Boston Congregationalist ministers Charles Chauncy (1705-1787) and Jonathan Mayhew (1720-1766) were significant political as well as religious leaders in colonial and revolutionary New England. Scholars have often stressed their influence on major shifts in New England theology, and have also portrayed Mayhew as an influential preacher, whose works helped shape American revolutionary ideology, and Chauncy as an active leader of the patriot cause. Through a deeply contextualised re-examination of the two ministers as ‘men of their times’, Oakes offers a fresh, comparative interpretation of how their religious and political views changed and interacted over decades. The result is a thoroughly revised reading of Chauncy’s and Mayhew’s most innovative ideas. Conservative Revolutionaries unearths strongly traditionalist elements in their belief systems, focussing on their shared commitment to a dissenting worldview based on the ideals of their Protestant New England and British heritage. Oakes concludes with a provocative exploration of how their shifting theological and political positions may have helped redefine prevailing notions of human identity, capability, and destiny.
Comprehensive, easy to read, and clinically relevant, Bradley’s Neurology in Clinical Practice provides the most up-to-date information presented by a veritable "Who's Who" of clinical neuroscience. Its unique organization allows users to access content both by presenting symptom/sign and by specific disease entities—mirroring the way neurologists practice. A practical, straightforward style; templated organization; evidence-based references; and robust interactive content combine to make this an ideal, dynamic resource for both practicing neurologists and trainees. Authoritative, up-to-date guidance from Drs. Daroff, Jankovic, Mazziotta, and Pomeroy along with more than 150 expert contributors equips you to effectively diagnose and manage the full range of neurological disorders. Easy searches through an intuitive organization by both symptom and grouping of diseases mirrors the way you practice. The latest advances in clinical neurogenetics, brain perfusion techniques for cerebrovascular disease, the relationship between neurotrauma and neurodegenerative disease, management strategies for levodopa-related complications in movement disorders, progressive neuropsychiatric disorders arising from autoimmune encephalitis, and more keep you at the forefront of your field. Reorganized table of contents which includes new chapters on: Brain Death, Vegetative, and Minimally Conscious States; Deep Brain Stimulation; Sexual Dysfunction in Degenerative and Spinal Cord Disorders; Sports and Performance Concussion; Effects of Drug Abuse on the Nervous System; and Mechanisms of Neurodegenerative Disorders. Regular online updates reflect the latest information on the diagnosis and treatment of neurologic diseases based on the latest recommendations and methodologies. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
There have been a large number of basic research studies of noninvasive brain stimulation in Parkinson’s disease. Initial work focused on measuring: (1) the excitability of corticospinal output with threshold and input–output measures, and (2) the effectiveness of intracortical γ-aminobutyric acid (GABA)ergic inhibitory systems using short-interval intracortical inhibition (SICI), long-interval intracortical inhibition (LICI), and silent period measures. Early suggestions of increased excitability and reduced inhibition have been progressively modified. There are conflicting reports on changes in excitability, silent period, and LICI, and the more consistent reduction in SICI is now viewed as a superimposed excitation rather than a primary deficit in a GABAergic mechanism. A small number of studies have suggested that premovement increases in corticospinal excitability may be prolonged in Parkinson’s disease, consistent with the suggestion of slower buildup of the motor command to move; there are also modifications of interhemispheric connections in patients with mirror movements. Transcranial magnetic stimulation (TMS) has also been used to explore the involvement of motor cortex and cerebellum in resting and postural tremors by examining how readily they can be reset by single TMS pulses over each area. It can also probe the effects of deep brain stimulation of motor cortex excitability. Finally, new TMS techniques that examine synaptic plasticity in motor cortex have shown reduced excitability in patients off therapy which is restored when on therapy. Data are also emerging about the possible role of cortical plasticity in compensating for gradual loss of dopaminergic function prior to onset of clinical symptoms.
At last there is a lucid, well-written OB book, which covers key issues required in OB teaching, but which has a mind of its own. Students and faculty will recognize this is more than standard fare." - Bill Cooke, Manchester Business School
Dynamic Thinking: A Primer on Dynamic Field Theory introduces the reader to a new approach to understanding cognitive and neural dynamics using the concepts of Dynamic Field Theory (DFT). Dynamic Neural Fields are formalizations of how neural populations represent the continuous dimensions of perceptual features, movements, and cognitive decisions. The concepts of DFT establish links between brain and behavior, revealing ways in which models of brain function can be tested with both neural and behavioral measures. Thus, DFT bridges the gap between brain and behavior, between neuroscience and the behavioral sciences. The book provides systematic tutorials on the central concepts of DFT and their grounding in both dynamical systems theory and neurophysiology. The concrete mathematical implementation of these concepts is laid out, supported by hands-on exercises that make use of interactive simulators in MATLAB. The book also contains a large set of exemplary case studies in which the concepts and associated models are used to understand how elementary forms of embodied cognition emerge and develop.
A practical, dynamic resource for practicing neurologists, clinicians and trainees, Bradley and Daroff's Neurology in Clinical Practice, Eighth Edition, offers a straightforward style, evidence-based information, and robust interactive content supplemented by treatment algorithms and images to keep you up to date with all that's current in this fast-changing field. This two-volume set is ideal for daily reference, featuring a unique organization by presenting symptom/sign and by specific disease entities—allowing you to access content in ways that mirror how you practice. More than 150 expert contributors, led by Drs. Joseph Jankovic, John C. Mazziotta, Scott L. Pomeroy, and Nancy J. Newman, provide up-to-date guidance that equips you to effectively diagnose and manage the full range of neurological disorders. - Covers all aspects of today's neurology in an easy-to-read, clinically relevant manner. - Allows for easy searches through an intuitive organization by both symptom and grouping of diseases. - Features new and expanded content on movement disorders, genetic and immunologic disorders, tropical neurology, neuro-ophthalmology and neuro-otology, palliative care, pediatric neurology, and new and emerging therapies. - Offers even more detailed videos that depict how neurological disorders manifest, including EEG and seizures, deep brain stimulation for PD and tremor, sleep disorders, movement disorders, ocular oscillations, EMG evaluation, cranial neuropathies, and disorders of upper and lower motor neurons, as well as other neurologic signs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Parkinson's Disease in the Older Patient, Second Edition" has been fully revised, updated and expanded to include new treatments and entirely new chapters. This authoritative text is written by recognised national specialists in the field and provides accessible, easy-to-read information. The practical and versatile approach comprehensively covers all aspects of treatment, and although it focuses on the older patient, it is also highly relevant for younger patient groups with an emphasis on multidisciplinary assessment and management. Detailed information on the aetiology and pathogenesis of the condition, drug and surgical treatments, sleep disturbances, quality of life and careers is now included, along with the more prevalent older patient issues such as neuropsychiatric disturbances, speech and swallowing problems, balance and falls, and autonomic disturbances. The updates also include new advice on the management and services in primary care, linked to the recent NICE guidelines.With official endorsement from The Parkinson's Disease Academy of the British Geriatrics Society, this new edition is highly recommended for general practitioners, geriatricians, neurologists and psychiatrists. Physiotherapists, occupational therapists, speech therapists, dieticians, and psychologists will also find it invaluable. It is suitable for general and specialist nurses, and will be of great use to researchers with an interest in Parkinson's disease.
Boston Congregationalist ministers Charles Chauncy (1705-1787) and Jonathan Mayhew (1720-1766) were significant political as well as religious leaders in colonial and revolutionary New England. Scholars have often stressed their influence on major shifts in New England theology, and have also portrayed Mayhew as an influential preacher, whose works helped shape American revolutionary ideology, and Chauncy as an active leader of the patriot cause. Through a deeply contextualised re-examination of the two ministers as ‘men of their times’, Oakes offers a fresh, comparative interpretation of how their religious and political views changed and interacted over decades. The result is a thoroughly revised reading of Chauncy’s and Mayhew’s most innovative ideas. Conservative Revolutionaries unearths strongly traditionalist elements in their belief systems, focussing on their shared commitment to a dissenting worldview based on the ideals of their Protestant New England and British heritage. Oakes concludes with a provocative exploration of how their shifting theological and political positions may have helped redefine prevailing notions of human identity, capability, and destiny.
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