Images of loss and yearning played a crucial role in literary texts written in the later part of the twentieth century. Despite deep cultural differences, novelists from Africa, the Caribbean, Great Britain, and the United States share a sense that the economic, social, and political forces associated with late modernity have evoked widespread nostalgia within the communities in which they write. In this original and wide-ranging study, John J. Su explores the relationship between nostalgia and ethics in novels across the English-speaking world. He challenges the tendency in literary studies to characterise memory as positive and nostalgia as necessarily negative. Instead, this book argues that nostalgic fantasies are crucial to the ethical visions presented by topical novels. From Jean Rhys to Wole Soyinka and from V. S. Naipaul to Toni Morrison, Su identifies nostalgia as a central concern in the twentieth-century novel.
Note to Readers: Publisher does not guarantee quality or access to any included digital components if book is purchased through a third-party seller. This essential companion to the DSM uniquely integrates intersectionality and resilience that helps mental health practitioners assess clients from a strength-based perspective. The third edition expands the section on neurocognitive disorders to include traumatic brain injury, includes more information on assessment and treatment of common childhood disorders, and brings a new focus on the impact of today’s culture wars and their impact on mental health professionals, policy, and clients Also new to the third edition is an emphasis on meta-analysis literature and a module on wellbeing discussing neuroscience and wellness concepts in relation to a strengths-based approach to diagnosis. By demonstrating how to practically integrate diversity and intersectionality into the diagnostic process rather than limiting assessment to a purely problem-focused diagnostic label, this successful textbook strengthens the DSM for social workers and other mental health practitioners by promoting the inclusion of intersectionality, resiliency, culture, spirituality, and community into practice. It includes multiple case studies featuring complex, real life scenarios that offer a greater depth of learning by demonstrating how a strength-based assessment of the whole person can lead to more effective and successful treatment. Discussion questions promote critical thinking, key points in each chapter highlight and reinforce important concepts, and abundant web resources encourage additional study. The book also includes a robust instructor package. Purchase of the print edition includes access to Ebook format. New to the Third Edition: Adds traumatic brain injury to neurocognitive disorders section Expands information on treatment of common childhood disorders Emphasizes meta-analysis literature Discusses neuroscience and wellness concepts in relation to a strengths-based approach to diagnosis Focuses on wellness and health care delivery in the context of today’s culture wars Key Features: Delivers a unique formulation integrating intersectionality and resilience to provide strengths-based assessment and treatment Demonstrates the rationale for strengths-based DSM practice Includes real-life case scenarios for complex problem-solving Uses a standard format for each disorder for quick access to information Reviews key literature on disorders and evidence-based best practices Provides classroom questions and activities to foster critical thinking Identifies professional and scholarly activities to promote increased effectiveness in diagnosis
Invention and innovation are not the same. When we come up with an exciting and original new idea, by itself that idea is not an innovation. It is simply an invention, possibly a great invention, but at that point the hard work is still to be done.
Self-organizing Neural Maps: From Retina to Tectum describes the underlying processes that determine how retinal fibers self-organize into an orderly visual map. The formation of neural maps is a fundamental organizing concept in neurodevelopment that can shed light on developmental mechanisms and the functions of genes elsewhere. The book presents a summary of research in the retinotectal field with an ultimate goal of synthesizing how underlying mechanisms in neural development harmoniously come together to create life. A broad spectrum of neuroscientists and biomedical scientists with differing backgrounds and varied expertise will find this book useful. - Describes the mechanisms relating to the developmental wiring of the retinotectal system - Brings together the state-of-the-art research in axon guidance and neuronal activity mechanisms in map formation - Focuses on topographical maps and inclusion of multiple animal models, from fish to mammals - Explores the molecular guidance and activity dependent cue components involved in neurodevelopment
Psychology is of interest to academics from many fields, as well as to the thousands of academic and clinical psychologists and general public who can't help but be interested in learning more about why humans think and behave as they do. This award-winning twelve-volume reference covers every aspect of the ever-fascinating discipline of psychology and represents the most current knowledge in the field. This ten-year revision now covers discoveries based in neuroscience, clinical psychology's new interest in evidence-based practice and mindfulness, and new findings in social, developmental, and forensic psychology.
Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers. Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.
The 2nd Edition of this comprehensive text features practical guidance on how to diagnose and manage the neurological effects and complications of every major category of recreationally used drugs. Book jacket.
A resource of unparalleled thoroughness, The APSAC Handbook on Child Maltreatment, Second Edition provides critical information for those who dedicate their working lives to alleviating the causes and consequences of child abuse and neglect. Written in engaging but straightforward language and committed to immediate application, this comprehensive handbook covers physical and sexual abuse, all forms of neglect, and psychological maltreatment. Experts in a variety of specialized areas have designed each chapter to inform professionals in mental health, law, medicine, law enforcement, and child protective services of the most current empirical research and literature available as well as strategies for intervention and prevention.
Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.
This new edition of Fungi in Ecosystem Processes continues the unique approach of examining the roles of fungi from the perspective of ecosystem functions. It explores how fungi have adapted to survive within particular constraints, how they help to maintain homeostasis in ecosystems, how they facilitate resistance to perturbations, and how they influence the communities of other organisms. Updated and revised, the second edition Expands the section on plant pathogens, invasive species, and insect–fungal interactions Provides more extensive coverage on insect–fungal interactions, including entomopathogens, the links between entomopathogens and endophytes, and symbiotic and mutualistic interactions Adds a new section on fungi in the built environment Presents new material on below-ground to above-ground interactions mediated through fungi, such as mycorrhizal signaling systems for herbivory defense The book also includes expanded coverage of the role of fungi in suppressive soils, aquatic and marine fungi, modern methods of following food chains in fungal–invertebrate trophic interactions, and the physiology of nutrient uptake by mycorrhizae. A necessary update and expansion to previous material, this book provides an essential reference on the current understanding of fungal roles in ecosystem processes. It also identifies directions for future study, including an emphasis on the need for further research on fungi in built environments.
Imagination and the Contemporary Novel examines the global preoccupation with the imagination among literary authors with ties to former colonies of the British Empire since the 1960s. John Su draws on a wide range of authors including Peter Ackroyd, Monica Ali, Julian Barnes, André Brink, J. M. Coetzee, John Fowles, Amitav Ghosh, Nadine Gordimer, Hanif Kureishi, Salman Rushdie and Zadie Smith. This study rehabilitates the category of imagination in order to understand a broad range of contemporary Anglophone literature. The responses of such literature to shifts in global capitalism have often been misunderstood by the dominant categories of literary studies, the postmodern and the postcolonial. As both an insightful critique into the themes that drive a range of today's best novelists and a bold restatement of what the imagination is and what it means for contemporary culture, this book breaks new ground in the study of twenty-first-century literature.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Offering authoritative coverage of all aspects of diagnosing, treating, and preventing the progression of chronic kidney disease (CKD), this highly regarded handbook is an invaluable resource for nephrologists, internists, nurse practitioners, physician assistants, and other healthcare professionals who care for early-stage CKD patients. Incorporating the considerable advances in the field since the previous edition, Handbook of Chronic Kidney Disease Management, 2nd Edition, provides a truly global perspective on managing patients with mild to moderate CKD.
In the past ten years, heteroepitaxy has continued to increase in importance with the explosive growth of the electronics industry and the development of a myriad of heteroepitaxial devices for solid state lighting, green energy, displays, communications, and digital computing. Our ever-growing understanding of the basic physics and chemistry underlying heteroepitaxy, especially lattice relaxation and dislocation dynamic, has enabled an ever-increasing emphasis on metamorphic devices. To reflect this focus, two all-new chapters have been included in this new edition. One chapter addresses metamorphic buffer layers, and the other covers metamorphic devices. The remaining seven chapters have been revised extensively with new material on crystal symmetry and relationships, III-nitride materials, lattice relaxation physics and models, in-situ characterization, and reciprocal space maps.
Learn the fundamentals of materials design with this all-inclusive approach to the basics in the field Study of materials science is an important aspect of curricula at universities worldwide. This text is designed to serve students at a fundamental level, positioning materials design as an essential aspect of the study of electronics, medicine, and energy storage. Now in its 3rd edition, Principles of Inorganic Materials Design is an introduction to relevant topics including inorganic materials structure/property relations and material behaviors. The new edition now includes chapters on computational materials science, intermetallic compounds, and covalent compounds. The text is meant to aid students in their studies by providing additional tools to study the key concepts and understand recent developments in materials research. In addition to the many topics covered, the textbook includes: • Accessible learning tools to help students better understand key concepts • Updated content including case studies and new information on computational materials science • Practical end-of-chapter exercises to assist students with the learning of the material • Short biographies introducing pioneers in the field of inorganic materials science For undergraduates just learning the material or professionals looking to brush up on their knowledge of current materials design information, this text covers a wide range of concepts, research, and topics to help round out their education. The foreword to the first edition was written by the 2019 Chemistry Nobel laureate Prof. John B. Goodenough.
The theory of characteristic classes provides a meeting ground for the various disciplines of differential topology, differential and algebraic geometry, cohomology, and fiber bundle theory. As such, it is a fundamental and an essential tool in the study of differentiable manifolds. In this volume, the authors provide a thorough introduction to characteristic classes, with detailed studies of Stiefel-Whitney classes, Chern classes, Pontrjagin classes, and the Euler class. Three appendices cover the basics of cohomology theory and the differential forms approach to characteristic classes, and provide an account of Bernoulli numbers. Based on lecture notes of John Milnor, which first appeared at Princeton University in 1957 and have been widely studied by graduate students of topology ever since, this published version has been completely revised and corrected.
The science of the virus and its effects and the clinical approaches to its treatment and transmission prevention are placed in the context of the history and epidemiology of the HIV-AIDS pandemic. Each organ system of the body is explored as to manifestations of the disease, treatment now and in the future, as well as what the disease has taught us about the immune response. The science of epidemiology, which is so important in allowing for tracking of the disease and potential limitation of transmission, is another aspect of AIDS explored in detail. The pandemic manifests differently in different parts of the world, and the relevance of the volume is enhanced by its international group of contributors. No other text provides the historical and epidemiological context of this disease along with an update of diagnosis and treatment. The underlying science and epidemiology of AIDS are not neglected, so the student or clinician who is treating patients with AIDS can gain a full understanding of HIV/AIDS in individual patients and in their communities.
Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up. - Includes new chapters on Cancer Metabolism and Clinical Trial Designs in Oncology and a standalone chapter on lifestyles and cancer prevention. - Features extensive updates including the latest clinical practice guidelines, decision-making algorithms, and clinical trial implications, as well as new content on precision medicine, genetics, and PET/CT imaging. - Includes revised diagnostic and treatment protocols for medical management, surgical considerations, and radiation oncology therapies, stressing a multispecialty, integrated approach to care. - Helps you find information quickly with updated indexing related to management recommendations, focused fact summaries, updated key points at the beginning of each chapter ideal for quick reference and board review, and algorithms for patient evaluation, diagnosis, and treatment options. - Offers more patient care coverage in disease chapters, plus new information on cancer as a chronic illness and cancer survivorship. - Discusses today's key topics such as immuno-oncology, functional imaging, precision medicine, the application of genetics in pathologic diagnosis and sub-categorization of tumors as well as the association of chronic infectious diseases such as HIV and cancer. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. - Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. - Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. - Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. - Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. - Access the entire text and illustrations online, fully searchable, at Expert Consult.
The book focuses on the design, materials, process, fabrication, and reliability of advanced semiconductor packaging components and systems. Both principles and engineering practice have been addressed, with more weight placed on engineering practice. This is achieved by providing in-depth study on a number of major topics such as system-in-package, fan-in wafer/panel-level chip-scale packages, fan-out wafer/panel-level packaging, 2D, 2.1D, 2.3D, 2.5D, and 3D IC integration, chiplets packaging, chip-to-wafer bonding, wafer-to-wafer bonding, hybrid bonding, and dielectric materials for high speed and frequency. The book can benefit researchers, engineers, and graduate students in fields of electrical engineering, mechanical engineering, materials sciences, and industry engineering, etc.
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself (the complex of DNA, histones and non-histone proteins referred to as chromatin), and its distribution within a functionally compartmentalized nucleus. This architectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information.
Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.
Provides a modern, practical approach to the understanding and measurement procedures relevant to the fracture of brittle materials This book examines the testing and analysis of the fracture of brittle materials. Expanding on the measurement and analysis methodology contained in the first edition, it covers the relevant measurements (toughness and strength), material types, fracture mechanics, measurement techniques, reliability and lifetime predictions, microstructural considerations, and material/test selection processes appropriate for the analysis of the fracture behavior of brittle materials. The Fracture of Brittle Materials: Testing and Analysis, Second Edition summarizes the concepts behind the selection of a test procedure for fracture toughness and strength, and goes into detail on how the statistics of fracture can be used to assure reliability. It explains the importance of the role of microstructure in these determinations and emphasizes the use of fractographic analysis as an important tool in understanding why a part failed. The new edition includes a significant quantity of material related to the fracture of biomaterials, and features two new chapters—one on thermal shock, the other on the modeling of the fracture process. It also expands on a discussion of how to treat the statistics of fracture strength data to ensure reliability. Provides practical analysis of fracture toughness and strength Introduces the engineering and materials student to the basic concepts necessary for analyzing brittle fracture Contains new statistical analysis procedures to allow for the prediction of the safe design of brittle components Contains real-world examples to assist the reader in applying the concepts to their own research, material development, and quality-control needs The Fracture of Brittle Materials: Testing and Analysis, Second Edition is an important resource for all students, technicians, engineers, scientists, and researchers involved in the study, analysis, creation, or testing of ceramics.
In addition to those aircraft built in Eastern European nations for domestic use and export, warplanes of the non-aligned nations are also described and illustrated. Descriptions are complimented by high-quality three-view drawings and large photographs, assisting positive identification.
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