John M. Watanabe's Books

Asymmetric Synthetic Methodology

By: David John Ager,Michael B. East

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Asymmetric Synthetic Methodology

By: David John Ager,Michael B. East

This comprehensive text presents a critical discussion of the scopes and limitations of various organic synthetic methodologies that are available for performing asymmetric transformations. In addition to purely chemical methods, the book covers applications of new enzymes and other biological systems that are increasingly useful in asymmetric methodology.

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505

Publisher

CRC Press

Published Date

ISBN 10

1000098494

ISBN 13

9781000098495

4D Electron Microscopy

Imaging in Space and Time

By: Ahmed H. Zewail,John Meurig Thomas

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4D Electron Microscopy

Imaging in Space and Time

By: Ahmed H. Zewail,John Meurig Thomas

Structural phase transitions, mechanical deformations, and the embryonic stages of melting and crystallization are examples of phenomena that can now be imaged in unprecedented structural detail with high spatial resolution, and ten orders of magnitude as fast as hitherto. No monograph in existence attempts to cover the revolutionary dimensions that EM in its various modes of operation nowadays makes possible. The authors of this book chart these developments, and also compare the merits of coherent electron waves with those of synchrotron radiation. They judge it prudent to recall some important basic procedural and theoretical aspects of imaging and diffraction so that the reader may better comprehend the significance of the new vistas and applications now afoot. This book is not a vade mecum - numerous other texts are available for the practitioner for that purpose.

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Page Count

359

Publisher

World Scientific

Published Date

ISBN 10

1848163916

ISBN 13

9781848163911

Modern Electrochemistry 2A

Fundamentals of Electrodics

By: John O'M. Bockris,Amulya K.N. Reddy,Maria E. Gamboa-Aldeco

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Modern Electrochemistry 2A

Fundamentals of Electrodics

By: John O'M. Bockris,Amulya K.N. Reddy,Maria E. Gamboa-Aldeco

This book had its nucleus in some lectures given by one of us (J. O’M. B. ) in a course on electrochemistry to students of energy conversion at the University of Pennsyl- nia. It was there that he met a number of people trained in chemistry, physics, biology, metallurgy, and materials science, all of whom wanted to know something about electrochemistry. The concept of writing a book about electrochemistry which could be understood by people with very varied backgrounds was thereby engendered. The lectures were recorded and written up by Dr. Klaus Muller as a 293-page manuscript. At a later stage, A. K. N. R. joined the effort; it was decided to make a fresh start and to write a much more comprehensive text. Of methods for direct energy conversion, the electrochemical one is the most advanced and seems the most likely to become of considerable practical importance. Thus, conversion to electrochemically powered transportation systems appears to be an important step by means of which the difficulties of air pollution and the effects of an increasing concentration in the atmosphere of carbon dioxide may be met. Cor- sion is recognized as having an electrochemical basis. The synthesis of nylon now contains an important electrochemical stage. Some central biological mechanisms have been shown to take place by means of electrochemical reactions. A number of American organizations have recently recommended greatly increased activity in training and research in electrochemistry at universities in the United States.

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812

Publisher

Springer Science & Business Media

Published Date

ISBN 10

0306476053

ISBN 13

9780306476051

Scientific Foundations of Clinical Assessment

By: Stephen N. Haynes,Gregory T. Smith,John D. Hunsley

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Scientific Foundations of Clinical Assessment

By: Stephen N. Haynes,Gregory T. Smith,John D. Hunsley

Scientific Foundations of Clinical Assessment is a user-friendly overview of the most important principles and concepts of clinical assessment. It provides readers with a science-based framework for interpreting assessment research and making good assessment decisions, such as selecting the best instruments and measures and interpreting the obtained assessment data. Written in a direct and highly readable fashion, with plenty of clinical examples that illustrate the relevance of psychometric principles and assessment research, this text is one every professional and graduate student needs to read. The second edition is expanded and fully updated, and includes additional coverage of the principles and methods of developing new assessment instruments.

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314

Publisher

Routledge

Published Date

ISBN 10

1351210556

ISBN 13

9781351210553

Management of Benign Pancreatic Disease, An Issue of Gastrointestinal Endoscopy Clinics

By: John Poneros

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Management of Benign Pancreatic Disease, An Issue of Gastrointestinal Endoscopy Clinics

By: John Poneros

With consultation of Dr. Charles J. Lightdale, Consulting Editor, Dr. Poneros has created created a state-of-the-art look at endoscopy for pancreatic disease. Top authors have contributed clinical reviews in the following areas: Acute Pancreatitis: Evidence Based Management Decisions ; Endoscopic Cyst Gastrostomy; ERCP for Recurrent Acute Pancreatitis ; Autoimmune Pancreatitis; Total Pancreatectomy with Autologous Islet Cell Transplantation; Pancreatic Insufficiency: What is the Gold Standard?; Current Guideline Controversies in the Management of Pancreatic Cystic Neoplasms; How to Manage Incidentally Found Pancreatic Neuroendocrine Tumors; Update in Celiac Block; The Use of Biomarkers in Risk Stratification of Cystic Neoplasms; Interventional EUS in the Pancreas; How to Avoid Post-ERCP Pancreatitis; and The Role of Genetic in Pancreatitis. Readers will come away with the clinical information they need to utilize endoscopic procedures in the treatment and management of pancreatic disease.

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217

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323642268

ISBN 13

9780323642262

Maya Saints and Souls in a Changing World

By: John M. Watanabe

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Maya Saints and Souls in a Changing World

By: John M. Watanabe

The Maya of Santiago Chimaltenango have experienced increasingly rapid, even violent, integration into Guatemalan society in the last fifty years, yet they still distinguish themselves ethnically from Spanish-speaking Guatemalans and other Maya. Why this sense of ethnic identity persists—and also changes—over time is the focus of Maya Saints and Souls in a Changing World, a beautifully written ethnography of a Mam-speaking Maya town in the western highlands of Guatemala. John Watanabe uniquely explores how Chimaltecos themselves define their local distinctiveness. This approach uncovers significant continuities in lifeways and world view that might otherwise remain imperceptible to an outsider. Another important feature of the study is that it updates Charles Wagley's pioneering research in the community during the 1930s. Watanabe identifies both the external, historical factors that have prompted change in the community since Wagley's time and the people's responses to these changes.

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Page Count

298

Publisher

University of Texas Press

Published Date

ISBN 10

0292786735

ISBN 13

9780292786738

Ischemic Cerebrovascular Disease

By: Harold P. Adams, Jr.,Vladimir C. Hachinski,John W. Norris

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Ischemic Cerebrovascular Disease

By: Harold P. Adams, Jr.,Vladimir C. Hachinski,John W. Norris

This book provides a comprehensive clinical review of the diagnosis and treatment of patients with ischemic cerebrovascular disease. The book includes chapters on the clinical features of transient ischemic attacks and ischemic stroke, risk factors, and evaluations. Additional chapters discuss causes of stroke including atherosclerosis, cardioembolism, non-atherosclerotic vasculopathies, and pro-thrombotic disorders. The causes of stroke in children and young adults are highlighted. The final section of the book includes chapters on therapies to prevent stroke, acute stroke treatment, general management of the patient with recurrent stroke, and rehabilitation. The volume is heavily referenced with an emphasis on recent publications so that the reader can pursue additional information about a topic. It also includes several tables and algorithms that should aid the clinician treating patients with cerebrovascular disease.

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Page Count

594

Publisher

Contemporary Neurology

Published Date

ISBN 10

0195132890

ISBN 13

9780195132892

Handbook of VLSI Microlithography, 2nd Edition

By: John N. Helbert

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Handbook of VLSI Microlithography, 2nd Edition

By: John N. Helbert

This handbook gives readers a close look at the entire technology of printing very high resolution and high density integrated circuit (IC) patterns into thin resist process transfer coatingsùincluding optical lithography, electron beam, ion beam, and x-ray lithography. The book's main theme is the special printing process needed to achieve volume high density IC chip production, especially in the Dynamic Random Access Memory (DRAM) industry. The book leads off with a comparison of various lithography methods, covering the three major patterning parameters of line/space, resolution, line edge and pattern feature dimension control. The book's explanation of resist and resist process equipment technology may well be the first practical description of the relationship between the resist process and equipment parameters. The basics of resist technology are completely coveredùincluding an entire chapter on resist process defectivity and the potential yield limiting effect on device production. Each alternative lithographic technique and testing method is considered and evaluated: basic metrology including optical, scanning-electron-microscope (SEM) techniques and electrical test devices, along with explanations of actual printing tools and their design, construction and performance. The editor devotes an entire chapter to today's sophisticated, complex electron-beam printers, and to the emerging x-ray printing technology now used in high-density CMOS devices. Energetic ion particle printing is a controllable, steerable technology that does not rely on resist, and occupies a final section of the handbook.

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Page Count

1026

Publisher

Cambridge University Press

Published Date

ISBN 10

0080946801

ISBN 13

9780080946801

Volume 1: Modern Electrochemistry

Ionics

By: John O'M. Bockris,Amulya K.N. Reddy

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Volume 1: Modern Electrochemistry

Ionics

By: John O'M. Bockris,Amulya K.N. Reddy

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Page Count

814

Publisher

Springer Science & Business Media

Published Date

ISBN 10

030646909X

ISBN 13

9780306469091

Handbook of VLSI Microlithography

By: John N. Helbert

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Handbook of VLSI Microlithography

By: John N. Helbert

This handbook gives readers a close look at the entire technology of printing very high resolution and high density integrated circuit (IC) patterns into thin resist process transfer coatingsùincluding optical lithography, electron beam, ion beam, and x-ray lithography. The book's main theme is the special printing process needed to achieve volume high density IC chip production, especially in the Dynamic Random Access Memory (DRAM) industry. The book leads off with a comparison of various lithography methods, covering the three major patterning parameters of line/space, resolution, line edge and pattern feature dimension control. The book's explanation of resist and resist process equipment technology may well be the first practical description of the relationship between the resist process and equipment parameters. The basics of resist technology are completely coveredùincluding an entire chapter on resist process defectivity and the potential yield limiting effect on device production.Each alternative lithographic technique and testing method is considered and evaluated: basic metrology including optical, scanning-electron-microscope (SEM) techniques and electrical test devices, along with explanations of actual printing tools and their design, construction and performance. The editor devotes an entire chapter to today's sophisticated, complex electron-beam printers, and to the emerging x-ray printing technology now used in high-density CMOS devices. Energetic ion particle printing is a controllable, steerable technology that does not rely on resist, and occupies a final section of the handbook.

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1025

Publisher

William Andrew

Published Date

ISBN 10

0815517807

ISBN 13

9780815517801

Evolution of Island Mammals

Adaptation and Extinction of Placental Mammals on Islands

By: Alexandra van der Geer,George Lyras,John de Vos,Michael Dermitzakis

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Evolution of Island Mammals

Adaptation and Extinction of Placental Mammals on Islands

By: Alexandra van der Geer,George Lyras,John de Vos,Michael Dermitzakis

Evolution on islands differs in a number of important ways from evolution on mainland areas. Over millions of years of isolation, exceptional and sometimes bizarre mammals evolved on islands, such as pig-sized elephants and hippos, giant rats and gorilla-sized lemurs that would have been formidable to their mainland ancestors. This timely and innovative book is the first to offer a much-needed synthesis of recent advances in the exciting field of the evolution and extinction of fossil insular placental mammals. It provides a comprehensive overview of current knowledge on fossil island mammals worldwide, ranging from the Oligocene to the onset of the Holocene. The book addresses evolutionary processes and key aspects of insular mammal biology, exemplified by a variety of fossil species. The authors discuss the human factor in past extinction events and loss of insular biodiversity. This accessible and richly illustrated textbook is written for graduate level students and professional researchers in evolutionary biology, palaeontology, biogeography, zoology, and ecology.

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Page Count

512

Publisher

John Wiley & Sons

Published Date

ISBN 10

1444391283

ISBN 13

9781444391282

Geographic Information Science and Mountain Geomorphology

By: Michael Bishop,John F. Shroder

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Geographic Information Science and Mountain Geomorphology

By: Michael Bishop,John F. Shroder

From the reviews: "Bishop and Schroder (both, Univ. of Nebraska at Omaha) have brought together an impressive group of practitioners in the relatively new application of geographic information science to mountain geomorphology. In doing so, they have produced valuable, first, overall coverage of a high-tech approach to mountain, three-dimensional research. More than 40 contributing authors discuss a wide range of related aspects.... The book is well bound and well produced; each chapter provides an extensive source of references. The numerous line drawings are clearly reproduced, although the mediocre quality of photographic reproduction limits the value of air photographs and satellite images. As is characteristic of many edited collections, there is some variation in chapter quality. Some of the writing is so dense that it requires minute concentration--one chapter, for instance, has 14 pages of references from a total of 43 pages. Nevertheless, this is a vital compendium for a rapidly expanding field of research. Summing Up: Recommended. Upper-division undergraduates through professionals." (J. D. Ives, Choice, March 2005)

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564

Publisher

Springer Science & Business Media

Published Date

ISBN 10

354042640X

ISBN 13

9783540426400

A Handbook of Derivatives for Mass Spectrometry

By: Vladimir Zaikin,John M. Halket

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A Handbook of Derivatives for Mass Spectrometry

By: Vladimir Zaikin,John M. Halket

Chemical derivatisation of functional groups has proved popular since the beginning of organic mass spectrometry as a means to enhance the stability and volatility of the analytes as well as facilitating structure elucidation. This book provides comprehensive information on the wide range of derivatisation methods. Each chapter looks at a particular area of derivatisation and includes extensive references to the literature for further research where necessary. There are nearly 1800 references, which, as well as full bibliographic information, include chapter/paper titles where appropriate and Digital Object Identifiers (DOIs) to allow easy retrieval of the online version of the referenced publication. The emergence of atmospheric pressure ionisation and other soft ionisation techniques has not diminished the interest in such chemical techniques, as witnessed by the many chemical tags used in quantitative proteomics (Chapter 9). The last two chapters, a substantial part of the book, deal with derivatisation for use with soft ionisation of both small and large molecules. Chapters Silylation Acylation Alkylation (Arylation) Cyclic derivatives Monofunctional compounds Polyfunctional compounds On-line derivatisation/degradation Soft ionisation—small molecules Soft ionisation—large molecules

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Page Count

545

Publisher

IM Publications

Published Date

ISBN 10

1901019098

ISBN 13

9781901019094

Electron Microscopy and Analysis 1997, Proceedings of the Institute of Physics Electron Microscopy and Analysis Group Conference, University of Cambridge, 2-5 September 1997

By: John M. Rodenburg

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Electron Microscopy and Analysis 1997, Proceedings of the Institute of Physics Electron Microscopy and Analysis Group Conference, University of Cambridge, 2-5 September 1997

By: John M. Rodenburg

Electron Microscopy and Analysis 1997 celebrates the centenary anniversary of the discovery of the electron by J.J. Thomson in Cambridge and the fiftieth anniversary of this distinguished Institute group. The book includes papers on the early history of electron microscopy (from P. Hawkes), the development of the scanning electron microscope at Cambridge (from K. Smith), electron energy loss spectroscopy (from L.M. Brown), imaging methods (from J. Spence), and the future of electron microscopy (from C. Humphreys). Covering a wide range of applications of advanced techniques, it discusses electron imaging, electron energy-loss and x-ray analysis, and scanning probe and electron beam microscopies. This volume is a handy reference for professionals using microscopes in all areas of physics, materials science, metallurgy, and surface science to gain an overview of developments in our understanding of materials microstructure and of advances in microscope interrogation techniques.

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Page Count

708

Publisher

CRC Press

Published Date

ISBN 10

1000112306

ISBN 13

9781000112306

Bradley's Neurology in Clinical Practice E-Book

By: Robert B. Daroff,Joseph Jankovic,John C Mazziotta,Scott L Pomeroy

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Bradley's Neurology in Clinical Practice E-Book

By: Robert B. Daroff,Joseph Jankovic,John C Mazziotta,Scott L Pomeroy

Comprehensive, easy to read, and clinically relevant, Bradley’s Neurology in Clinical Practice provides the most up-to-date information presented by a veritable "Who's Who" of clinical neuroscience. Its unique organization allows users to access content both by presenting symptom/sign and by specific disease entities—mirroring the way neurologists practice. A practical, straightforward style; templated organization; evidence-based references; and robust interactive content combine to make this an ideal, dynamic resource for both practicing neurologists and trainees. Authoritative, up-to-date guidance from Drs. Daroff, Jankovic, Mazziotta, and Pomeroy along with more than 150 expert contributors equips you to effectively diagnose and manage the full range of neurological disorders. Easy searches through an intuitive organization by both symptom and grouping of diseases mirrors the way you practice. The latest advances in clinical neurogenetics, brain perfusion techniques for cerebrovascular disease, the relationship between neurotrauma and neurodegenerative disease, management strategies for levodopa-related complications in movement disorders, progressive neuropsychiatric disorders arising from autoimmune encephalitis, and more keep you at the forefront of your field. Reorganized table of contents which includes new chapters on: Brain Death, Vegetative, and Minimally Conscious States; Deep Brain Stimulation; Sexual Dysfunction in Degenerative and Spinal Cord Disorders; Sports and Performance Concussion; Effects of Drug Abuse on the Nervous System; and Mechanisms of Neurodegenerative Disorders. Regular online updates reflect the latest information on the diagnosis and treatment of neurologic diseases based on the latest recommendations and methodologies. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

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2845

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323339166

ISBN 13

9780323339162

Handbook of Immune Response Genes

By: Tak W. Mak,John J. L. Simard

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Handbook of Immune Response Genes

By: Tak W. Mak,John J. L. Simard

The study of immunology encompasses a vast and ever-growing body of information that in some way or other incorporates most areas of medical biological research. As the body of information in the medical sciences continues to increase its rate of expansion, one of the greatest challenges to investigators will be to integrate this information in a manner that is intellectually fruitful and productive. Considering the intended scope of this text, we could not pretend to have gone too far toward achieving such an integration--and considering the pace of change, in its very best form a measured approximation of such lofty goals might be the most we could hope for. Nevertheless, in these pages we have sought to produce a collection of information that is at once concise and up-to-date regarding areas where important developments are impacting on the way we understand the vertebrate immune system. In addition, although the information is geared toward advanced study, we have discussed some basic elements and concepts that we hope make the text a useful resource for both the immunologist and the nonspecialist. The intention is to provide the researcher, clinician, or advanced undergraduate student with a brief ov- view of specific components of the immune system, and to provide a place from which to begin further detailed study if necessary. To this end, we made every effort to supply extensive referencing--although limitations in space prevented exhaustive or complete referencing in some cases.

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Page Count

402

Publisher

Springer Science & Business Media

Published Date

ISBN 10

0585311803

ISBN 13

9780585311807

Kucers' The Use of Antibiotics Sixth Edition

A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

By: M Lindsay Grayson,Suzanne M Crowe,James S McCarthy,John Mills,Johan W Mouton,S Ragnar Norrby,David L Paterson,Michael A Pfaller

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Kucers' The Use of Antibiotics Sixth Edition

A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs

By: M Lindsay Grayson,Suzanne M Crowe,James S McCarthy,John Mills,Johan W Mouton,S Ragnar Norrby,David L Paterson,Michael A Pfaller

I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics

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Page Count

3211

Publisher

CRC Press

Published Date

ISBN 10

1444147528

ISBN 13

9781444147520

Convective Flow Boiling

By: John C. Chen

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Convective Flow Boiling

By: John C. Chen

This book comprises selected papers from the First International Conference on Convective Flow Boiling. The purpose of the conference is to examine state-of-science and recent developments in technology of flow boiling, i.e., boiling systems which are affected by convective flows.

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402

Publisher

CRC Press

Published Date

ISBN 10

1000716031

ISBN 13

9781000716030

The Molecular Basis of Cancer

Expert Consult - Online

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

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The Molecular Basis of Cancer

Expert Consult - Online

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.

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1948

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437710999

ISBN 13

9781437710991

Principles and Practice of Palliative Care and Supportive Oncology

By: Ann M. Berger,John L. Shuster, Jr.,Jamie H. Von Roenn

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Principles and Practice of Palliative Care and Supportive Oncology

By: Ann M. Berger,John L. Shuster, Jr.,Jamie H. Von Roenn

Unlike other textbooks on this subject, which are more focused on end of life, the 4th edition of Principles and Practice of Palliative Care and Supportive Oncology focuses on supportive oncology. In fact, the goal of this textbook is to provide a source of both help and inspiration to all those who care for patients with cancer. Written in a more reader-friendly format, this textbook not only offers authoritative and up-to-date reviews of research and clinical care best practices, but also practical clinical applications to help readers put everything they learn to use.

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Page Count

1950

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1469822512

ISBN 13

9781469822518

Microspheres and Regional Cancer Therapy

By: Neville Willmott,John M. Daly

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Microspheres and Regional Cancer Therapy

By: Neville Willmott,John M. Daly

Microspheres and Regional Cancer Therapy takes an interdisciplinary approach to the subject of microspheres and regional cancer therapy. It synthesizes laboratory and clinical data to demonstrate the utility of microsphere-based strategies in the treatment of localized solid tumors (particularly in the liver) not amenable to surgery and as a component of strategies for treatment of disseminated disease. Using the same techniques that show the deficiencies of delivery strategies involving antibodies, liposomes, and synthetic polymers, clear evidence is presented describing how microspheres of appropriate size can be localized in solid tumor deposits in the liver with little exposure to other organs. To exploit this phenomenon, the extent and nature of the incorporation of active agents within microspheres is discussed in relation to release, pharmacokinetics, and tumor response achieved by intensification of therapy in the manner described. This book will benefit laboratory-based scientists and clinicians in pharmaceutics, pharmacology, physiology, surgical oncology, and nuclear medicine. In addition, cancer clinicians interested in the value of regional therapy will be able to evaluate the underlying theory and learn the necessary methodology.

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258

Publisher

CRC Press

Published Date

ISBN 10

1000098893

ISBN 13

9781000098891

Nutrition and Science

A Darwinian Perspective on Nutritional Medicine

By: John Nichols

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Nutrition and Science

A Darwinian Perspective on Nutritional Medicine

By: John Nichols

This book offers a completely up-to-date summary of nutritional medicine as it applies to frontline medical professionals, medical students and the interested layperson. Newspapers often give contradictory and confusing reports on issues such as alcohol intake, dietary sugars versus fats and the value (or lack thereof) of taking supplements. In addition, many GPs are as confused as their patients on these matters as they get very little education in nutrition either at medical school or afterwards. However, nutritional medicine is not really that confusing. There is some disagreement among experts, but there is a consensus on the most important issues, albeit with slight variations. The book summarises these generally agreed opinions, but explains where there are differences of opinion, detailing the reasons for these.

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Page Count

511

Publisher

Cambridge Scholars Publishing

Published Date

ISBN 10

1527523136

ISBN 13

9781527523135

Heterogeneous Integrations

By: John H. Lau

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Heterogeneous Integrations

By: John H. Lau

Heterogeneous integration uses packaging technology to integrate dissimilar chips, LED, MEMS, VCSEL, etc. from different fabless houses and with different functions and wafer sizes into a single system or subsystem. How are these dissimilar chips and optical components supposed to talk to each other? The answer is redistribution layers (RDLs). This book addresses the fabrication of RDLs for heterogeneous integrations, and especially focuses on RDLs on: A) organic substrates, B) silicon substrates (through-silicon via (TSV)-interposers), C) silicon substrates (bridges), D) fan-out substrates, and E) ASIC, memory, LED, MEMS, and VCSEL systems. The book offers a valuable asset for researchers, engineers, and graduate students in the fields of semiconductor packaging, materials sciences, mechanical engineering, electronic engineering, telecommunications, networking, etc.

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381

Publisher

Springer

Published Date

ISBN 10

9811372241

ISBN 13

9789811372247

Bubbles, Drops, and Particles

By: Roland Clift,John R. Grace,Martin E. Weber

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Bubbles, Drops, and Particles

By: Roland Clift,John R. Grace,Martin E. Weber

This volume offers a critical review of the literature concerning the fluid dynamics, heat transfer, and mass transfer of single bubbles, drops, and particles. Upper-level undergraduates and graduate students, as well as professionals in the fields of engineering, physics, chemistry, geophysics, and applied mathematics, will find it a unified treatment of solid particles, liquid drops, and gas bubbles. Starting with a summary of the fundamental principles and equations governing the behavior of bubbles, drops, and solid particles in Newtonian fluids, the text proceeds to a survey of the parameters used to characterize the shape of rigid particles, and of the factors that determine the shape of bubbles and drops. Succeeding chapters examine the behavior of solid and fluid particles under steady incompressible flow in an extended external phase. The text concludes with an exploration of effects that complicate the relatively simple case of a particle moving steadily through an unbounded fluid.

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402

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Courier Corporation

Published Date

ISBN 10

0486445801

ISBN 13

9780486445809

Diseases of the Small Intestine in Childhood, Fourth Edition

By: John Walker-Smith,Simon Murch

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Diseases of the Small Intestine in Childhood, Fourth Edition

By: John Walker-Smith,Simon Murch

Provides a review of diseases of the small intestine in children, with an emphasis upon a discussion of their causes, clinical manifestations and the newer techniques which are used in diagnosis as well as modern methods of management. The book will be of value to the consultant paediatrician and paediatric surgeon as well as to the paediatric registrar and house officer as a practical guide to their understanding of these diseases. It is also intended for adult physicians, gastroenterologists and surgeons who wish to survey the clinical spectrum of disease of the small intestine in childhood.

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1096

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CRC Press

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ISBN 10

1901865053

ISBN 13

9781901865059

Epigenetics, Nuclear Organization & Gene Function

With implications of epigenetic regulation and genetic architecture for human development and health

By: John C. Lucchesi

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Epigenetics, Nuclear Organization & Gene Function

With implications of epigenetic regulation and genetic architecture for human development and health

By: John C. Lucchesi

Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself (the complex of DNA, histones and non-histone proteins referred to as chromatin), and its distribution within a functionally compartmentalized nucleus. This architectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information.

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240

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Oxford University Press

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ISBN 10

0192567160

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9780192567161

Tachdjian's Pediatric Orthopaedics: From the Texas Scottish Rite Hospital for Children E-Book

2-Volume Set

By: John A. Herring

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Tachdjian's Pediatric Orthopaedics: From the Texas Scottish Rite Hospital for Children E-Book

2-Volume Set

By: John A. Herring

With complete coverage appropriate for residents through experienced pediatric orthopaedic surgeons, Tachdjian's Pediatric Orthopaedics, 6th Edition, continues a 50-year tradition of excellence as the most comprehensive, authoritative guide to diagnosing and treating pediatric musculoskeletal disorders. Editor John Herring, MD, and experts from the Texas Scottish Rite Hospital for Children offer step-by-step instruction and detailed visual guidance on both surgical and non-surgical approaches. It's everything the orthopaedic surgeon needs to know to accurately treat the full spectrum of pediatric orthopaedic conditions and injuries. - Presents complete coverage of the latest knowledge on etiology, imaging, differential diagnosis, growth instrumentation, and non-operative and surgical techniques for a wide range of pediatric orthopaedic conditions. - Provides expert guidance on difficult diagnostic and clinical management issues for your most challenging cases. - Covers today's most effective approaches for management of severe spinal deformities, early onset scoliosis, hip preservation methods, long-term follow-up of trauma conditions, and much more. - Offers superb visual guidance with nearly 2,500 full-color illustrations and 70 videos (many are new!) of pediatric surgical procedures, including a number that highlight clinical examination and unusual clinical findings. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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2566

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323566952

ISBN 13

9780323566957

Handbook of Heterocyclic Chemistry

By: Alan R. Katritzky,Christopher A. Ramsden,John A. Joule,Viktor V. Zhdankin

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Handbook of Heterocyclic Chemistry

By: Alan R. Katritzky,Christopher A. Ramsden,John A. Joule,Viktor V. Zhdankin

Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. - Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work - Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts - Features 35% new material to compliment the completely revised text

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1011

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Elsevier

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ISBN 10

0080958443

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9780080958446

Abeloff's Clinical Oncology E-Book

By: John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper

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Abeloff's Clinical Oncology E-Book

By: John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper

Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up. - Includes new chapters on Cancer Metabolism and Clinical Trial Designs in Oncology and a standalone chapter on lifestyles and cancer prevention. - Features extensive updates including the latest clinical practice guidelines, decision-making algorithms, and clinical trial implications, as well as new content on precision medicine, genetics, and PET/CT imaging. - Includes revised diagnostic and treatment protocols for medical management, surgical considerations, and radiation oncology therapies, stressing a multispecialty, integrated approach to care. - Helps you find information quickly with updated indexing related to management recommendations, focused fact summaries, updated key points at the beginning of each chapter ideal for quick reference and board review, and algorithms for patient evaluation, diagnosis, and treatment options. - Offers more patient care coverage in disease chapters, plus new information on cancer as a chronic illness and cancer survivorship. - Discusses today's key topics such as immuno-oncology, functional imaging, precision medicine, the application of genetics in pathologic diagnosis and sub-categorization of tumors as well as the association of chronic infectious diseases such as HIV and cancer. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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2648

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323568157

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9780323568159

The Genetics and Molecular Biology of Neural Tumors

By: Avery A. Sandberg,John F. Stone

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The Genetics and Molecular Biology of Neural Tumors

By: Avery A. Sandberg,John F. Stone

Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, this book provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors. This book is the first of its kind, encyclopedic and wide-ranging.

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453

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1597455105

ISBN 13

9781597455107

Tempests, Poxes, Predators, and People

Stress in Wild Animals and How They Cope

By: L.Michael Romero,John C. Wingfield

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Tempests, Poxes, Predators, and People

Stress in Wild Animals and How They Cope

By: L.Michael Romero,John C. Wingfield

Although scientists have discovered many fundamental physiological and behavioral mechanisms that comprise the stress response, most of current knowledge is based on laboratory experiments using domesticated or captive animals. Scientists are only beginning, however, to understand how stress impacts wild animals - by studying the nature of the stressful stimuli that animals in their natural environments have adapted to for survival, and what the mechanisms that allow that survival might be. This book summarizes, for the first time, several decades of work on understanding stress in natural contexts. The aim is two-fold. The first goal of this work is to place modern stress research into an evolutionary context. The stress response clearly did not evolve to cause disease, so that studying how animals use the stress response to survive in the wild should provide insight into why mechanisms evolved the way that they did. The second goal is to provide predictions on how wild animals might cope with the Anthropocene, the current period of Earth's history characterized by the massive human remodeling of habitats on a global scale. Conservation of species will rely upon how wild animals use their stress response to successfully cope with human-created stressors.

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625

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Oxford University Press

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ISBN 10

0199710597

ISBN 13

9780199710591

Heterocyclic Chemistry

By: John A. Joule,Keith Mills

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Heterocyclic Chemistry

By: John A. Joule,Keith Mills

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

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719

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118681649

ISBN 13

9781118681640

The Selected Papers of Sir John Meurig Thomas

By: John Meurig Thomas

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The Selected Papers of Sir John Meurig Thomas

By: John Meurig Thomas

John Meurig Thomas is a former Director of the Royal Institution of Great Britain, a former head of the Department of Physical Chemistry and former Master of Peterhouse, University of Cambridge. A world-renowned solid-state, materials and surface chemist, he has been an educator, researcher, academic administrator, author of university texts, government advisor, industrial consultant and trustee of national museums in a career spanning over 50 years. Recipient of many international awards, including the Linus Pauling, Willard–Gibbs, Kapitza, Natta, Stokes, Davy and Faraday medals, he is also a fellow of the Royal Society (1977), of the American Philosophical Society (1993) and of ten other national academies. He is best known for his fundamental work in heterogeneous catalysis, chemical electron microscopy and in the popularisation of science, for which, in conjunction with his services to chemistry, he was knighted (1991). He is also founding editor of three scientific journals and editor or co-editor of some 30 monographs. A new mineral, meurigite, was named in his honour (1995). Most recently in 2016, Sir John was awarded the Royal Medal for Physical Sciences by the Royal Society. Drawn from over 1200 publications, this volume contains a summarised account of Sir John's work, with a selection of the new techniques pioneered and discovered by him and his colleagues. Also included are popular science articles, and various illustrations of techniques which have enhanced our knowledge of many facets of condensed matter science. Contributions from 80 peers, colleagues, former co-workers, students and friends worldwide who have interacted with or been influenced by him are a tribute to the professional and personal life of Sir John, making this book a unique reflective summary of the work of one of the greatest achievers in modern British physical science.

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622

Publisher

World Scientific Publishing Company

Published Date

ISBN 10

1786341875

ISBN 13

9781786341877

Biomedical Applications of Microprobe Analysis

By: Peter Ingram,John D. Shelburne,Victor L. Roggli,Ann LeFurgey

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Biomedical Applications of Microprobe Analysis

By: Peter Ingram,John D. Shelburne,Victor L. Roggli,Ann LeFurgey

Biomedical Applications of Microprobe Analysis is a combination reference/laboratory manual for the use of microprobe analysis in both clinical diagnostic and research settings. Also called microchemical microscopy, microprobe analysis uses high-energy bombardment of cells and tissue, in combination with high resolution EM or confocal microscopy to provide a profile of the ion, metal, and mineral concentrations present in a sample. This allows insight into the physiology and pathophysiology of a wide variety of cells and tissues.This book describes methods for obtaining detailed information about the identity and composition of particles too small to be seen with the naked eye and describes how this information can be useful in diagnostic and biomedical research. - Up-to-date review of electron microprobe analysis - Detailed descriptions of sample preparation techniques - Recent technologies including confocal microscopy, infrared microspectroscopy, and laser raman spectroscopy - Over 100 illustrations with numerous specific applications - Contributions by world-renowned experts in the field - Brief summary of highlights precedes each chapter

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573

Publisher

Academic Press

Published Date

ISBN 10

0080524567

ISBN 13

9780080524566

Head and Neck Cancer

Emerging Perspectives

By: John Frederick Ensley,Silvio Gutkind,John A. Jacobs,Scott Lippman

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Head and Neck Cancer

Emerging Perspectives

By: John Frederick Ensley,Silvio Gutkind,John A. Jacobs,Scott Lippman

By detailing experimental and basic research, from premalignancy to fully invasive tumors, this book has wide applicability to all human carcinomas. No other group of human cancers is better positioned for the application of recently developed novel and targeted therapies, and this book uniquely presents the unusual opportunities tumors of the head and neck provide for clinical, translational, and basic science research. Cutting-edge and experimental treatment approaches are presented, along with future strategies and an evaluation of emerging technologies. - Presents a multi-disciplinary perspective from authorities in diverse fields - Addresses state-of-the art approaches in cancer research as well as other scientific opportunities in this field - Provides comprehensive yet easily comprehendible source of information

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631

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Elsevier

Published Date

ISBN 10

0080533841

ISBN 13

9780080533841

The Emergence of Drugs which Block Calcium Entry

By: Ronald D. Smith,Peter S. Wolf,John R. Regan,Stanley R. Jolly

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The Emergence of Drugs which Block Calcium Entry

By: Ronald D. Smith,Peter S. Wolf,John R. Regan,Stanley R. Jolly

Calcium Entry Blockers (CEBs) are a new class of drugs which have been pushing back the frontiers of science and medicine for almost two decades. This report reviews some of the wealth of chemical, biological and clinical data describing the discovery and development of these compounds. The scientific importance, therapeutic benefit and marketing potential of these compounds have caused an explosion of scientific literature describing their effects in many preclinical and clinical settings. The definitional characteristics of these compounds suggest a certain predictability of their biological profile but their therapeutic usefulness varies widely dependent upon their physical properties, net hemodynamic effects, duration of action and incidence of side effects. CEBs appear uniquely suited to the treatment of the underlying complexity of cardiovascular disease. The CEBs of the future may live up to the expectations of pathophysiologically based therapeutics and allow the heart and blood vessels to outlive the cells which they support. The development of CEBs is an evolving story of epic proportions and represents the cooperative efforts of individuals in all areas of science.

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163

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Springer Science & Business Media

Published Date

ISBN 10

3642732283

ISBN 13

9783642732287

Freshwater Algae of North America

Ecology and Classification

By: John D. Wehr

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Freshwater Algae of North America

Ecology and Classification

By: John D. Wehr

Freshwater algae are among the most diverse and ubiquitous organisms on earth. They occupy an enormous range of ecological conditions from lakes and rivers to acidic peat swamps, inland saline lakes, snow and ice, damp soils, wetlands, desert soils, wastewater treatment plants, and are symbionts in and on many plants, fungi, and animals. In North America, the variety of freshwater habitats colonized by algae is very rich, and offers an enormous and fascinating range of environments for their study. They form the base of most aquatic food webs and are critical to studies of ecosystem health. Algal ecologists and taxonomists play an important role in the understanding of aquatic ecosystems: their biodiversity, productivity, interactions with other organisms, and water quality. This book provides in one volume a practical and comprehensive guide to the genera of freshwater algae known from North America. The format combines the necessary ecological, taxonomic and methodological information for all scientists working in aquatic environments, whether their specialty is in environmental monitoring and water quality assessment, biological composition, ecology, evolution, or molecular biology.Key Features* The first complete accounting of North America's freshwater algal genera in more than 50 years* Includes a guide to the current literature on species identification in each group of algae* High-quality photographs and drawings of more than 770 genera* A clear, easy-to-use introductory key to the diagnostic chapters* Synthetic chapters on freshwater habitats, use of algae in environmental assessment, and control of nuisance algae* Contributions from 27 experts in all areas of freshwater algae* Extensive literature citations* Companion volume of Ecology and Classification of North American Freshwater Invertebrates 2nd edition, edited by Throp and Covich

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935

Publisher

Elsevier

Published Date

ISBN 10

0080521886

ISBN 13

9780080521886

Book's by John M. Watanabe

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