Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
This dedicated volume of the Journal of the British Archaeological Association draws together ten papers which, collectively, explore something of the art and architecture, styles and uses, of the medieval cloister in England and Wales. Contributors consider the continental context, cloisters in English palaces, Benedictine and Augustinian cloister arcades in the 12th and 13th centuries, architecture and meaning in Cistercian east ranges, late medieval vaulted cloisters in the West Country, cloisters at the cathedrals of Old Sarum, Canterbury, and Lincoln, and assess the extent to which the cloister bosses at Norwich cathedral priory reflect contemporary religious politics. The volume also contains an extended consideration and gazetteer of all Cistercian cloisters in England and Wales.
Bacterial Endotoxic Lipopolysaccharides provides an up-to-date, two-volume review of the latest information regarding bacterial lipopolysaccharide structure and activities. These volumes cover the biochemistry, pharmacology, and pathophysiologic properties of endotoxins. The volumes also thoroughly discuss the strengths and weaknesses of new therapies for septic shock that are based on an immunological attack on endotoxins and the cytokines induced by endotoxins. All scientists involved in endotoxin research, clinical infectious disease specialists, and medical students interested in the pathogenesis of septic shock will find Bacterial Endotoxic Lipopolysaccharides invaluable as a reference resource.
Private associations organized around a common cult, occupation, ethnic identity, neighborhood or family were among the principal means of organizing social and economic life in the ancient Mediterranean. They offered opportunities for sociability, cultic activities, mutual support and contexts in which to display and recognize virtuous achievement. This volume collects 140 inscriptions and papyri from Ptolemaic and early Roman Egypt, along with translations, notes, commentary, and analytic indices. The dossier of association-related documents substantially enhances our knowledge of the extent, activities, and importance of private associations in the ancient Mediterranean, since papyri, unavailable from most other locations in the Mediterranean, preserve a much wider range of data than epigraphical monuments. The dossier from Egypt includes not only honorific decrees, membership lists, bylaws, dedications, and funerary monuments, but monthly accounts of expenditures and income, correspondence between guild secretaries and local officials, price and tax declarations, records of legal actions concerning associations, loan documents, petitions to local authorities about associations, letters of resignation, and many other papyrological genres. These documents provide a highly variegated picture of the governance structures and practices of associations, membership sizes and profiles, and forms of interaction with the State.
This extensive undertaking, Accelerator Mass Spectrometry, conducts an elaborate and comprehensive summary of one of the foremost catalysts of progress in scientific research. Accelerator mass spectrometry (AMS), an innovative analytical technique, measures rare atoms at unprecedented levels of sensitivity, revolutionizing the science of radiocarbon dating and accessing new natural radioisotopes as environmental tracers and chronometers. This book demonstrates how AMS is applied in the studies of extraterrestrial materials, the earth sciences, the future of the global environment, and the history of mankind. This compendium also highlights the significant impact of AMS on several fields of scientific investigation, spurring remarkable studies in global climate change, ancient artifacts, pollution, nuclear safeguards, geochronology, and materials characterization. The myriad of sample types and variety of applications in this examination include: Meteorites from Mars Ancient air trapped in Antarctic ice The Shroud of Turin The dating of human bones The colonization of the Americas and Australia Ancient rock art The crown of Charlemagne Cancerogenic effects of cooked meat The consequences of the Chernobyl accident The role of aluminum in Alzheimer's Disease This unique edition has compiled the diverse set of scientific literature into a single volume, suitable as a text or resource on the major AMS-related outcomes, issues, and methods.
How can governments persuade their citizens to act in socially beneficial ways? This ground-breaking book builds on the idea of 'light touch interventions' or 'nudges' proposed in Richard Thaler and Cass Sunstein's highly influential Nudge (2008). While recognising the power of this approach, it argues that an alternative also needs to be considered: a 'think' strategy that calls on citizens to decide their own priorities as part of a process of civic and democratic renewal. As well as setting out these divergent approaches in theory, the book provides evidence from a number of experiments to show how using 'nudge' or 'think' techniques works in practice. Updated and rewritten, this second edition features a new epilogue that reflects on recent developments in nudge theory and practice, introducing a radical version of nudge, ‘nudge plus’. There is also a substantial prologue by Cass Sunstein.
With an editorial team of leading experts from the American College of Emergency Physicians and the American Heart Association, this book is the first complete, clinically oriented reference textbook in emergency cardiovascular care and CPR. The book translates bench research to the clinician's bedside needs and addresses end-of-life issues. The content is appropriate for a large audience including early caregivers, emergency department and CCU nurses, students, residents, fellows, and hospitalists responsible for cardiovascular emergency situations. A companion Website will include the fully searchable text, instructional videos produced by the AHA, and links to ACC, AHA, ASE, ACEP, and ILCOR guidelines and policy statements.
The most comprehensive compendium of information available on calcium channels Calcium channels are a common component of the membranes of a wide range of excitable cells, and their presence is crucial to the functioning of these cells. This book presents a current review of the biophysics, physiology, pharmacology, and clinical role of calcium channels. Chapters discussing the biophysics of calcium channels include topics in ion permeation, channel activation, channel inactivation, and second messenger modulation. The chapters on physiology cover excitation-contraction coupling, excitation-secretion coupling, sensory transduction, regulation of electrical activity, and the regulation of cell growth and development. Issues discussed in the pharmacology chapters of the book include the effects of permeant and inhibitory inorganic ions, blocking and activating effects of organic ions, and the regulatory effects of naturally occurring compounds. The chapters exploring the clinical aspects of calcium channels examine topics such as the modulation of calcium channels in the treatment of ischemic heart disease, cardiomyopathies, hypertension, cardiac arrhythmias, peripheral vascular diseases, platelet-related disorders, neurological disorders, and psychiatric disorders. Physicians neuroscientists, and pharmacologists should consider this book essential to their reference collections.
This largely self-contained book on the theory of quantum information focuses on precise mathematical formulations and proofs of fundamental facts that form the foundation of the subject. It is intended for graduate students and researchers in mathematics, computer science, and theoretical physics seeking to develop a thorough understanding of key results, proof techniques, and methodologies that are relevant to a wide range of research topics within the theory of quantum information and computation. The book is accessible to readers with an understanding of basic mathematics, including linear algebra, mathematical analysis, and probability theory. An introductory chapter summarizes these necessary mathematical prerequisites, and starting from this foundation, the book includes clear and complete proofs of all results it presents. Each subsequent chapter includes challenging exercises intended to help readers to develop their own skills for discovering proofs concerning the theory of quantum information.
Ancient ice ages are revealed by distinctive stratal facies that tell us much about the times of coolness and how the climate system works. Several strong ice ages were recorded in the late Paleozic time and during transitions from the Devonian in to the Carboniferous and from the Ordovician in to the Silurian. In Precambrian time, several are documented for both the late and early Proterozoic age. This title explores findings on the pre-Mesozoic ice ages, examining climate in relation to tectonobiogeochemical activities rooted in the changing earth-air-ocean system.
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