This book develops an original theory of agentive modality: the kind of modality that is distinctive to agents. The central thesis is that the idea of an option should be taken as primitive, and that other agentive notions – such as ability, skill, and free will – should be understood in terms of options. The main contributions of this book are twofold. First, it resolves many of the outstanding questions in the metaphysics and semantics of agentive modality. In doing so, it develops original accounts of topics that have been central to philosophy since Aristotle. It also contributes to a lively contemporary literature on these topics. Second, it articulates an austere and uncompromising form of compatibilism about free will, termed “simple compatibilism.” Simple compatibilism is so-called because it rejects both the reductive theses endorsed by traditional compatibilists and the sophisticated proposals of many contemporary compatibilists. Instead, it turns precisely on insisting that options are analytically simple. Arguments for incompatibilism are shown to rest on auxiliary principles that should, in light of the book’s general account of options, be rejected.
This book defends a comprehensive new vision of what addiction is and how people with addictions should be treated. The author argues that, in addition to physical and intellectual disabilities, there are volitional disabilities – disabilities of the will – and that addiction is best understood as a species of volitional disability. This theory serves to illuminate long-standing philosophical and psychological perplexities about addiction and addictive motivation. It articulates a normative framework within which to understand prohibition, harm reduction, and other strategies that aim to address addiction. The argument of this book is that these should ultimately be evaluated in terms of reasonable accommodations for addicted people and that the priority of addiction policy should be the provision of such accommodations. What makes this book distinctive is that it understands addiction as a fundamentally political problem, an understanding that is suggested by standard legal approaches to addiction, but which has not received a sustained defense in the previous philosophical or psychological literature. This text marks a significant advance in the theory of addiction, one which should reshape our understanding of addiction policy and its proper aims.
The new edition of Electrophysiological Disorders of the Heart helps you diagnose and treat a full range of heart rhythm disorders using today’s latest technologies and therapies. It provides practical, hands-on coverage of hot topics such as pediatric EP, imaging, echocardiography-guided EP procedures, regenerative therapies, cardiac pacing, and more. Now available in a new full-color format, the title also includes easy online access at www.expertconsult.com. Discover new ways to treat and manage the full range of heart rhythm disorders with content focused on common clinical features, diagnosis, and management. Review expert management strategies to help you handle complex patient problems. Stay current with the latest molecular and technical advances as well as new treatment options implemented over the last few years. Use the latest technologies and devices to accurately diagnose and manage heart rhythm disorders. Consult new and expanded coverage of regenerative therapies, echo-guided procedures, cardiac pacing, and CRT, as well as a new section on pediatric electrophysiology and imaging. Enjoy improved visual guidance with many new full-color images. Log on to www.expertconsult.com to easily search the complete contents online and access a downloadable image library.
After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.
This PhD thesis is dedicated to a subfield of elementary particle physics called “Flavour Physics”. The Standard Model of Particle Physics (SM) has been confirmed by thousands of experimental measurements with a high precision. But the SM leaves important questions open, like what is the nature of dark matter or what is the origin of the matter-antimatter asymmetry in the Universe. By comparing high precision Standard Model calculations with extremely precise measurements, one can find the first glimpses of the physics beyond the SM – currently we see the first hints of a potential breakdown of the SM in flavour observables. This can then be compared with purely theoretical considerations about new physics models, known as model building. Both precision calculations and model building are extremely specialised fields and this outstanding thesis contributes significantly to both topics within the field of Flavour Physics and sheds new light on the observed anomalies.
This book, written by international experts, is a detailed guide to the Eustachian tube, with emphasis on those aspects of most relevance to the practitioner. The opening chapters document the clinical anatomy and provide essential information on physiology, with explanation of the new model of tubal mechanics. Diagnosis and therapy for the patulous Eustachian tube are then discussed, placing special emphasis on a novel conservative treatment regimen that has proven to be a breakthrough for patients with this clinical syndrome. A further extensive chapter examines overall function of the Eustachian tube, primarily from the middle ear surgeon’s viewpoint. Tuboplasty procedures, including laser tuboplasty, and tympanoplasty are described, and the implications of different middle ear pathologies for surgical treatment are explained. The previously unpublished treatment methods that are described in this book will be invaluable in ensuring the best possible clinical outcomes.
This succinct, evidence-based book delivers everything you need to provide safe, effective care to pregnant women in subacute and emergency situations A quick-reference guide designed for on-the-spot clinical guidance, Obstetric Anesthesia: Quick References & Practical Guides fills a gap in the current literature by distilling the information of a comprehensive textbook into a quick review and provides standard instructions that can be integrated into everyday practice. You'll find a collection of common and uncommon clinical challenges with up-to-date obstetric anesthesia practices that serve both experienced and novice clinicians. Chapters include a brief review of the topic, clinical pearls, bullet points and tables highlighting key information, references for the latest scientific information and primary literature, as well as guides, protocols, or standard operating procedures for immediate application, all based on the BIDMC Department of Anesthesia’s long history of providing cutting edge care for pregnant women. The text also serves as a clinical reference guide and teaching tool. Obstetric Anesthesia: Quick References & Practical Guides: Describes tools and methods for caring for pregnant women in labor Includes the best scientific evidence and BIDMC’s Department of Anesthesia’s Obstetrical Division’s thoroughly tested institutional practices used for the care of pregnant women Incorporates clear, step-by-step instructions and up-to-date guidelines and standards Provides essential information in each chapter, followed by evidence-based best practices for the given topic“/li> Pairs succinct presentations with relevant and practical instructions for patient care to support emergency decision making, problem solving, and patient safety
There have been many significant microbiological, biochemical and technological advances made in the understanding and implementation of anaerobic digestion processes with respect to industrial and domestic wastewater treatment. Elucida tion of the mechanisms of anaerobic degradation has permitted a greater control over the biological parameters of waste conversion and the technical advances achieved have reduced the time and land area requirements and increased the cost-effectiveness and efficiency of the various processes presently in use. By product recovery in the form of utilisable methane gas has become increasingly feasible, while the development of new and superior anaerobic reactor designs with increased tolerance to toxic and shock loadings of concentrated effiuents has established a potential for treating many extremely recalcitrant industrial wastestreams. The major anaerobic bioreactor systems and their applications and limitations are examined here, together with microbiological and biochemical aspects of anaerobic wastewater treatment processes. London, June 1986 S. M. Stronach T. Rudd J. N. Lester v Table of Contents 1 The Biochemistry of Anaerobic Digestion 1 1. 1 Kinetics of Substrate Utilisation and Bacterial Growth 3 1. 1. 1 COD Fluxes and Mean Carbon Oxidation State 3 1. 1. 2 Bacterial Growth and Biokinetics 4 1. 1. 2. 1 Growth and Single Substrate Kinetics 4 1. 1. 2. 2 Multisubstrate Systems . 8 1. 2 Kinetics and Biochemistry of Hydrolysis 8 1. 3 Kinetics and Biochemistry of Fermentation and J1-0xidation . 11 1.
This book develops an original theory of agentive modality: the kind of modality that is distinctive to agents. The central thesis is that the idea of an option should be taken as primitive, and that other agentive notions – such as ability, skill, and free will – should be understood in terms of options. The main contributions of this book are twofold. First, it resolves many of the outstanding questions in the metaphysics and semantics of agentive modality. In doing so, it develops original accounts of topics that have been central to philosophy since Aristotle. It also contributes to a lively contemporary literature on these topics. Second, it articulates an austere and uncompromising form of compatibilism about free will, termed “simple compatibilism.” Simple compatibilism is so-called because it rejects both the reductive theses endorsed by traditional compatibilists and the sophisticated proposals of many contemporary compatibilists. Instead, it turns precisely on insisting that options are analytically simple. Arguments for incompatibilism are shown to rest on auxiliary principles that should, in light of the book’s general account of options, be rejected.
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