John W. Phillis's Books

Adenosine and Adenine Nucleotides As Regulators of Cellular Function

By: John W. Phillis

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Adenosine and Adenine Nucleotides As Regulators of Cellular Function

By: John W. Phillis

This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various aspects of the formation, metabolism, release, transport, and receptors for endogenous adenosine and the adenosine triphosphate; functions of purines at the cellular level; the role of adenosine in the regulation of flow in different vascular beds; and angiogenesis. The book also addresses the purinergic regulation of the cardiac, renal, gastro-intestinal, and central nervous system, as well as potential therapeutic avenues for purine use. The book will be valuable to physiologists, pharmacologists, and other basic and clinical scientists interested in updating their knowledge of the expanding biological roles of these substances.

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Page Count

460

Publisher

CRC Press

Published Date

ISBN 10

0849369282

ISBN 13

9780849369285

Novel Therapies for CNS Injuries

Rationales and Results

By: Patti L. Peterson,John W. Phillis

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Novel Therapies for CNS Injuries

Rationales and Results

By: Patti L. Peterson,John W. Phillis

This book provides reviews of the epidemiology, evaluation, and patient management of central nervous system (CNS) injuries. Internationally recognized clinicians and basic scientists discuss recent research that has significantly advanced the understanding of the pathophysiology of neuronal death and facilitated development of new therapeutic approaches. Novel therapeutic agents evaluated in animal models and currently in clinical trials include: calcium antagonists glutamate receptor antagonists inhibitors of glutamate release endothelial adhesion and nerve growth factors opioids antioxidants, gangliosides thrombolytic agents All of these options, as well as hypothermia as a potentially therapeutic approach, are discussed in this comprehensive volume. It will be invaluable to neurologists, neurosurgeons, intensivists, and emergency medicine physicians who care for CNS injured patients.

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Page Count

426

Publisher

CRC Press

Published Date

ISBN 10

0849376521

ISBN 13

9780849376528

Phillis Wheatley and the Romantics

By: John C. Shields

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Phillis Wheatley and the Romantics

By: John C. Shields

Phillis Wheatley was the first African American to publish a book. Born in Gambia in 1753, she came to America aboard a slave ship, the Phillis. From an early age, Wheatley exhibited a profound gift for verse, publishing her first poem in 1767. Her tribute to a famed pastor, “On the Death of the Rev. Mr. George Whitefield,” followed in 1770, catapulting her into the international spotlight, and publication of her 1773 Poems on Various Subjects Religious and Moral in London created her an international star. Despite the attention she received at the time, history has not been kind to Wheatley. Her work has long been neglected or denigrated by literary critics and historians. John C. Shields, a scholar of early American literature, has tried to help change this perception, and Wheatley has begun to take her place among the elite of American writers. In Phillis Wheatley and the Romantic Age, Shields contends that Wheatley was not only a brilliant writer but one whose work made a significant impression on renowned Europeans of the Romantic age, such as Samuel Taylor Coleridge, who borrowed liberally from her works, particularly in his famous distinction between fancy and imagination. Shields shows how certain Wheatley texts, particularly her “Long Poem,” consisting of “On Recollection,” “Thoughts on the Works of Providence,” and “On Imagination,” helped shape the face of Romanticism in the late eighteenth and nineteenth centuries. Phillis Wheatley and the Romantic Age helps demolish the long-held notion that literary culture flowed in only one direction: from Europe to the Americas. Thanks to Wheatley’s influence, Shields argues, the New World was influencing European literary masters far sooner than has been generally understood.

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Page Count

250

Publisher

Univ. of Tennessee Press

Published Date

ISBN 10

1572337125

ISBN 13

9781572337121

Book's by John W. Phillis

Adenosine and Adenine Nucleotides As Regulators of Cellular Function

Adenosine and Adenine Nucleotides As Regulators of Cellular Function

Novel Therapies for CNS Injuries

Novel Therapies for CNS Injuries

Phillis Wheatley and the Romantics

Phillis Wheatley and the Romantics

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