Advances in analytical chemistry methodology now allow us to detect the most minute trace amounts of pesticides. As this capacity grows, so does public concern about toxic contamination, resulting in stricter government regulations and a growing demand for even more sensitive, precise, and reliable analysis. Addressing the interplay between regulations and the development of analytical technology, this volume presents the first unified treatment of the regulatory and analytical aspects of pesticide residues. Current regulations, existing and emerging methodologies, state-of-the-art instrumentation, and the basic science of analyzing for pesticides in food and other environmental media are all covered. The book provides step-by-step guidelines to analytical techniques, along with real-world examples from the latest research-showing the reader how to analyze minute traces of pesticides quickly and accurately, using both highly sophisticated and basic, less sensitive techniques. Many safety issues are explored in depth, as are the regulatory aspects of pesticide registration, residue analysis, exposure monitoring, risk assessment, and tolerance enforcement. Timely, authoritative, and practical throughout, Pesticide Residues in Foods is an invaluable reference for analytical chemists and laboratory managers everywhere-in industry, agriculture, environmental sciences, research, and instrument manufacturing-and for anyone with an interest in the broader environmental, agricultural, and consumer-related implications of pesticide use. An invaluable resource for analytical chemists and laboratory managers, Pesticide Residues in Foods provides a complete overview of the theory, practice, and regulatory aspects of pesticide residue analysis today, including: * All regulatory issues, from risk assessment and tolerance to data-quality requirements to laboratory accreditation standards * State-of-the-art methodologies and instrumentation, including high- performance liquid chromatography and mass spectrometry * The application of analytical technology to "green chemistry," such as the reduction of solvents and toxic reagents in the laboratory * Novel solutions to the old problem of keeping the food supply safe from harmful levels of pesticides * Ample examples to help analytical chemists select the most appropriate method for a given residue analysis * Easy-to-use tables and figures throughout the text
The first edition of Integrated Methods for Optimization was published in January 2007. Because the book covers a rapidly developing field, the time is right for a second edition. The book provides a unified treatment of optimization methods. It brings ideas from mathematical programming (MP), constraint programming (CP), and global optimization (GO)into a single volume. There is no reason these must be learned as separate fields, as they normally are, and there are three reasons they should be studied together. (1) There is much in common among them intellectually, and to a large degree they can be understood as special cases of a single underlying solution technology. (2) A growing literature reports how they can be profitably integrated to formulate and solve a wide range of problems. (3) Several software packages now incorporate techniques from two or more of these fields. The book provides a unique resource for graduate students and practitioners who want a well-rounded background in optimization methods within a single course of study. Engineering students are a particularly large potential audience, because engineering optimization problems often benefit from a combined approach—particularly where design, scheduling, or logistics are involved. The text is also of value to those studying operations research, because their educational programs rarely cover CP, and to those studying computer science and artificial intelligence (AI), because their curric ula typically omit MP and GO. The text is also useful for practitioners in any of these areas who want to learn about another, because it provides a more concise and accessible treatment than other texts. The book can cover so wide a range of material because it focuses on ideas that arerelevant to the methods used in general-purpose optimization and constraint solvers. The book focuses on ideas behind the methods that have proved useful in general-purpose optimization and constraint solvers, as well as integrated solvers of the present and foreseeable future. The second edition updates results in this area and includes several major new topics: Background material in linear, nonlinear, and dynamic programming. Network flow theory, due to its importance in filtering algorithms. A chapter on generalized duality theory that more explicitly develops a unifying primal-dual algorithmic structure for optimization methods. An extensive survey of search methods from both MP and AI, using the primal-dual framework as an organizing principle. Coverage of several additional global constraints used in CP solvers. The book continues to focus on exact as opposed to heuristic methods. It is possible to bring heuristic methods into the unifying scheme described in the book, and the new edition will retain the brief discussion of how this might be done.
This expanded and updated edition of Legal Issues in Child Abuse and Neglect Practice will familiarize professionals from medicine, nursing, psychology, social work, and related disciplines with the innumerable legal implications in their day-to-day work. Offering a state-of-the-art exploration of the role that law can play in cases of child maltreatment, this edition closes the communication gap between legal and helping professionals that sometimes reduces efficacy and cooperation in achieving the common goal of improving the lives of victimized children. This new edition continues to provide vital information to non-lawyers regarding how the legal system works in child maltreatment cases. John E. B. Myers discusses the prevalence and effects of child maltreatment, and he outlines the child protection system with clarity. Other areas covered include the investigation and reporting laws, issues of confidentiality and disclosure, expert testimony, cross examination and impeachment, and the liability of professionals. Legal Issues in Child Abuse and Neglect Practice is a must-read for mental health and legal professionals, health care providers, educators, and child advocates. Advanced clinical and legal students as well as academics and researchers will also find this material essential.
During the last century, nuclear power has been established as a reliable source of energy in the major industrialised countries. It has recently enjoyed a revival in attention and research due to the environmental concerns surrounding current conventional energy sources. Issues of regulation and safety are at the forefront of all discussions involving nuclear power, and will govern its place in the future. The Future of Nuclear Power takes a technical and comprehensive look at the current and future status of nuclear power throughout the world. The 17 chapters are divided into two main sections: a review of all current generation plants, and concepts for new advanced reactor design and safety. The broad-ranging topics covered by this publication, coupled with the current revival of interest in nuclear energy, make it a timely reference for all nuclear scientists. Reviews the issues surrounding the future operation of existing commercial nuclear plants Several chapters dedicated to the extensive research programs in place concerning safe and reliable operation Compares nuclear and non-nuclear options for energy needs in the future; evaluating the benefits and risks of both
Material handling and logistics have become especially important to industrialists because of the competitive advantage that results from using the right methods to provide the right amount of the right material at the right place, at the right time, in the right condition, in the right sequence, in the right orientation, and at the right cost. But, what are the right methods? The emergence of sophisticated control systems, coupled with advances in hardware design, has resulted in a wide variety oftechno logical alternatives availablefor practically any application. Yet, with the emergence of just-in-time methods and the apparent success of the firms that have relied on the use of people and" simple" rules, rather than technology, the proper role of hardware and software in material handling and logistics is open to debate. Despite all that has been accomplished to date, the design of material handling and logistics systems remains an art as well as a science. Regardless of whether it is people, conveyors, lift trucks, robots, guided vehicles, laser scanners, storage/retrieval machines, carousels, voice encoding, machine vision, automatic palletizers, or other methods that are appropriate, selecting the right methods for moving, storing, and controlling material is vital. It is important that the selection decision be made after consideration is given to the requirements for amount, material, place, time, condition, sequence, orientation, and cost.
Polycyclische aromatische Kohlenwasserstoffe (PAHs) gehören zu den ersten Chemikalien, die als krebserregend für den Menschen erkannt wurden. Erstmals werden in diesem Buch PAHs mit mehr als sieben Ringen auf modernem Stand systematisch abgehandelt. Spezielle Kapitel beschäftigen sich mit Probenvorbereitung und -handling; auch ein Vergleich verschiedener Analyseverfahren ist enthalten. Besonders nützlich für den Laboralltag ist ein ausführlicher Anhang mit Strukturformeln sowie UV-Absorptions- und Fluoreszenz-Emissionsspektren von fast 50 Verbindungen.
A definitive reference, completely updated Published in 1989, the First Edition of this book, originally entitled Quadrupole Storage Mass Spectrometry, quickly became the definitive reference in analytical laboratories worldwide. Revised to reflect scientific and technological advances and new applications in the field, the Second Edition includes new chapters covering: * New ion trap instruments of high sensitivity * Peptide analysis by liquid chromatography/ion trap tandem mass spectrometry * Analytical aspects of ion trap mass spectrometry combined with gas chromatography * Simulation of ion trajectories in the ion trap One additional chapter discusses the Rosetta mission, a "comet chaser" that was sent on a ten-year journey in 2004 to study the comet Churyumov-Gerasimenko using, among other instruments, a GC/MS system incorporating a specially designed ion trap mass spectrometer. This comprehensive reference also includes discussions of the history of the quadrupole ion trap, the theory of quadrupole mass spectrometry, the dynamics of ion-trapping chemistry in the quadrupole ion trap, the cylindrical ion trap, miniature traps, and linear ion traps. Complete with conclusions and references, this primer effectively encapsulates the body of knowledge on quadrupole ion trap mass spectrometry. With its concise descriptions of the theory of ion motion and the principles of operation, Quadrupole Ion Trap Mass Spectrometry, Second Edition is ideal for new users of quadrupole devices, as well as for scientists, researchers, and graduate and post-doctoral students working in analytical laboratories.
This new work covers the highly sensitive topic of who polices the police. Dealing with all aspects of the law relating to the regulation of the police, it gives detailed analysis and guidance on practice at complaints and misconduct hearings and the role and powers of the IPCC and of its statutory guidance. Appendices include regulations and associated Home Office Guidance under the 2004 and 2008 performance and misconductregimes, and the new 2008 PAT rules.
The definitive guide to the knowledge and skills necessary to practice Hospital Medicine Presented in full color and enhanced by more than 700 illustrations, this authoritative text provides a background in all the important clinical, organizational, and administrative areas now required for the practice of hospital medicine. The goal of the book is provide trainees, junior and senior clinicians, and other professionals with a comprehensive resource that they can use to improve care processes and performance in the hospitals that serve their communities. Each chapter opens with boxed Key Clinical Questions that are addressed in the text and hundreds of tables encapsulate important information. Case studies demonstrate how to apply the concepts covered in the text directly to the hospitalized patient. Principles and Practice of Hospital Medicine is divided into six parts: Systems of Care: Introduces key issues in Hospital Medicine, patient safety, quality improvement, leadership and practice management, professionalism and medical ethics, medical legal issues and risk management, teaching and development. Medical Consultation and Co-Management: Reviews core tenets of medical consultation, preoperative assessment and management of post-operative medical problems. Clinical Problem-Solving in Hospital Medicine: Introduces principles of evidence-based medicine, quality of evidence, interpretation of diagnostic tests, systemic reviews and meta-analysis, and knowledge translations to clinical practice. Approach to the Patient at the Bedside: Details the diagnosis, testing, and initial management of common complaints that may either precipitate admission or arise during hospitalization. Hospitalist Skills: Covers the interpretation of common “low tech” tests that are routinely accessible on admission, how to optimize the use of radiology services, and the standardization of the execution of procedures routinely performed by some hospitalists. Clinical Conditions: Reflects the expanding scope of Hospital Medicine by including sections of Emergency Medicine, Critical Care, Geriatrics, Neurology, Palliative Care, Pregnancy, Psychiatry and Addiction, and Wartime Medicine.
This book introduces a novel approach to discrete optimization, providing both theoretical insights and algorithmic developments that lead to improvements over state-of-the-art technology. The authors present chapters on the use of decision diagrams for combinatorial optimization and constraint programming, with attention to general-purpose solution methods as well as problem-specific techniques. The book will be useful for researchers and practitioners in discrete optimization and constraint programming. "Decision Diagrams for Optimization is one of the most exciting developments emerging from constraint programming in recent years. This book is a compelling summary of existing results in this space and a must-read for optimizers around the world." [Pascal Van Hentenryck]
Post-Translational Modifications of Proteins discusses several important topics of interest to researchers and students in protein chemistry and biochemistry, including the occurrence and function of hydroxylated residues and the three enzymes required for their formation; the damaging effects of reactions between sugars and proteins; ADP-riboosylation of proteins outside the nucleus; and Monod, Wyman, and Changeux's concerted model for allosteric control of enzyme activity exemplified by studies on glycogen phosphorylase. The application of Fast Atom Bombardment Mass Spectometry (FAB-MS) to studies on the structure and biosynthesis of various oligosaccharide moieties in protein is examined, and the understanding of the structural diversity and function of glycoprotein oligosaccharides is discussed in this volume.
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