Jon E. Sprague's Books

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

By: David F. Kisor,Professor of Pharmacokinetics Chair Department of Pharmaceutical and Biomedical Sciences Ohio Northern University Raabe College of Pharmacy David F Kisor,Michael D. Kane,Jon E. Sprague,Jeffery N. Talbot

Write a review Read reviews Take a Quiz Solve Book Puzzle

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine provides a primer to understand pharmacogenetics (the study of genetic factors that influence how a drug works) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, that is, "personalized medicine." Through specific drug examples, this resource explores how the genetic constitution of an individual may lead to the need for an altered dose or in some cases alternative drug therapy. Real-world cases highlight the specific relationships between genetics, drug action, and the body's response as well as adverse drug reactions, altered metabolism, and drug efficacy. Ethical issues concerning pharmacogenomics and study design are also discussed in this concise overview.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

225

Publisher

Jones & Bartlett Publishers

Published Date

ISBN 10

1449633943

ISBN 13

9781449633943

Thomas Jefferson: The Art of Power

By: Jon Meacham

Write a review Read reviews Take a Quiz Solve Book Puzzle

Thomas Jefferson: The Art of Power

By: Jon Meacham

NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • The Washington Post • Entertainment Weekly • The Seattle Times • St. Louis Post-Dispatch • Bloomberg Businessweek In this magnificent biography, the Pulitzer Prize–winning author of American Lion and Franklin and Winston brings vividly to life an extraordinary man and his remarkable times. Thomas Jefferson: The Art of Power gives us Jefferson the politician and president, a great and complex human being forever engaged in the wars of his era. Philosophers think; politicians maneuver. Jefferson’s genius was that he was both and could do both, often simultaneously. Such is the art of power. Thomas Jefferson hated confrontation, and yet his understanding of power and of human nature enabled him to move men and to marshal ideas, to learn from his mistakes, and to prevail. Passionate about many things—women, his family, books, science, architecture, gardens, friends, Monticello, and Paris—Jefferson loved America most, and he strove over and over again, despite fierce opposition, to realize his vision: the creation, survival, and success of popular government in America. Jon Meacham lets us see Jefferson’s world as Jefferson himself saw it, and to appreciate how Jefferson found the means to endure and win in the face of rife partisan division, economic uncertainty, and external threat. Drawing on archives in the United States, England, and France, as well as unpublished Jefferson presidential papers, Meacham presents Jefferson as the most successful political leader of the early republic, and perhaps in all of American history. The father of the ideal of individual liberty, of the Louisiana Purchase, of the Lewis and Clark expedition, and of the settling of the West, Jefferson recognized that the genius of humanity—and the genius of the new nation—lay in the possibility of progress, of discovering the undiscovered and seeking the unknown. From the writing of the Declaration of Independence to elegant dinners in Paris and in the President’s House; from political maneuverings in the boardinghouses and legislative halls of Philadelphia and New York to the infant capital on the Potomac; from his complicated life at Monticello, his breathtaking house and plantation in Virginia, to the creation of the University of Virginia, Jefferson was central to the age. Here too is the personal Jefferson, a man of appetite, sensuality, and passion. The Jefferson story resonates today not least because he led his nation through ferocious partisanship and cultural warfare amid economic change and external threats, and also because he embodies an eternal drama, the struggle of the leadership of a nation to achieve greatness in a difficult and confounding world. Praise for Thomas Jefferson: The Art of Power “This is probably the best single-volume biography of Jefferson ever written.”—Gordon S. Wood “A big, grand, absorbing exploration of not just Jefferson and his role in history but also Jefferson the man, humanized as never before.”—Entertainment Weekly “[Meacham] captures who Jefferson was, not just as a statesman but as a man. . . . By the end of the book . . . the reader is likely to feel as if he is losing a dear friend. . . . [An] absorbing tale.”—The Christian Science Monitor “This terrific book allows us to see the political genius of Thomas Jefferson better than we have ever seen it before. In these endlessly fascinating pages, Jefferson emerges with such vitality that it seems as if he might still be alive today.”—Doris Kearns Goodwin

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

802

Publisher

Random House Trade Paperbacks

Published Date

ISBN 10

0812979486

ISBN 13

9780812979480

Salem Secret Underground

The History of the Tunnels in the City

By: Christopher Jon Luke Dowgin

Write a review Read reviews Take a Quiz Solve Book Puzzle

Salem Secret Underground

The History of the Tunnels in the City

By: Christopher Jon Luke Dowgin

In 1801 Elias Hasket Derby Jr. leaves his two year retirement. His father, the country’s first millionaire, has left him a money pit that many would consider one of the nations first American Castles. The expense to keep up this mansion and his leisurely life style has forced Elias back into action. He will take command of the local militia to fill in the ponds in the Common as part of an elaborate plot. The plot would entail the beautification of this neighborhood and entice a series of merchants and ship captains to build a series of two grand brick mansions set apart at fixed distances around the new park. All attached to a series of smuggling tunnels that would lead from the wharf, to their stores, and the banks. An elaborate scheme filled with Masons,pirates, a Secretary of the Navy, Senators, Representatives, a Supreme Court Justice, Presidents, and a touch of murder! Dig into the tunnels of Salem and find the underbelly of our nation!

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

450

Publisher

Salem House Press

Published Date

ISBN 10

0986261033

ISBN 13

9780986261039

Thomas Jefferson: President and Philosopher

By: Jon Meacham

Write a review Read reviews Take a Quiz Solve Book Puzzle

Thomas Jefferson: President and Philosopher

By: Jon Meacham

In this special illustrated edition of the #1 New York Times bestselling Thomas Jefferson: The Art of Power by Pulitzer Prize–winning author Jon Meacham, young readers will learn about the life and political philosophy of one of our Founding Fathers. This book is a must-read for President's Day! Thomas Jefferson was the third president of the United States. He was one of the authors of the Declaration of Independence. But he was also a lawyer and an ambassador, an inventor and a scientist. He had a wide range of interests and hobbies, but his consuming interest was the survival and success of the United States. This book contains a note from Meacham and over 100 archival illustrations, as well as sections throughout the text about subjects such as the Boston Tea Party, the Library of Congress, and Napoléon Bonaparte. Additional materials include a time line; a family tree; a Who’s Who in Jefferson’s world; sections on Jefferson’s original writings and correspondence, “inventions,” interests, places in Jefferson’s world, finding Jefferson in the United States today, additional reading, organizations, and websites; notes; a bibliography; and an index. This adaptation, ideal for those interested in American presidents, biographies, and the founding of the American republic, is an excellent example of informational writing and reflects Meacham’s extensive research using primary source material. Praise for Thomas Jefferson: President and Philosopher “A solid resource for young people intrigued by Jefferson.” –Booklist “Comprehensive and engaging.” –Scholastic Instructor “There is a surprising paucity of books about Jefferson at this level and this handsome, well-written, and engaging volume fills that literary gap.” –Horn Book “Wonderfully written and crafted... Entertaining for both kids and adults alike.” –KidsReads.com

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

338

Publisher

Yearling

Published Date

ISBN 10

0385387520

ISBN 13

9780385387521

Book's by Jon E. Sprague

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine

Thomas Jefferson: The Art of Power

Thomas Jefferson: The Art of Power

Salem Secret Underground

Salem Secret Underground

Thomas Jefferson: President and Philosopher

Thomas Jefferson: President and Philosopher

Username

Password

Username

Password

Password again

Birthday

Email