An accessible and self-contained introduction to statistical models-now in a modernized new edition Generalized, Linear, and Mixed Models, Second Edition provides an up-to-date treatment of the essential techniques for developing and applying a wide variety of statistical models. The book presents thorough and unified coverage of the theory behind generalized, linear, and mixed models and highlights their similarities and differences in various construction, application, and computational aspects. A clear introduction to the basic ideas of fixed effects models, random effects models, and mixed models is maintained throughout, and each chapter illustrates how these models are applicable in a wide array of contexts. In addition, a discussion of general methods for the analysis of such models is presented with an emphasis on the method of maximum likelihood for the estimation of parameters. The authors also provide comprehensive coverage of the latest statistical models for correlated, non-normally distributed data. Thoroughly updated to reflect the latest developments in the field, the Second Edition features: A new chapter that covers omitted covariates, incorrect random effects distribution, correlation of covariates and random effects, and robust variance estimation A new chapter that treats shared random effects models, latent class models, and properties of models A revised chapter on longitudinal data, which now includes a discussion of generalized linear models, modern advances in longitudinal data analysis, and the use between and within covariate decompositions Expanded coverage of marginal versus conditional models Numerous new and updated examples With its accessible style and wealth of illustrative exercises, Generalized, Linear, and Mixed Models, Second Edition is an ideal book for courses on generalized linear and mixed models at the upper-undergraduate and beginning-graduate levels. It also serves as a valuable reference for applied statisticians, industrial practitioners, and researchers.
Each year, Elsevier’s Advances in Surgery reviews the latest techniques, data, and evidence in general surgery. A distinguished editorial board, led by Dr. John L. Cameron of Johns Hopkins, identifies current areas of major progress and controversy, and invites specialists from around the world to contribute comprehensive, detailed reviews on these topics.
MONITORING FOR HEALTH HAZARDS AT WORK Monitoring for Health Hazards at Work remains the seminal textbook on measuring and controlling the risk of workplace exposure to physical, chemical, and biological hazards. Designed for students studying occupational hygiene and exposure science, this comprehensive and accessible volume provides step-by-step guidance on identifying hazards and quantifying their risks in various workplace environments. Complete with checklists and practical examples, the authors present clear explanations of all types of hazards that can arise in the workplace, including dust, particles, fibrous aerosols, gases, vapours, and bioaerosols. The fifth edition features revised material throughout, and remains an essential resource for students and professionals in occupational hygiene, reflecting global standards and recent developments in monitoring equipment, modelling methods, exposure assessment, and legislation on workplace safety. Several new or substantially revised chapters cover topics such as human biomonitoring, exposure modelling, hazardous substances, physical agents, evaluating ventilation, PPE, and other control measures Updated sections discuss the equipment currently available, the importance of risk communication, assessing dermal and inadvertent ingestion exposures, and more Examines common workplace comfort issues such as noise, vibration, heat and cold, and lighting Offers practical advice on conducting and presenting risk assessments and reports Discusses the future of the development and application of hazard measurement equipment and methods Monitoring for Health Hazards at Work, is required reading for students and professionals in occupational hygiene, environmental health and safety, occupational health and safety, and exposure science.
Treatment of Skin Disease: Comprehensive Therapeutic Strategies has been thoroughly revised to give you the latest treatment options for dermatologic conditions. Mark G. Lebwohl, Warren R. Heymann, John Berth-Jones, and Ian Coulson present an intuitive and easy-to-use, definitive treatment reference that covers the full range of choices for each condition so that you are prepared even when your patients do not respond to primary or secondary therapies. With new chapters on today’s hot topics-methocillin-resistant staphylococcus aureus, atypical nevi, autoimmune progesterone dermatitis, and more-and new contributions from international experts, you’ll have a global and current perspective on therapeutic options. Offer your patients the full range of choices and be prepared when your patients do not respond to primary or secondary therapies. Offers guidance for even the most difficult clinical problems by including third and fourth line therapies, as well as standard treatments, so you have options to try when all else fails. Features a summary of each treatment strategy along with detailed discussions of treatment choices so that you can apply the in-depth knowledge of the authors and editors. Presents each chapter in a tabular format, with checklists of diagnostic and investigative pearls and color-coded boxed text, for quick at-a-glance summaries of key details. Includes a full-color clinical photograph of each disease to help you diagnose more effectively. Includes access to the full text, Gold Standard drug database, and all the images online-fully searchable-at expertconsult.com. Covers new and more commonly presenting disorders in 12 new chapters on today’s hot topics, such as methocillin-resistant staphylococcus aureus, atypical nevi, autoimmune progesterone dermatitis, and more. Presents up-to-date evidence and the latest treatments to keep you on the cutting edge of practice. Describes global best practice on the treatment of key disorders through new contributions from international experts.
The first full account of the medieval struggle for Jerusalem, from the seventh to the thirteenth century The history of Jerusalem is one of conflict, faith, and empire. Few cities have been attacked as often and as savagely. This was no less true in the Middle Ages. From the Persian sack in 614 through the bloody First Crusade and beyond, Jerusalem changed hands countless times. But despite these horrific acts of violence, its story during this period is also one of interfaith tolerance and accord. In this gripping history, John D. Hosler explores the great clashes and delicate settlements of medieval Jerusalem. He examines the city's many sieges and considers the experiences of its inhabitants of all faiths. The city's conquerors consistently acknowledged and reinforced the rights of those religious minorities over which they ruled. Deeply researched, this account reveals the way in which Jerusalem's past has been constructed on partial histories--and urges us to reckon with the city's broader historical contours.
Education forms a unique dimension of social status, with qualities that make it especially important to health. It influences health in ways that are varied, present at all stages of adult life, cumulative, self-amplifying, and uniformly positive. Educational attainment marks social status at the beginning of adulthood, functioning as the main bridge between the status of one generation and the next, and also as the main avenue of upward mobility. It precedes the other acquired social statuses and substantially influences them, including occupational status, earnings, and personal and household income and wealth. Education creates desirable outcomes because it trains individuals to acquire, evaluate, and use information. It teaches individuals to tap the power of knowledge. Education develops the learned effectiveness that enables self-direction toward any and all values sought, including health. For decades American health sciences has acted as if social status had little bearing on health. The ascendance of clinical medicine within a culture of individualism probably accounts for that omission. But research on chronic diseases over the last half of the twentieth century forced science to think differently about the causes of disease. Despite the institutional and cultural forces focusing medical research on distinctive proximate causes of specific diseases, researchers were forced to look over their shoulders, back toward more distant causes of many diseases. Some fully turned their orientation toward the social status of health, looking for the origins of that cascade of disease and disability flowing daily through clinics. Why is it that people with higher socioeconomic status have better health than lower status individuals? The authors, who are well recognized for their strength in survey research on a broad national scale, draw on findings and ideas from many sciences, including demography, economics, social psychology, and the health sciences. People who are well educated feel in control of their lives, which encourages and enables a healthy lifestyle. In addition, learned effectiveness, a practical end of that education, enables them to find work that is autonomous and creative, thereby promoting good health. John Mirowsky and Catherine E. Ross are professors in both the Department of Sociology and Population Research Center at the University of Texas at Austin. "Mirowsky and Ross have done the population health community a splendid service by presenting a compelling and complex story for the relationship between social status and health and identifying many important contentious issues for future theoretical debate and empirical exploration. I highly recommend [Education, Social Status, and Health] to all health researchers interested in the social and economic determinants of health and well-being." -Gerry Veenstra, Canadian Journal of Sociology Online
Tens of thousands of readers have relied on this leading text and practitioner reference--now revised and updated--to understand the issues the legal system most commonly asks mental health professionals to address. The volume demystifies the forensic psychological assessment process and provides guidelines for participating effectively and ethically in legal proceedings. Presented are clinical and legal concepts and evidence-based assessment procedures pertaining to criminal and civil competencies, the insanity defense and related doctrines, sentencing, civil commitment, personal injury claims, antidiscrimination laws, child custody, juvenile justice, and other justice-related areas. Case examples, exercises, and a glossary facilitate learning; 19 sample reports illustrate how to conduct and write up thorough, legally admissible evaluations. New to This Edition *Extensively revised to reflect important legal, empirical, and clinical developments. *Increased attention to medical and neuroscientific research. *New protocols relevant to competence, risk assessment, child custody, and mental injury evaluations. *Updates on insanity, sentencing, civil commitment, the Americans with Disabilities Act, Social Security, juvenile and family law, and the admissibility of expert testimony. *Material on immigration law (including a sample report) and international law. *New and revised sample reports.
This is the definitive reference and text for both mental health and legal professionals. The authors offer a uniquely comprehensive discussion of the legal and clinical contexts of forensic assessment, along with best-practice guidelines for participating effectively and ethically in a wide range of criminal and civil proceedings. Presented are findings, instruments, and procedures related to criminal and civil competencies, civil commitment, sentencing, personal injury claims, antidiscrimination laws, child custody, juvenile justice, and more.
Analyses 137 case studies of mass movements of destructive impact from the European Alps in order to outline active and passive measures, monitoring and accepted risk for mass movements of five different types: debris flows from surficial deposits; from bedrock failures; mass movements on volcanoes; and those which are glacier-related; rockfalls and rock avalanches. This information may be useful in dealing with hazards of this type in Canada. Includes many photographs and drawings.
Written and edited by world leaders in nephrology, Comprehensive Clinical Nephrology, 6th Edition, by Drs. John Feehally, Jurgen Floege, Richard J. Johnson, and Marcello Tonelli, provides current information on clinical procedures and conditions as well as the scientific facts and pathophysiology that are foundational to nephrology practice. Ideal for practicing nephrologists, fellows, residents, and internists, it thoroughly covers fluids and electrolytes, hypertension, diabetes, dialysis, and transplantation, and more – all in a single convenient volume. - A "just right" amount of basic science and practical clinical guidance helps you make efficient and informed decisions. - More than 1,500 full-color illustrations highlight key topics and detail pathogenesis for a full range of kidney conditions and clinical management. - New quick-reference boxes with links to clinical guidelines in all relevant chapters. - New chapters on common issues regarding prescribing in kidney disease, palliative nephrology, endemic nephropathies, pathophysiology of chronic kidney disease, and outcomes of dialysis. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips. - Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource. - Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis. - Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases. - Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases. - Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci. - PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America. - Includes regular updates online for the life of the edition. - Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.
This issue of Orthopedics Clinics will be surveying a broad range of topics across sub-specialty areas on Evidence-based Medicine in Orthopedics. Each issue in the series is edited by an experienced team of surgeons from the Campbell Clinic. Articles will discuss the following topics, among others: Use of Tourniquets in Limb Trauma Surgery; Cerebral Palsy; Injection therapies for rotator cuff disease; Antibiotic prophylaxis in shoulder and elbow surgery; venous thromboembolism prophylaxis in shoulder surgery; Patient Reported Outcomes in Foot and Ankle Surgery; and VTED prophylaxis in foot and ankle surgery.
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