A critically important book that forces us to ask new questions about the synthetic chemicals that we have spread across this earth."—former vice president Al Gore, author of An Inconvenient Truth Our Stolen Future examines the ways that certain synthetic chemicals interfere with hormonal messages involved in the control of growth and development, especially in the fetus. The developing fetus uses these natural hormonal messages, which come from both from its own hormone system and from its mother, to guide development. They influence virtually all of the growing individual's characteristics, from determining its sex to controlling the numbers of toes and fingers to shaping intricate details of brain structure. Scientific research over the last 50 years has revealed that this hormonal control of development is vulnerable to disruption by synthetic chemicals. Through a variety of mechanisms, hormone-disrupting chemicals (also known as endocrine disrupting chemicals or endocrine disruptors) interfere with the natural messages and alter the course of development, with potential effects on virtually all aspects of bodily function. Our Stolen Future explores the scientific discovery of endocrine disruption. The investigation begins with wildlife, as it was in animals that the first hints of widespread endocrine disruption appeared. The book then examines a series of experiments examining endocrine disruption of animals in the laboratory which show conclusively that fetal exposure to endocrine disrupting chemicals can wreak life-long damage. These experiments also reveal some of the biological processes by which these chemicals have their effects, and that endocrine disruption effects can be caused by exposure to infinitesimally small amounts of contaminant. Moving from animals to people, Our Stolen Future summarizes a series of well-studied examples where people have been affected by endocrine disrupting chemicals, most notably the synthetic hormone dietheylstilbestrol (DES), to which several million women were exposed through misguided medical attempts to manage difficult pregnancies in the 1950s, '60s and '70s. Our Stolen Future then asks a broader, more difficult and more controversial set of questions. Given what is known from wildlife and laboratory studies, and from examples of well-studied human exposure, and given that exposure to endocrine disrupting chemicals in the real world is widespread at levels comparable to those sufficient to cause animal harm, what effects should health scientists be looking for in people in general? Effects to be expected include declines in fertility and other impacts on the reproductive system of both men and women, impairments in disease resistance, and erosions in intelligence.
A critically important book that forces us to ask new questions about the synthetic chemicals that we have spread across this earth."—former vice president Al Gore, author of An Inconvenient Truth Our Stolen Future examines the ways that certain synthetic chemicals interfere with hormonal messages involved in the control of growth and development, especially in the fetus. The developing fetus uses these natural hormonal messages, which come from both from its own hormone system and from its mother, to guide development. They influence virtually all of the growing individual's characteristics, from determining its sex to controlling the numbers of toes and fingers to shaping intricate details of brain structure. Scientific research over the last 50 years has revealed that this hormonal control of development is vulnerable to disruption by synthetic chemicals. Through a variety of mechanisms, hormone-disrupting chemicals (also known as endocrine disrupting chemicals or endocrine disruptors) interfere with the natural messages and alter the course of development, with potential effects on virtually all aspects of bodily function. Our Stolen Future explores the scientific discovery of endocrine disruption. The investigation begins with wildlife, as it was in animals that the first hints of widespread endocrine disruption appeared. The book then examines a series of experiments examining endocrine disruption of animals in the laboratory which show conclusively that fetal exposure to endocrine disrupting chemicals can wreak life-long damage. These experiments also reveal some of the biological processes by which these chemicals have their effects, and that endocrine disruption effects can be caused by exposure to infinitesimally small amounts of contaminant. Moving from animals to people, Our Stolen Future summarizes a series of well-studied examples where people have been affected by endocrine disrupting chemicals, most notably the synthetic hormone dietheylstilbestrol (DES), to which several million women were exposed through misguided medical attempts to manage difficult pregnancies in the 1950s, '60s and '70s. Our Stolen Future then asks a broader, more difficult and more controversial set of questions. Given what is known from wildlife and laboratory studies, and from examples of well-studied human exposure, and given that exposure to endocrine disrupting chemicals in the real world is widespread at levels comparable to those sufficient to cause animal harm, what effects should health scientists be looking for in people in general? Effects to be expected include declines in fertility and other impacts on the reproductive system of both men and women, impairments in disease resistance, and erosions in intelligence.
Since the dawn of the industrial age, we have unleashed a bewildering number of potentially harmful chemicals. But out of this vast array, how do we identify the actual threats? What does it take to prove that a certain chemical causes cancer? How do we translate academic knowledge of the toxic effects of particular substances into understanding real-world health consequences? The science that answers these questions is toxicology. In The Alchemy of Disease, John Whysner offers an accessible and compelling history of toxicology and its key findings. He details the experiments and discoveries that revealed the causal connections between chemical exposures and diseases. Balancing clear accounts of groundbreaking science with human drama and public-policy relevance, Whysner describes key moments in the development of toxicology and their thorny social and political implications. The book features discussions of toxicological problems past and present, including DDT, cigarettes and other carcinogens, lead poisoning, fossil fuels, chemical warfare, pharmaceuticals—including opioids—and the efficacy of animal testing. Offering valuable insight into the science and politics of crucial public-health concerns, The Alchemy of Disease shows that toxicology’s task—pinpointing the chemical cause of an illness—is as compelling as any detective story.
When first published in 2009, Nature’s Matrix set out a radical new approach to the conservation of biodiversity. This new edition pushes the frontier of the biodiversity/agriculture debate further, making an even stronger case for the need to transform agriculture and support small- and medium-scale agroecology and food sovereignty. In the first edition, the authors set out a radical new approach to the conservation of biodiversity. This is based on the concept of a landscape as a matrix of diverse, small-scale agricultural ecosystems, providing opportunities to enhance conservation under the stewardship of local farmers. This contrasts with the alternative view of industrial-scale farms and large protected areas which exclude local people. However, since then the debate around conservation and agriculture has developed significantly and this is reflected in this updated second edition. The text is thoroughly revised, including: a reorganization of chapters with new and timely topics introduced, updates to the discussion of agroecology and food sovereignty, bringing it in line with the current debates, greater coverage of the role of agroecology, in particular agroforestry, as an important component of climate change adaptation and mitigation, highlighting recent studies on the role of intensive agriculture in climate change and loss of biodiversity, and more attention given to the discussion of land sparing versus land sharing. By integrating the ecological aspects of agriculture and conservation biology, with a political and social analysis as well as historical perspective, the book continues to set a progressive agenda and appeals to a wide range of students and professionals.
This critical, state-of-the-art review brings together the scattered and often controversial information on multidrug resistance reversal. Leading scientists in the field cover P-glycoprotein, the genetics of resistance, and its reversal by drugs. Resistance modifiers and modulators are tabulated and critically evaluated. Reversal of Multidrug Resistance in Cancer is important reading for oncologists, cancer chemotherapists, and other cancer researchers.
- NEW chapters cover the most important, emerging information on current diagnostic, treatment, and preventive challenges in today's veterinary practice. - A new section on feline and canine nutrition covers important issues in nutritional health. - 50 new chapter authors join hundreds of expert international contributors, all of whom are leading authorities in their fields. - NEW! Availability as Pageburst ebook allows you digital access to this volume along with your library of other Elsevier references.
Psychology is of interest to academics from many fields, as well as to the thousands of academic and clinical psychologists and general public who can't help but be interested in learning more about why humans think and behave as they do. This award-winning twelve-volume reference covers every aspect of the ever-fascinating discipline of psychology and represents the most current knowledge in the field. This ten-year revision now covers discoveries based in neuroscience, clinical psychology's new interest in evidence-based practice and mindfulness, and new findings in social, developmental, and forensic psychology.
This book provides a collection of key methodological writings in mixed methods research along with a collection of exemplar studies. This cross-disciplinary volume helps define the "literature" of mixed methods research. Selections are draw from the international literature that has appeared across diverse research disciplines over the past 30 years. Key features: writings in the field of mixed methods: methodological selections address research design types and purposes, data collection, data analysis, reporting, and future directions; offers exemplar research studies: examples include published studies from diverse disciplines, including sociology, education, evaluation, health sciences, nursing, and family science; Provides visual diagrams to illustrate exemplar research studies: these diagrams help readers understand how the method's components are implemented and how they can develop diagrams for their own studies.
Cherie Calbom, "The Juice Lady," therapist John Calbom, and Michael Mahaffey, a twenty-year cancer survivor, present a unique, multi-disciplinary approach to fighting cancer.
The grim history of Nauru Island, a small speck in the Pacific Ocean halfway between Hawaii and Australia, represents a larger story of environmental degradation and economic dysfunction. For more than 2,000 years traditional Nauruans, isolated from the rest of the world, lived in social and ecological stability. But in 1900 the discovery of phosphate, an absolute requirement for agriculture, catapulted Nauru into the world market. Colonial imperialists who occupied Nauru and mined it for its lucrative phosphate resources devastated the island, which forever changed its native people. In 1968 Nauruans regained rule of their island and immediately faced a conundrum: to pursue a sustainable future that would protect their truly valuable natural resources—the biological and physical integrity of their island—or to mine and sell the remaining forty-year supply of phosphate and in the process make most of their home useless. They did the latter. In a captivating and moving style, the authors describe how the island became one of the richest nations in the world and how its citizens acquired all the ills of modern life: obesity, diabetes, heart disease, hypertension. At the same time, Nauru became 80 percent mined-out ruins that contain severely impoverished biological communities of little value in supporting human habitation. This sad tale highlights the dire consequences of a free-market economy, a system in direct conflict with sustaining the environment. In presenting evidence for the current mass extinction, the authors argue that we cannot expect to preserve biodiversity or support sustainable habitation, because our economic operating principles are incompatible with these activities.
Animal Learning and Cognition: An Introduction provides an up-to-date review of the principal findings from more than a century of research into animal intelligence. This new edition has been expanded to take account of the many exciting developments that have occurred over the last ten years. The book opens with a historical survey of the methods that have been used to study animal intelligence, and follows by summarizing the contribution made by learning processes to intelligent behavior. Topics include Pavlovian and instrumental conditioning, discrimination learning, and categorization. The remainder of the book focuses on animal cognition and covers such topics as memory, navigation, social learning, language and communication, and knowledge representation. Expanded areas include extinction (to which an entire chapter is now devoted), navigation in insects, episodic memory in birds, imitation in birds and primates, and the debate about whether primates are aware of mental states in themselves and others. Issues raised throughout the book are reviewed in a concluding chapter that examines how intelligence is distributed throughout the animal kingdom. The broad spectrum of topics covered in this book ensures that it will be of interest to students of psychology, biology, zoology, and neuroscience. Since very little background knowledge is required, the book will be of equal value to anyone simply interested in either animal intelligence, or the animal origins of human intelligence. This textbook is accompanied by online instructor resources which are free of charge to departments who adopt this book as their text. They include chapter-by-chapter lecture slides, an interactive chapter-by-chapter multiple-choice question test bank, and multiple-choice questions in paper and pen format.
Counseling older adults is not equivalent to counseling the general population, and specialized skills and knowledge, as well as sensitivity to the contexts in which older adults live, are essential in working successfully with this population. This text provides an introduction to gerontological counseling, integrating the basic skills of working with older adults with theories of counseling and aging. Specific counseling issues discussed include mental health counseling, career counseling, rehabilitation counseling, and family counseling. Along with these, important contextual factors such as race/culture, social class, social justice, spirituality, Alzheimer’s and other dementias, and family issues are considered in light of the latest research. Each chapter contains case studies, discussion questions, a glossary, and suggestions for further reading to reinforce the material presented.
The Natural Way for Landscape Architects and Contractors, Commercial Growers, Golf Course Managers, Park Administrators, Turf Managers, and Other Stewards of the Land
The Natural Way for Landscape Architects and Contractors, Commercial Growers, Golf Course Managers, Park Administrators, Turf Managers, and Other Stewards of the Land
A handbook for organic landscaping and turf management for recreational and commercial properties, public spaces, parks and urban gardens. Can you manage the landscape of a golf course, city park, or corporate campus without synthetic fertilizers and toxic pesticides? Absolutely! Organic landscaping is not only possible on a large scale, but it also makes sense both economically and environmentally. It promotes healthy soils and plants, which require less water and sequester more carbon—a winning combination for both your bottom line and the planet’s fight against resource depletion and global warming. Organic programs on a commercial scale have enormous potential to make a difference in the quality of our environment, our use of fuels, and climate change. And as those who have already converted to organics have discovered, they also cost a lot less over the long term. Organic Management for the Professional is the first comprehensive guide to “going green” in large-scale landscaping. Nationally recognized organic gardening expert Howard Garrett, with associates John Ferguson and Mike Amaranthus, not only explains in detail how to manage projects with natural organic techniques, but also presents the material in clear, simple terms so that commercial and institutional property owners can understand what to ask of their landscape architects, contractors, growers, and maintenance people. They give detailed, proven instructions for the key components of organic landscaping—soil building, correct planting techniques, fertilizing, pest control, compost, and mulch. Then they show how to apply these organic methods in large-scale landscaping, commercial growing, such as orchards, tree farms, nurseries, and greenhouse operations, and recreational properties such as sports fields and parks.
High gas prices aren’t the end of the world- but they may be the beginning of the end. This, at least, is the feeling of many who shudder at the staggering power oil-rich countries have over the world’s political affairs. In Petrotyranny, John Bacher uncovers the frightening facts of the world’s oil industry. He reveals that the worst dictatorships control six times the reserves that are under democratic control, and explores the potential for global conflict that exists as the demand for energy increases and the oil supply decreases. What kind of power will these dictatorships possess in the future? How many wars will be fought over the ever-shrinking supply of oil? Bacher takes an optimistic approach, viewing the problem as a challenge: the world’s democracies need to devise a creative response to avoid the looming crisis. That is, start replacing fossil-fuel burning with renewable energy - and start the process now.
The present is more than a place where the past comes to rest. It is more than a staging ground for the future. The present is where God shows up. We live our lives in the present, but often our minds are racing toward the future or overwhelmed by the past. We want to change the past and control the future, but usually all we really do is exhaust ourselves in the here and now. Writing especially with church leaders in mind, Dr. John Koessler, a former pastor and professor, teaches you how to evade the tyranny of past regrets and future plans and meet God right where you are, in the present.
The pedosphere - the thin mantel of soil on the earth's surface - plays a potentially crucial role in climate and climate change . The carbon storage of soils is the second largest in the biosphere, making the dynamics of soil organic carbon an important issue that must be understood if we are to fully comprehend global change. This new book examines the importance of soils and their relationship to global change, specifically to the greenhouse effect. Soils and Global Change presents a state-of-the-art compendium of our present knowledge of soils. This up-to-date information source enables readers to delve into the literature about soils and climate change and examine soils in both natural and managed environments.
We live in a world awash in manmade chemicals, from the pesticides on our front lawns to the diesel exhaust in the air we breathe. Although experts are beginning to understand the potential dangers of these substances, there are still more than 80,000 synthetic compounds that have not been sufficiently tested to interpret their effects on human health. Yale University professor John Wargo has spent much of his career researching the impact of chemical exposures on women and children. In this book, he explains the origins of society’s profound misunderstanding of everyday chemical hazards and offers a practical path toward developing greater “green intelligence.” Despite the rising trend in environmental awareness, information about synthetic substances is often unavailable, distorted, kept secret, or presented in a way that prevents citizens from acting to reduce threats to their health and the environment. By examining the histories of five hazardous technologies and practices, Wargo finds remarkable patterns in the delayed discovery of dangers and explains the governments’ failures to manage them effectively. Sobering yet eminently readable, Wargo’s book ultimately offers a clear vision for a safer future through prevention, transparency, and awareness.
The concise yet authoritative presentation of key techniques for basic mixtures experiments Inspired by the author's bestselling advanced book on the topic, A Primer on Experiments with Mixtures provides an introductory presentation of the key principles behind experimenting with mixtures. Outlining useful techniques through an applied approach with examples from real research situations, the book supplies a comprehensive discussion of how to design and set up basic mixture experiments, then analyze the data and draw inferences from results. Drawing from his extensive experience teaching the topic at various levels, the author presents the mixture experiments in an easy-to-follow manner that is void of unnecessary formulas and theory. Succinct presentations explore key methods and techniques for carrying out basic mixture experiments, including: Designs and models for exploring the entire simplex factor space, with coverage of simplex-lattice and simplex-centroid designs, canonical polynomials, the plotting of individual residuals, and axial designs Multiple constraints on the component proportions in the form of lower and/or upper bounds, introducing L-Pseudocomponents, multicomponent constraints, and multiple lattice designs for major and minor component classifications Techniques for analyzing mixture data such as model reduction and screening components, as well as additional topics such as measuring the leverage of certain design points Models containing ratios of the components, Cox's mixture polynomials, and the fitting of a slack variable model A review of least squares and the analysis of variance for fitting data Each chapter concludes with a summary and appendices with details on the technical aspects of the material. Throughout the book, exercise sets with selected answers allow readers to test their comprehension of the material, and References and Recommended Reading sections outline further resources for study of the presented topics. A Primer on Experiments with Mixtures is an excellent book for one-semester courses on mixture designs and can also serve as a supplement for design of experiments courses at the upper-undergraduate and graduate levels. It is also a suitable reference for practitioners and researchers who have an interest in experiments with mixtures and would like to learn more about the related mixture designs and models.
While jury decision making has received considerable attention from social scientists, there have been few efforts to systematically pull together all the pieces of this research. In Jury Decision Making, Dennis J. Devine examines over 50 years of research on juries and offers a "big picture" overview of the field. The volume summarizes existing theories of jury decision making and identifies what we have learned about jury behavior, including the effects of specific courtroom practices, the nature of the trial, the characteristics of the participants, and the evidence itself. Making use of those foundations, Devine offers a new integrated theory of jury decision making that addresses both individual jurors and juries as a whole and discusses its ramifications for the courts. Providing a unique combination of broad scope, extensive coverage of the empirical research conducted over the last half century, and theory advancement, this accessible and engaging volume offers "one-stop shopping" for scholars, students, legal professionals, and those who simply wish to better understand how well the jury system works.
Few American towns went untouched by World War II, even those in remote corners of the country. During that era, the federal government forever changed the lives of many northern Arizona citizens with the construction of the U.S. Army ordnance depot at Bellemont, ten miles west of Flagstaff. John Westerlund now tells how this linchpin in the war effort marked a turning point in Flagstaff's history. One of only sixteen munitions depots built between 1941 and 1943, the Navajo Ordnance Depot contributed significantly to the city's rapid growth during the war years as it brought considerable social, cultural, and economic change to the region. A clearing in the ponderosa pine forest called Volunteer Prairie met the military's criteria for a munitions depot—open terrain, a cool climate, plentiful water, and proximity to a railroad—and it was also sufficiently inland to be safe from the threat of coastal invasion. Constructing a depot of 800 ammunition bunkers, each the size of a 2,000-square-foot home, called for a force of 8,000 laborers, and Flagstaff became a boom town overnight as construction workers and their families poured in from nearby Indian reservations and as far away as the Midwest and South. More than 2,000 were retained as permanent employees—a larger workforce than Flagstaff's total pre-war employment roster. As Westerlund's portrait of wartime Flagstaff shows, prosperity brought unanticipated consequences: racism simmered beneath the surface of the town as ethnic groups were thrown together for the first time; merchants called a city-wide strike to protest emerging union activity; juvenile delinquency rose dramatically; Flagstaff women entered the workforce in unprecedented numbers, altering local mores along with their own plans for the future; meanwhile, hundreds of sailors and marines arrived at Arizona State Teachers College to participate in the Navy's "V-12" program. Whether recounting the difficulty of 3,500 Navajo and Hopi employees adjusting to life off the reservation or the complaints of townspeople that Austrian POWs-transferred to the depot to ease the labor shortage-were treated too well, Westerlund shows that the construction and maintenance of the facility was far more than a military matter. Navajo Ordnance Depot remained operational to support wars in Korea, Vietnam, and the Persian Gulf, and today Camp Navajo provides storage for thousands of deactivated ICBM motors. But in recounting its early days, Westerlund has skillfully blended social and military history to vividly portray not only a city's transitional years but also the impact of military expansion on economic and community development in the American West.
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