John R. Helliwell's Books

The Whats of a Scientific Life

By: John R. Helliwell

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The Whats of a Scientific Life

By: John R. Helliwell

This book completes a scientific life trilogy of books following on from the Hows (i.e. skills) and the Whys is now the Whats of a scientific life. Starting with just what is science, then on to what is physics, what is chemistry and what is biology the book discusses career situations in terms of types of obstacles faced. There follow examples of what science has achieved as well as plans and opportunities. The contexts for science are dependencies of science on mathematics, how science cuts across disciplines, and the importance of engineering and computer software. What science is as a process is that it is distinctly successful in avoiding or dealing with failures. Most recently a radical change in what is science is the merger of the International Council of Scientific Unions and the International Social Sciences Council. Key Features: Dissects what is science and its contexts Provides wide ranging case studies of science and discovery based directly on the author’s many decades in science The author has outstanding experience in mentoring and career development, and also in outreach activities for the public and students of all ages The world of science today involves a merger of ‘the sciences’ and the ‘social sciences’

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Page Count

137

Publisher

CRC Press

Published Date

ISBN 10

1000731235

ISBN 13

9781000731231

Perspectives in Crystallography

By: John R. Helliwell

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Perspectives in Crystallography

By: John R. Helliwell

Crystallography is one of the most multidisciplinary sciences, with roots in fields as varied as mathematics, physics, chemistry, biology, materials science, computation and earth and planetary science. The structural knowledge gained from crystallography has been instrumental in acquiring new levels of understanding in numerous scientific areas. P

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Page Count

176

Publisher

CRC Press

Published Date

ISBN 10

1498732119

ISBN 13

9781498732116

Macromolecular Crystallography with Synchrotron Radiation

By: John R. Helliwell

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Macromolecular Crystallography with Synchrotron Radiation

By: John R. Helliwell

This highly illustrated monograph provides a comprehensive treatment of the study of the structure and function of the molecules of life--proteins, nucleic acids, and viruses--using synchrotron radiation and crystallography. Beginning with chapters on the fundamentals of macromolecular crystallography and macromolecular structure, the book goes on to review the sources and properties of synchrotron radiation, instrumentation, and monochromatic data collection. There are also chapters on the Laue method, on diffuse X-ray scattering, and on variable wavelength anomalous dispersion methods. The book concludes with a description and survey of applications including studies at high resolution, the use of small crystals, the study of large unit cells, and time-resolved crystallography (particularly of enzymes). Appendices are provided that present essential information for the synchrotron user as well as information about synchrotron facilities currently available.

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Page Count

620

Publisher

Cambridge University Press

Published Date

ISBN 10

0521544041

ISBN 13

9780521544047

The Whens and Wheres of a Scientific Life

By: John R. Helliwell

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The Whens and Wheres of a Scientific Life

By: John R. Helliwell

Big questions and issues arise about the role of the scientific life in our society and in our world. These have to do with trusting science at all, or with the wider roles of the scientist. The Whens and Wheres of a Scientific Life serves as an epilogue to author John R. Helliwell’s scientific life trilogy of books on the Hows (i.e. skills), the Whys and the Whats of a scientific life. When and where questions play a big role in major science facility decisions. When and where also play a big role in controlling a pandemic like the coronavirus COVID-19. The consequences of such work and the role science plays in society are discussed in this book. Key Features: Discusses when and where we can make new and better things happen and make new discoveries. Explains whens and wheres as examples in basic science and explaining these to the public User friendly and concise, this text provides a wide range of examples of science and discovery The author has diverse experience in career development, teaching and research The importance of open data to the reproducibility of science are described

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Page Count

158

Publisher

CRC Press

Published Date

ISBN 10

1000344045

ISBN 13

9781000344042

Macromolecular Crystallization and Crystal Perfection

By: Naomi E Chayen,John R Helliwell,Edward H Snell

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Macromolecular Crystallization and Crystal Perfection

By: Naomi E Chayen,John R Helliwell,Edward H Snell

The crystallization of proteins and nucleic acids and/or their complexes has become more highly automated but is still often a trial and error based approach. In parallel, a number of X-ray diffraction based techniques have been developed which explain the physical reasons limiting the resulting crystallographic data and thus show how that data may be improved. Crystal growth is also pivotal in neutron crystallography, which establishes the hydrogen and hydration aspects. Thus this book is aimed at addressing the science behind obtaining the best and most complete structural data possible for biological macromolecules, so that the detailed structural biology and chemistry of these important molecules emerge. Crystal imperfections such as twinning and lattice disorders, as well as multiple crystal situations, and their possible remedies, are also described. The small crystal frontier in micro-crystal crystallography, crystallites in powders and finally down to the proposed single molecule structure determination of X-ray lasers are covered. Overall this interdisciplinary book will interest crystal growers, X-ray and neutron physicists and the biological crystallographers, including graduate students.

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Page Count

240

Publisher

OUP Oxford

Published Date

ISBN 10

0191550027

ISBN 13

9780191550027

The Scientific Truth, the Whole Truth and Nothing but the Truth

By: John R. Helliwell

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The Scientific Truth, the Whole Truth and Nothing but the Truth

By: John R. Helliwell

There is a limited understanding amongst scientists, students, and the public about realizing trust in scientific findings. This should be a paramount objective. Scientists and the public need to know more about the link between the philosophy of science and science research methods. There is a limited understanding of why accuracy is important and that it is not the same as precision. Also, there is often the need to be pragmatic and so measure an approximation of a real system, and the classic case is reductionism in biology versus whole organism biology. The author brings these topics together in terms of trusting in science. Features Covers how scientific truth is perceived and increases the preparedness of early career scientists. Examines the relatively new field of machine learning and artificial intelligence as applied to crystallography databases in biology and chemistry for new discoveries. Describes the major changes in digital data archiving and how vast “raw data” archives are being increasingly developed for machine learning and artificial intelligence as well as complete truth. This unique volume will be of interest to pre-university and university undergraduate students, principally in science. Presents scientific research examples from physics, chemistry, and biology together with their methodologies.

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Page Count

107

Publisher

CRC Press

Published Date

ISBN 10

1040003788

ISBN 13

9781040003787

Skills for a Scientific Life

By: John R. Helliwell

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Skills for a Scientific Life

By: John R. Helliwell

Being, or wanting to become, a scientist requires academic training in the science subjects. To succeed as a research scientist and educator requires specific as well as general skills. Skills for a Scientific Life provides insight into how to be successful. This career book is intended for potential entrants, early career and mid-career scientists for a wide range of science disciplines. Features Offers advice on specific skills for research article writing, grant writing, and refereeing as well as teaching undergraduates and supervising postgraduates Provides helpful case studies resulting from the author's teaching and mentoring experience Contributes a special emphasis on skills for realizing wider impacts such as sustainability and gender equality Presents several chapters on leadership skills both in academe and in government service Concludes with an emphasis on the author’s overall underpinning of the topics from the point of view of ethics

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Page Count

197

Publisher

CRC Press

Published Date

ISBN 10

1315394413

ISBN 13

9781315394411

The Whys of a Scientific Life

By: John R. Helliwell

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The Whys of a Scientific Life

By: John R. Helliwell

User friendly and concise, this text dissects the whys of science and discovery The author has outstanding experience in mentoring science students and staff, and also in outreach activities for the public and students of all ages including schools The final chapter emphasises the joys of the scientist in research

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