseases and conditions that students and professionals may encounter in the field. New and veteran clinical exercise physiologists alike, as well as those preparing for ACSM certification exams, will appreciate the in-depth coverage of the clinical populations that benefit from physical activity and exercise.
African literature, like the continent itself is enormous and diverse. East Africa's literature is different from West Africa's which is quite different from South Africa's which has different influences on it than North Africa's. Africa's literature is based on a widespread heritage of oral literature, some of which has now been recorded. Arabic influence can be detected as well as European, especially French and English. Legends, myths, proverbs, riddles and folktales form the mother load of the oral literature. This book presents an overview of African literature as well as a comprehensive bibliography, primarily of English language sources. Accessed by subject, author and title indexes.
The Union army's overwhelming vote for Abraham Lincoln's reelection in 1864 has led many Civil War scholars to conclude that the soldiers supported the Republican Party and its effort to abolish slavery. In Emancipation, the Union Army, and the Reelection of Abraham Lincoln Jonathan W. White challenges this reigning paradigm in Civil War historiography, arguing instead that the soldier vote in the presidential election of 1864 is not a reliable index of the army's ideological motivation or political sentiment. Although 78 percent of the soldiers' votes were cast for Lincoln, White contends that this was not wholly due to a political or social conversion to the Republican Party. Rather, he argues, historians have ignored mitigating factors such as voter turnout, intimidation at the polls, and how soldiers voted in nonpresidential elections in 1864. While recognizing that many soldiers changed their views on slavery and emancipation during the war, White suggests that a considerable number still rejected the Republican platform, and that many who voted for Lincoln disagreed with his views on slavery. He likewise explains that many northerners considered a vote for the Democratic ticket as treasonous and an admission of defeat. Using previously untapped court-martial records from the National Archives, as well as manuscript collections from across the country, White convincingly revises many commonly held assumptions about the Civil War era and provides a deeper understanding of the Union Army.
This groundbreaking core textbook offers a comprehensive overview of different approaches to the causes, assessment and treatment of psychological disorders. The book includes important diagnostic frameworks, including the new DSM-5-TR, ICD-11 and PDM, but also widens the scope of coverage beyond mainstream psychiatric models to include psychological, biological, historical, sociocultural and therapeutic approaches. Contemporary and well-balanced, this book provides an even-handed and holistic foundation, allowing students to develop a strong critical mindset while retaining a robust research-driven orientation. This new edition: - features an innovative structure organized by presenting problem, examining each in a broad context of traditional psychiatric and alternative approaches - is grounded in lived experience of disorder: shining a spot-light on service-users through 'Case Examples' scenarios and 'Lived Experience' perspective pieces - Supports student learning and critical thinking through engaging 'Controversial Question' and 'In Depth' features - Features an attractive new layout and plenty of colour illustrations - Is supported by impressive online support features including lecture slides, a test bank, instructor manual, video library, student study questions, self-test quizzes, flashcard activities and more. Now thoroughly updated to include the latest developments in research and clinical practice, along with enhanced in-text and online pedagogy to support instructors and learners, this book is ideal for undergraduate and graduate students on abnormal psychology, psychopathology, mental health or clinical psychology courses.
Since its first edition over 60 years ago, Rockwood and Wilkins’ Fractures in Children has been the go-to reference for treating a wide range of fractures in children and adolescents. The landmark tenth edition continues this tradition with the addition of four associate editors, a refreshed mix of contributors, and fully revised content throughout, bringing you fully up to date with today’s techniques and technologies in fractures in pediatric orthopaedics. Drs. Peter M. Waters, David L. Skaggs, John M. Flynn, Lindsay Andras, Donald S. Bae, Keith D. Baldwin, and Jonathan G. Schoenecker lead a team of experts who ensure that the most up-to-date information is presented in a comprehensive yet easy to digest manner.
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