John M. Cohn's Books

Crucible of Science

The Story of the Cori Laboratory

By: John H. Exton

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Crucible of Science

The Story of the Cori Laboratory

By: John H. Exton

Crucible of Science" is the story of a unique laboratory at Washington University in St. Louis, and of Carl and Gerty Cori, the biochemists who established it. Carl and Gerty met and married at medical school in Prague in the 1920s. After graduation, they immigrated to the U.S. to escape deteriorating conditions in Europe. Carl soon received an offer from Washington University to become Pharmacology Chair, and the couple settled in St. Louis. Not only did both Coris go on to win the Nobel Prize, the laboratory they established at the University has since produced some of the most outstanding scientists the U.S. has ever seen. Six laboratory scientists also won Nobel Prizes; few, if any, laboratories can claim such an impressive record. The Coris themselves were instrumental in establishing the then new science of Biochemistry in the U.S. They applied chemical approaches to elucidating the transformations of compounds such as glucose in animal tissues and defined the enzyme catalysts that carried out those transformations. Both scientists were extremely rigorous in designing their experiments and interpreting the results, a habit that ensured their findings were above question. This book examines the careers of both Coris and the other eminent scientists who trained in their laboratory. It notes the Coris' acceptance of women, Jews, and scientists from all over the world, unique during this time period. It analyzes those reasons why the laboratory was so successful in attracting the best trainees and producing premier scientists. Intended for scientists, science historians, and anyone interested in the history of science, "Crucible of Science" is a unique presentation of remarkable careers and personalities, examined within the context of the Coris' laboratory.

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Page Count

259

Publisher

Oxford University Press

Published Date

ISBN 10

0199339872

ISBN 13

9780199339877

Analog Device-Level Layout Automation

By: John M. Cohn,David J. Garrod,Rob A. Rutenbar,Rick Carley

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Analog Device-Level Layout Automation

By: John M. Cohn,David J. Garrod,Rob A. Rutenbar,Rick Carley

This book presents a detailed summary of research on automatic layout of device-level analog circuits that was undertaken in the late 1980s and early 1990s at Carnegie Mellon University. We focus on the work behind the creation of the tools called KOAN and ANAGRAM II, which form part of the core of the CMU ACACIA analog CAD system. KOAN is a device placer for custom analog cells; ANANGRAM II a detailed area router for these analog cells. We strive to present the motivations behind the architecture of these tools, including detailed discussion of the subtle technology and circuit concerns that must be addressed in any successful analog or mixed-signal layout tool. Our approach in organizing the chapters of the book has been to present our algo rithms as a series of responses to these very real and very difficult analog layout problems. Finally, we present numerous examples of results generated by our algorithms. This research was supported in part by the Semiconductor Research Corpora tion, by the National Science Foundation, by Harris Semiconductor, and by the International Business Machines Corporation Resident Study Program. Finally, just for the record: John Cohn was the designer of the KOAN placer; David Garrod was the designer of the ANAGRAM II router (and its predeces sor, ANAGRAM I). This book was architected by all four authors, edited by John Cohn and Rob Rutenbar, and produced in finished form by John Cohn.

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Page Count

299

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461527562

ISBN 13

9781461527565

Retinal Dystrophy Gene Atlas

By: Sarwar Zahid,Kari Branham,Dana Schlegel,Mark E. Pennesi,Michel Michaelides,John Heckenlively,Thiran Jayasundera

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Retinal Dystrophy Gene Atlas

By: Sarwar Zahid,Kari Branham,Dana Schlegel,Mark E. Pennesi,Michel Michaelides,John Heckenlively,Thiran Jayasundera

Classically, photo atlases of retinal dystrophies have been divided into sections that describe and depict a particular retinal finding or disease, after which a differential diagnosis of potential diseases or mutated genes is provided. However, given the rapid improvement in molecular diagnostics, and the exponential increase in our understanding of the phenotypes caused by each mutated gene, the paradigm has changed. Physicians are now more interested in the variable expressivity associated with mutations in each individual gene. Therefore, Retinal Dystrophy Gene Atlas catalogs the different phenotypes that have been reported with each mutated gene. Each section describes a gene and its known clinical phenotypes and features of disease, along with retinal photos of affected patients. Written by prominent retinal dystrophy specialists from the largest dystrophy centers worldwide, Retinal Dystrophy Gene Atlas contains more than 80 chapters, each of which describes the clinical and photographic manifestations of a specific gene. The chapters include stunning clinical color photographs of the retina, autofluorescence imaging, electrophysiologic findings, and cross-sectional imaging. Retinal Dystrophy Gene Atlas serves as a resource to aid genetic diagnosis in patients with retinal dystrophies.

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Page Count

250

Publisher

Springer

Published Date

ISBN 10

3319108670

ISBN 13

9783319108674

Ethics of Armed Conflict

A Cosmopolitan Just War Theory

By: John W. Lango

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Ethics of Armed Conflict

A Cosmopolitan Just War Theory

By: John W. Lango

Just war theory exists to stop armies and countries from using armed force without good cause. But how can we judge whether a war is just? In this original book, John W. Lango takes some distinctive approaches to the ethics of armed conflict. DT A revisionist approach that involves generalising traditional just war principles, so that they are applicable by all sorts of responsible agents to all forms of armed conflict DT A cosmopolitan approach that features the Security Council DT A preventive approach that emphasises alternatives to armed force, including negotiation, nonviolent action and peacekeeping missions DT A human rights approach that encompasses not only armed humanitarian intervention but also armed invasion, armed revolution and all other forms of armed conflict Lango shows how these can be applied to all forms of armed conflict, however large or small: from interstate wars to UN peacekeeping missions, and from civil wars counter-insurgency and counter-terrorism operations.

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Page Count

256

Publisher

Edinburgh University Press

Published Date

ISBN 10

0748645764

ISBN 13

9780748645763

Hadamard Matrix Analysis and Synthesis

With Applications to Communications and Signal/Image Processing

By: Rao K. Yarlagadda,John E. Hershey

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Hadamard Matrix Analysis and Synthesis

With Applications to Communications and Signal/Image Processing

By: Rao K. Yarlagadda,John E. Hershey

Hadamard Matrix Analysis and Synthesis: With Applications to Communications and Signal/Image Processing presents the basic concepts of Sylvester's construction of Hadamard matrices, the eigenvalue-eigenvector decompositions, along with its relationship to Fourier transforms. Relevant computational structures are included for those interested in implementing the Hadamard transform. The 2-dimensional Hadamard transform is discussed in terms of a 1- dimensional transform. The applications presented touch on statistics, error correction coding theory, communications signaling, Boolean function analysis and synthesis, image processing, sequence theory (maximal length binary sequences, composite sequences, and Thue-Morse sequences) and signal representation. An interesting application of the Hadamard transform to images is the Naturalness Preserving Transform (NPT), which is presented. The NPT provides a way to encode an image that can be reconstructed when it is transmitted through a noisy or an unfriendly channel. The potential applications of the Hadamard transform are wide and the book samples many of the important concepts among a vast field of applications of the transform. Hadamard Matrix Analysis and Synthesis: With Applications to Communications and Signal/Image Processing serves as an excellent reference source and may be used as a text for advanced courses on the topic.

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Page Count

120

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461563135

ISBN 13

9781461563136

Reading EEGs: A Practical Approach

By: L. John Greenfield,James D. Geyer,Paul R. Carney

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Reading EEGs: A Practical Approach

By: L. John Greenfield,James D. Geyer,Paul R. Carney

Reading EEGs: A Practical Approach focuses on pattern recognition and pattern comparison. The concepts of pattern recognition are developed in a logical fashion based on appearance rather than disease process. The book teaches waveform recognition so that the reader can generate a differential diagnosis based on that recognition. This book also incorporates a question-and-answer format that is effective for students at multiple levels of training. A unique feature of the book is that it follows a teaching methodology in which concepts are developed sequentially and logically.

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Page Count

368

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

145114864X

ISBN 13

9781451148640

Book's by John M. Cohn

Crucible of Science

Crucible of Science

Analog Device-Level Layout Automation

Analog Device-Level Layout Automation

Retinal Dystrophy Gene Atlas

Retinal Dystrophy Gene Atlas

Ethics of Armed Conflict

Ethics of Armed Conflict

Hadamard Matrix Analysis and Synthesis

Hadamard Matrix Analysis and Synthesis

Reading EEGs: A Practical Approach

Reading EEGs: A Practical Approach

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