The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.
With complete coverage appropriate for residents through experienced pediatric orthopaedic surgeons, Tachdjian's Pediatric Orthopaedics, 6th Edition, continues a 50-year tradition of excellence as the most comprehensive, authoritative guide to diagnosing and treating pediatric musculoskeletal disorders. Editor John Herring, MD, and experts from the Texas Scottish Rite Hospital for Children offer step-by-step instruction and detailed visual guidance on both surgical and non-surgical approaches. It's everything the orthopaedic surgeon needs to know to accurately treat the full spectrum of pediatric orthopaedic conditions and injuries. - Presents complete coverage of the latest knowledge on etiology, imaging, differential diagnosis, growth instrumentation, and non-operative and surgical techniques for a wide range of pediatric orthopaedic conditions. - Provides expert guidance on difficult diagnostic and clinical management issues for your most challenging cases. - Covers today's most effective approaches for management of severe spinal deformities, early onset scoliosis, hip preservation methods, long-term follow-up of trauma conditions, and much more. - Offers superb visual guidance with nearly 2,500 full-color illustrations and 70 videos (many are new!) of pediatric surgical procedures, including a number that highlight clinical examination and unusual clinical findings. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
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