Progress in Heterocyclic Chemistry (PHC), Volume 28 is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on new and developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 28 are all written by leading researchers and constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry during 2015. Additional articles in this volume include Semi-conjugated Heteroaromatic Rings and beta-Lactam Chemistry. As with previous volumes in the series, Volume 28 will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way. - Recognized as the premiere review of heterocyclic chemistry - Includes contributions from leading researchers in the field - Provides a systematic survey of the important 2015 heterocyclic chemistry literature - Presents articles on new and developing topics of interest to heterocyclic chemists
Designing new products and improving existing ones is a continual process. Industrial design engineering is an industrial engineering process applied to product designs that are to be manufactured through techniques of production operations. Excellent industrial design engineering programs are essential for the nation’s industry to succeed in selling useful and ecologically justifiable and usable products on a market flooded with goods and services. This unique text on industrial design engineering integrates basic knowledge, insight, and working methods from industrial engineering and product design subjects. Industrial Design Engineering: Inventive Problem Solving provides a combination of engineering thinking and design skills that give the researchers, practitioners, and students an excellent foundation for participation in product development projects and techniques for establishing and managing such projects. The design principles are presented around examples related to the designing of products, goods, and services. Case studies are developed around real problems and are based on the customer’s needs.
A familial disorder that causes psychosis is described. Associated with the disorder are distinct patterns of physical symptoms and conditions that may be used to assist diagnosis. The proband carries genetic markers that link the disorder to schizophrenia in Irish high density schizophrenia families. The genetic and metabolic derangements underpinning the disorder are analysed and potentially linked. Evidence is considered which supports a working hypothesis in which haplotype SNPs located at IL3 and/or ACSL6 at 5q31.1 result in or from the failure or partial failure of one or more ERE to activate a pathway leading from P5CS to proline.
The current volume continues the tradition of the Organic Syntheses series, providing carefully checked and edited experimental procedures that describe important synthetic methods, transformations, reagents, and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. These significant and interesting procedures should prove worthwhile to many synthetic chemists working in increasingly diverse areas. A trusted guide for professionals in organic and medicinal chemistry in academia, government, and industries, including pharmaceuticals, fine chemicals, agrochemicals, and biotechnological products.
An in-depth look at what microplastics are, how prevalent they are, and what can be done about them for a professional and academic audience. The first part of the book provides an overview of plastics types, how they are released to the environment, and how they interact with organisms. This part also provides a background for several salient aspects of microplastics hazards (e.g., attachment of toxic chemicals, toxicity to organisms). Special attention will be paid to how microplastics decompose in the environment (which is significant in terms of mobility of toxicity). Subsequent chapters address how to sample and identify microplastics. The second part of the book examines technologies for removal of microplastics from water, wastewater, and soil. Biological, chemical, and physical technologies are presented--technologies that can destroy minute plastics or convert them into benign products. Theory of operation, practical considerations, and possible environmental impacts of their use are discussed. Key aspects include: * technologies available for removal of microplastics from wastewater and surface water; * how various toxins which are sorbed to microplastics adversely affect wastewater treatment processes; * technologies at the pilot- and field stage for removal of microplastics from sediment; and * the distribution of microplastics in the atmosphere. Written by John Pichtel, author of the acclaimed Fundamentals of Site Remediation, and Mathew Simpson.
This book offers both a practical as well a theoretical approach to Solvent Microextraction (SME) and will help analytical chemists to evaluate SME for a given sample preparation. Introductory chapters overview a comparison of SME with other sample preparation methods, a summary of the technical aspects, and a detailed theoretical treatment of SME. The book then describes the practical aspects of the technique, with detailed “how to” chapters devoted to the preparation and analysis of atmospheric, solid and liquid environmental, clinical and industrial samples. This text will serve as both a handy laboratory desk-reference and an indispensible instructional tool.
Wind Turbines and Aerodynamics Energy Harvesters not only presents the most research-focused resource on aerodynamic energy harvesters, but also provides a detailed review on aeroacoustics characteristics. The book considers all developing aspects of 3D printed miniature and large-size Savonious wind harvesters, while also introducing and discussing bladeless and aeroelastic harvesters. Following with a review of Off-shore wind turbine aerodynamics modeling and measurements, the book continues the discussion by comparing the numerical codes for floating offshore wind turbines. Each chapter contains a detailed analysis and numerical and experimental case studies that consider recent research design, developments, and their application in practice. Written by an experienced, international team in this cross-disciplinary field, the book is an invaluable reference for wind power engineers, technicians and manufacturers, as well as researchers examining one of the most promising and efficient sources of renewable energy. - Offers numerical models and case studies by experienced authors in this field - Contains an overview and analysis of the latest research - Explores 3D printing technology and the production of wind harvesters for real applications - Includes, and uses, ANSYS FLUENT case files
Illustrated throughout and featuring the most up-to-date biological information available, this volume is a complete overview of the Chinese alligator, a conservation and cultural icon.
Engineers must possess a range of business communication skills that enable them to effectively communicate the purpose and relevance of their idea, process, or technical design. This unique business communication text is packed with practical advice that will improve your ability to- Market ideas Write proposals Generate enthusiasm for research De
Covering the prediction of outcomes for engineering decisions through regression analysis, this succinct and practical reference presents statistical reasoning and interpretational techniques to aid in the decision making process when faced with engineering problems. The author emphasizes the use of spreadsheet simulations and decision trees as important tools in the practical application of decision making analyses and models to improve real-world engineering operations. He offers insight into the realities of high-stakes engineering decision making in the investigative and corporate sectors by optimizing engineering decision variables to maximize payoff.
This volume contains a collection of papers delivered by the partici pants at the second Conference on Computation and Control held at Mon tana State University in Bozeman, Montana from August 1-7, 1990. The conference, as well as this proceedings, attests to the vitality and cohesion between the control theorist and the numerical analyst that was adver tised by the first Conference on Computation and Control in 1988. The proceedings of that initial conference was published by Birkhiiuser Boston as the first volume of this same series entitled Computation and Control, Proceedings of the Bozeman Conference, Bozeman, Montana, 1988. Control theory and numerical analysis are both, by their very nature, interdisciplinary subjects as evidenced by their interaction with other fields of mathematics and engineering. While it is clear that new control or es timation algorithms and new feedback design methodologies will need to be implemented computationally, it is likewise clear that new problems in computational mathematics arise when implementing a new generation of control algorithms. For these reasons, computational mathematics is mov ing to the forefront in recent developments in modern control theory and conversely control theory and its applications continue to be a fertile area for computationalists. This volume contains a representative cross section of the interdisciplinary blend of analytic and numerical techniques that of ten occur between advanced control design and practical numerical solution of lumped and distributed parameter systems.
The third Conference on Computation and Control was held at Montana State University in Bozeman, Montana from August 5-11, 1992, and this contains a collection of papers addressing issues including noise abatement via smart material technology, robotic vision and parameter identification.
Since the birth of civilisation, human beings have manipulated other life-forms. We have selectively bred plants and animals for thousands of years to maximise agricultural production and cater to our taste in pets. The observation of the creation of artificial animal and plant variants was a key stimulant for Charles Darwin's theory of evolution. The ability to directly engineer the genomes of organisms first became possible in the 1970s, when the gene for human insulin was introduced into bacteria to produce this protein for diabetics. At the same time, mice were modified to produce human growth hormone, and grew huge as a result. But these were only our first tottering steps into the possibilities of genetic engineering. In the past few years, the pace of progress has accelerated enormously. We can now cut and paste genes using molecular scissors with astonishing ease, and the new technology of genome editing can be applied to practically any species of plants or animals. 'Mutation chain reaction' can be used to alter the genes of a population of pests, such as flies; as the modified creatures breed, the mutation is spread through the population, so that within a few generations the organism is almost completely altered. At the same time, scientists are also beginning to synthesize new organisms from scratch. These new technologies hold much promise for improving lives. Genome editing has already been used clinically to treat AIDS patients, by genetically modifying their white blood cells to be resistant to HIV. In agriculture, genome editing could be used to engineer species with increased food output, and the ability to thrive in challenging climates. New bacterial forms may be used to generate energy. But these powerful new techniques also raise important ethical dilemmas and potential dangers, pressing issues that are already upon us given the speed of scientific developments. To what extent should parents be able to manipulate the genetics of their offspring — and would designer babies be limited to the rich? Can we effectively weigh up the risks from introducing synthetic lifeforms into complex ecosystems? In this extensively revised paperback edition, John Parrington explains the nature and possibilities of these new scientific developments, which could usher in a brave, new world. We must rapidly come to understand its implications if we are to direct its huge potential to the good of humanity and the planet.
Proceedings from a 2016 sustainability symposium Information from REWAS 2016 proceedings were collected and published in REWAS 2016: Towards Materials Resource Sustainability. This collection covers the proceedings of the symposium sponsored by the Recycling and Environmental Technologies Committee; the Materials and Society Committee; the Extracting & Processing Division; and the Light Metals Division of the Minerals, Metals and Materials Society. Topics covered include: enabling and understanding the sustainability related to ferrous and non-ferrous metals processing; batteries; rare earth element applications; and building materials. At REWAS 2016, materials professionals exchanged ideas with other researchers and stakeholders to outline a path toward a resource-efficient society.
We may be standing on the precipice of a revolution in propulsion not seen since the internal combustion engine replaced the horse and buggy. The anticipated proliferation of electric cars will influence the daily lives of motorists, the economies of different countries and regions, urban air quality and global climate change. If you want to understand how quickly the transition is likely to occur, and the factors that will influence the predictions of the pace of the transition, this book will be an illuminating read.
Recent developments in DNA marker technologies, in particular the emergence of Single Nucleotide Polymorphism (SNP) discovery, have rendered some of the traditional methods of genetic research outdated. Next Generation Sequencing and Whole Genome Selection in Aquaculture comprehensively covers the current state of research in whole genome selection and applies these discoveries to the aquaculture industry specifically. The text begins with a thorough review of SNP and transitions into topics such as next generation sequencing, EST data mining, SNP quality assessment, and whole genome selection principles. Ending with a discussion of the technology's specific applications to the industry, this text will be a valuable reference for those involved in all aspects of aquaculture research. Special Features: Unique linking of SNP technologies, next generation sequencing technologies, and whole genome selection in the context of aquaculture research Thorough review of Single Nucleotide Polymorphism and existing research 8-page color plate section featuring detailed illustrations
Animal Locomotion: Physical Principles and Adaptations is a professional-level, state of the art review and reference summarizing the current understanding of macroscopic metazoan animal movement. The comparative biophysics, biomechanics and bioengineering of swimming, flying and terrestrial locomotion are placed in contemporary frameworks of biodiversity, evolutionary process, and modern research methods, including mathematical analysis. The intended primary audience is advanced-level students and researchers primarily interested in and trained in mathematics, physical sciences and engineering. Although not encyclopedic in its coverage, anyone interested in organismal biology, functional morphology, organ systems and ecological physiology, physiological ecology, molecular biology, molecular genetics and systems biology should find this book useful.
SiGe HBTs are the most mature of the Si heterostructure devices and not surprisingly the most completely researched and discussed in the technical literature. However, new effects and nuances of device operation are uncovered year-after-year as transistor scaling advances and application targets march steadily upward in frequency and sophistication. Providing a comprehensive treatment of SiGe HBTs, Silicon Heterostructure Devices covers an amazingly diverse set of topics, ranging from basic transistor physics to noise, radiation effects, reliability, and TCAD simulation. Drawn from the comprehensive and well-reviewed Silicon Heterostructure Handbook, this text explores SiGe heterojunction bipolar transistors (HBTs), heterostructure FETs, various other heterostructure devices, as well as optoelectronic components. The book provides an overview, characteristics, and derivative applications for each device covered. It discusses device physics, broadband noise, performance limits, reliability, engineered substrates, and self-assembling nanostructures. Coverage of optoelectronic devices includes Si/SiGe LEDs, near-infrared detectors, photonic transistors for integrated optoelectronics, and quantum cascade emitters. In addition to this substantial collection of material, the book concludes with a look at the ultimate limits of SiGe HBTs scaling. It contains easy-to-reference appendices on topics including the properties of silicon and germanium, the generalized Moll-Ross relations, and the integral charge-control model, and sample SiGe HBT compact model parameters.
Offering focused, practical, and up-to-date content on immunotherapies used to treat a wide variety of cancer types, Clinical Immuno-Oncology covers the basic cellular and molecular mechanisms involved in cancer initiation and progression. The text reviews the development of tumor specific antigens and the challenges of developing cancer immunotherapies. Every effort is made to relate the fundamental aspects of host immunity to the efficacy of current immunotherapies and how they work in conjunction with the immune system to combat cancer. This foundational resource explains the basics of cancer immunotherapy, discusses best practices, and provides recommendations from experienced clinicians in the field. Dr. John E. Niederhuber and a team of expert contributing authors provide clinically focused information essential for integrating these new therapies into practice—making this an ideal resource for fellows, practitioners, and other cancer team members in medical oncology, radiation oncology, cancer surgery, immunology, and cancer research. - Offers balanced and synthesized content on clinical science, clinical and translational research, and evidence-based practice for cutting-edge immunotherapies. - Discusses clinical applications of immunotherapies in common types of cancer including melanoma, breast cancer, pancreatic cancer, colon and rectum cancer, prostate cancer, leukemias, and hematologic malignancies. - Includes dedicated chapters on immune responses, innate immunity, active immunization against cancer, and cell-based therapies by leading experts. - Covers key topics such as cancer immunotherapy in the presence of COVID-19, immunotherapeutics, new findings concerning the role of the microbiome in immunotherapy, advances in engineered cell-based therapies, and active immunization against cancer.
Environmental Chemicals Desk Reference is a concise version of the widely read Agrochemicals Desk Reference and Groundwater Chemicals Desk Reference. This up-to-date volume was inspired by the need for a combination of the material in both references, together with the large number of research publications and the continued interest in the fate, transport, and remediation of hazardous substances. Much new data has been added to this unique edition, including global legislation (REACH) and sustainability, thereby reflecting the wealth of literature in the field. Featured are environmental and physical/chemical data on more than 200 compounds, including pesticides, herbicides, and fungicides.
Going "green" is becoming a major component of the mission for electronics manufacturers worldwide. While this goal seems simplistic, it poses daunting dilemmas. Yet, to compete effectively in the global economy, manufacturers must take the initiative to drive this crucial movement. Green Electronics Manufacturing: Creating Environmental Sensible Products provides you with a complete reference to design, develop, build, and install an electronic product with special consideration for the product’s environmental impacts during its whole life cycle. The author discusses how to integrate the state-of-the-art technologies of finite element method (FEM) modeling, simulation, and testing to create environmental sensible products of satisfying global environmental regulations, such as Restriction of Hazardous Substances (ROHS) compliance. He covers enabling techniques such as advanced fatigue life modeling, crack propagation analysis, and probabilistic robust design of lead-free electronics. The book also explores how risk engineering methodology empowers practitioners with effective tools such as buckling analysis of tin whiskers. With its emphasis on reducing parts, rationing materials, and reusing components to make products more efficient to build, green electronics intertwines today’s electronics with manufacturing strategies of global sourcing, concurrent engineering, and total quality. Implemented through product and process design, it can help you achieve sustainability to support future generations and at the same time preserve our natural resources. Green Electronics Manufacturing: Creating Environmental Sensible Products gives you the tools to create environmental sensible products while maintaining electronics quality and reliability.
The Hereditary Cancer Reference gives insight to the young and rapidly expanding field that combines oncology and genetics to achieve risk reduction, early detection, family risk management, and identification targeted treatments. While genetics and oncology are both well-developed knowledge areas, their combination in hereditary cancer yields an opportunity for new works that systemize knowledge for current researchers, practitioners and students. The Hereditary Cancer Reference exams 371 topics through the lens of hereditary cancer. There are no similar books that presents information in this manner. This reference work contains a complete list of terms and definitions which can be easily reference by researchers and clinicians working in this field that need to keep up to date. - Provides conceptual and factual treatments of 371 topics in hereditary cancer - Gives quick access to a comprehensive guide on Hereditary Cancer - Useful reference for researchers and clinicians
A clear-cut introduction to the technique and applications of x-ray absorption spectroscopy X-ray Absorption Spectroscopy is being applied to a widening set of disciplines. Applications started with solid state physics and grew to materials science, chemistry, biochemistry and geology. Now, they cut across engineering materials, environmental science and national heritage — providing very detailed and useful information facilitating understanding and development of materials. This practical guide helps investigators choose the right experiment, carry it out properly and analyze the data to give the best reliable result. It gives readers insights to extract what they need from the world of large-scale experimental facilities like synchrotrons, which seem distant to many laboratory scientists. X-ray Absorption Spectroscopy for the Chemical and Materials Sciences seeks to educate readers about the strengths and limitations of the techniques, including their accessibility. Presented in six sections, it offers chapters that cover: an introduction to X-ray absorption fine structure XAFS; the basis of XAFS; X-ray sources; experimental methods; data analysis and simulation methods; and case studies. A no-nonsense introduction to the technique and applications of x-ray absorption spectroscopy Features Questions to support learning through the book Relevant to all working on synchrotron sources and applications in physics, materials, environment/geology and biomedical materials Four-color representation allows easy interpretation of images and data for the reader X-ray Absorption Spectroscopy for the Chemical and Materials Sciences is aimed at Masters-level and PhD students embarking on X-ray spectroscopy projects as well as scientists in areas of materials characterization.
Completely updated, this new edition uniquely explains how to assess and handle technical risk, schedule risk, and cost risk efficiently and effectively for complex systems that include Artificial Intelligence, Machine Learning, and Deep Learning. It enables engineering professionals to anticipate failures and highlight opportunities to turn failure into success through the systematic application of Risk Engineering. What Every Engineer Should Know About Risk Engineering and Management, Second Edition discusses Risk Engineering and how to deal with System Complexity and Engineering Dynamics, as it highlights how AI can present new and unique ways that failures can take place. The new edition extends the term "Risk Engineering" introduced by the first edition, to Complex Systems in the new edition. The book also relates Decision Tree which was explored in the first edition to Fault Diagnosis in the new edition and introduces new chapters on System Complexity, AI, and Causal Risk Assessment along with other chapter updates to make the book current. Features Discusses Risk Engineering and how to deal with System Complexity and Engineering Dynamics Highlights how AI can present new and unique ways of failure that need to be addressed Extends the term "Risk Engineering" introduced by the first edition to Complex Systems in this new edition Relates Decision Tree which was explored in the first edition to Fault Diagnosis in the new edition Includes new chapters on System Complexity, AI, and Causal Risk Assessment along with other chapters being updated to make the book more current The audience is the beginner with no background in Risk Engineering and can be used by new practitioners, undergraduates, and first-year graduate students.
Condensed matter is one of the most active fields of physics, with a stream of discoveries in areas from superfluidity and magnetism to the optical, electronic and mechanical properties of materials such as semiconductors, polymers and carbon nanotubes. It includes the study of well-characterised solid surfaces, interfaces and nanostructures as well as studies of molecular liquids (molten salts, ionic solutions, liquid metals and semiconductors) and soft matter systems (colloidal suspensions, polymers, surfactants, foams, liquid crystals, membranes, biomolecules etc., including glasses and biological aspects of soft matter. This book presents state-of-the-art research in this exciting field.
Among the most important and exciting current steps forward in geo-engineering is the development of coupled numerical models. They represent the basic physics of geo-engineering processes which can include the effects of heat, water, mechanics and chemistry. Such models provide an integrating focus for the wide range of geo-engineering disciplines. The articles within this volume were originally presented at the inaugural GeoProc conference held in Stockholm and contain a collection of unusually high quality information not available elsewhere in an edited and coherent form. This collection not only benefits from the latest theoretical developments but also applies them to a number of practical and wide ranging applications. Examples include the environmental issues around radioactive waste disposal deep in rock, and the search for new reserves of oil and gas.
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself (the complex of DNA, histones and non-histone proteins referred to as chromatin), and its distribution within a functionally compartmentalized nucleus. This architectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information.
This comprehensive guide to fan-out wafer-level packaging (FOWLP) technology compares FOWLP with flip chip and fan-in wafer-level packaging. It presents the current knowledge on these key enabling technologies for FOWLP, and discusses several packaging technologies for future trends. The Taiwan Semiconductor Manufacturing Company (TSMC) employed their InFO (integrated fan-out) technology in A10, the application processor for Apple’s iPhone, in 2016, generating great excitement about FOWLP technology throughout the semiconductor packaging community. For many practicing engineers and managers, as well as scientists and researchers, essential details of FOWLP – such as the temporary bonding and de-bonding of the carrier on a reconstituted wafer/panel, epoxy molding compound (EMC) dispensing, compression molding, Cu revealing, RDL fabrication, solder ball mounting, etc. – are not well understood. Intended to help readers learn the basics of problem-solving methods and understand the trade-offs inherent in making system-level decisions quickly, this book serves as a valuable reference guide for all those faced with the challenging problems created by the ever-increasing interest in FOWLP, helps to remove roadblocks, and accelerates the design, materials, process, and manufacturing development of key enabling technologies for FOWLP.
This volume brings together work from leading researchers in the fields of developmental disorders of binocular vision, strabismus, and both infantile and acquired forms of nystagmus. It contains four sections. The first section, Basic Concepts of Stable Vision and Gaze, deals with psychophysical aspects of infantile forms of nystagmus and the relative contributions of extraocular proprioception and efference (corollary discharge). It also contains an accessible review of current notions of spatial and temporal visual functions and spatial constancy in infantile nystagmus syndrome and latent nystagmus. The second section, New Models and Techniques for Studying Gaze Stability, reviews animal and development models for strabismus, amblyopia, and nystagmus. It also contains novel optical methods for managing the visual consequences of nystagmus and a study of the potential ill effects of video displays on children's response to near viewing. The third section, New Therapies for Congenital Nystagmus, presents basic genetic studies and clinical trials of drug and surgical treatment of those patients with infantile forms of nystagmus. The final section,General Aspects of Normal and Abnormal Gaze Control, pulls together a range of contributions dealing with normal gaze control, infantile nystagmus, and acquired disorders of eye movements, including new treatment measures. This book will be a valuable resource for all scientists and practitioners interested in developmental disorders of vision.
Birds have and continue to fascinate scientists and the general public. While the avian respiratory system has unremittingly been investigated for nearly five centuries, important aspects on its biology remain cryptic and controversial. In this book, resolving some of the contentious issues, developmental-, structural- and functional aspects of the avian lung-air sac system are particularized: it endeavors to answer following fundamental questions on the biology of birds: how, when and why did birds become what they are? Flight is a unique form of locomotion. It considerably shaped the form and the essence of birds as animals. An exceptionally efficient respiratory system capacitated birds to procure the exceptionally large quantities of oxygen needed for powered (active) flight. Among the extant air-breathing vertebrates, comprising ~11,000 species, birds are the most species-rich-, numerically abundant- and extensively distributed animal taxon. After realizing volancy, they easily overcame geographical obstacles and extensively dispersed into various ecological niches where they underwent remarkable adaptive radiation. While the external morphology of birds is inconceivably uniform for such a considerably speciose taxon, contingent on among other attributes, lifestyle, habitat and phylogenetic level of development have foremost determined the novelties that are displayed by diverse species of birds. Here, critical synthesizes of the most recent findings with the historical ones, evolution and behavior and development, structure and function of the exceptionally elaborate respiratory system of birds are detailed. The prominence of modern birds as a taxon in the Animal Kingdom is underscored. The book should appeal to researchers who are interested in evolutionary processes and how adaptive specializations correlate with biological physiognomies and exigencies, comparative biologists who focus on how various animals have solved respiratory pressures, people who study respiration in birds and other animals and ornithologists who love and enjoy birds for what they are – profoundly interesting animals.
The book focuses on the design, materials, process, fabrication, and reliability of chiplet design and heterogeneous integraton packaging. Both principles and engineering practice have been addressed, with more weight placed on engineering practice. This is achieved by providing in-depth study on a number of major topics such as chip partitioning, chip splitting, multiple system and heterogeneous integration with TSV-interposers, multiple system and heterogeneous integration with TSV-less interposers, chiplets lateral communication, system-in-package, fan-out wafer/panel-level packaging, and various Cu-Cu hybrid bonding. The book can benefit researchers, engineers, and graduate students in fields of electrical engineering, mechanical engineering, materials sciences, and industry engineering, etc.
The Development of Children and Adolescents, by Penny Hauser-Cram, J. Kevin Nugent, Kathleen Thies, and John F. Travers, provides an integrated view of child development. Presenting the most pertinent research for each developmental stage and linking this to practical applications in the areas of Parenting, Policy, and Practice, this balanced approach emphasizes the relationship between research and theory and applications. The rich media program, including WileyPLUS with Real Development promotes active learning and allows for increased understanding and comprehension of the course content. Real Development, authored by Nicole Barnes, Ph.D., Montclair State University and Christine Hatchard, Psy.D., Monmouth University, uses authentic video showcasing real families, along with activities and assessments that put students in the place of a professional, to gain an understanding of key concepts. Through the combination of text and media, students are engaged in meaningful learning that deepens and enriches their understanding of developmental concepts. WileyPLUS sold separately from text.
In today's business world, competitiveness defines the industrial leading edge. Organizations and businesses of all sizes are adopting Lean manufacturing practices to increase efficiency and address worries about their bottom lines. In a detailed review of this staple of Lean manufacturing, Cellular Manufacturing: Mitigating Risk and Uncertainty ou
Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.
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