“The compelling story of a colony besieged by meteorological, epidemiological, economic, and manmade catastrophes only to arise like the phoenix.” —Orville Vernon Burton, author of The Age of Lincoln During South Carolina’s settlement, a cadre of men rose to political and economic prominence, while ordinary colonists, enslaved Africans, and indigenous groups became trapped in a web of violence and oppression. John J. Navin explains how eight English aristocrats, the Lords Proprietors, came to possess the vast Carolina grant and then enacted elaborate plans to recruit and control colonists as part of a grand moneymaking scheme. But those plans went awry, and the mainstays of the economy became hog and cattle ranching, lumber products, naval stores, deerskin exports, and the calamitous Indian slave trade. The settlers’ relentless pursuit of wealth set the colony on a path toward prosperity but also toward a fatal dependency on slave labor. Rice would produce immense fortunes in South Carolina, but not during the colony’s first fifty years. Religious and political turmoil instigated by settlers from Barbados eventually led to a total rejection of proprietary authority. Using a variety of primary sources, Navin describes challenges that colonists faced, setbacks they experienced, and the effects of policies and practices initiated by elites and proprietors. Storms, fires, epidemics, and armed conflicts destroyed property, lives, and dreams. Threatened by the Native Americans they exploited, by the Africans they enslaved, and by their French and Spanish rivals, South Carolinians lived in continual fear. For some it was the price they paid for financial success. But for most there were no riches, and the possibility of a sudden, violent death was overshadowed by the misery of their day-to-day existence.
I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into 4 sections: antibiotics, anti-fungal drugs, anti-parasitic drugs and anti-viral drugs, and is highly structured for ease of reference.Within each section, each chapter is structured to cover susceptibility, formulations and dosing (adult and paediatric), pharmacokinetics and pharmacodynamics, toxicity and drug distribution, detailed discussion regarding clinical uses, a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with a vast number of contributors spanning Europe, Africa, Asia, Australia, South America, the US and Canada, the sixth edition adopts a truly global approach. It will remain invaluable for anyone using antimicrobial agents in their clinical practice and provides in a systematic and concise manner all the information required when treating infections requiring antimicrobial therapy. Kucers' The Use of Antibiotics is available free to purchasers of the books as an electronic version on line or on your desktop: It provides access to the entire 2-volume print material It is fully searchable, so you can find the relevant information you need quickly Live references are linked to PubMed referring you to the latest journal material Customise the contents - you can highlight sections and make notes Comments can be shared with colleagues/tutors for discussion, teaching and learning The text can also be reflowed for ease of reading Text and illustrations copied will be automatically referenced to Kucers' The Use of Antibiotics
Since its establishment 114 years ago, the Detroit Athletic Club (DAC) has played a crucial role in the amazing history of the City of Detroit. Originally a club for amateur athletes, it was reorganized in 1913 by prominent automobile and industrial leaders. In that year, Albert Kahn, a renowned architect, designed the magnificent six-story clubhouse that still stands in the heart of Detroit's theatre and sports district. Beginning with the birth of the original club on Woodward Avenue in 1887, this book chronicles the history of the DAC up to the present, in over 200 vintage photographs-many never before seen outside of the club. Images gathered from the club's archives cover the formative years at the first club, the building and opening of the new club, the DAC's great athletic traditions, its membership and staff, social activities, the art of the DAC and its magnificent restoration at the end of the 20th century.
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